MRC Epidemiology Unit

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programme => Nutritional Epidemiology

Combined associations of physical activity, diet quality and their trajectories with incidence of diabetes and cardiovascular diseases in the EPIC-Norfolk Study.

Aryannezhad S, Imamura F, Mok A, Wareham NJ, Forouhi NG, Brage S, Wareham N, Forouhi N

Scientific reports Apr 2025

(DOI : 10.1038/s41598-025-93679-x)

Plasma Concentration of 36 (Poly)phenols and Prospective Body Weight Change in Participants from the EPIC Cohort.

Gil-Lespinard M, Almanza-Aguilera E, Castañeda J, Guiñón-Fort D, Eriksen AK, Tjønneland A, Rothwell JA, Shah S, Cadeau C, Katzke V, Johnson T, Schulze MB, Oliverio A, Pasanisi F, Tumino R, Manfredi L, Masala G, Skeie G, Lundblad MW, Brustad M, Lasheras C, Crous-Bou M, Molina-Montes E, Colorado-Yohar S, Guevara M, Amiano P, Johansson I, Hultdin J, Forouhi NG, Freisling H, Merdas M, Debras C, Heath AK, Aglago EK, Aune D, Zamora-Ros R

Annals of nutrition & metabolism Jan 2025

(DOI : 10.1159/000535803)

Examining causal relationships between educational attainment and type 2 diabetes using genetic analysis: findings from the EPIC-InterAct study through Mendelian randomisation.

Macciotta A, Sacerdote C, Giachino C, Di Girolamo C, Franco M, van der Schouw YT, Zamora-Ros R, Weiderpass E, Domenighetti C, Elbaz A, Truong T, Agnoli C, Bendinelli B, Panico S, Vineis P, Christakoudi S, Schulze MB, Katzke V, Bajracharya R, Dahm CC, Dalton SO, Colorado-Yohar SM, Moreno-Iribas C, Etxezarreta PA, Sánchez MJ, Forouhi NG, Wareham N, Ricceri F

Journal of Epidemiology and Community Health Dec 2024

(DOI : 10.1136/jech-2024-222734)

Effects of coconut oil, olive oil, and butter on plasma fatty acids and metabolic risk factors: a randomized trial.

Sowah SA, Koulman A, Sharp SJ, Imamura F, Khaw KT, Forouhi NG

Journal of lipid research Nov 2024

(DOI : 10.1016/j.jlr.2024.100681)

Combined associations of physical activity, diet quality and their changes over time with mortality: findings from the EPIC-Norfolk study, United Kingdom.

Aryannezhad S, Mok A, Imamura F, Wareham NJ, Brage S, Forouhi NG

BMC medicine Oct 2024

(DOI : 10.1186/s12916-024-03668-6)

Associations of takeaway outlets with takeaway food consumption and adiposity: longitudinal analysis of the Fenland cohort.

Hoenink JC, Burgoine T, Forouhi NG, Monsivais P, Sharp SJ, Panter J, Adams J

Obesity (Silver Spring, Md.) Oct 2024

(DOI : 10.1002/oby.24152)

Recent advances in precision nutrition and cardiometabolic diseases.

Martínez-González MÁ, Planes FJ, Ruiz-Canela M, Toledo E, Estruch R, Salas-Salvadó J, Valdés-Más R, Mena P, Castañer O, Fitó M, Clish C, Landberg R, Wittenbecher C, Liang L, Guasch-Ferré M, Lamuela-Raventós RM, Wang DD, Forouhi N, Razquin C, B Hu F

Revista espanola de cardiologia (English ed.) Oct 2024

(DOI : 10.1016/j.rec.2024.09.003)

Meat consumption and incident type 2 diabetes: an individual-participant federated meta-analysis of 1·97 million adults with 100 000 incident cases from 31 cohorts in 20 countries.

Li C, Bishop TRP, Imamura F, Sharp SJ, Pearce M, Brage S, Ong KK, Ahsan H, Bes-Rastrollo M, Beulens JWJ, den Braver N, Byberg L, Canhada S, Chen Z, Chung HF, Cortes-Valencia A, Djoussé L, Drouin-Chartier JP, Du H, Du S, Duncan BB, Gaziano JM, Gordon-Larsen P, Goto A, Haghighatdoost F, Härkänen T, Hashemian M, Hu FB, Ittermann T, Järvinen R, Kakkoura MG, Neelakantan N, Knekt P, Lajous M, Li Y, Magliano DJ, Malekzadeh R, Le Marchand L, Marques-Vidal P, Martínez-González MÁ, Maskarinec G, Mishra GD, Mohammadifard N, O'Donoghue G, O'Gorman D, Popkin B, Poustchi H, Sarrafzadegan N, Sawada N, Schmidt MI, Shaw JE, Soedamah-Muthu S, Stern D, Tong L, van Dam RM, Völzke H, Willett WC, Wolk A, Yu C, EPIC-InterAct Consortium EPIC-InterAct Consortium, Forouhi NG, Wareham NJ

The lancet. Diabetes & endocrinology Aug 2024

(DOI : 10.1016/S2213-8587(24)00179-7)

The Adaptation, Implementation, and Performance Evaluation of Intake24, a Digital 24-h Dietary Recall Tool for South Asian Populations: The South Asia Biobank.

Bhagtani D, Amoutzopoulos B, Steer T, Collins D, Abraham S, Holmes BA, Rai BK, Pradeepa R, Mahmood S, Shamim AA, Mathur P, Athauda L, De Silva L, Khawaja KI, Jha V, Kasturiratne A, Katulanda P, Mridha MK, Anjana RM, Chambers JC, Page P, Forouhi NG, Forouhi N

Current developments in nutrition Aug 2024

(DOI : 10.1016/j.cdnut.2025.104543)

A systematic evaluation of seven different scores representing the EAT-Lancet reference diet and mortality, stroke, and greenhouse gas emissions in three cohorts.

Stubbendorff A, Stern D, Ericson U, Sonestedt E, Hallström E, Borné Y, Lajous M, Forouhi NG, Olsen A, Dahm CC, Ibsen DB

The Lancet. Planetary health Jun 2024

(DOI : 10.1016/S2542-5196(24)00094-9)

Sugar-Sweetened Beverage Consumption and Height Loss in Adults: A Longitudinal Analysis in the EPIC-Norfolk Study.

Lee JY, Imamura F

The Journal of nutrition May 2024

(DOI : 10.1016/j.tjnut.2024.05.007)

Early outcomes of referrals to the English National Health Service Digital Weight Management Programme.

Taylor K, Indulkar T, Thompson B, Pinkard C, Barron E, Frost T, Jayawardane P, Davies N, Bakhai C, Forouhi NG, Aveyard P, Jebb S, Valabhji J

Obesity (Silver Spring, Md.) Apr 2024

(DOI : 10.1002/oby.24024)

Replacement of saturated fatty acids from meat by dairy sources in relation to incident cardiovascular disease: The European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study.

Vogtschmidt YD, Soedamah-Muthu SS, Imamura F, Givens DI, Lovegrove JA

The American Journal of Clinical Nutrition Apr 2024

(DOI : 10.1016/j.ajcnut.2024.04.007)

Dietary intake of plant- and animal-derived protein and incident cardiovascular diseases: the pan-European EPIC-CVD case-cohort study.

Zheng JS, Steur M, Imamura F, Freisling H, Johnson L, van der Schouw YT, Tong TY, Weiderpass E, Bajracharya R, Crous-Bou M, Dahm CC, Heath AK, Ibsen DB, Jannasch F, Katzke V, Masala G, Moreno-Iribas C, Sacerdote C, Schulze MB, Sieri S, Wareham NJ, Danesh J, Butterworth AS, Forouhi NG

The American Journal of Clinical Nutrition Mar 2024

(DOI : 10.1016/j.ajcnut.2024.03.006)

Avoiding conflicts of interest and reputational risks associated with population research on food and nutrition: the Food Research risK (FoRK) guidance and toolkit for researchers.

Cullerton K, Adams J, Forouhi NG, Francis O, White M

BMJ (Clinical research ed.) Jan 2024

(DOI : 10.1136/bmj-2023-077908)

Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies.

O'Keefe JH, Tintle NL, Harris WS, O'Keefe EL, Sala-Vila A, Attia J, Garg GM, Hure A, Bork CS, Schmidt EB, Venø SK, Chien KL, Chen YA, Egert S, Feldreich TR, Ärnlöv J, Lind L, Forouhi NG, Geleijnse JM, Pertiwi K, Imamura F, de Mello Laaksonen V, Uusitupa WM, Tuomilehto J, Laakso M, Lankinen MA, Laurin D, Carmichael PH, Lindsay J, Leander K, Laguzzi F, Swenson BR, Longstreth WT, Manson JE, Mora S, Cook NR, Marklund M, Melo van Lent D, Murphy R, Gudnason V, Ninomiya T, Hirakawa Y, Qian F, Sun Q, Hu F, Ardisson Korat AV, Riserus U, Lázaro I, Samieri C, Le Goff M, Helmer C, Steur M, Voortman T, Ikram MK, Tanaka T, Das JK, Ferrucci L, Bandinelli S, Tsai M, Guan W, Garg P, Verschuren WMM, Boer JMA, Biokstra A, Virtanen J, Wagner M, Westra J, Albuisson L, Yamagishi K, Siscovick DS, Lemaitre RN, Mozaffarian D

Stroke Dec 2023

(DOI : 10.1161/STROKEAHA.123.044281)

Plasma Metabolites Related to the Consumption of Different Types of Dairy Products and Their Association with New-Onset Type 2 Diabetes: Analyses in the Fenland and EPIC-Norfolk Studies, United Kingdom.

Trichia E, Koulman A, Stewart ID, Brage S, Griffin SJ, Griffin JL, Khaw KT, Langenberg C, Wareham NJ, Imamura F, Forouhi NG

Molecular nutrition & food research Dec 2023

(DOI : 10.1002/mnfr.202300154)

Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries.

Tong TYN, Clarke R, Schmidt JA, Huybrechts I, Noor U, Forouhi NG, Imamura F, Travis RC, Weiderpass E, Aleksandrova K, Dahm CC, van der Schouw YT, Overvad K, Kyrø C, Tjønneland A, Kaaks R, Katzke V, Schiborn C, Schulze MB, Mayen-Chacon AL, Masala G, Sieri S, De Magistris MS, Tumino R, Sacerdote C, Boer JMA, Verschuren WMM, Brustad M, Nøst TH, Crous-Bou M, Petrova D, Amiano P, Huerta JM, Moreno-Iribas C, Engström G, Melander O, Johansson K, Lindvall K, Aglago EK, Heath AK, Butterworth AS, Danesh J, Key TJ

European journal of nutrition Oct 2023

(DOI : 10.1007/s00394-023-03251-4)

Omega-6 fatty acid biomarkers and incident atrial fibrillation: an individual participant-level pooled analysis of 11 international prospective studies.

Garg PK, Guan W, Nomura S, Weir NL, Tintle N, Virtanen JK, Hirakawa Y, Qian F, Sun Q, Rimm E, Lemaitre RN, Jensen PN, Heckbert SR, Imamura F, Steur M, Leander K, Laguzzi F, Voortman T, Ninomiya T, Mozaffarian D, Harris WS, Siscovick DS, Tsai MY, Fatty Acids and Outcomes Research Consortium (FORCE) Fatty Acids and Outcomes Research Consortium (FORCE)

The American Journal of Clinical Nutrition Sep 2023

(DOI : 10.1016/j.ajcnut.2023.09.008)

GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.

Lagou V, Jiang L, Ulrich A, Zudina L, González KSG, Balkhiyarova Z, Faggian A, Maina JG, Chen S, Todorov PV, Sharapov S, David A, Marullo L, Mägi R, Rujan RM, Ahlqvist E, Thorleifsson G, Gao Η, Εvangelou Ε, Benyamin B, Scott RA, Isaacs A, Zhao JH, Willems SM, Johnson T, Gieger C, Grallert H, Meisinger C, Müller-Nurasyid M, Strawbridge RJ, Goel A, Rybin D, Albrecht E, Jackson AU, Stringham HM, Corrêa IR, Farber-Eger E, Steinthorsdottir V, Uitterlinden AG, Munroe PB, Brown MJ, Schmidberger J, Holmen O, Thorand B, Hveem K, Wilsgaard T, Mohlke KL, Wang Z, GWA-PA Consortium GWA-PA Consortium, Shmeliov A, den Hoed M, Loos RJF, Kratzer W, Haenle M, Koenig W, Boehm BO, Tan TM, Tomas A, Salem V, Barroso I, Tuomilehto J, Boehnke M, Florez JC, Hamsten A, Watkins H, Njølstad I, Wichmann HE, Caulfield MJ, Khaw KT, van Duijn CM, Hofman A, Wareham NJ, Langenberg C, Whitfield JB, Martin NG, Montgomery G, Scapoli C, Tzoulaki I, Elliott P, Thorsteinsdottir U, Stefansson K, Brittain EL, McCarthy MI, Froguel P, Sexton PM, Wootten D, Groop L, Dupuis J, Meigs JB, Deganutti G, Demirkan A, Pers TH, Reynolds CA, Aulchenko YS, Kaakinen MA, Jones B, Prokopenko I, Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC) Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC)

Nature genetics Sep 2023

(DOI : 10.1038/s41588-023-01462-3)

Omega-3 Fatty Acid Biomarkers and Incident Atrial Fibrillation.

Qian F, Tintle N, Jensen PN, Lemaitre RN, Imamura F, Feldreich TR, Nomura SO, Guan W, Laguzzi F, Kim E, Virtanen JK, Steur M, Bork CS, Hirakawa Y, O'Donoghue ML, Sala-Vila A, Ardisson Korat AV, Sun Q, Rimm EB, Psaty BM, Heckbert SR, Forouhi NG, Wareham NJ, Marklund M, Riserus U, Lind L, Ärnlöv J, Garg P, Tsai MY, Pankow J, Misialek JR, Gigante B, Leander K, Pester JA, Albert CM, Kavousi M, Ikram A, Voortman T, Schmidt EB, Ninomiya T, Morrow DA, Bayés-Genís A, O'Keefe JH, Ong KL, Wu JHY, Mozaffarian D, Harris WS, Siscovick DS, Fatty Acids and Outcomes Research Consortium (FORCE) Fatty Acids and Outcomes Research Consortium (FORCE)

Journal of the American College of Cardiology Jul 2023

(DOI : 10.1016/j.jacc.2023.05.024)

Interaction between plasma phospholipid odd-chain fatty acids and GAD65 autoantibodies on the incidence of adult-onset diabetes: the EPIC-InterAct case-cohort study.

Lampousi AM, Carlsson S, Löfvenborg JE, Cabrera-Castro N, Chirlaque MD, Fagherazzi G, Franks PW, Hampe CS, Jakszyn P, Koulman A, Kyrø C, Moreno-Iribas C, Nilsson PM, Panico S, Papier K, van der Schouw YT, Schulze MB, Weiderpass E, Zamora-Ros R, Forouhi NG, Sharp SJ, Rolandsson O, Wareham NJ

Diabetologia Jun 2023

(DOI : 10.1007/s00125-023-05948-x)

Nutritional Intake after Liver Transplant: Systematic Review and Meta-Analysis.

Spillman LN, Madden AM, Richardson H, Imamura F, Jones D, Nash M, Lim HK, Hellawell HN, Rennie KL, Oude Griep LM, Allison M, Griffin SJ

Nutrients Jun 2023

(DOI : 10.3390/nu15112487)

Resting heart rate is a population-level biomarker of cardiorespiratory fitness: The Fenland Study.

Gonzales TI, Jeon JY, Lindsay T, Westgate K, Perez-Pozuelo I, Hollidge S, Wijndaele K, Rennie K, Forouhi N, Griffin S, Wareham N, Brage S

PLoS ONE May 2023

(DOI : 10.1371/journal.pone.0285272)

A nutritional biomarker score of the Mediterranean diet and incident type 2 diabetes: Integrated analysis of data from the MedLey randomised controlled trial and the EPIC-InterAct case-cohort study.

Sobiecki JG, Imamura F, Davis CR, Sharp SJ, Koulman A, Hodgson JM, Guevara M, Schulze MB, Zheng JS, Agnoli C, Bonet C, Colorado-Yohar SM, Fagherazzi G, Franks PW, Gundersen TE, Jannasch F, Kaaks R, Katzke V, Molina-Montes E, Nilsson PM, Palli D, Panico S, Papier K, Rolandsson O, Sacerdote C, Tjønneland A, Tong TYN, van der Schouw YT, Danesh J, Butterworth AS, Riboli E, Murphy KJ, Wareham NJ, Forouhi NG

PLoS Medicine Apr 2023

(DOI : 10.1371/journal.pmed.1004221)

The moderating role of eating behaviour traits in the association between exposure to hot food takeaway outlets and body fatness.

Hoenink JC, Burgoine T, Brage S, Forouhi N, Griffin SJ, Monsivais P, Wareham NJ, Ahern A, Adams J

International journal of obesity (2005) Mar 2023

(DOI : 10.1038/s41366-023-01290-9)

Embracing complexity: making sense of diet, nutrition, obesity and type 2 diabetes.

Forouhi NG

Diabetologia Feb 2023

(DOI : 10.1007/s00125-023-05873-z)

Association between classes and subclasses of polyphenol intake and 5-year body weight changes in the EPIC-PANACEA study.

Castañeda J, Gil-Lespinard M, Almanza-Aguilera E, Llaha F, Gómez JH, Bondonno N, Tjønneland A, Overvad K, Katzke V, Schulze MB, Masala G, Agnoli C, Santucci De Magistris M, Tumino R, Sacerdote C, Skeie G, Brustad M, Lasheras C, Molina-Montes E, Chirlaque MD, Barricarte A, Sonestedt E, da Silva M, Johansson I, Hultdin J, May AM, Forouhi NG, Heath AK, Freisling H, Weiderpass E, Scalbert A, Zamora-Ros R

Obesity (Silver Spring, Md.) Jan 2023

(DOI : 10.1002/oby.23689)

The association between plasma zinc concentrations and markers of glucose metabolism in adults in Cameroon.

Mba CM, Jones KS, Forouhi NG, Imamura F, Assah F, Mbanya JC, Wareham NJ

The British journal of nutrition Jan 2023

(DOI : 10.1017/S0007114523000223)

Dietary Intake of 91 Individual Polyphenols and 5-Year Body Weight Change in the EPIC-PANACEA Cohort.

Gil-Lespinard M, Castañeda J, Almanza-Aguilera E, Gómez JH, Tjønneland A, Kyrø C, Overvad K, Katzke V, Schulze MB, Masala G, Agnoli C, Santucci De Magistris M, Tumino R, Sacerdote C, Skeie G, Lasheras C, Molina-Montes E, Huerta JM, Barricarte A, Amiano P, Sonestedt E, da Silva M, Johansson I, Hultdin J, May AM, Forouhi NG, Heath AK, Freisling H, Weiderpass E, Scalbert A, Zamora-Ros R

Antioxidants (Basel, Switzerland) Dec 2022

(DOI : 10.3390/antiox11122425)

Characterization of the degree of food processing in the European Prospective Investigation into Cancer and Nutrition: Application of the Nova classification and validation using selected biomarkers of food processing.

Huybrechts I, Rauber F, Nicolas G, Casagrande C, Kliemann N, Wedekind R, Biessy C, Scalbert A, Touvier M, Aleksandrova K, Jakszyn P, Skeie G, Bajracharya R, Boer JMA, Borné Y, Chajès V, Dahm CC, Dansero L, Guevara M, Heath AK, Ibsen DB, Papier K, Katzke V, Kyrø C, Masala G, Molina-Montes E, Robinson OJK, Santiuste de Pablos C, Schulze MB, Simeon V, Sonestedt E, Tjønneland A, Tumino R, van der Schouw YT, Verschuren WMM, Vozar B, Winkvist A, Gunter MJ, Monteiro CA, Millett C, Levy RB

Frontiers in nutrition Dec 2022

(DOI : 10.3389/fnut.2022.1035580)

Descriptive Epidemiology of Cardiorespiratory Fitness in UK Adults: The Fenland Study.

Gonzales TI, Westgate K, Hollidge S, Lindsay T, Wijndaele K, Forouhi NG, Griffin S, Wareham N, Brage S

Medicine and Science in Sports and Exercise Oct 2022

(DOI : 10.1249/MSS.0000000000003068)

External validation of a prediction model for estimating fat mass in children and adolescents in 19 countries: individual participant data meta-analysis.

Hudda MT, Wells JCK, Adair LS, Alvero-Cruz JRA, Ashby-Thompson MN, Ballesteros-Vásquez MN, Barrera-Exposito J, Caballero B, Carnero EA, Cleghorn GJ, Davies PSW, Desmond M, Devakumar D, Gallagher D, Guerrero-Alcocer EV, Haschke F, Horlick M, Ben Jemaa H, Khan AI, Mankai A, Monyeki MA, Nashandi HL, Ortiz-Hernandez L, Plasqui G, Reichert FF, Robles-Sardin AE, Rush E, Shypailo RJ, Sobiecki JG, Ten Hoor GA, Valdés J, Wickramasinghe VP, Wong WW, Riley RD, Owen CG, Whincup PH, Nightingale CM

BMJ (Clinical research ed.) Sep 2022

(DOI : 10.1136/bmj-2022-071185)

Association between circulating 25-hydroxyvitamin D and cardiometabolic risk factors in adults in rural and urban settings.

Mba CM, Koulman A, Forouhi NG, Sharp SJ, Imamura F, Jones K, Meadows SR, Assah F, Mbanya JC, Wareham NJ

Nutrition & diabetes Jul 2022

(DOI : 10.1038/s41387-022-00215-1)

Do not routinely test for vitamin D.

McChesney C, Singer A, Duquette D, Forouhi NG, Levinson W

BMJ (Clinical research ed.) Jul 2022

(DOI : 10.1136/bmj-2022-070270)

Using genetic variation to disentangle the complex relationship between food intake and health outcomes.

Pirastu N, McDonnell C, Grzeszkowiak EJ, Mounier N, Imamura F, Merino J, Day FR, Zheng J, Taba N, Concas MP, Repetto L, Kentistou KA, Robino A, Esko T, Joshi PK, Fischer K, Ong KK, Gaunt TR, Kutalik Z, Perry JRB, Wilson JF

PLoS genetics Jun 2022

(DOI : 10.1371/journal.pgen.1010162)

Associations between exploratory dietary patterns and incident type 2 diabetes: a federated meta-analysis of individual participant data from 25 cohort studies.

Jannasch F, Dietrich S, Bishop TRP, Pearce M, Fanidi A, O'Donoghue G, O'Gorman D, Marques-Vidal P, Vollenweider P, Bes-Rastrollo M, Byberg L, Wolk A, Hashemian M, Malekzadeh R, Poustchi H, Luft VC, de Matos SMA, Kim J, Kim MK, Kim Y, Stern D, Lajous M, Magliano DJ, Shaw JE, Akbaraly T, Kivimaki M, Maskarinec G, Le Marchand L, Martínez-González MÁ, Soedamah-Muthu SS, EPIC-InterAct Consortium EPIC-InterAct Consortium, Wareham NJ, Forouhi NG, Schulze MB

European journal of nutrition Jun 2022

(DOI : 10.1007/s00394-022-02909-9)

Dietary Patterns, Food Insecurity, and Their Relationships with Food Sources and Social Determinants in Two Small Island Developing States.

Bhagtani D, Augustus E, Haynes E, Iese V, Brown CR, Fesaitu J, Hambleton I, Badrie N, Kroll F, Saint-Ville A, Samuels TA, Forouhi NG, Benjamin-Neelon SE, Unwin N, On Behalf Of The CFaH Team

Nutrients May 2022

(DOI : 10.3390/nu14142891)

Lower carbohydrate diets for adults with type 2 diabetes.

Singh M, Hung ES, Cullum A, Allen RE, Aggett PJ, Dyson P, Forouhi NG, Greenwood DC, Pryke R, Taylor R, Twenefour D, Waxman R, Young IS

Diabetic medicine : a journal of the British Diabetic Association Dec 2021

(DOI : 10.1111/dme.14674)

Dietary Fatty Acids, Macronutrient Substitutions, Food Sources and Incidence of Coronary Heart Disease: Findings From the EPIC-CVD Case-Cohort Study Across Nine European Countries.

Steur M, Johnson L, Sharp SJ, Imamura F, Sluijs I, Key TJ, Wood A, Chowdhury R, Guevara M, Jakobsen MU, Johansson I, Koulman A, Overvad K, Sánchez MJ, van der Schouw YT, Trichopoulou A, Weiderpass E, Wennberg M, Zheng JS, Boeing H, Boer JMA, Boutron-Ruault MC, Ericson U, Heath AK, Huybrechts I, Imaz L, Kaaks R, Krogh V, Kühn T, Kyrø C, Masala G, Melander O, Moreno-Iribas C, Panico S, Quirós JR, Rodriguez-Barranco M, Sacerdote C, Santiuste C, Skeie G, Tjønneland A, Tumino R, Verschuren WMM, Zamora-Ros R, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Riboli E, Wareham NJ, Danesh J, Butterworth AS, Forouhi NG

Journal of the American Heart Association Nov 2021

(DOI : 10.1161/JAHA.120.019814)

Physical activity attenuates but does not eliminate coronary heart disease risk amongst adults with risk factors: EPIC-CVD case-cohort study.

Fortuin-de Smidt MC, Sewe MO, Lassale C, Weiderpass E, Andersson J, Huerta JM, Ekelund U, Aleksandrova K, Tong TY, Dahm CC, Tjønneland A, Kyrø C, Steindorf K, Schulze MB, Katzke V, Sacerdote C, Agnoli C, Masala G, Tumino R, Panico S, Boer JM, Onland-Moret NC, Wendel-Vos GW, van der Schouw YT, Borch KB, Agudo A, Petrova D, Chirlaque MD, Conchi MI, Amiano P, Melander O, Heath AK, Aune D, Forouhi NG, Langenberg C, Brage S, Riboli E, Wareham NJ, Danesh J, Butterworth AS, Wennberg P

European Journal of Preventive Cardiology Nov 2021

(DOI : 10.1093/eurjpc/zwac055)

Associations of Serum Folate and Holotranscobalamin with Cardiometabolic Risk Factors in Rural and Urban Cameroon.

Mba CM, Koulman A, Forouhi NG, Imamura F, Assah F, Mbanya JC, Wareham NJ

Nutrients Nov 2021

(DOI : 10.3390/nu14010178)

Lower carbohydrate diets for adults with type 2 diabetes.

Singh M, Hung ES, Cullum A, Allen RE, Aggett PJ, Dyson P, Forouhi NG, Greenwood DC, Pryke R, Taylor R, Twenefour D, Waxman R, Young IS

The British journal of nutrition Nov 2021

(DOI : 10.1017/S0007114521002373)

Milk intake and incident stroke and coronary heart disease in populations of European descent: A Mendelian Randomization study.

Vissers LET, Sluijs I, Burgess S, Forouhi NG, Freisling H, Imamura F, Nilsson TK, Renstrom F, Weiderpass E, Aleksandrova K, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Aune D, Bonet C, Boer JMA, Boeing H, Chirlaque MD, Conchi MI, Imaz L, Jäger S, Krogh V, Kyrø C, Masala G, Melander O, Overvad K, Panico S, Sánches MJ, Sonestedt E, Tjønneland A, Tzoulaki I, Verschuren WMM, Riboli E, Wareham NJ, Danesh J, Butterworth AS, van der Schouw YT

The British journal of nutrition Oct 2021

(DOI : 10.1017/S0007114521004244)

Trans Fatty Acid Biomarkers and Incident Type 2 Diabetes: Pooled Analysis of 12 Prospective Cohort Studies in the Fatty Acids and Outcomes Research Consortium (FORCE).

Lai HTM, Imamura F, Korat AVA, Murphy RA, Tintle N, Bassett JK, Chen J, Kröger J, Chien KL, Senn M, Wood AC, Forouhi NG, Schulze MB, Harris WS, Vasan RS, Hu F, Giles GG, Hodge A, Djoussé L, Brouwer IA, Qian F, Sun Q, Wu JHY, Marklund M, Lemaitre RN, Siscovick DS, Fretts AM, Shadyab AH, Manson JE, Howard BV, Robinson JG, Wallace RB, Wareham NJ, Chen YI, Rotter JI, Tsai MY, Micha R, Mozaffarian D, Fatty Acids and Outcomes Research Consortium (FORCE)

Diabetes care Aug 2021

(DOI : 10.2337/dc21-1756)

Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations.

Haslam DE, Peloso GM, Guirette M, Imamura F, Bartz TM, Pitsillides AN, Wang CA, Li-Gao R, Westra JM, Pitkänen N, Young KL, Graff M, Wood AC, Braun KVE, Luan J, Kähönen M, Kiefte-de Jong JC, Ghanbari M, Tintle N, Lemaitre RN, Mook-Kanamori DO, North K, Helminen M, Mossavar-Rahmani Y, Snetselaar L, Martin LW, Viikari JS, Oddy WH, Pennell CE, Rosendall FR, Ikram MA, Uitterlinden AG, Psaty BM, Mozaffarian D, Rotter JI, Taylor KD, Lehtimäki T, Raitakari OT, Livingston KA, Voortman T, Forouhi NG, Wareham NJ, de Mutsert R, Rich SS, Manson JE, Mora S, Ridker PM, Merino J, Meigs JB, Dashti HS, Chasman DI, Lichtenstein AH, Smith CE, Dupuis J, Herman MA, McKeown NM

Circulation. Genomic and precision medicine Jul 2021

(DOI : 10.1161/CIRCGEN.120.003288)

Nutritional basis of type 2 diabetes remission.

Taylor R, Ramachandran A, Yancy WS, Forouhi NG

BMJ (Clinical research ed.) Jul 2021

(DOI : 10.1136/bmj.n1449)

Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses.

Emerging Risk Factors Collaboration/EPIC-CVD/Vitamin D Studies Collaboration

The lancet. Diabetes & endocrinology May 2021

(DOI : 10.1016/S2213-8587(21)00263-1)

More Evidence for 5-a-Day for Fruit and Vegetables and a Greater Need for Translating Dietary Research Evidence to Practice.

Sattar N, Forouhi NG

Circulation Apr 2021

(DOI : 10.1161/CIRCULATIONAHA.121.053293)

Prepubertal Dietary and Plasma Phospholipid Fatty Acids Related to Puberty Timing: Longitudinal Cohort and Mendelian Randomization Analyses.

Cheng TS, Day FR, Perry JRB, Luan J, Langenberg C, Forouhi NG, Wareham NJ, Ong KK

Nutrients Apr 2021

(DOI : 10.3390/nu13061868)

Heterogeneity of Associations between Total and Types of Fish Intake and the Incidence of Type 2 Diabetes: Federated Meta-Analysis of 28 Prospective Studies Including 956,122 Participants.

Pastorino S, Bishop T, Sharp SJ, Pearce M, Akbaraly T, Barbieri NB, Bes-Rastrollo M, Beulens JWJ, Chen Z, Du H, Duncan BB, Goto A, Härkänen T, Hashemian M, Kromhout D, Järvinen R, Kivimaki M, Knekt P, Lin X, Lund E, Magliano DJ, Malekzadeh R, Martínez-González MÁ, O'Donoghue G, O'Gorman D, Poustchi H, Rylander C, Sawada N, Shaw JE, Schmidt M, Soedamah-Muthu SS, Sun L, Wen W, Wolk A, Shu XO, Zheng W, Wareham NJ, Forouhi NG

Nutrients Apr 2021

(DOI : 10.3390/nu13041223)

Joint associations between objectively measured physical activity volume and intensity with body fatness: the Fenland study.

Lindsay T, Wijndaele K, Westgate K, Dempsey P, Strain T, De Lucia Rolfe E, Forouhi NG, Griffin S, Wareham NJ, Brage S

International Journal of Obesity Mar 2021

(DOI : 10.1038/s41366-021-00970-8)

Vitamin D and covid-19.

Vimaleswaran KS, Forouhi NG, Khunti K

BMJ (Clinical research ed.) Mar 2021

(DOI : 10.1136/bmj.n544)

Data Resource Profile: Understanding the patterns and determinants of health in South Asians-the South Asia Biobank.

Song P, Gupta A, Goon IY, Hasan M, Mahmood S, Pradeepa R, Siddiqui S, Frost GS, Kusuma D, Miraldo M, Sassi F, Wareham NJ, Ahmed S, Anjana RM, Brage S, Forouhi NG, Jha S, Kasturiratne A, Katulanda P, Khawaja KI, Loh M, Mridha MK, Wickremasinghe AR, Kooner JS, Chambers JC, South Asia Biobank

International Journal of Epidemiology Feb 2021

(DOI : 10.1093/ije/dyab029)

Independent and combined associations between fast-food outlet exposure and genetic risk for obesity: a population-based, cross-sectional study in the UK.

Burgoine T, Monsivais P, Sharp SJ, Forouhi NG, Wareham NJ

BMC medicine Feb 2021

(DOI : 10.1186/s12916-021-01902-z)

Prospective association between adherence to the Mediterranean diet and hepatic steatosis: the Swiss CoLaus cohort study.

Khalatbari-Soltani S, Marques-Vidal P, Imamura F, Forouhi NG

BMJ Open Dec 2020

(DOI : 10.1136/bmjopen-2020-040959)

Plasma Sulfur Amino Acids and Risk of Cerebrovascular Diseases: A Nested Case-Control Study in the EPIC-Norfolk Cohort.

Vinknes KJ, Refsum H, Turner C, Khaw KT, Wareham NJ, Forouhi NG, Imamura F

Stroke Dec 2020

(DOI : 10.1161/STROKEAHA.120.029177)

Longitudinal associations between prepubertal childhood total energy and macronutrient intakes and subsequent puberty timing in UK boys and girls.

Cheng TS, Sharp SJ, Brage S, Emmett PM, Forouhi NG, Ong KK

European journal of nutrition Nov 2020

(DOI : 10.1007/s00394-021-02629-6)

Food Sources and Dietary Quality in Small Island Developing States: Development of Methods and Policy Relevant Novel Survey Data from the Pacific and Caribbean.

Haynes E, Bhagtani D, Iese V, Brown CR, Fesaitu J, Hambleton I, Badrie N, Kroll F, Guell C, Brugulat-Panés A, Saint Ville A, Benjamin-Neelon SE, Foley L, Samuels TA, Wairiu M, Forouhi NG, Unwin N, On Behalf Of The Community Food And Health CFaH Team

Nutrients Sep 2020

(DOI : 10.3390/nu12113350)

n-3 Fatty Acid Biomarkers and Incident Type 2 Diabetes: An Individual Participant-Level Pooling Project of 20 Prospective Cohort Studies.

Qian F, Ardisson Korat AV, Imamura F, Marklund M, Tintle N, Virtanen JK, Zhou X, Bassett JK, Lai H, Hirakawa Y, Chien KL, Wood AC, Lankinen M, Murphy RA, Samieri C, Pertiwi K, de Mello VD, Guan W, Forouhi NG, Wareham N, Hu ICFB, Riserus U, Lind L, Harris WS, Shadyab AH, Robinson JG, Steffen LM, Hodge A, Giles GG, Ninomiya T, Uusitupa M, Tuomilehto J, Lindström J, Laakso M, Siscovick DS, Helmer C, Geleijnse JM, Wu JHY, Fretts A, Lemaitre RN, Micha R, Mozaffarian D, Sun Q, Fatty Acids and Outcomes Research Consortium (FORCE)

Diabetes care Sep 2020

(DOI : 10.2337/dc20-2426)

Patterns of multimorbidity and risk of severe SARS-CoV-2 infection: an observational study in the U.K.

Chudasama YV, Zaccardi F, Gillies CL, Razieh C, Yates T, Kloecker DE, Rowlands AV, Davies MJ, Islam N, Seidu S, Forouhi NG, Khunti K

BMC infectious diseases Sep 2020

(DOI : 10.1186/s12879-021-06600-y)

Association between nutritional profiles of foods underlying Nutri-Score front-of-pack labels and mortality: EPIC cohort study in 10 European countries.

Deschasaux M, Huybrechts I, Julia C, Hercberg S, Egnell M, Srour B, Kesse-Guyot E, Latino-Martel P, Biessy C, Casagrande C, Murphy N, Jenab M, Ward HA, Weiderpass E, Overvad K, Tjønneland A, Rostgaard-Hansen AL, Boutron-Ruault MC, Mancini FR, Mahamat-Saleh Y, Kühn T, Katzke V, Bergmann MM, Schulze MB, Trichopoulou A, Karakatsani A, Peppa E, Masala G, Agnoli C, De Magistris MS, Tumino R, Sacerdote C, Boer JM, Verschuren WM, van der Schouw YT, Skeie G, Braaten T, Redondo ML, Agudo A, Petrova D, Colorado-Yohar SM, Barricarte A, Amiano P, Sonestedt E, Ericson U, Otten J, Sundström B, Wareham NJ, Forouhi NG, Vineis P, Tsilidis KK, Knuppel A, Papier K, Ferrari P, Riboli E, Gunter MJ, Touvier M

BMJ (Clinical research ed.) Sep 2020

(DOI : 10.1136/bmj.m3173)

Using nutritional survey data to inform the design of sugar-sweetened beverage taxes in low-resource contexts: a cross-sectional analysis based on data from an adult Caribbean population.

Alvarado M, Harris R, Rose A, Unwin N, Hambleton I, Imamura F, Adams J

BMJ Open Sep 2020

(DOI : 10.1136/bmjopen-2019-035981)

Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies.

Harris WS, Tintle NL, Imamura F, Qian F, Korat AVA, Marklund M, Djoussé L, Bassett JK, Carmichael PH, Chen YY, Hirakawa Y, Küpers LK, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Senn MK, Shi P, Virtanen JK, Brouwer IA, Chien KL, Eiriksdottir G, Forouhi NG, Geleijnse JM, Giles GG, Gudnason V, Helmer C, Hodge A, Jackson R, Khaw KT, Laakso M, Lai H, Laurin D, Leander K, Lindsay J, Micha R, Mursu J, Ninomiya T, Post W, Psaty BM, Riserus U, Robinson JG, Shadyab AH, Snetselaar L, Sala-Vila A, Sun Y, Steffen LM, Tsai MY, Wareham NJ, Wood AC, Wu JHY, Hu F, Sun Q, Siscovick DS, Lemaitre RN, Mozaffarian D, Fatty Acids and Outcomes Research Consortium (FORCE)

Nature communications Aug 2020

(DOI : 10.1038/s41467-021-22370-2)

Associations of Total Legume, Pulse, and Soy Consumption with Incident Type 2 Diabetes: Federated Meta-Analysis of 27 Studies from Diverse World Regions.

Pearce M, Fanidi A, Bishop TRP, Sharp SJ, Imamura F, Dietrich S, Akbaraly T, Bes-Rastrollo M, Beulens JWJ, Byberg L, Canhada S, Molina MDCB, Chen Z, Cortes-Valencia A, Du H, Duncan BB, Härkänen T, Hashemian M, Kim J, Kim MK, Kim Y, Knekt P, Kromhout D, Lassale C, Ridaura RL, Magliano DJ, Malekzadeh R, Marques-Vidal P, Martínez-González MÁ, O'Donoghue G, O'Gorman D, Shaw JE, Soedamah-Muthu SS, Stern D, Wolk A, Woo HW, EPIC-InterAct Consortium, Wareham NJ, Forouhi NG

The Journal of nutrition Aug 2020

(DOI : 10.1093/jn/nxaa447)

Plant foods, dietary fibre and risk of ischaemic heart disease in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

Perez-Cornago A, Crowe FL, Appleby PN, Bradbury KE, Wood AM, Jakobsen MU, Johnson L, Sacerdote C, Steur M, Weiderpass E, Würtz AML, Kühn T, Katzke V, Trichopoulou A, Karakatsani A, La Vecchia C, Masala G, Tumino R, Panico S, Sluijs I, Skeie G, Imaz L, Petrova D, Quirós JR, Yohar SMC, Jakszyn P, Melander O, Sonestedt E, Andersson J, Wennberg M, Aune D, Riboli E, Schulze MB, Di Angelantonio E, Wareham NJ, Danesh J, Forouhi NG, Butterworth AS, Key TJ

International Journal of Epidemiology Jul 2020

(DOI : 10.1093/ije/dyaa155)

Association of plasma biomarkers of fruit and vegetable intake with incident type 2 diabetes: EPIC-InterAct case-cohort study in eight European countries.

Zheng JS, Sharp SJ, Imamura F, Chowdhury R, Gundersen TE, Steur M, Sluijs I, van der Schouw YT, Agudo A, Aune D, Barricarte A, Boeing H, Chirlaque MD, Dorronsoro M, Freisling H, El-Fatouhi D, Franks PW, Fagherazzi G, Grioni S, Gunter MJ, Kyrø C, Katzke V, Kühn T, Khaw KT, Laouali N, Masala G, Nilsson PM, Overvad K, Panico S, Papier K, Quirós JR, Rolandsson O, Redondo-Sánchez D, Ricceri F, Schulze MB, Spijkerman AMW, Tjønneland A, Tong TYN, Tumino R, Weiderpass E, Danesh J, Butterworth AS, Riboli E, Forouhi NG, Wareham NJ

BMJ (Clinical research ed.) Jul 2020

(DOI : 10.1136/bmj.m2194)

Interaction Between GAD65 Antibodies and Dietary Fish Intake or Plasma Phospholipid n-3 Polyunsaturated Fatty Acids on Incident Adult-Onset Diabetes: The EPIC-InterAct Study.

Löfvenborg JE, Carlsson S, Andersson T, Hampe CS, Koulman A, Chirlaque Lopez MD, Jakszyn P, Katzke VA, Kühn T, Kyrø C, Masala G, Nilsson PM, Overvad K, Panico S, Sánchez MJ, van der Schouw Y, Schulze MB, Tjønneland A, Weiderpass E, Riboli E, Forouhi NG, Sharp SJ, Rolandsson O, Wareham NJ

Diabetes care Jun 2020

(DOI : 10.2337/dc20-1463)

Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations.

Zheng JS, Luan J, Sofianopoulou E, Imamura F, Stewart ID, Day FR, Pietzner M, Wheeler E, Lotta LA, Gundersen TE, Amiano P, Ardanaz E, Chirlaque MD, Fagherazzi G, Franks PW, Kaaks R, Laouali N, Mancini FR, Nilsson PM, Onland-Moret NC, Olsen A, Overvad K, Panico S, Palli D, Ricceri F, Rolandsson O, Spijkerman AMW, Sánchez MJ, Schulze MB, Sala N, Sieri S, Tjønneland A, Tumino R, van der Schouw YT, Weiderpass E, Riboli E, Danesh J, Butterworth AS, Sharp SJ, Langenberg C, Forouhi NG, Wareham NJ

Diabetes care Jun 2020

(DOI : 10.2337/dc20-1328)

Mediterranean diet and risk of Sjögren's syndrome.

Machowicz A, Hall I, de Pablo P, Rauz S, Richards A, Higham J, Poveda-Gallego A, Imamura F, Bowman SJ, Barone F, Fisher BA

Clinical and experimental rheumatology May 2020

(DOI : 15905)

Replacement of Red and Processed Meat With Other Food Sources of Protein and the Risk of Type 2 Diabetes in European Populations: The EPIC-InterAct Study.

Ibsen DB, Steur M, Imamura F, Overvad K, Schulze MB, Bendinelli B, Guevara M, Agudo A, Amiano P, Aune D, Barricarte A, Ericson U, Fagherazzi G, Franks PW, Freisling H, Quirós JR, Grioni S, Heath AK, Huybrechts I, Katze V, Laouali N, Mancini F, Masala G, Olsen A, Papier K, Ramne S, Rolandsson O, Sacerdote C, Sánchez MJ, Santiuste C, Simeon V, Spijkerman AMW, Srour B, Tjønneland A, Tong TYN, Tumino R, van der Schouw YT, Weiderpass E, Wittenbecher C, Sharp SJ, Riboli E, Forouhi NG, Wareham NJ

Diabetes care May 2020

(DOI : 10.2337/dc20-1038)

Biomarker-estimated flavan-3-ol intake is associated with lower blood pressure in cross-sectional analysis in EPIC Norfolk.

Ottaviani JI, Britten A, Lucarelli D, Luben R, Mulligan AA, Lentjes MA, Fong R, Gray N, Grace PB, Mawson DH, Tym A, Wierzbicki A, Forouhi NG, Khaw KT, Schroeter H, Kuhnle GGC

Scientific reports Apr 2020

(DOI : 10.1038/s41598-020-74863-7)

Erythrocyte n-6 Polyunsaturated Fatty Acids, Gut Microbiota, and Incident Type 2 Diabetes: A Prospective Cohort Study.

Miao Z, Lin JS, Mao Y, Chen GD, Zeng FF, Dong HL, Jiang Z, Wang J, Xiao C, Shuai M, Gou W, Fu Y, Imamura F, Chen YM, Zheng JS

Diabetes care Mar 2020

(DOI : 10.2337/dc20-0631)

Insights into genetic variants associated with NASH-fibrosis from metabolite profiling.

Mann JP, Pietzner M, Wittemans LB, Rolfe EL, Kerrison ND, Imamura F, Forouhi NG, Fauman E, Allison ME, Griffin JL, Koulman A, Wareham NJ, Langenberg C

Human Molecular Genetics Mar 2020

(DOI : 10.1093/hmg/ddaa162)

A cross-platform approach identifies genetic regulators of human metabolism and health.

Lotta LA, Pietzner M, Stewart ID, Wittemans LBL, Li C, Bonelli R, Raffler J, Biggs EK, Oliver-Williams C, Auyeung VPW, Luan J, Wheeler E, Paige E, Surendran P, Michelotti GA, Scott RA, Burgess S, Zuber V, Sanderson E, Koulman A, Imamura F, Forouhi NG, Khaw KT, MacTel Consortium, Griffin JL, Wood AM, Kastenmüller G, Danesh J, Butterworth AS, Gribble FM, Reimann F, Bahlo M, Fauman E, Wareham NJ, Langenberg C

Nature genetics Feb 2020

(DOI : 10.1038/s41588-020-00751-5)

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar N, Pouta A, Snieder H, Boerwinkle E, Pankow JS, Magnusson PK, Krus U, Scapoli C, de Geus EJCN, Blüher M, Wolffenbuttel BHR, Province MA, Abecasis GR, Meigs JB, Hovingh GK, Lindström J, Wilson JF, Wright AF, Dedoussis GV, Bornstein SR, Schwarz PEH, Tönjes A, Winkelmann BR, Boehm BO, März W, Metspalu A, Price JF, Deloukas P, Körner A, Lakka TA, Keinanen-Kiukaanniemi SM, Saaristo TE, Bergman RN, Tuomilehto J, Wareham NJ, Langenberg C, Männistö S, Franks PW, Hayward C, Vitart V, Kaprio J, Visvikis-Siest S, Balkau B, Altshuler D, Rudan I, Stumvoll M, Campbell H, van Duijn CM, Gieger C, Illig T, Ferrucci L, Pedersen NL, Pramstaller PP, Boehnke M, Frayling TM, Shuldiner AR, Peyser PA, Kardia SLR, Palmer LJ, Penninx BW, Meneton P, Harris TB, Navis G, Harst PV, Smith GD, Forouhi NG, Loos RJF, Salomaa V, Soranzo N, Boomsma DI, Groop L, Tuomi T, Hofman A, Munroe PB, Gudnason V, Siscovick DS, Watkins H, Lecoeur C, Vollenweider P, Franco-Cereceda A, Eriksson P, Järvelin MR, Stefansson K, Hamsten A, Nicholson G, Karpe F, Dermitzakis ET, Lindgren CM, McCarthy MI, Froguel P, Kaakinen MA, Lyssenko V, Watanabe RM, Ingelsson E, Florez JC, Dupuis J, Barroso I, Morris AP, Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nature communications Jan 2020

(DOI : 10.1038/s41467-020-19366-9)

Prospective association of soft drink consumption with depressive symptoms.

Kashino I, Kochi T, Imamura F, Eguchi M, Kuwahara K, Nanri A, Kurotani K, Akter S, Hu H, Miki T, Kabe I, Mizoue T

Nutrition (Burbank, Los Angeles County, Calif.) Dec 2019

(DOI : 10.1016/j.nut.2020.110860)

Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet.

Senftleber N, Jørgensen ME, Jørsboe E, Imamura F, Forouhi NG, Larsen CL, Bjerregaard P, Hansen T, Albrechtsen A

European journal of human genetics : EJHG Dec 2019

(DOI : 10.1038/s41431-020-0674-0)

How do short-term associations between diet quality and metabolic risk vary with age?

Winpenny EM, van Sluijs EMF, Forouhi NG

European journal of nutrition Oct 2019

(DOI : 10.1007/s00394-020-02266-5)

The associations of longitudinal changes in consumption of total and types of dairy products and markers of metabolic risk and adiposity: findings from the European Investigation into Cancer and Nutrition (EPIC)-Norfolk study, United Kingdom.

Trichia E, Luben R, Khaw KT, Wareham NJ, Imamura F, Forouhi NG

The American Journal of Clinical Nutrition Oct 2019

(DOI : 10.1093/ajcn/nqz335)

Fatty acids in the de novo lipogenesis pathway and incidence of type 2 diabetes: A pooled analysis of prospective cohort studies.

Imamura F, Fretts AM, Marklund M, Ardisson Korat AV, Yang WS, Lankinen M, Qureshi W, Helmer C, Chen TA, Virtanen JK, Wong K, Bassett JK, Murphy R, Tintle N, Yu CI, Brouwer IA, Chien KL, Chen YY, Wood AC, Del Gobbo LC, Djoussé L, Geleijnse JM, Giles GG, de Goede J, Gudnason V, Harris WS, Hodge A, Hu F, InterAct Consortium, Koulman A, Laakso M, Lind L, Lin HJ, McKnight B, Rajaobelina K, Riserus U, Robinson JG, Samieri C, Senn M, Siscovick DS, Soedamah-Muthu SS, Sotoodehnia N, Sun Q, Tsai MY, Tuomainen TP, Uusitupa M, Wagenknecht LE, Wareham NJ, Wu JHY, Micha R, Lemaitre RN, Mozaffarian D, Forouhi NG

PLoS Medicine Oct 2019

(DOI : 10.1371/journal.pmed.1003102)

Glycemic index, glycemic load, and risk of coronary heart disease: a pan-European cohort study.

Sieri S, Agnoli C, Grioni S, Weiderpass E, Mattiello A, Sluijs I, Sánchez MJ, Jakobsen MU, Sweeting M, van der Schouw YT, Nilsson LM, Wennberg P, Katzke VA, Kühn T, Overvad K, Tong TYN, Conchi MI, Quirós JR, García-Torrecillas JM, Mokoroa O, Gómez JH, Tjønneland A, Sonestedt E, Trichopoulou A, Karakatsani A, Valanou E, Boer JMA, Verschuren WMM, Boutron-Ruault MC, Fagherazzi G, Madika AL, Bergmann MM, Schulze MB, Ferrari P, Freisling H, Lennon H, Sacerdote C, Masala G, Tumino R, Riboli E, Wareham NJ, Danesh J, Forouhi NG, Butterworth AS, Krogh V

The American Journal of Clinical Nutrition Oct 2019

(DOI : 10.1093/ajcn/nqaa157)

The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.

Zheng JS, Luan J, Sofianopoulou E, Sharp SJ, Day FR, Imamura F, Gundersen TE, Lotta LA, Sluijs I, Stewart ID, Shah RL, van der Schouw YT, Wheeler E, Ardanaz E, Boeing H, Dorronsoro M, Dahm CC, Dimou N, El-Fatouhi D, Franks PW, Fagherazzi G, Grioni S, Huerta JM, Heath AK, Hansen L, Jenab M, Jakszyn P, Kaaks R, Kühn T, Khaw KT, Laouali N, Masala G, Nilsson PM, Overvad K, Olsen A, Panico S, Quirós JR, Rolandsson O, Rodriguez-Barranco M, Sacerdote C, Spijkerman AMW, Tong TYN, Tumino R, Tsilidis KK, Danesh J, Riboli E, Butterworth AS, Langenberg C, Forouhi NG, Wareham NJ

PLoS Medicine Sep 2019

(DOI : 10.1371/journal.pmed.1003394)

Descriptive epidemiology of physical activity energy expenditure in UK adults (The Fenland study).

Lindsay T, Westgate K, Wijndaele K, Hollidge S, Kerrison N, Forouhi N, Griffin S, Wareham N, Brage S

The international journal of behavioral nutrition and physical activity Aug 2019

(DOI : 10.1186/s12966-019-0882-6)

Evaluation of (-)-epicatechin metabolites as recovery biomarker of dietary flavan-3-ol intake.

Ottaviani JI, Fong R, Kimball J, Ensunsa JL, Gray N, Vogiatzoglou A, Britten A, Lucarelli D, Luben R, Grace PB, Mawson DH, Tym A, Wierzbicki A, Wareham NJ, Forouhi NG, Khaw KT, Schroeter H, Kuhnle GGC

Scientific reports Jul 2019

(DOI : 10.1038/s41598-019-49702-z)

Associations of types of dairy consumption with adiposity: cross-sectional findings from over 12,000 adults in the Fenland Study, UK.

Trichia E, Imamura F, Brage S, De Lucia Rolfe E, Griffin SJ, Wareham NJ, Forouhi NG

The British journal of nutrition Jul 2019

(DOI : 10.1017/S0007114519001776)

A Combination of Metabolites Predicts Adherence to the Mediterranean Diet Pattern and Its Associations with Insulin Sensitivity and Lipid Homeostasis in the General Population: The Fenland Study, United Kingdom.

Tong TYN, Koulman A, Griffin JL, Wareham NJ, Forouhi NG, Imamura F

The Journal of nutrition Jun 2019

(DOI : 10.1093/jn/nxz263)

The associations of major foods and fibre with risks of ischaemic and haemorrhagic stroke: a prospective study of 418 329 participants in the EPIC cohort across nine European countries.

Tong TYN, Appleby PN, Key TJ, Dahm CC, Overvad K, Olsen A, Tjønneland A, Katzke V, Kühn T, Boeing H, Karakatsani A, Peppa E, Trichopoulou A, Weiderpass E, Masala G, Grioni S, Panico S, Tumino R, Boer JMA, Verschuren WMM, Quirós JR, Agudo A, Rodriguez-Barranco M, Imaz L, Chirlaque MD, Moreno-Iribas C, Engström G, Sonestedt E, Lind M, Otten J, Khaw KT, Aune D, Riboli E, Wareham NJ, Imamura F, Forouhi NG, Di Angelantonio E, Wood AM, Butterworth AS, Perez-Cornago A

European heart journal Jun 2019

(DOI : 10.1093/eurheartj/ehaa007)

Nutritional adequacy and dietary disparities in an adult Caribbean population of African descent with a high burden of diabetes and cardiovascular disease.

Harris RM, Rose AMC, Forouhi NG, Unwin N

Food science & nutrition Jun 2019

(DOI : 10.1002/fsn3.1363)

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.

Marklund M, Wu JHY, Imamura F, Del Gobbo LC, Fretts A, de Goede J, Tintle N, Wennberg M, Aslibekyan S, Chen TA, de Oliveira Otto MC, Kröger J, Laguzzi F, Lankinen M, Murphy RA, Samieri C, Wood AC, Wong K, Yang WS, Zhou X, Boer JMA, Brouwer IA, Chien KL, de Faire U, Djoussé L, Eiriksdottir G, Forouhi NG, Geleijnse JM, Gigante B, Gudnason V, Harris WS, Helmer C, Hodge A, Jansson JH, Kalsbeek A, Khaw KT, Koh WP, Laakso M, Leander K, Lin HJ, Lind L, Luben R, McKnight B, Ninomiya T, Overvad K, Psaty BM, Schulze MB, Siscovick D, Smith AV, Steffen BT, Sundström J, Tsai MY, van Dam RM, Veenstra J, Wareham NJ, Woodward M, Yuan JM, Micha R, Lemaitre RN, Mozaffarian D, Riserus U

Circulation May 2019

(DOI : 10.1161/CIRCULATIONAHA.118.038908)

What principles should guide interactions between population health researchers and the food industry? Systematic scoping review of peer-reviewed and grey literature.

Cullerton K, Adams J, Forouhi N, Francis O, White M

Obesity reviews : an official journal of the International Association for the Study of Obesity Apr 2019

(DOI : 10.1111/obr.12851)

Validity and reliability of an online self-report 24-h dietary recall method (Intake24): a doubly labelled water study and repeated-measures analysis.

Foster E, Lee C, Imamura F, Hollidge SE, Westgate KL, Venables MC, Poliakov I, Rowland MK, Osadchiy T, Bradley JC, Simpson EL, Adamson AJ, Olivier P, Wareham N, Forouhi NG, Brage S

Journal of nutritional science Apr 2019

(DOI : 10.1017/jns.2019.20)

Driving status, travel modes and accelerometer-assessed physical activity in younger, middle-aged and older adults: a prospective study of 90 810 UK Biobank participants.

Hajna S, White T, Panter J, Brage S, Wijndaele K, Woodcock J, Ogilvie D, Imamura F, Griffin SJ

International Journal of Epidemiology Mar 2019

(DOI : 10.1093/ije/dyz065)

Estimated Substitution of Tea or Coffee for Sugar-Sweetened Beverages Was Associated with Lower Type 2 Diabetes Incidence in Case-Cohort Analysis across 8 European Countries in the EPIC-InterAct Study.

Imamura F, Schulze MB, Sharp SJ, Guevara M, Romaguera D, Bendinelli B, Salamanca-Fernández E, Ardanaz E, Arriola L, Aune D, Boeing H, Dow C, Fagherazzi G, Franks PW, Freisling H, Jakszyn P, Kaaks R, Khaw KT, Kühn T, Mancini FR, Masala G, Chirlaque MD, Nilsson PM, Overvad K, Pala VM, Panico S, Perez-Cornago A, Quirós JR, Ricceri F, Rodriguez-Barranco M, Rolandsson O, Sluijs I, Stepien M, Spijkerman AMW, Tjønneland A, Tong TYN, Tumino R, Vissers LET, Ward HA, Langenberg C, Riboli E, Forouhi NG, Wareham NJ

The Journal of nutrition Feb 2019

(DOI : 10.1093/jn/nxz156)

Differential effects of oral boluses of vitamin D2 versus vitamin D3 on vitamin D metabolism: a randomized controlled trial.

Martineau AR, Thummel KE, Wang Z, Jolliffe DA, Boucher BJ, Griffin SJ, Forouhi NG, Hitman GA

The Journal of clinical endocrinology and metabolism Jan 2019

(DOI : 10.1210/jc.2019-00207)

Association of alcohol consumption with prevalence of fatty liver after adjustment for dietary patterns: Cross-sectional analysis of Japanese middle-aged adults.

Tajima R, Imamura F, Kimura T, Kobayashi S, Masuda K, Iida K

Clinical nutrition (Edinburgh, Scotland) Jan 2019

(DOI : 10.1016/j.clnu.2019.07.001)

Changes in plasma phospholipid fatty acid profiles over 13 years and correlates of change: European Prospective Investigation into Cancer and Nutrition-Norfolk Study.

Zheng JS, Imamura F, Sharp SJ, Koulman A, Griffin JL, Mulligan AA, Luben R, Khaw KT, Wareham NJ, Forouhi NG

The American Journal of Clinical Nutrition Dec 2018

(DOI : 10.1093/ajcn/nqz030)

Autoimmunity plays a role in the onset of diabetes after 40 years of age.

Rolandsson O, Hampe CS, Sharp SJ, Ardanaz E, Boeing H, Fagherazzi G, Mancini FR, Nilsson PM, Overvad K, Chirlaque MD, Dorronsoro M, Gunter MJ, Kaaks R, Key TJ, Khaw KT, Krogh V, Kühn T, Palli D, Panico S, Sacerdote C, Sánchez MJ, Severi G, Spijkerman AMW, Tumino R, van der Schouw YT, Riboli E, Forouhi NG, Langenberg C, Wareham NJ

Diabetologia Dec 2018

(DOI : 10.1007/s00125-019-05016-3)

The obesity transition: stages of the global epidemic.

Jaacks LM, Vandevijvere S, Pan A, McGowan CJ, Wallace C, Imamura F, Mozaffarian D, Swinburn B, Ezzati M

The lancet. Diabetes & endocrinology Dec 2018

(DOI : 10.1016/S2213-8587(19)30026-9)

Anthropometric and reproductive factors and risk of esophageal and gastric cancer by subtype and subsite: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

Sanikini H, Muller DC, Sophiea M, Rinaldi S, Agudo A, Duell EJ, Weiderpass E, Overvad K, Tjønneland A, Halkjaer J, Boutron-Ruault MC, Carbonnel F, Cervenka I, Boeing H, Kaaks R, Kühn T, Trichopoulou A, Martimianaki G, Karakatsani A, Pala V, Palli D, Mattiello A, Tumino R, Sacerdote C, Skeie G, Rylander C, Chirlaque Lopez MD, Sánchez MJ, Ardanaz E, Regnér S, Stocks T, Bueno-de-Mesquita B, Vermeulen RCH, Aune D, Tong TYN, Kliemann N, Murphy N, Chadeau-Hyam M, Gunter MJ, Cross AJ

International journal of cancer Nov 2018

(DOI : 10.1002/ijc.32386)

Study at Cambridge

About the University

Research at Cambridge