MRC Epidemiology Unit

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There are 4470 publications in the database

Intensive versus standard multifactorial cardiovascular risk factor control in screen-detected type 2 diabetes: 5-year and longer-term modelled outcomes of the ADDITION-Leicester study.

Webb D, Dales J, Zaccardi F, Hill S, Moore C, Farooqi A, Griffin SJ, Davies M, Khunti K

Diabetes/metabolism research and reviews. Jul 2018

(DOI : 10.1002/dmrr.3111)

Assessing the causal association of glycine with risk of cardio-metabolic diseases.

Wittemans LBL, Lotta LA, Oliver-Williams C, Stewart ID, Surendran P, Karthikeyan S, Day FR, Koulman A, Imamura F, Zeng L, Erdmann J, Schunkert H, Khaw KT, Griffin JL, Forouhi NG, Scott RA, Wood AM, Burgess S, Howson JMM, Danesh J, Wareham NJ, Butterworth AS, Langenberg C

Nature communications. Jul 2018

(DOI : 10.1038/s41467-019-08936-1)

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Kraja AT, Graff M, Have CT, Yanek LR, Feitosa MF, Arking DE, Chasman DI, Young K, Ligthart S, Weiss S, Luan J, Giulianini F, Li-Gao R, Hartwig FP, Wang L, Richardson TG, Ghanbari M, Wojczynski MK, Lee WJ, Ryan KA, Bielinski SJ, Bowden DW, Broeckel U, Christensen K, Chu AY, Corley J, Cox SR, Uitterlinden AG, Rivadeneira F, Daw EW, van Heemst D, de Las Fuentes L, Tzoulaki I, Ahluwalia TS, de Mutsert R, Erzurumluoglu AM, Perry JA, Forouhi NG, Harris SE, Hemani G, Hunt SC, Irvin MR, Justice AE, Kerrison ND, Lin KH, Mathias RA, Lee JH, Nauck M, Noordam R, Ong KK, Pattie A, Petersmann A, Ribel-Madsen R, Rohde R, Sandow K, Schnurr TM, Sofer T, Starr JM, Teumer A, Timpson NJ, de Haan HG, Wang Y, Weeke PE, Williams C, Witte DR, Wareham NJ, Vestergaard H, Turner ST, Sheu WH, Rosendaal FR, Ikram MA, Franco OH, Ridker PM, Pedersen O, Nohr EA, Newman AB, Linneberg A, Langenberg C, Kilpeläinen TO, Kardia SLR, Jørgensen ME, Jørgensen T, Sørensen TIA, Homuth G, Hansen T, Goodarzi MO, Deary IJ, Christensen C, Chen YI, Chakravarti A, Brandslund I, Taylor KD, Wilson JG, Rodriguez S, Davies G, Horta BL, Rao DC, Grarup N, Arnett DK, Hayward C, Vaidya D, Mook-Kanamori DO, Levy D, Loos RJF, Dehghan A, Elliott P, Scott RA, Becker DM, de Andrade M, Province MA, Meigs JB, Rotter JI, North KE

American journal of human genetics. Jul 2018

(DOI : 10.1016/j.ajhg.2018.12.001)

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, Chen J, Nodzenski M, Schnurr TM, Zafarmand MH, Bradfield JP, Grarup N, Kooijman MN, Li-Gao R, Geller F, Ahluwalia TS, Paternoster L, Rueedi R, Huikari V, Hottenga JJ, Lyytikäinen LP, Cavadino A, Cousminer DL, Thiering E, Wang CA, Have CT, Vilor-Tejedor N, Joshi PK, Painter JN, Ntalla I, Myhre R, Pitkänen N, van Leeuwen EM, Joro R, Lagou V, Barton SJ, Inskip HM, Holloway JW, Marullo L, Lunetta KL, Murabito JM, Relton CL, Hivert MF, Mentch FD, Langenberg C, Luan J, Scott RA, Zhao JH, Hemani G, Ring SM, Bennett AJ, Gaulton KJ, Fernandez-Tajes J, van Zuydam NR, Medina-Gomez C, de Haan HG, Rosendaal FR, Kutalik Z, Marques-Vidal P, Willemsen G, Mbarek H, Müller-Nurasyid M, Standl M, Appel EVR, Fonvig CE, Trier C, Murcia M, Bustamante M, Bonas-Guarch S, Hougaard DM, Mercader JM, Linneberg A, Schraut KE, Lind PA, Medland SE, Chai JF, Panoutsopoulou K, Sánchez F, Torrents D, Willems S, Atalay M, Kovacs P, Prokopenko I, Tuke MA, Yaghootkar H, Ruth KS, Jones SE, Loh PR, Murray A, Weedon MN, Tönjes A, Stumvoll M, Lakka TA, van Duijn CM, Kiess W, Körner A, Niinikoski H, Pahkala K, Raitakari OT, Jacobsson B, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Montgomery GW, Campbell H, Wilson JF, Vrijheid M, de Geus EJCN, Kadarmideen HN, Holm JC, Beilin LJ, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Hattersley AT, Spector TD, Kähönen M, Viikari JS, Lehtimäki T, Boomsma DI, Sebert S, Vollenweider P, Sørensen TIA, Bisgaard H, Bønnelykke K, Murray JC, Melbye M, Nohr EA, Mook-Kanamori DO, Rivadeneira F, Hofman A, Felix JF, Jaddoe VWV, Hansen T, Pisinger C, Vaag AA, Pedersen O, Uitterlinden AG, Järvelin MR, Power C, Hyppönen E, Scholtens DM, Lowe WL, Davey Smith G, Timpson NJ, Morris AP, Wareham NJ, Hakonarson H, Grant SFA, Frayling TM, Lawlor DA, Njølstad PR, Johansson S, Ong KK, McCarthy MI, Perry JR, Evans DM, Freathy RM

Nature genetics. Jun 2018

(DOI : 10.1038/s41588-019-0403-1)

Associations of context-specific sitting time with markers of cardiometabolic risk in Australian adults.

Dempsey PC, Hadgraft NT, Winkler EAH, Clark BK, Buman MP, Gardiner PA, Owen N, Lynch BM, Dunstan DW

The international journal of behavioral nutrition and physical activity. Jun 2018

(DOI : 10.1186/s12966-018-0748-3)

Age at menarche and the future risk of gestational diabetes: a systematic review and dose response meta-analysis.

Petry CJ, Ong KK, Dunger DB

Acta diabetologica. Jun 2018

(DOI : 10.1007/s00592-018-1214-z)

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.

Jackson VE, Shrine N, Bartz TM, Obeidat M, Barr RG, Beaty TH, Brusselle GG, DeMeo DL, Gharib SA, Hall IP, London SJ, O'Connor GT, Strachan DP, Vonk JM, Zhou X, Bossé Y, Manichaikul A, Lahousse L, Wain LV, Tobin MD

Nature genetics. Jun 2018

(DOI : 10.1038/s41588-018-0342-2)

Tuberculosis and diabetes: bidirectional association in a UK primary care data set.

Pearson F, Huangfu P, McNally R, Pearce M, Unwin N, Critchley JA

Journal of Epidemiology and Community Health. Jun 2018

(DOI : 10.1136/jech-2018-211231)

Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.

Burgess S, Staley JR, Freitag DF, Nielsen SF, Willeit P, Young R, Surendran P, Kamstrup PR, Benn M, Langsted A, Ford I, Trompet S, Jukema JW, Sattar N, Di Angelantonio E, Saleheen D, Howson JMM, Nordestgaard BG, Butterworth AS, Danesh J

JAMA cardiology. Jun 2018

(DOI : 10.1001/jamacardio.2018.1470)

Associations between the maternal circulating lipid profile in pregnancy and fetal imprinted gene alleles: a cohort study.

Petry CJ, Koulman A, Lu L, Jenkins B, Furse S, Prentice P, Matthews L, Hughes IA, Acerini CL, Ong KK, Dunger DB

Reproductive biology and endocrinology : RB&E. Jun 2018

(DOI : 10.1186/s12958-018-0399-x)

Supermarket policies on less-healthy food at checkouts: Natural experimental evaluation using interrupted time series analyses of purchases.

Ejlerskov KT, Sharp SJ, Stead M, Adamson AJ, White M, Adams J

PLoS Medicine. Jun 2018

(DOI : 10.1371/journal.pmed.1002712)

How good are GPs at adhering to a pragmatic trial protocol in primary care? Results from the ADDITION-Cambridge cluster-randomised pragmatic trial.

Laxy M, Wilson ECF, Boothby CE, Griffin SJ

BMJ Open. Jun 2018

(DOI : 10.1136/bmjopen-2016-015295)

Food based dietary patterns and chronic disease prevention.

Schulze MB, Martínez-González MÁ, Fung TT, Lichtenstein AH, Forouhi NG

BMJ (Clinical research ed.). Jun 2018

(DOI : 10.1136/bmj.k2396)

Dietary fat and cardiometabolic health: evidence, controversies, and consensus for guidance.

Forouhi NG, Krauss RM, Taubes G, Willett W

BMJ (Clinical research ed.). Jun 2018

(DOI : 10.1136/bmj.k2139)

Dietary and nutritional approaches for prevention and management of type 2 diabetes.

Forouhi NG, Misra A, Mohan V, Taylor R, Yancy W

BMJ (Clinical research ed.). Jun 2018

(DOI : 10.1136/bmj.k2234)

Exploring the emergence and evolution of population patterns of leisure-time physical activity through agent-based modelling.

Garcia LMT, Diez Roux AV, Martins ACR, Yang Y, Florindo AA

The international journal of behavioral nutrition and physical activity. Jun 2018

(DOI : 10.1186/s12966-018-0750-9)

Time trends in adherence to UK dietary recommendations and associated sociodemographic inequalities, 1986-2012: a repeated cross-sectional analysis.

Yau A, Adams J, Monsivais P

European Journal of Clinical Nutrition. Jun 2018

(DOI : 10.1038/s41430-018-0347-z)

Impact of sit-stand desks at work on energy expenditure, sitting time and cardio-metabolic risk factors: Multiphase feasibility study with randomised controlled component.

Mantzari E, Galloway C, Wijndaele K, Brage S, Griffin SJ, Marteau TM

Preventive medicine reports. Jun 2018

(DOI : 10.1016/j.pmedr.2018.11.012)

A randomised controlled trial of the effect of providing online risk information and lifestyle advice for the most common preventable cancers: study protocol.

Usher-Smith JA, Masson G, Mills K, Sharp SJ, Sutton S, Klein WMP, Griffin SJ

BMC Public Health. Jun 2018

(DOI : 10.1186/s12889-018-5712-2)

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M, Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimäki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bossé Y, Brandsma CA, Chen Z, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Soler Artigas M, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Yerges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kähönen M, Polasek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Järvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers DA, Cho MH, Strachan DP, Hall IP, Tobin MD, Wain LV, Understanding Society Scientific Group

Nature genetics. Jun 2018

(DOI : 10.1038/s41588-018-0321-7)

Circulating insulin-like growth factor I in relation to melanoma risk in the European prospective investigation into cancer and nutrition.

Bradbury KE, Appleby PN, Tipper SJ, Travis RC, Allen NE, Kvaskoff M, Overvad K, Tjønneland A, Halkjaer J, Cervenka I, Mahamat-Saleh Y, Bonnet F, Kaaks R, Fortner RT, Boeing H, Trichopoulou A, La Vecchia C, Stratigos AJ, Palli D, Grioni S, Matullo G, Panico S, Tumino R, Peeters PH, Bueno-de-Mesquita HB, Ghiasvand R, Veierød MB, Weiderpass E, Bonet C, Molina E, Huerta JM, Larrañaga N, Barricarte A, Merino S, Isaksson K, Stocks T, Ljuslinder I, Hemmingsson O, Wareham N, Khaw KT, Gunter MJ, Rinaldi S, Tsilidis KK, Aune D, Riboli E, Key TJ

International journal of cancer. Jun 2018

(DOI : 10.1002/ijc.31854)

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

Kilpeläinen TO, Bentley AR, Noordam R, Sung YJ, Schwander K, Winkler TW, Chasman DI, Manning A, Ntalla I, Aschard H, Brown MR, de Las Fuentes L, Franceschini N, Vojinovic D, Aslibekyan S, Feitosa MF, Musani SK, Wang H, Wang Z, Bartz TM, Bielak LF, Campbell A, Dorajoo R, Fisher V, Hartwig FP, Horimoto ARVR, Lohman KK, Marten J, Smith AV, Tajuddin SM, Alver M, Amini M, Boissel M, Chai JF, Chen X, Divers J, Evangelou E, Graff M, Harris SE, Hsu FC, Jackson AU, Zhao JH, Kraja AT, Kühnel B, Laguzzi F, Lyytikäinen LP, Nolte IM, Rauramaa R, Riaz M, Robino A, Rueedi R, Stringham HM, Takeuchi F, van der Most PJ, Varga TV, Verweij N, Ware EB, Yanek LR, Amin N, Arnett DK, Boerwinkle E, Brumat M, Cade B, Canouil M, Chen YI, Concas MP, Connell J, de Mutsert R, de Silva HJ, de Vries PS, Demirkan A, Ding J, Eaton CB, Faul JD, Friedlander Y, Ghanbari M, Giulianini F, Harris TB, Heikkinen S, Heng CK, Hunt SC, Ikram MA, Jonas JB, Koh WP, Komulainen P, Krieger JE, Kritchevsky SB, Kutalik Z, Kuusisto J, Langefeld CD, Langenberg C, Launer LJ, Leander K, Lemaitre RN, Lewis CE, Liang J, Mägi R, Manichaikul A, Meitinger T, Metspalu A, Milaneschi Y, Mohlke KL, Mosley TH, Murray AD, Nalls MA, Nelson CP, Norris JM, Palmer ND, Papanicolau GJ, Pazoki R, Pedersen NL, Peters A, Peyser PA, Polasek O, Porteous DJ, Poveda A, Raitakari OT, Rich SS, Robinson JG, Rose LM, Rudan I, Schreiner PJ, Scott RA, Sims M, Smith JA, Snieder H, Sofer T, Starr JM, Sternfeld B, Strauch K, Tang H, Taylor KD, Tsai MY, Tuomilehto J, Uitterlinden AG, van Heemst D, Voortman T, Waldenberger M, Wennberg P, Wilson G, Xiang YB, Yuan JM, Zhao W, Zonderman AB, Becker DM, Boehnke M, Bowden DW, de Faire U, Deary IJ, Elliott P, Esko T, Freedman BI, Froguel P, Gasparini P, Gieger C, Kato N, Laakso M, Lakka TA, Lehtimäki T, Magnusson PKE, Oldehinkel AJ, Penninx BWJH, Samani NJ, Shu XO, van der Harst P, Van Vliet-Ostaptchouk JV, Vollenweider P, Wagenknecht LE, Wang YX, Wareham NJ, Weir DR, Zheng W, Evans MK, Franks PW, Gudnason V, Hayward C, Horta BL, Kelly TN, North KE, Pereira AC, Ridker PM, Tai ES, van Dam RM, Fox ER, Kardia SLR, Liu CT, Mook-Kanamori DO, Province MA, Redline S, van Duijn CM, Rotter JI, Gauderman WJ, Psaty BM, Rice K, Munroe PB, Fornage M, Cupples LA, Rotimi CN, Morrison AC, Rao DC, Loos RJF

Nature communications. Jun 2018

(DOI : 10.1038/s41467-018-08008-w)

Individual and combined impact of lifestyle factors on atrial fibrillation in apparently healthy men and women: The EPIC-Norfolk prospective population study.

Di Benedetto L, Michels G, Luben R, Khaw KT, Pfister R

European Journal of Preventive Cardiology. Jun 2018

(DOI : 10.1177/2047487318782379)

The associations between the response efficacy and objective and subjective change in physical activity and diet in the Information and Risk Modification trial.

Wou C, Silarova B, Griffin SJ, Usher-Smith JA

Public Health. Jun 2018

(DOI : 10.1016/j.puhe.2018.09.006)

Data visualisation to support obesity policy: case studies of data tools for planning and transport policy in the UK.

Monsivais P, Francis O, Lovelace R, Chang M, Strachan E, Burgoine T

International Journal of Obesity. Jun 2018

(DOI : 10.1038/s41366-018-0243-6)

Metabolomic and lipidomic plasma profile changes in human participants ascending to Everest Base Camp.

O'Brien KA, Atkinson RA, Richardson L, Koulman A, Murray AJ, Harridge SDR, Martin DS, Levett DZH, Mitchell K, Mythen MG, Montgomery HE, Grocott MPW, Griffin JL, Edwards LM

Scientific reports. Jun 2018

(DOI : 10.1038/s41598-019-38832-z)

Effect of Vitamin D Supplementation on Markers of Vascular Function: A Systematic Review and Individual Participant Meta-Analysis.

Beveridge LA, Khan F, Struthers AD, Armitage J, Barchetta I, Bressendorff I, Cavallo MG, Clarke R, Dalan R, Dreyer G, Gepner AD, Forouhi NG, Harris RA, Hitman GA, Larsen T, Khadgawat R, Marckmann P, Mose FH, Pilz S, Scholze A, Shargorodsky M, Sokol SI, Stricker H, Zoccali C, Witham MD

Journal of the American Heart Association. Jun 2018

(DOI : 10.1161/JAHA.117.008273)

Alcohol intake in relation to non-fatal and fatal coronary heart disease and stroke: EPIC-CVD case-cohort study.

Ricci C, Wood A, Muller D, Gunter MJ, Agudo A, Boeing H, van der Schouw YT, Warnakula S, Saieva C, Spijkerman A, Sluijs I, Tjønneland A, Kyrø C, Weiderpass E, Kühn T, Kaaks R, Sánchez MJ, Panico S, Agnoli C, Palli D, Tumino R, Engström G, Melander O, Bonnet F, Boer JMA, Key TJ, Travis RC, Overvad K, Verschuren WMM, Quirós JR, Trichopoulou A, Papatesta EM, Peppa E, Iribas CM, Gavrila D, Forslund AS, Jansson JH, Matullo G, Arriola L, Freisling H, Lassale C, Tzoulaki I, Sharp SJ, Forouhi NG, Langenberg C, Saracci R, Sweeting M, Brennan P, Butterworth AS, Riboli E, Wareham NJ, Danesh J, Ferrari P

BMJ (Clinical research ed.). May 2018

(DOI : 10.1136/bmj.k934)

One-carbon metabolism biomarkers and risk of urothelial cell carcinoma in the European prospective investigation into cancer and nutrition.

Bueno-de-Mesquita HB, Ros MM, Kampman E, Aben KK, Jansen EH, Roswall N, Tjønneland A, Boutron-Ruault MC, Cadeau C, Chang-Claude J, Kaaks R, Weikert S, Boeing H, Trichopoulou A, Lagiou P, Trichopoulos D, Sieri S, Palli D, Panico S, Peeters PH, Weiderpass E, Skeie G, Jakszyn P, Chirlaque MD, Ardanaz E, Sánchez MJ, Malm J, Ljungberg B, Khaw KT, Wareham NJ, Brennan P, Johansson M, Riboli E, Kiemeney LA

International journal of cancer. May 2018

(DOI : 10.1002/ijc.32165)

Association between genetic obesity susceptibility and mother-reported eating behaviour in children up to 5 years.

de Lauzon-Guillain B, Koudou YA, Botton J, Forhan A, Carles S, Pelloux V, Clément K, Ong KK, Charles MA, Heude B, EDEN Mother-Child Cohort Study Group

Pediatric Obesity. May 2018

(DOI : 10.1111/ijpo.12496)

Descriptive epidemiology of changes in objectively measured sedentary behaviour and physical activity: six-year follow-up of the EPIC-Norfolk cohort.

Hajna S, White T, Brage S, van Sluijs EMF, Westgate K, Jones AP, Luben R, Khaw KT, Wareham NJ, Griffin SJ

The international journal of behavioral nutrition and physical activity. May 2018

(DOI : 10.1186/s12966-018-0746-5)

Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches.

Wittemans LBL, Lotta LA, Langenberg C

Current diabetes reports. May 2018

(DOI : 10.1007/s11892-018-1009-1)

Circulating Phylloquinone Concentrations and Risk of Type 2 Diabetes: A Mendelian Randomization Study.

Zwakenberg SR, Remmelzwaal S, Beulens JWJ, Booth SL, Burgess S, Dashti HS, Imamura F, Feskens EJM, van der Schouw YT, Sluijs I

Diabetes. May 2018

(DOI : 10.2337/db18-0543)

Are consumption of dairy products and physical activity independently related to bone mineral density of 6-year-old children? Longitudinal and cross-sectional analyses in a birth cohort from Brazil.

Bielemann RM, Dos S Vaz J, Domingues MR, Matijasevich A, Santos IS, Ekelund U, Horta BL

Public Health Nutrition. May 2018

(DOI : 10.1017/S1368980018001258)

Diet quality and depressive symptoms in adolescence: no cross-sectional or prospective associations following adjustment for covariates.

Winpenny EM, van Harmelen AL, White M, Van Sluijs EM, Goodyer IM

Public Health Nutrition. May 2018

(DOI : 10.1017/S1368980018001179)

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Ligthart S, Vaez A, Võsa U, Stathopoulou MG, de Vries PS, Prins BP, van der Most PJ, Tanaka T, Naderi E, Rose LM, Wu Y, Karlsson R, Barbalic M, Lin H, Pool R, Zhu G, Macé A, Sidore C, Trompet S, Mangino M, Sabater-Lleal M, Kemp JP, Abbasi A, Kacprowski T, Verweij N, Smith AV, Huang T, Marzi C, Feitosa MF, Lohman KK, Kleber ME, Milaneschi Y, Mueller C, Huq M, Vlachopoulou E, Lyytikäinen LP, Oldmeadow C, Deelen J, Perola M, Zhao JH, Feenstra B, Lifelines Cohort Study, Amini M, CHARGE Inflammation Working Group, Lahti J, Schraut KE, Fornage M, Suktitipat B, Chen WM, Li X, Nutile T, Malerba G, Luan J, Bak T, Schork N, Del Greco M F, Thiering E, Mahajan A, Marioni RE, Mihailov E, Eriksson J, Ozel AB, Zhang W, Nethander M, Cheng YC, Aslibekyan S, Ang W, Gandin I, Yengo L, Portas L, Kooperberg C, Hofer E, Rajan KB, Schurmann C, den Hollander W, Ahluwalia TS, Zhao J, Draisma HHM, Ford I, Timpson N, Teumer A, Huang H, Wahl S, Liu Y, Huang J, Uh HW, Geller F, Joshi PK, Yanek LR, Trabetti E, Lehne B, Vozzi D, Verbanck M, Biino G, Saba Y, Meulenbelt I, O'Connell JR, Laakso M, Giulianini F, Magnusson PKE, Ballantyne CM, Hottenga JJ, Montgomery GW, Rivadineira F, Rueedi R, Steri M, Herzig KH, Stott DJ, Menni C, Frånberg M, St Pourcain B, Felix SB, Pers TH, Bakker SJL, Kraft P, Peters A, Vaidya D, Delgado G, Smit JH, Grossmann V, Sinisalo J, Seppala I, Williams SR, Holliday EG, Moed M, Langenberg C, Räikkönen K, Ding J, Campbell H, Sale MM, Chen YI, James AL, Ruggiero D, Soranzo N, Hartman CA, Smith EN, Berenson GS, Fuchsberger C, Hernandez D, Tiesler CMT, Giedraitis V, Liewald D, Fischer K, Mellström D, Larsson A, Wang Y, Scott WR, Lorentzon M, Beilby J, Ryan KA, Pennell CE, Vuckovic D, Balkau B, Concas MP, Schmidt R, Mendes de Leon CF, Bottinger EP, Kloppenburg M, Paternoster L, Boehnke M, Musk AW, Willemsen G, Evans DM, Madden PAF, Kähönen M, Kutalik Z, Zoledziewska M, Karhunen V, Kritchevsky SB, Sattar N, Lachance G, Clarke R, Harris TB, Raitakari OT, Attia JR, van Heemst D, Kajantie E, Sorice R, Gambaro G, Scott RA, Hicks AA, Ferrucci L, Standl M, Lindgren CM, Starr JM, Karlsson M, Lind L, Li JZ, Chambers JC, Mori TA, de Geus EJCN, Heath AC, Martin NG, Auvinen J, Buckley BM, de Craen AJM, Waldenberger M, Strauch K, Meitinger T, Scott RJ, McEvoy M, Beekman M, Bombieri C, Ridker PM, Mohlke KL, Pedersen NL, Morrison AC, Boomsma DI, Whitfield JB, Strachan DP, Hofman A, Vollenweider P, Cucca F, Järvelin MR, Jukema JW, Spector TD, Hamsten A, Zeller T, Uitterlinden AG, Nauck M, Gudnason V, Qi L, Grallert H, Borecki IB, Rotter JI, März W, Wild PS, Lokki ML, Boyle M, Salomaa V, Melbye M, Eriksson JG, Wilson JF, Penninx BWJH, Becker DM, Worrall BB, Gibson G, Krauss RM, Ciullo M, Zaza G, Wareham NJ, Oldehinkel AJ, Palmer LJ, Murray SS, Pramstaller PP, Bandinelli S, Heinrich J, Ingelsson E, Deary IJ, Mägi R, Vandenput L, van der Harst P, Desch KC, Kooner JS, Ohlsson C, Hayward C, Lehtimäki T, Shuldiner AR, Arnett DK, Beilin LJ, Robino A, Froguel P, Pirastu M, Jess T, Koenig W, Loos RJF, Evans DA, Schmidt H, Smith GD, Slagboom PE, Eiriksdottir G, Morris AP, Psaty BM, Tracy RP, Nolte IM, Boerwinkle E, Visvikis-Siest S, Reiner AP, Gross M, Bis JC, Franke L, Franco OH, Benjamin EJ, Chasman DI, Dupuis J, Snieder H, Dehghan A, Alizadeh BZ

American journal of human genetics. May 2018

(DOI : 10.1016/j.ajhg.2018.09.009)

Characteristics of the environment and physical activity in midlife: Findings from UK Biobank.

Smith L, Panter J, Ogilvie D

Preventive Medicine . May 2018

(DOI : 10.1016/j.ypmed.2018.10.024)

Changes in workplace car parking and commute mode: a natural experimental study.

Knott CS, Sharp SJ, Mytton OT, Ogilvie D, Panter J

Journal of Epidemiology and Community Health. May 2018

(DOI : 10.1136/jech-2018-210983)

Retinal Vasculometry Associations with Cardiometabolic Risk Factors in the European Prospective Investigation of Cancer-Norfolk Study.

Owen CG, Rudnicka AR, Welikala RA, Fraz MM, Barman SA, Luben R, Hayat SA, Khaw KT, Strachan DP, Whincup PH, Foster PJ

Ophthalmology. May 2018

(DOI : 10.1016/j.ophtha.2018.07.022)

Is vigorous-intensity physical activity required for improving bone mass in adolescence? Findings from a Brazilian birth cohort.

Bielemann RM, Ramires VV, Wehrmeister FC, Gonçalves H, Assunção MCF, Ekelund U, Horta BL

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. May 2018

(DOI : 10.1007/s00198-019-04862-6)

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.

Erzurumluoglu AM, Barnes DR, Melbourne CA, Young R, Batini C, Surendran P, Jiang T, Afaq S, Agrawal A, Altmaier E, Antoniou AC, Asselbergs FW, Baumbach C, Bierut L, Bertelsen S, Boehnke M, Bots ML, Brazel DM, Chambers JC, Chang-Claude J, Chen C, Corley J, Chou YL, David SP, de Boer RA, de Leeuw CA, Dennis JG, Dominiczak AF, Dunning AM, Easton DF, Elliott P, Evangelou E, Faul JD, Foroud T, Goate A, Gong J, Grabe HJ, Haessler J, Haiman C, Hallmans G, Hammerschlag AR, Harris SE, Hattersley A, Heath A, Iacono WG, Kanoni S, Kapoor M, Kaprio J, Kardia SL, Karpe F, Kontto J, Kooner JS, Kooperberg C, Kuulasmaa K, Laakso M, Langenberg C, Lettre G, Loukola A, Luan J, Madden PAF, Mangino M, Marioni RE, Marouli E, Marten J, Martin NG, McGue M, Michailidou K, Mihailov E, Moayyeri A, Moitry M, Müller-Nurasyid M, Nauck M, Neville MJ, Nielsen SF, North K, Perola M, Pharoah PDP, Pistis G, Polderman TJ, Posthuma D, Poulter N, Qaiser B, Rasheed A, Reiner A, Renstrom F, Rice J, Rohde R, Rolandsson O, Samani NJ, Samuel M, Schlessinger D, Scott RA, Sever P, Shao Y, Shrine N, Smith JA, Starr JM, Stirrups K, Stram D, Stringham HM, Tachmazidou I, Tardif JC, Thompson DJ, Tindle HA, Tragante V, Trompet S, Turcot V, Tyrrell J, Van Der Leij AR, van der Meer P, Varga TV, Verweij N, Völzke H, Wareham NJ, Warren HR, Weir DR, Weiss S, Wetherill L, Yaghootkar H, Jiang Y, Zhan X, Zhang W, Zhao W, Zhao W, Amouyel P, Blankenberg S, Caulfield MJ, Chowdhury R, Cucca F, Deary IJ, Deloukas P, Di Angelantonio E, Ferrario M, Ferrières J, Franks PW, Frayling TM, Frossard P, Hall IP, Hayward C, Jansson JH, Jukema JW, Männistö S, Metspalu A, Munroe PB, Nordestgaard BG, Palmer CNA, Salomaa V, Sattar N, Spector T, Strachan DP, van der Harst P, Zeggini E, Saleheen D, Butterworth AS, Wain LV, Abecasis GR, Danesh J, Tobin MD, Vrieze S, Liu DJ, Howson JMM

Molecular psychiatry. May 2018

(DOI : 10.1038/s41380-018-0313-0)

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.

Day F, Karaderi T, Jones MR, Meun C, He C, Drong A, Kraft P, Lin N, Huang H, Broer L, Mägi R, Saxena R, Laisk T, Urbanek M, Hayes MG, Thorleifsson G, Fernandez-Tajes J, Mahajan A, Mullin BH, Stuckey BGA, Spector TD, Wilson SG, Goodarzi MO, Davis L, Obermayer-Pietsch B, Uitterlinden AG, Anttila V, Neale BM, Järvelin MR, Fauser B, Kowalska I, Visser JA, Andersen M, Ong K, Stener-Victorin E, Ehrmann D, Legro RS, Salumets A, McCarthy MI, Morin-Papunen L, Thorsteinsdottir U, Stefansson K, 23andMe Research Team, Styrkarsdottir U, Perry JRB, Dunaif A, Laven J, Franks S, Lindgren CM, Welt CK

PLoS genetics. Apr 2018

(DOI : 10.1371/journal.pgen.1007813)

Sodium and potassium excretion in an adult Caribbean population of African descent with a high burden of cardiovascular disease.

Harris RM, Rose AMC, Hambleton IR, Howitt C, Forouhi NG, Hennis AJM, Samuels TA, Unwin N

BMC Public Health. Apr 2018

(DOI : 10.1186/s12889-018-5694-0)

A strong sense of coherence associated with reduced risk of anxiety disorder among women in disadvantaged circumstances: British population study.

Remes O, Wainwright NWJ, Surtees P, Lafortune L, Khaw KT, Brayne C

BMJ Open. Apr 2018

(DOI : 10.1136/bmjopen-2017-018501)

Haem iron intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

Ward HA, Whitman J, Muller DC, Johansson M, Jakszyn P, Weiderpass E, Palli D, Fanidi A, Vermeulen R, Tjønneland A, Hansen L, Dahm CC, Overvad K, Severi G, Boutron-Ruault MC, Affret A, Kaaks R, Fortner R, Boeing H, Trichopoulou A, La Vecchia C, Kotanidou A, Berrino F, Krogh V, Tumino R, Ricceri F, Panico S, Bueno-de-Mesquita HB, Peeters PH, Nøst TH, Sandanger TM, Quirós JR, Agudo A, Rodriguez-Barranco M, Larrañaga N, Huerta JM, Ardanaz E, Drake I, Brunnström H, Grankvist K, Travis RC, Freisling H, Stepien M, Merritt MA, Riboli E, Cross AJ

European Journal of Clinical Nutrition. Apr 2018

(DOI : PMC6372073)

Coffee and Tea Consumption and the Contribution of Their Added Ingredients to Total Energy and Nutrient Intakes in 10 European Countries: Benchmark Data from the Late 1990s.

Landais E, Moskal A, Mullee A, Nicolas G, Gunter MJ, Huybrechts I, Overvad K, Roswall N, Affret A, Fagherazzi G, Mahamat-Saleh Y, Katzke V, Kühn T, La Vecchia C, Trichopoulou A, Valanou E, Saieva C, Santucci De Magistris M, Sieri S, Braaten T, Skeie G, Weiderpass E, Ardanaz E, Chirlaque MD, Garcia JR, Jakszyn P, Rodriguez-Barranco M, Brunkwall L, Huseinovic E, Nilsson L, Wallström P, Bueno-de-Mesquita B, Peeters PH, Aune D, Key T, Lentjes M, Riboli E, Slimani N, Freisling H

Nutrients. Apr 2018

(DOI : 10.3390/nu10060725)

Evaluating policy responses to noncommunicable diseases in seven Caribbean countries: challenges to addressing unhealthy diets and physical inactivity.

Murphy MM, Unwin N, Samuels TA, Hassel TA, Bishop L, Guell C

Revista panamericana de salud publica = Pan American journal of public health. Apr 2018

(DOI : 10.26633/RPSP.2018.174)

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

Giri A, Hellwege JN, Warren HR, Kovesdy CP, Sun YV, Robinson-Cohen C, Damrauer SM, Klarin D, Wang Y, Evangelou E, Cabrera CP, Wain LV, Sargurupremraj M, Debette S, Boehnke M, Scott LJ, Luan J, Zhao JH, Willems S, Thériault S, Shah N, Oldmeadow C, Almgren P, Li-Gao R, Verweij N, Boutin TS, Mangino M, Ntalla I, Surendran P, Cook JP, Karthikeyan S, Amouyel P, Farrall M, Poulter NR, Laakso M, Zeggini E, Sever P, Scott RA, Langenberg C, Wareham NJ, Conen D, Palmer CNA, Attia J, Chasman DI, Ridker PM, Melander O, Mook-Kanamori DO, Cucca F, Schlessinger D, Hayward C, Spector TD, Järvelin MR, Hennig BJ, Timpson NJ, Lindgren C, Herzig KH, Dedoussis G, Denny JC, Psaty BM, Howson JMM, Munroe PB, Newton-Cheh C, Caulfield MJ, Elliott P, Gaziano JM, Wilson PWF, Tsao PS, Velez Edwards DR, Susztak K, O'Donnell CJ, Hung AM, Edwards TL

Nature genetics. Apr 2018

(DOI : 10.1038/s41588-018-0303-9)

Social determinants of prostate cancer in the Caribbean: a systematic review and meta-analysis.

Brown CR, Hambleton I, Hercules SM, Unwin N, Murphy MM, Nigel Harris E, Wilks R, MacLeish M, Sullivan L, Sobers-Grannum N, U.S. Caribbean Alliance for Health Disparities Research Group (USCAHDR)

BMC Public Health. Apr 2018

(DOI : 10.1186/s12889-018-5696-y)

Fatty acid biomarkers of dairy fat consumption and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.

Imamura F, Fretts A, Marklund M, Ardisson Korat AV, Yang WS, Lankinen M, Qureshi W, Helmer C, Chen TA, Wong K, Bassett JK, Murphy R, Tintle N, Yu CI, Brouwer IA, Chien KL, Frazier-Wood AC, Del Gobbo LC, Djoussé L, Geleijnse JM, Giles GG, de Goede J, Gudnason V, Harris WS, Hodge A, Hu F, InterAct Consortium, Koulman A, Laakso M, Lind L, Lin HJ, McKnight B, Rajaobelina K, Riserus U, Robinson JG, Samieri C, Siscovick DS, Soedamah-Muthu SS, Sotoodehnia N, Sun Q, Tsai MY, Uusitupa M, Wagenknecht LE, Wareham NJ, Wu JH, Micha R, Forouhi NG, Lemaitre RN, Mozaffarian D, Fatty Acids and Outcomes Research Consortium (FORCE)

PLoS Medicine. Apr 2018

(DOI : 10.1371/journal.pmed.1002670)

Metformin in non-diabetic hyperglycaemia: the GLINT feasibility RCT.

Griffin SJ, Bethel MA, Holman RR, Khunti K, Wareham N, Brierley G, Davies M, Dymond A, Eichenberger R, Evans P, Gray A, Greaves C, Harrington K, Hitman G, Irving G, Lessels S, Millward A, Petrie JR, Rutter M, Sampson M, Sattar N, Sharp S

Health technology assessment (Winchester, England). Apr 2018

(DOI : 10.3310/hta22180)

Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study.

Deschasaux M, Huybrechts I, Murphy N, Julia C, Hercberg S, Srour B, Kesse-Guyot E, Latino-Martel P, Biessy C, Casagrande C, Jenab M, Ward H, Weiderpass E, Dahm CC, Overvad K, Kyrø C, Olsen A, Affret A, Boutron-Ruault MC, Mahamat-Saleh Y, Kaaks R, Kühn T, Boeing H, Schwingshackl L, Bamia C, Peppa E, Trichopoulou A, Masala G, Krogh V, Panico S, Tumino R, Sacerdote C, Bueno-de-Mesquita B, Peeters PH, Hjartåker A, Rylander C, Skeie G, Ramón Quirós J, Jakszyn P, Salamanca-Fernández E, Huerta JM, Ardanaz E, Amiano P, Ericson U, Sonestedt E, Huseinovic E, Johansson I, Khaw KT, Wareham N, Bradbury KE, Perez-Cornago A, Tsilidis KK, Ferrari P, Riboli E, Gunter MJ, Touvier M

PLoS Medicine. Apr 2018

(DOI : 10.1371/journal.pmed.1002651)

Sociodemographic characteristics and frequency of consuming home-cooked meals and meals from out-of-home sources: cross-sectional analysis of a population-based cohort study.

Mills S, Adams J, Wrieden W, White M, Brown H

Public Health Nutrition. Apr 2018

(DOI : 10.1017/S1368980018000812)

Does domiciliary welfare rights advice improve health-related quality of life in independent-living, socio-economically disadvantaged people aged ≥60 years? Randomised controlled trial, economic and process evaluations in the North East of England.

Howel D, Moffatt S, Haighton C, Bryant A, Becker F, Steer M, Lawson S, Aspray T, Milne EMG, Vale L, McColl E, White M

PLoS ONE. Apr 2018

(DOI : 10.1371/journal.pone.0209560)

Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies.

Do KT, Wahl S, Raffler J, Molnos S, Laimighofer M, Adamski J, Suhre K, Strauch K, Peters A, Gieger C, Langenberg C, Stewart ID, Theis FJ, Grallert H, Kastenmüller G, Krumsiek J

Metabolomics : Official journal of the Metabolomic Society. Apr 2018

(DOI : 10.1007/s11306-018-1420-2)

Thyroid Dysfunction and Anemia: A Prospective Cohort Study and a Systematic Review.

Floriani C, Feller M, Aubert CE, M'Rabet-Bensalah K, Collet TH, den Elzen WPJ, Bauer DC, Angelillo-Scherrer A, Aujesky D, Rodondi N

Thyroid : official journal of the American Thyroid Association. Apr 2018

(DOI : 10.1089/thy.2017.0480)

Low Free Testosterone and Prostate Cancer Risk: A Collaborative Analysis of 20 Prospective Studies.

Watts EL, Appleby PN, Perez-Cornago A, Bueno-de-Mesquita HB, Chan JM, Chen C, Cohn BA, Cook MB, Flicker L, Freedman ND, Giles GG, Giovannucci E, Gislefoss RE, Hankey GJ, Kaaks R, Knekt P, Kolonel LN, Kubo T, Le Marchand L, Luben RN, Luostarinen T, Männistö S, Metter EJ, Mikami K, Milne RL, Ozasa K, Platz EA, Quirós JR, Rissanen H, Sawada N, Stampfer M, Stanczyk FZ, Stattin P, Tamakoshi A, Tangen CM, Thompson IM, Tsilidis KK, Tsugane S, Ursin G, Vatten L, Weiss NS, Yeap BB, Allen NE, Key TJ, Travis RC

European urology. Apr 2018

(DOI : 10.1016/j.eururo.2018.07.024)

Development and Validation of Lifestyle-Based Models to Predict Incidence of the Most Common Potentially Preventable Cancers.

Usher-Smith JA, Sharp SJ, Luben R, Griffin SJ

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Apr 2018

(DOI : 10.1158/1055-9965.EPI-18-0400)

Validity of ultrasonography to assess hepatic steatosis compared to magnetic resonance spectroscopy as a criterion method in older adults.

De Lucia Rolfe E, Brage S, Sleigh A, Finucane F, Griffin SJ, Wareham NJ, Ong KK, Forouhi NG

PLoS ONE. Apr 2018

(DOI : 10.1371/journal.pone.0207923)

The role of physical activity in the development of first cardiovascular disease event: a tree-structured survival analysis of the Danish ADDITION-PRO cohort.

Amadid H, Johansen NB, Bjerregaard AL, Brage S, Færch K, Lauritzen T, Witte DR, Sandbæk A, Jørgensen ME, Vistisen D

Cardiovascular diabetology. Apr 2018

(DOI : 10.1186/s12933-018-0769-x)

Cross-Sectional Associations of Reallocating Time Between Sedentary and Active Behaviours on Cardiometabolic Risk Factors in Young People: An International Children's Accelerometry Database (ICAD) Analysis.

Hansen BH, Anderssen SA, Andersen LB, Hildebrand M, Kolle E, Steene-Johannessen J, Kriemler S, Page AS, Puder JJ, Reilly JJ, Sardinha LB, van Sluijs EMF, Wedderkopp N, Ekelund U, International Childrens Accelerometry Database (ICAD) Collaborators