MRC Epidemiology Unit

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There are 4427 publications in the database

Likely causal effects of insulin resistance and IGF-1 bioaction on childhood and adult adiposity: a Mendelian randomization study.

Olwi DI, Kaisinger LR, Kentistou KA, Vaudel M, Stankovic S, Njølstad PR, Johansson S, Perry JRB, Day FR, Ong KK

International journal of obesity (2005). Aug 2024

(DOI : 10.1038/s41366-024-01605-4)

Meat consumption and incident type 2 diabetes: an individual-participant federated meta-analysis of 1·97 million adults with 100 000 incident cases from 31 cohorts in 20 countries.

Li C, Bishop TRP, Imamura F, Sharp SJ, Pearce M, Brage S, Ong KK, Ahsan H, Bes-Rastrollo M, Beulens JWJ, den Braver N, Byberg L, Canhada S, Chen Z, Chung HF, Cortes-Valencia A, Djoussé L, Drouin-Chartier JP, Du H, Du S, Duncan BB, Gaziano JM, Gordon-Larsen P, Goto A, Haghighatdoost F, Härkänen T, Hashemian M, Hu FB, Ittermann T, Järvinen R, Kakkoura MG, Neelakantan N, Knekt P, Lajous M, Li Y, Magliano DJ, Malekzadeh R, Le Marchand L, Marques-Vidal P, Martínez-González MÁ, Maskarinec G, Mishra GD, Mohammadifard N, O'Donoghue G, O'Gorman D, Popkin B, Poustchi H, Sarrafzadegan N, Sawada N, Schmidt MI, Shaw JE, Soedamah-Muthu S, Stern D, Tong L, van Dam RM, Völzke H, Willett WC, Wolk A, Yu C, EPIC-InterAct Consortium EPIC-InterAct Consortium, Forouhi NG, Wareham NJ

The lancet. Diabetes & endocrinology. Aug 2024

(DOI : 10.1016/S2213-8587(24)00179-7)

Disaggregation of Dairy in Composite Foods in the United Kingdom.

Jaacks LM, Amoutzopoulos B, Runions R, Vonderschmidt A, McNeill G, Comrie F, McDonald A, Page P, Stewart C

Current developments in nutrition. Aug 2024

(DOI : 10.1016/j.cdnut.2024.103774)

School-level intra-cluster correlation coefficients and autocorrelations for children's accelerometer-measured physical activity in England by age and gender.

Salway R, Jago R, de Vocht F, House D, Porter A, Walker R, Kipping R, Owen CG, Hudda MT, Northstone K, van Sluijs E, International Children’s Accelerometry Database (ICAD) Collaborators International Children’s Accelerometry Database (ICAD) Collaborators

BMC Medical Research Methodology. Aug 2024

(DOI : 10.1186/s12874-024-02290-7)

Trends in hospitalization for cardio-renal disease and mortality in people with type 1 diabetes in England, 2009-2019.

Holman N, Young B, Gregg EW, Wareham N, Sharp S, Khunti K, Sattar N, Valabhji J

Diabetes, obesity & metabolism. Aug 2024

(DOI : 10.1111/dom.15783)

The effect of an acute bout of exercise on circulating vitamin D metabolite concentrations: a randomised crossover study in healthy adults.

Davies SE, Perkin OJ, Betts JA, Gonzalez JT, Hewison M, Jenkinson C, Jones KS, Meadows SR, Parkington DA, Koulman A, Thompson D

The Journal of physiology. Aug 2024

(DOI : 10.1113/JP286395)

Digital Intervention Promoting Physical Activity in People Newly Diagnosed with Parkinson's Disease: Feasibility and Acceptability of the Knowledge, Exercise-Efficacy and Participation (KEEP) Intervention.

Agley L, Hartley P, Duffill D, Iqbal A, Mackett A, Rennie KL, Lafortune L

Journal of Parkinson's disease. Aug 2024

(DOI : 10.3233/JPD-240071)

The role of metaphor in the corporate political strategies of health harming industries: Comparing the concept of balance in the gambling and opioid industry discourses.

van Schalkwyk MC, Hawkins B, Eisenkraft Klein D, Koon AD

Social science & medicine (1982). Aug 2024

(DOI : 10.1016/j.socscimed.2024.117158)

Physical activity volume, intensity, and mortality: Harmonized meta-analysis of prospective cohort studies.

Tarp J, Dalene KE, Fagerland MW, Steene-Johannesen J, Hansen BH, Anderssen SA, Hagströmer M, Dohrn IM, Dempsey PC, Wijndaele K, Brage S, Nordström A, Nordström P, Diaz KM, Howard VJ, Hooker SP, Morseth B, Hopstock LA, Sagelv EH, Yates T, Edwardson CL, Lee IM, Ekelund U

American Journal of Preventive Medicine. Aug 2024

(DOI : 10.1016/j.amepre.2024.07.022)

Modifiable lifestyle factors and the risk of post-COVID-19 multisystem sequelae, hospitalization, and death.

Wang Y, Su B, Alcalde-Herraiz M, Barclay NL, Tian Y, Li C, Wareham NJ, Paredes R, Xie J, Prieto-Alhambra D

Nature communications. Jul 2024

(DOI : 10.1038/s41467-024-50495-7)

Cross-sectional associations of gender identity and sexual orientation, with co-occurrence and clustering of health-related behaviours among British adolescents: Millennium cohort study.

Ricardo LIC, Smith AD, Hesketh KR, Chavez-Ugalde Y, Lee EY, van Sluijs EMF

Preventive medicine. Jul 2024

(DOI : 10.1016/j.ypmed.2024.108084)

Proteomic signatures improve risk prediction for common and rare diseases.

Carrasco-Zanini J, Pietzner M, Davitte J, Surendran P, Croteau-Chonka DC, Robins C, Torralbo A, Tomlinson C, Grünschläger F, Fitzpatrick N, Ytsma C, Kanno T, Gade S, Freitag D, Ziebell F, Haas S, Denaxas S, Betts JC, Wareham NJ, Hemingway H, Scott RA, Langenberg C

Nature medicine. Jul 2024

(DOI : 10.1038/s41591-024-03142-z)

Ultra-processed food consumption in UK adolescents: distribution, trends, and sociodemographic correlates using the National Diet and Nutrition Survey 2008/09 to 2018/19.

Chavez-Ugalde IY, de Vocht F, Jago R, Adams J, Ong KK, Forouhi NG, Colombet Z, Ricardo LIC, van Sluijs E, Toumpakari Z

European journal of nutrition. Jul 2024

(DOI : 10.1007/s00394-024-03458-z)

An app promoting weight gain prevention via healthy behaviours amongst young women with a family history of breast cancer: Acceptability and usability assessment.

Pegington M, Hawkes RE, Davies A, Mueller J, Howell A, Gareth Evans D, Howell SJ, French DP, Harvie M

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association. Jul 2024

(DOI : 10.1111/jhn.13347)

The Impact of Delayed Processing of Chilled Whole Blood Specimens on the Measurement of Nutritional Biomarkers in the United Kingdom National Diet and Nutrition Survey Rolling Programme.

Jones KS, Meadows SR, Parkington DA, Collins D, Bates B, Koulman A, Page P

The Journal of nutrition. Jul 2024

(DOI : 10.1016/j.tjnut.2024.07.008)

Screen Media Use and Mental Health of Children and Adolescents: A Secondary Analysis of a Randomized Clinical Trial.

Schmidt-Persson J, Rasmussen MGB, Sørensen SO, Mortensen SR, Olesen LG, Brage S, Kristensen PL, Bilenberg N, Grøntved A

JAMA network open. Jul 2024

(DOI : 10.1001/jamanetworkopen.2024.19881)

Estimated changes in free sugar consumption one year after the UK soft drinks industry levy came into force: controlled interrupted time series analysis of the National Diet and Nutrition Survey (2011-2019).

Rogers NT, Cummins S, Jones CP, Mytton O, Rayner M, Rutter H, White M, Adams J

Journal of Epidemiology and Community Health. Jul 2024

(DOI : 10.1136/jech-2023-221051)

Public transport use and mortality among older adults in England: A cohort study.

Patterson R, de Oliveira C, Schneider IJC, Mindell JS, Panter J, Laverty AA

Preventive medicine. Jul 2024

(DOI : 10.1016/j.ypmed.2024.108064)

Complex patterns of multimorbidity associated with severe COVID-19 and long COVID.

Pietzner M, Denaxas S, Yasmeen S, Ulmer MA, Nakanishi T, Arnold M, Kastenmüller G, Hemingway H, Langenberg C

Communications medicine. Jul 2024

(DOI : 10.1038/s43856-024-00506-x)

Assessment of Erythrocyte Transketolase, Whole Blood Thiamine Diphosphate, and Human Milk Thiamine Concentrations to Identify Infants and Young Children Responding Favorably to Therapeutic Thiamine Administration: Findings from the Lao Thiamine Study, a Prospective Cohort Study.

Hess SY, Smith TJ, Arnold CD, Jones KS, Hampel D, Hiffler L, Trehan I, Fischer PR, Meadows SR, Parkington DA, Brown KH, Sitthideth D, Tan X, Koulman A, Allen LH, Kounnavong S

Current developments in nutrition. Jul 2024

(DOI : 10.1016/j.cdnut.2024.103786)

Loss of transient receptor potential channel 5 causes obesity and postpartum depression.

Li Y, Cacciottolo TM, Yin N, He Y, Liu H, Yang Y, Henning E, Keogh JM, Lawler K, Mendes de Oliveira E, Gardner EJ, Kentistou KA, Laouris P, Bounds R, Ong KK, Perry JRB, Barroso I, Tu L, Bean JC, Yu M, Conde KM, Wang M, Ginnard O, Fang X, Tong L, Han J, Darwich T, Williams KW, Wang C, Joss S, Firth HV, Xu Y, Farooqi IS

Cell. Jul 2024

(DOI : 10.1016/j.cell.2024.06.001)

Developing inclusive public involvement and engagement activities with secondary school students and educational professionals: a protocol.

Cross L, Banham D, Melendez-Torres GJ, Ford T, van Sluijs E, Liabo K

Research involvement and engagement. Jul 2024

(DOI : 10.1186/s40900-024-00581-3)

Understanding the genetic complexity of puberty timing across the allele frequency spectrum.

Kentistou KA, Kaisinger LR, Stankovic S, Vaudel M, Mendes de Oliveira E, Messina A, Walters RG, Liu X, Busch AS, Helgason H, Thompson DJ, Santoni F, Petricek KM, Zouaghi Y, Huang-Doran I, Gudbjartsson DF, Bratland E, Lin K, Gardner EJ, Zhao Y, Jia RY, Terao C, Riggan MJ, Bolla MK, Yazdanpanah M, Yazdanpanah N, Bradfield JP, Broer L, Campbell A, Chasman DI, Cousminer DL, Franceschini N, Franke LH, Girotto G, He C, Järvelin MR, Joshi PK, Kamatani Y, Karlsson R, Luan J, Lunetta KL, Mägi R, Mangino M, Medland SE, Meisinger C, Noordam R, Nutile T, Concas MP, Polasek O, Porcu E, Ring SM, Sala C, Smith AV, Tanaka T, van der Most PJ, Vitart V, Wang CA, Willemsen G, Zygmunt M, Ahearn TU, Andrulis IL, Anton-Culver H, Antoniou AC, Auer PL, Barnes CLK, Beckmann MW, Berrington de González A, Bogdanova NV, Bojesen SE, Brenner H, Buring JE, Canzian F, Chang-Claude J, Couch FJ, Cox A, Crisponi L, Czene K, Daly MB, Demerath EW, Dennis J, Devilee P, De Vivo I, Dörk T, Dunning AM, Dwek M, Eriksson JG, Fasching PA, Fernández-Rhodes L, Ferreli L, Fletcher O, Gago-Dominguez M, García-Closas M, García-Sáenz JA, González-Neira A, Grallert H, Guénel P, Haiman CA, Hall P, Hamann U, Hakonarson H, Hart RJ, Hickey M, Hooning MJ, Hoppe R, Hopper JL, Hottenga JJ, Hu FB, Huebner H, Hunter DJ, ABCTB Investigators ABCTB Investigators, Jernström H, John EM, Karasik D, Khusnutdinova EK, Kristensen VN, Lacey JV, Lambrechts D, Launer LJ, Lind PA, Lindblom A, Magnusson PKE, Mannermaa A, McCarthy MI, Meitinger T, Menni C, Michailidou K, Millwood IY, Milne RL, Montgomery GW, Nevanlinna H, Nolte IM, Nyholt DR, Obi N, O'Brien KM, Offit K, Oldehinkel AJ, Ostrowski SR, Palotie A, Pedersen OB, Peters A, Pianigiani G, Plaseska-Karanfilska D, Pouta A, Pozarickij A, Radice P, Rennert G, Rosendaal FR, Ruggiero D, Saloustros E, Sandler DP, Schipf S, Schmidt CO, Schmidt MK, Small K, Spedicati B, Stampfer M, Stone J, Tamimi RM, Teras LR, Tikkanen E, Turman C, Vachon CM, Wang Q, Winqvist R, Wolk A, Zemel BS, Zheng W, van Dijk KW, Alizadeh BZ, Bandinelli S, Boerwinkle E, Boomsma DI, Ciullo M, Chenevix-Trench G, Cucca F, Esko T, Gieger C, Grant SFA, Gudnason V, Hayward C, Kolcic I, Kraft P, Lawlor DA, Martin NG, Nøhr EA, Pedersen NL, Pennell CE, Ridker PM, Robino A, Snieder H, Sovio U, Spector TD, Stöckl D, Sudlow C, Timpson NJ, Toniolo D, Uitterlinden A, Ulivi S, Völzke H, Wareham NJ, Widén E, Wilson JF, Lifelines Cohort Study Lifelines Cohort Study, Danish Blood Donor Study Danish Blood Donor Study, Ovarian Cancer Association Consortium Ovarian Cancer Association Consortium, Breast Cancer Association Consortium Breast Cancer Association Consortium, Biobank Japan Project Biobank Japan Project, China Kadoorie Biobank Collaborative Group China Kadoorie Biobank Collaborative Group, Pharoah PDP, Li L, Easton DF, Njølstad PR, Sulem P, Murabito JM, Murray A, Manousaki D, Juul A, Erikstrup C, Stefansson K, Horikoshi M, Chen Z, Farooqi IS, Pitteloud N, Johansson S, Day FR, Perry JRB, Ong KK

Nature genetics. Jul 2024

(DOI : 10.1038/s41588-024-01798-4)

Proteomic prediction of diverse incident diseases: a machine learning-guided biomarker discovery study using data from a prospective cohort study.

Carrasco-Zanini J, Pietzner M, Koprulu M, Wheeler E, Kerrison ND, Wareham NJ, Langenberg C

The Lancet. Digital health. Jun 2024

(DOI : 10.1016/S2589-7500(24)00087-6)

Identifying proteomic risk factors for overall, aggressive, and early onset prostate cancer using Mendelian Randomisation and tumour spatial transcriptomics.

Desai TA, Hedman ÅK, Dimitriou M, Koprulu M, Figiel S, Yin W, Johansson M, Watts EL, Atkins JR, Sokolov AV, Schioth HB, Gunter MJ, Tsilidis KK, Martin RM, Pietzner M, Langenberg C, Mills IG, Lamb AD, Malarstig A, Key TJ, PRACTICAL Consortium PRACTICAL Consortium, Travis RC, Smith-Byrne K

EBioMedicine. Jun 2024

(DOI : 10.1016/j.ebiom.2024.105168)

Resilience of mental health services amidst Ebola disease outbreaks in Africa.

Wirsiy FS, Tahmo NB, Tatah L, Brett-Major DM

Frontiers in Public Health. Jun 2024

(DOI : 10.3389/fpubh.2024.1369306)

A predictive model for medium-term weight loss response in people with type 2 diabetes engaging in behavioural weight management interventions.

Al-Abdullah L, Ahern A, Welsh P, Logue J

Diabetes, obesity & metabolism. Jun 2024

(DOI : 10.1111/dom.15706)

Genetic drivers and cellular selection of female mosaic X chromosome loss.

Liu A, Genovese G, Zhao Y, Pirinen M, Zekavat SM, Kentistou KA, Yang Z, Yu K, Vlasschaert C, Liu X, Brown DW, Hudjashov G, Gorman BR, Dennis J, Zhou W, Momozawa Y, Pyarajan S, Tuzov V, Pajuste FD, Aavikko M, Sipilä TP, Ghazal A, Huang WY, Freedman ND, Song L, Gardner EJ, FinnGen FinnGen, Estonian Biobank Research Team Estonian Biobank Research Team, Breast Cancer Association Consortium Breast Cancer Association Consortium, Million Veteran Program Million Veteran Program, Sankaran VG, Palotie A, Ollila HM, Tukiainen T, Chanock SJ, Mägi R, Natarajan P, Daly MJ, Bick A, McCarroll SA, Terao C, Loh PR, Ganna A, Perry JRB, Machiela MJ

Nature. Jun 2024

(DOI : 10.1038/s41586-024-07533-7)

The UK Soft Drinks Industry Levy and childhood hospital admissions for asthma in England.

Rogers NT, Cummins S, Jones CP, Mytton OT, Roberts CH, Shaheen SO, Shah SA, Sheikh A, White M, Adams J

Nature communications. Jun 2024

(DOI : 10.1038/s41467-024-49120-4)

A systematic evaluation of seven different scores representing the EAT-Lancet reference diet and mortality, stroke, and greenhouse gas emissions in three cohorts.

Stubbendorff A, Stern D, Ericson U, Sonestedt E, Hallström E, Borné Y, Lajous M, Forouhi NG, Olsen A, Dahm CC, Ibsen DB

The Lancet. Planetary health. Jun 2024

(DOI : 10.1016/S2542-5196(24)00094-9)

Protocol for a seamless phase 2A-phase 2B randomized double-blind placebo-controlled trial to evaluate the safety and efficacy of benfotiamine in patients with early Alzheimer's disease (BenfoTeam).

Feldman HH, Luchsinger JA, Léger GC, Taylor C, Jacobs DM, Salmon DP, Edland SD, Messer K, Revta C, Flowers SA, Jones KS, Koulman A, Yarasheski KE, Verghese PB, Venkatesh V, Zetterberg H, Durant J, Lupo JL, Gibson GE, ADCS BenfoTeam Study Group ADCS BenfoTeam Study Group

PLoS ONE. May 2024

(DOI : 10.1371/journal.pone.0302998)

Metabolome-wide Mendelian randomization for age at menarche and age at natural menopause.

Yazdanpanah M, Yazdanpanah N, Gamache I, Ong K, Perry JRB, Manousaki D

Genome medicine. May 2024

(DOI : 10.1186/s13073-024-01322-7)

Associations of Systematic Inflammatory Markers with Diet Quality, Blood Pressure, and Obesity in the AIRWAVE Health Monitoring Study.

Aljuraiban GS, Gibson R, Oude Griep LM

Journal of inflammation research. May 2024

(DOI : 10.2147/JIR.S459238)

Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats.

Steinfeldt J, Wild B, Buergel T, Pietzner M, Upmeier Zu Belzen J, Vauvelle A, Hegselmann S, Denaxas S, Hemingway H, Langenberg C, Landmesser U, Deanfield J, Eils R

Nature communications. May 2024

(DOI : 10.1038/s41467-024-48568-8)

Sugar-Sweetened Beverage Consumption and Height Loss in Adults: A Longitudinal Analysis in the EPIC-Norfolk Study.

Lee JY, Imamura F

The Journal of nutrition. May 2024

(DOI : 10.1016/j.tjnut.2024.05.007)

Relationship between HLA genetic variations, COVID-19 vaccine antibody response, and risk of breakthrough outcomes.

Xie J, Mothe B, Alcalde Herraiz M, Li C, Xu Y, Jödicke AM, Gao Y, Wang Y, Feng S, Wei J, Chen Z, Hong S, Wu Y, Su B, Zheng X, Cohet C, Ali R, Wareham N, Alhambra DP

Nature communications. May 2024

(DOI : 10.1038/s41467-024-48339-5)

Assessing Performance of Contemporary Plant-Based Diets against the UK Dietary Guidelines: Findings from the Feeding the Future (FEED) Study.

Lawson I, Wood C, Syam N, Rippin H, Dagless S, Wickramasinghe K, Amoutzopoulos B, Steer T, Key TJ, Papier K

Nutrients. May 2024

(DOI : 10.3390/nu16091336)

Exploring the changing association between parental and adolescent fruit and vegetable intakes, from age 10 to 30 years.

Braune T, Adams J, Winpenny EM

The international journal of behavioral nutrition and physical activity. May 2024

(DOI : 10.1186/s12966-024-01604-8)

Prediabetes, participation in the English National Health Service Diabetes Prevention Programme, and associations with COVID-19-related mortality: A whole population study.

Barron E, Sharp SJ, Khunti K, Bakhai C, Wareham NJ, Valabhji J

Diabetes Research and Clinical Practice. May 2024

(DOI : 10.1016/j.diabres.2024.111692)

The impact of excess body weight on employment outcomes: A systematic review of the evidence.

Kesaite V, Greve J

Economics and Human Biology. May 2024

(DOI : 10.1016/j.ehb.2024.101398)

Effect of 20 mph speed limits on traffic injuries in Edinburgh, UK: a natural experiment and modelling study.

Kokka KK, Nightingale G, Williams AJ, Abbas A, Popov V, Sharp S, Hunter RF, Jepson R, Woodcock J

Journal of Epidemiology and Community Health. May 2024

(DOI : 10.1136/jech-2023-221612)

Exploring residential relocation- differences between newcomers and settled residents in health, travel behaviour and neighbourhood perceptions.

Kienast-von Einem C, Panter J, Ogilvie D, Reid A

Health & place. May 2024

(DOI : 10.1016/j.healthplace.2024.103254)

Association between arterial health and cognition in adolescents: The PANIC study.

Jalanko P, Bond B, Laukkanen JA, Brage S, Ekelund U, Laitinen T, Määttä S, Kähönen M, Haapala EA, Lakka TA

Physiological reports. May 2024

(DOI : 10.14814/phy2.16024)

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, Chasman DI, Morris AP, Caulfield MJ, Hwang SJ, Kooner JS, Conen D, Attia JR, Morrison AC, Loos RJF, Kristiansson K, Schmidt R, Hicks AA, Pramstaller PP, Nelson CP, Samani NJ, Risch L, Gyllensten U, Melander O, Riese H, Wilson JF, Campbell H, Rich SS, Psaty BM, Lu Y, Rotter JI, Guo X, Rice KM, Vollenweider P, Sundström J, Langenberg C, Tobin MD, Giedraitis V, Luan J, Tuomilehto J, Kutalik Z, Ripatti S, Salomaa V, Girotto G, Trompet S, Jukema JW, van der Harst P, Ridker PM, Giulianini F, Vitart V, Goel A, Watkins H, Harris SE, Deary IJ, van der Most PJ, Oldehinkel AJ, Keavney BD, Hayward C, Campbell A, Boehnke M, Scott LJ, Boutin T, Mamasoula C, Järvelin MR, Peters A, Gieger C, Lakatta EG, Cucca F, Hui J, Knekt P, Enroth S, de Borst MH, Polasek O, Concas MP, Catamo E, Cocca M, Li-Gao R, Hofer E, Schmidt H, Spedicati B, Waldenberger M, Strachan DP, Laan M, Teumer A, Dörr M, Gudnason V, Cook JP, Ruggiero D, Kolcic I, Boerwinkle E, Traglia M, Lehtimäki T, Raitakari OT, Johnson AD, Newton-Cheh C, Brown MJ, Dominiczak AF, Sever PJ, Poulter N, Chambers JC, Elosua R, Siscovick D, Esko T, Metspalu A, Strawbridge RJ, Laakso M, Hamsten A, Hottenga JJ, de Geus E, Morris AD, Palmer CNA, Nolte IM, Milaneschi Y, Marten J, Wright A, Zeggini E, Howson JMM, O'Donnell CJ, Spector T, Nalls MA, Simonsick EM, Liu Y, van Duijn CM, Butterworth AS, Danesh JN, Menni C, Wareham NJ, Khaw KT, Sun YV, Wilson PWF, Cho K, Visscher PM, Denny JC, Million Veteran Program Million Veteran Program, Lifelines Cohort Study Lifelines Cohort Study, CHARGE consortium CHARGE consortium, ICBP Consortium ICBP Consortium, Levy D, Edwards TL, Munroe PB, Snieder H, Warren HR

Nature genetics. Apr 2024

(DOI : 10.1038/s41588-024-01714-w)

Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers.

Smith-Byrne K, Hedman Å, Dimitriou M, Desai T, Sokolov AV, Schioth HB, Koprulu M, Pietzner M, Langenberg C, Atkins J, Penha RC, McKay J, Brennan P, Zhou S, Richards BJ, Yarmolinsky J, Martin RM, Borlido J, Mu XJ, Butterworth A, Shen X, Wilson J, Assimes TL, Hung RJ, Amos C, Purdue M, Rothman N, Chanock S, Travis RC, Johansson M, Malarstig A

Nature communications. Apr 2024

(DOI : 10.1038/s41467-024-46834-3)

The impact of social media interventions on eating behaviours and diet in adolescents and young adults: a mixed methods systematic review protocol.

Tang H, Spreckley M, van Sluijs E, Ahern AL, Smith AD

BMJ Open. Apr 2024

(DOI : 10.1136/bmjopen-2023-083465)

Randomised controlled trial of population screening for atrial fibrillation in people aged 70 years and over to reduce stroke: protocol for the SAFER trial.

Mant J, Modi RN, Dymond A, Armstrong N, Burt J, Calvert P, Cowie M, Ding WY, Edwards D, Freedman B, Griffin SJ, Hoare S, Hobbs FDR, Johnson R, Kaptoge S, Lip GYH, Lobban T, Lown M, Lund J, McManus RJ, Mills MT, Morris S, Powell A, Proietti R, Sutton S, Sweeting M, Thom H, Williams K, SAFER author group SAFER author group

BMJ Open. Apr 2024

(DOI : 10.1136/bmjopen-2023-082047)

Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation.

Leeson-Payne A, Iyinikkel J, Malcolm C, Lam BYH, Sommer N, Dowsett GKC, Martinez de Morentin PB, Thompson D, Mackenzie A, Chianese R, Kentistou K, Gardner EJ, Perry JRB, Grassmann F, Speakman JR, Rochford JJ, Yeo GSH, Murray F, Heisler LK

Cell metabolism. Apr 2024

(DOI : 10.1016/j.cmet.2024.03.016)

Changes in the number of new takeaway food outlets associated with adoption of management zones around schools: A natural experimental evaluation in England.

Rahilly J, Amies-Cull B, Chang M, Cummins S, Derbyshire D, Hassan S, Huang Y, Keeble M, Liu B, Medina-Lara A, Mytton O, Rogers N, Savory B, Schiff A, Sharp SJ, Smith R, Thompson C, White M, Adams J, Burgoine T

SSM - Population Health. Apr 2024

(DOI : 10.1016/j.ssmph.2024.101646)

Global seroprevalence and prevalence of infection of influenza in dogs (Canis familiaris): A systematic review and meta-analysis.

Leung C, King AN, Barker PRA, Alshallal AD, Lee JY, Su L

Reviews in medical virology. Apr 2024

(DOI : 10.1002/rmv.2542)

Early outcomes of referrals to the English National Health Service Digital Weight Management Programme.

Taylor K, Indulkar T, Thompson B, Pinkard C, Barron E, Frost T, Jayawardane P, Davies N, Bakhai C, Forouhi NG, Aveyard P, Jebb S, Valabhji J

Obesity (Silver Spring, Md.). Apr 2024

(DOI : 10.1002/oby.24024)

State of the Art of Lifecourse Cohort Establishment.

Dai S, Qiu G, Li Y, Yang S, Jia P

China CDC weekly. Apr 2024

(DOI : 10.46234/ccdcw2024.058)

Screen time, social media use, and weight-related bullying victimization: Findings from an international sample of adolescents.

Ganson KT, Pang N, Nagata JM, Pedder Jones C, Mishna F, Testa A, Jackson DB, Hammond D

PLoS ONE. Apr 2024

(DOI : 10.1371/journal.pone.0299830)

Diet and physical activity interventions to improve cardiovascular disease risk factors in liver transplant recipients: Systematic review and meta-analysis.

Spillman LN, Stowe E, Madden AM, Rennie KL, Oude Griep LM, Allison M, Kenney L, O'Connor C, Griffin SJ

Transplantation reviews (Orlando, Fla.). Apr 2024

(DOI : 10.1016/j.trre.2024.100852)

Replacement of saturated fatty acids from meat by dairy sources in relation to incident cardiovascular disease: The European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study.

Vogtschmidt YD, Soedamah-Muthu SS, Imamura F, Givens DI, Lovegrove JA

The American Journal of Clinical Nutrition. Apr 2024

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Point-of-choice kilocalorie labelling practices in large, out-of-home food businesses: a preobservational versus post observational study of labelling practices following implementation of The Calorie Labelling (Out of Home Sector) (England) Regulations 2021.

Polden M, Jones A, Essman M, Adams J, Bishop T, Burgoine T, Donohue A, Sharp S, White M, Smith R, Robinson E

BMJ Open. Apr 2024

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Multisectoral interventions for urban health in Africa: a mixed-methods systematic review.

Thondoo M, Mogo ERI, Tatah L, Muti M, van Daalen KR, Muzenda T, Boscott R, Uwais O, Farmer G, Yue A, Dalzell S, Mukoma G, Bhagtani D, Matina S, Dambisya PM, Okop K, Ebikeme C, Micklesfield L, Oni T

Global health action. Apr 2024

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Perception and reality: The mismatch between absolute and relative physical activity intensity during pregnancy and postpartum in United States women.

Hesketh KR, Wen F, Herring AH, Siega-Riz AM, Evenson KR

Preventive medicine. Apr 2024

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Consolidated guidance for behavioral intervention pilot and feasibility studies.

Pfledderer CD, von Klinggraeff L, Burkart S, da Silva Bandeira A, Lubans DR, Jago R, Okely AD, van Sluijs EMF, Ioannidis JPA, Thrasher JF, Li X, Beets MW

Pilot and feasibility studies. Apr 2024

(DOI : 10.1186/s40814-024-01485-5)

Protein-truncating variants in BSN are associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease.

Zhao Y, Chukanova M, Kentistou KA, Fairhurst-Hunter Z, Siegert AM, Jia RY, Dowsett GKC, Gardner EJ, Lawler K, Day FR, Kaisinger LR, Tung YL, Lam BYH, Chen HC, Wang Q, Berumen-Campos J, Kuri-Morales P, Tapia-Conyer R, Alegre-Diaz J, Barroso I, Emberson J, Torres JM, Collins R, Saleheen D, Smith KR, Paul DS, Merkle F, Farooqi IS, Wareham NJ, Petrovski S, O'Rahilly S, Ong KK, Yeo GSH, Perry JRB

Nature genetics. Apr 2024

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Changes in the number and outcome of takeaway food outlet planning applications in response to adoption of management zones around schools in England: A time series analysis.

Rahilly J, Williams A, Chang M, Cummins S, Derbyshire D, Hassan S, Huang Y, Keeble M, Liu B, Medina-Lara A, Mytton O, Savory B, Schiff A, Sharp SJ, Smith R, Thompson C, White M, Adams J, Burgoine T

Health & place. Apr 2024

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Dual glucagon-like peptide-1 and glucagon receptor agonism reduces energy intake in type 2 diabetes with obesity.

Golubic R, Kennet J, Parker V, Robertson D, Luo D, Hansen L, Jermutus L, Ambery P, Ryaboshapkina M, Surakala M, Laker RC, Venables M, Koulman A, Park A, Evans M

Diabetes, obesity & metabolism. Apr 2024

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The effectiveness of pharmacological and lifestyle interventions to reduce the risk of diabetes and hyperglycaemia following gestational diabetes: A systematic review and meta-analysis.

Dennison RA, Oliver-Williams C, Qi HLJ, Kotecha D, Seed L, Ward RJ, Griffin SJ

Diabetic medicine : a journal of the British Diabetic Association. Mar 2024

(DOI : 10.1111/dme.15316)

Impact of the UK soft drinks industry levy on health and health inequalities in children and adolescents in England: An interrupted time series analysis and population health modelling study.

Cobiac LJ, Rogers NT, Adams J, Cummins S, Smith R, Mytton O, White M, Scarborough P

PLoS Medicine. Mar 2024

(DOI : 10.1371/journal.pmed.1004371)

Accumulating Sedentary Time and Physical Activity From Childhood to Adolescence and Cardiac Function in Adolescence.

Haapala EA, Leppänen MH, Lee E, Savonen K, Laukkanen JA, Kähönen M, Brage S, Lakka TA

Journal of the American Heart Association. Mar 2024

(DOI : 10.1161/JAHA.123.031837)

Dementias Platform UK: Bringing genetics into life.

Leonenko G, Bauermeister S, Ghanti D, Stevenson-Hoare J, Simmonds E, Brookes K, Morgan K, Chaturvedi N, Elliott P, Thomas A, Wareham N, Gallacher J, Escott-Price V

Alzheimer's & dementia : the journal of the Alzheimer's Association. Mar 2024

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Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation.

Thériault S, Li Z, Abner E, Luan J, Manikpurage HD, Houessou U, Zamani P, Briend M, Estonian Biobank Research Team Estonian Biobank Research Team, Boudreau DK, Gaudreault N, Frenette L, Argaud D, Dahmene M, Dagenais F, Clavel MA, Pibarot P, Arsenault BJ, Boekholdt SM, Wareham NJ, Esko T, Mathieu P, Bossé Y

Nature communications. Mar 2024

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Dietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case-cohort study.

Zheng JS, Steur M, Imamura F, Freisling H, Johnson L, van der Schouw YT, Tong TY, Weiderpass E, Bajracharya R, Crous-Bou M, Dahm CC, Heath AK, Ibsen DB, Jannasch F, Katzke V, Masala G, Moreno-Iribas C, Sacerdote C, Schulze MB, Sieri S, Wareham NJ, Danesh J, Butterworth AS, Forouhi NG

The American Journal of Clinical Nutrition. Mar 2024

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Changes in UK price disparities between healthy and less healthy foods over 10 years: An updated analysis with insights in the context of inflationary increases in the cost-of-living from 2021.

Hoenink JC, Garrott K, Jones NRV, Conklin AI, Monsivais P, Adams J

Appetite. Mar 2024

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The association between patterns of weight change, diabetes status and glycaemia among adults with overweight and obesity.

Yin R, Ahern AL, Lafortune L, Griffin SJ, Strelitz JM, Mueller J

Diabetes Research and Clinical Practice. Mar 2024

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A longitudinal area classification of migration in Great Britain: Testing the application of Group-Based Multi-Trajectory Modelling.

Kienast-von Einem C, Panter J, Reid A

Population, space and place. Mar 2024

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Multi-ancestry polygenic mechanisms of type 2 diabetes.

Smith K, Deutsch AJ, McGrail C, Kim H, Hsu S, Huerta-Chagoya A, Mandla R, Schroeder PH, Westerman KE, Szczerbinski L, Majarian TD, Kaur V, Williamson A, Zaitlen N, Claussnitzer M, Florez JC, Manning AK, Mercader JM, Gaulton KJ, Udler MS

Nature medicine. Mar 2024

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The Superblock model: A review of an innovative urban model for sustainability, liveability, health and well-being.

Nieuwenhuijsen M, de Nazelle A, Pradas MC, Daher C, Dzhambov AM, Echave C, Gössling S, Iungman T, Khreis H, Kirby N, Khomenko S, Leth U, Lorenz F, Matkovic V, Müller J, Palència L, Pereira Barboza E, Pérez K, Tatah L, Tiran J, Tonne C, Mueller N

Environmental research. Mar 2024

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Systemic proteome adaptions to 7-day complete caloric restriction in humans.

Pietzner M, Uluvar B, Kolnes KJ, Jeppesen PB, Frivold SV, Skattebo Ø, Johansen EI, Skålhegg BS, Wojtaszewski JFP, Kolnes AJ, Yeo GSH, O'Rahilly S, Jensen J, Langenberg C

Nature metabolism. Mar 2024

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Wellbeing Impact Study of High-Speed 2 (WISH2): Protocol for a mixed-methods examination of the impact of major transport infrastructure development on mental health and wellbeing.

Morley KI, Hocking L, Saunders CL, Bousfield JW, Bostock J, Brimicombe J, Burgoine T, Dawney J, Hofman J, Lee D, Mackett R, Phillips W, Sussex J, Morris S

PLoS ONE. Feb 2024

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Prevalence of loneliness and associations with health behaviours and body mass index in 5835 people living with and beyond cancer: a cross-sectional study.

Smith S, Lally P, Steptoe A, Chavez-Ugalde Y, Beeken RJ, Fisher A

BMC Public Health. Feb 2024

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The feasibility of population screening for paroxysmal atrial fibrillation using hand-held electrocardiogram devices.

Mant J, Modi RN, Charlton P, Dymond A, Massou E, Brimicombe J, Freedman B, Griffin SJ, Hobbs FDR, Lip GYH, McManus RJ, Williams K

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. Feb 2024

(DOI : 10.1093/europace/euae056)

Sex differences in energy balance, body composition, and metabolic and endocrine markers during prolonged arduous military training.

O'Leary TJ, Gifford RM, Knight RL, Wright J, Handford S, Venables MC, Reynolds RM, Woods D, Wardle SL, Greeves JP

Journal of applied physiology (Bethesda, Md. : 1985). Feb 2024

(DOI : 10.1152/japplphysiol.00864.2023)

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

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Nature. Feb 2024

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A Predictive Model for Thiamine Responsive Disorders among Infants and Young Children: Results from a Prospective Cohort Study in Lao People's Democratic Republic.

Smith TJ, Arnold CD, Fischer PR, Trehan I, Hiffler L, Sitthideth D, Stein-Wexler R, Yeh J, Jones KS, Hampel D, Tancredi DJ, Schick MA, McBeth CN, Tan X, Allen LH, Sayasone S, Kounnavong S, Hess SY

The Journal of pediatrics. Feb 2024

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Is rest-activity rhythm prospectively associated with all-cause mortality in older people regardless of sleep and physical activity level? The 'Como Vai?' Cohort study.

Wendt A, Bielemann RM, Wehrmeister FC, Ricardo LIC, Müller WA, Machado AKF, da Cruz MF, Bertoldi AD, Brage S, Ekelund U, Tovo-Rodrigues L, Crochemore-Silva I

PLoS ONE. Feb 2024

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Are school uniforms associated with gender inequalities in physical activity? A pooled analysis of population-level data from 135 countries/regions

Ryan M, Ricardo L, Nathan N, Hofmann R, van Sluijs E

Journal of sport and health science. Feb 2024

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Association of insulin resistance with the accumulation of saturated intramyocellular lipid: A comparison with other fat stores.

Azhar M, Watson LPE, De Lucia Rolfe E, Ferraro M, Carr K, Worsley J, Boesch C, Hodson L, Chatterjee KK, Kemp GJ, Savage DB, Sleigh A

NMR in biomedicine. Feb 2024

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Genetic determinants of micronucleus formation in vivo.

Adams DJ, Barlas B, McIntyre RE, Salguero I, van der Weyden L, Barros A, Vicente JR, Karimpour N, Haider A, Ranzani M, Turner G, Thompson NA, Harle V, Olvera-León R, Robles-Espinoza CD, Speak AO, Geisler N, Weninger WJ, Geyer SH, Hewinson J, Karp NA, Sanger Mouse Genetics Project Sanger Mouse Genetics Project, Fu B, Yang F, Kozik Z, Choudhary J, Yu L, van Ruiten MS, Rowland BD, Lelliott CJ, Del Castillo Velasco-Herrera M, Verstraten R, Bruckner L, Henssen AG, Rooimans MA, de Lange J, Mohun TJ, Arends MJ, Kentistou KA, Coelho PA, Zhao Y, Zecchini H, Perry JRB, Jackson SP, Balmus G

Nature. Feb 2024

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Relationship of fat mass ratio - a biomarker for lipodystrophy - with cardiometabolic traits.

Agrawal S, Luan J, Cummings BB, Weiss E, Wareham NJ, Khera AV

Diabetes. Feb 2024

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Weight gain during nutritional rehabilitation post-childhood malnutrition may influence the associations between adulthood desaturases activity and anthro-cardiometabolic risk factors.

Olga L, McKenzie K, Kerac M, Boyne M, Badaloo A, Bandsma RHJ, Koulman A, Thompson DS

Clinical nutrition (Edinburgh, Scotland). Feb 2024

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Noncommunicable diseases behavioural risk factors among secondary school adolescents in Urban Cameroon.

Changoh CM, Tatah L, Aroke D, Nsagha D, Choukem SP

BMC Public Health. Feb 2024

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Real-world nudging, pricing, and mobile physical activity coaching was insufficient to improve lifestyle behaviours and cardiometabolic health: the Supreme Nudge parallel cluster-randomised controlled supermarket trial.

Stuber JM, Mackenbach JD, de Bruijn GJ, Gillebaart M, Hoenink JC, Middel CNH, de Ridder DTD, van der Schouw YT, Smit EG, Velema E, Vos AL, Waterlander WE, Lakerveld J, Beulens JWJ, SUPREME NUDGE consortium SUPREME NUDGE consortium

BMC medicine. Feb 2024

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Avoiding conflicts of interest and reputational risks associated with population research on food and nutrition: the Food Research risK (FoRK) guidance and toolkit for researchers.

Cullerton K, Adams J, Forouhi NG, Francis O, White M

BMJ (Clinical research ed.). Jan 2024

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Prospective associations between changes in physical activity and sedentary time and subsequent lean muscle mass in older English adults: the EPIC-Norfolk cohort study.

Yerrakalva D, Hajna S, Khaw KT, Griffin SJ, Brage S

The international journal of behavioral nutrition and physical activity. Jan 2024

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Parliamentary reaction to the announcement and implementation of the UK Soft Drinks Industry Levy: applied thematic analysis of 2016-2020 parliamentary debates.

Jones CP, Lawlor ER, Forde H, Theis DRZ, Cummins S, Adams J, Smith R, Rayner M, Rutter H, Penney TL, Alliot O, Armitage S, White M

Public Health Nutrition. Jan 2024

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Gender Differences in Caregivers' Attitudes to Risky Child Play in Britain: A Cross-Sectional Study.

Smith AD, Dodd HF, Ricardo L, van Sluijs E

Journal of physical activity & health. Jan 2024

(DOI : 10.1123/jpah.2023-0676)

Agnogenic practices and corporate political strategy: the legitimation of UK gambling industry-funded youth education programmes.

van Schalkwyk MCI, Hawkins B, Petticrew M, Maani N, Garde A, Reeves A, McKee M

Health promotion international. Jan 2024

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A meta-analysis of previous falls and subsequent fracture risk in cohort studies.

Vandenput L, Johansson H, McCloskey EV, Liu E, Schini M, Åkesson KE, Anderson FA, Azagra R, Bager CL, Beaudart C, Bischoff-Ferrari HA, Biver E, Bruyère O, Cauley JA, Center JR, Chapurlat R, Christiansen C, Cooper C, Crandall CJ, Cummings SR, da Silva JAP, Dawson-Hughes B, Diez-Perez A, Dufour AB, Eisman JA, Elders PJM, Ferrari S, Fujita Y, Fujiwara S, Glüer CC, Goldshtein I, Goltzman D, Gudnason V, Hall J, Hans D, Hoff M, Hollick RJ, Huisman M, Iki M, Ish-Shalom S, Jones G, Karlsson MK, Khosla S, Kiel DP, Koh WP, Koromani F, Kotowicz MA, Kröger H, Kwok T, Lamy O, Langhammer A, Larijani B, Lippuner K, McGuigan FEA, Mellström D, Merlijn T, Nguyen TV, Nordström A, Nordström P, O'Neill TW, Obermayer-Pietsch B, Ohlsson C, Orwoll ES, Pasco JA, Rivadeneira F, Schott AM, Shiroma EJ, Siggeirsdottir K, Simonsick EM, Sornay-Rendu E, Sund R, Swart KMA, Szulc P, Tamaki J, Torgerson DJ, van Schoor NM, van Staa TP, Vila J, Wareham NJ, Wright NC, Yoshimura N, Zillikens M, Zwart M, Harvey NC, Lorentzon M, Leslie WD, Kanis JA

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. Jan 2024

(DOI : 10.1007/s00198-023-07012-1)

Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes.

Bradfield JP, Kember RL, Ulrich A, Balkiyarova Z, Alyass A, Aris IM, Bell JA, Broadaway KA, Chen Z, Chai JF, Davies NM, Fernandez-Orth D, Bustamante M, Fore R, Ganguli A, Heiskala A, Hottenga JJ, Íñiguez C, Kobes S, Leinonen J, Lowry E, Lyytikäinen LP, Mahajan A, Pitkänen N, Schnurr TM, Have CT, Strachan DP, Thiering E, Vogelezang S, Wade KH, Wang CA, Wong A, Holm LA, Chesi A, Choong C, Cruz M, Elliott P, Franks S, Frithioff-Bøjsøe C, Gauderman WJ, Glessner JT, Gilsanz V, Griesman K, Hanson RL, Kaakinen M, Kalkwarf H, Kelly A, Kindler J, Kähönen M, Lanca C, Lappe J, Lee NR, McCormack S, Mentch FD, Mitchell JA, Mononen N, Niinikoski H, Oken E, Pahkala K, Sim X, Teo YY, Baier LJ, van Beijsterveldt T, Adair LS, Boomsma DI, de Geus E, Guxens M, Eriksson JG, Felix JF, Gilliland FD, Biobank PM, Hansen T, Hardy R, Hivert MF, Holm JC, Jaddoe VWV, Järvelin MR, Lehtimäki T, Mackey DA, Meyre D, Mohlke KL, Mykkänen J, Oberfield S, Pennell CE, Perry JRB, Raitakari O, Rivadeneira F, Saw SM, Sebert S, Shepherd JA, Standl M, Sørensen TIA, Timpson NJ, Torrent M, Willemsen G, Hyppönen E, Power C, Early Growth Genetics Consortium Early Growth Genetics Consortium, McCarthy MI, Freathy RM, Widén E, Hakonarson H, Prokopenko I, Voight BF, Zemel BS, Grant SFA, Cousminer DL