MRC Epidemiology Unit

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programme => Nutrition Measurement Platform

The validation of an LC-MS/MS method for the quantification of vitamin D metabolites in human milk and their biological variability in Gambian women.

Jones KS, Meadows SR, Billing G, Koulman A, Prentice A

The Journal of steroid biochemistry and molecular biology Nov 2024

(DOI : 10.1016/j.jsbmb.2024.106633)

Effects of coconut oil, olive oil, and butter on plasma fatty acids and metabolic risk factors: a randomized trial.

Sowah SA, Koulman A, Sharp SJ, Imamura F, Khaw KT, Forouhi NG

Journal of lipid research Nov 2024

(DOI : 10.1016/j.jlr.2024.100681)

Prediction of total and regional body composition from 3D body shape.

Qiao C, Rolfe EL, Mak E, Sengupta A, Powell R, Watson LPE, Heymsfield SB, Shepherd JA, Wareham N, Brage S, Cipolla R

NPJ digital medicine Oct 2024

(DOI : 10.1038/s41746-024-01289-0)

Combined associations of physical activity, diet quality and their changes over time with mortality: findings from the EPIC-Norfolk study, United Kingdom.

Aryannezhad S, Mok A, Imamura F, Wareham NJ, Brage S, Forouhi NG

BMC medicine Oct 2024

(DOI : 10.1186/s12916-024-03668-6)

Associations of takeaway outlets with takeaway food consumption and adiposity: longitudinal analysis of the Fenland cohort.

Hoenink JC, Burgoine T, Forouhi NG, Monsivais P, Sharp SJ, Panter J, Adams J

Obesity (Silver Spring, Md.) Oct 2024

(DOI : 10.1002/oby.24152)

Systems Approach to Investigate the Role of Fruit and Vegetable Types on Vascular Function in Pre-Hypertensive Participants: Protocol and Baseline Characteristics of a Randomised Crossover Dietary Intervention.

Oude Griep LM, Frost G, Holmes E, Wareham NJ, Elliott P

Nutrients Sep 2024

(DOI : 10.3390/nu16172923)

Disaggregation of Dairy in Composite Foods in the United Kingdom.

Jaacks LM, Amoutzopoulos B, Runions R, Vonderschmidt A, McNeill G, Comrie F, McDonald A, Page P, Stewart C

Current developments in nutrition Aug 2024

(DOI : 10.1016/j.cdnut.2024.103774)

The effect of an acute bout of exercise on circulating vitamin D metabolite concentrations: a randomised crossover study in healthy adults.

Davies SE, Perkin OJ, Betts JA, Gonzalez JT, Hewison M, Jenkinson C, Jones KS, Meadows SR, Parkington DA, Koulman A, Thompson D

The Journal of physiology Aug 2024

(DOI : 10.1113/JP286395)

Digital Intervention Promoting Physical Activity in People Newly Diagnosed with Parkinson's Disease: Feasibility and Acceptability of the Knowledge, Exercise-Efficacy and Participation (KEEP) Intervention.

Agley L, Hartley P, Duffill D, Iqbal A, Mackett A, Rennie KL, Lafortune L

Journal of Parkinson's disease Aug 2024

(DOI : 10.3233/JPD-240071)

The Impact of Delayed Processing of Chilled Whole Blood Specimens on the Measurement of Nutritional Biomarkers in the United Kingdom National Diet and Nutrition Survey Rolling Programme.

Jones KS, Meadows SR, Parkington DA, Collins D, Bates B, Koulman A, Page P

The Journal of nutrition Jul 2024

(DOI : 10.1016/j.tjnut.2024.07.008)

Assessment of Erythrocyte Transketolase, Whole Blood Thiamine Diphosphate, and Human Milk Thiamine Concentrations to Identify Infants and Young Children Responding Favorably to Therapeutic Thiamine Administration: Findings from the Lao Thiamine Study, a Prospective Cohort Study.

Hess SY, Smith TJ, Arnold CD, Jones KS, Hampel D, Hiffler L, Trehan I, Fischer PR, Meadows SR, Parkington DA, Brown KH, Sitthideth D, Tan X, Koulman A, Allen LH, Kounnavong S

Current developments in nutrition Jul 2024

(DOI : 10.1016/j.cdnut.2024.103786)

Protocol for a seamless phase 2A-phase 2B randomized double-blind placebo-controlled trial to evaluate the safety and efficacy of benfotiamine in patients with early Alzheimer's disease (BenfoTeam).

Feldman HH, Luchsinger JA, Léger GC, Taylor C, Jacobs DM, Salmon DP, Edland SD, Messer K, Revta C, Flowers SA, Jones KS, Koulman A, Yarasheski KE, Verghese PB, Venkatesh V, Zetterberg H, Durant J, Lupo JL, Gibson GE, ADCS BenfoTeam Study Group ADCS BenfoTeam Study Group

PLoS ONE May 2024

(DOI : 10.1371/journal.pone.0302998)

Associations of Systematic Inflammatory Markers with Diet Quality, Blood Pressure, and Obesity in the AIRWAVE Health Monitoring Study.

Aljuraiban GS, Gibson R, Oude Griep LM

Journal of inflammation research May 2024

(DOI : 10.2147/JIR.S459238)

Assessing Performance of Contemporary Plant-Based Diets against the UK Dietary Guidelines: Findings from the Feeding the Future (FEED) Study.

Lawson I, Wood C, Syam N, Rippin H, Dagless S, Wickramasinghe K, Amoutzopoulos B, Steer T, Key TJ, Papier K

Nutrients May 2024

(DOI : 10.3390/nu16091336)

Early outcomes of referrals to the English National Health Service Digital Weight Management Programme.

Taylor K, Indulkar T, Thompson B, Pinkard C, Barron E, Frost T, Jayawardane P, Davies N, Bakhai C, Forouhi NG, Aveyard P, Jebb S, Valabhji J

Obesity (Silver Spring, Md.) Apr 2024

(DOI : 10.1002/oby.24024)

Diet and physical activity interventions to improve cardiovascular disease risk factors in liver transplant recipients: Systematic review and meta-analysis.

Spillman LN, Stowe E, Madden AM, Rennie KL, Oude Griep LM, Allison M, Kenney L, O'Connor C, Griffin SJ

Transplantation reviews (Orlando, Fla.) Apr 2024

(DOI : 10.1016/j.trre.2024.100852)

Dual glucagon-like peptide-1 and glucagon receptor agonism reduces energy intake in type 2 diabetes with obesity.

Golubic R, Kennet J, Parker V, Robertson D, Luo D, Hansen L, Jermutus L, Ambery P, Ryaboshapkina M, Surakala M, Laker RC, Venables M, Koulman A, Park A, Evans M

Diabetes, obesity & metabolism Apr 2024

(DOI : 10.1111/dom.15579)

A Self-Paced Walk Test for Individual Calibration of Heart Rate to Energy Expenditure

Westgate K, Gonzales TI, Hollidge S, Lindsay T, Wareham N, Brage S

Journal for the Measurement of Physical Behaviour Mar 2024

(DOI : 10.1123/jmpb.2023-0042)

Sex differences in energy balance, body composition, and metabolic and endocrine markers during prolonged arduous military training.

O'Leary TJ, Gifford RM, Knight RL, Wright J, Handford S, Venables MC, Reynolds RM, Woods D, Wardle SL, Greeves JP

Journal of applied physiology (Bethesda, Md. : 1985) Feb 2024

(DOI : 10.1152/japplphysiol.00864.2023)

A Predictive Model for Thiamine Responsive Disorders among Infants and Young Children: Results from a Prospective Cohort Study in Lao People's Democratic Republic.

Smith TJ, Arnold CD, Fischer PR, Trehan I, Hiffler L, Sitthideth D, Stein-Wexler R, Yeh J, Jones KS, Hampel D, Tancredi DJ, Schick MA, McBeth CN, Tan X, Allen LH, Sayasone S, Kounnavong S, Hess SY

The Journal of pediatrics Feb 2024

(DOI : 10.1016/j.jpeds.2024.113961)

Weight gain during nutritional rehabilitation post-childhood malnutrition may influence the associations between adulthood desaturases activity and anthro-cardiometabolic risk factors.

Olga L, McKenzie K, Kerac M, Boyne M, Badaloo A, Bandsma RHJ, Koulman A, Thompson DS

Clinical nutrition (Edinburgh, Scotland) Feb 2024

(DOI : 10.1016/j.clnu.2024.01.032)

The relationship of within-individual and between-individual variation in mental health with bodyweight: An exploratory longitudinal study.

Mueller J, Ahern AL, Jones RA, Sharp SJ, Davies A, Zuckerman A, Perry BI, Khandaker GM, Rolfe EL, Wareham NJ, Rennie KL

PLoS ONE Jan 2024

(DOI : 10.1371/journal.pone.0295117)

Relationship of calcium and magnesium intakes with the dietary approaches to stop hypertension score and blood pressure: the International Study of Macro/micronutrients and Blood Pressure.

Gibson R, Aljuraiban GS, Oude-Griep LM, Vu TH, Steffen LM, Appel LJ, Rodriguez BL, Daviglus ML, Elliott P, Van Horn L, Chan Q

Journal of hypertension Jan 2024

(DOI : 10.1097/HJH.0000000000003648)

Plasma Metabolites Related to the Consumption of Different Types of Dairy Products and Their Association with New-Onset Type 2 Diabetes: Analyses in the Fenland and EPIC-Norfolk Studies, United Kingdom.

Trichia E, Koulman A, Stewart ID, Brage S, Griffin SJ, Griffin JL, Khaw KT, Langenberg C, Wareham NJ, Imamura F, Forouhi NG

Molecular nutrition & food research Dec 2023

(DOI : 10.1002/mnfr.202300154)

Quantification and reporting of vitamin D concentrations measured in human milk by LC-MS/MS.

Jones KS, Meadows SR, Koulman A

Frontiers in nutrition Nov 2023

(DOI : 10.3389/fnut.2023.1229445)

National Diet and Nutrition Survey data reveal a decline in folate status in the UK population between 2008 and 2019.

Jones KS, Collins D, Meadows SR, Koulman A, Page P

The American Journal of Clinical Nutrition Oct 2023

(DOI : 10.1016/j.ajcnut.2023.10.006)

Validation of the Fatty Liver Index for identifying non-alcoholic fatty liver disease in a Kenyan population.

Lajeunesse-Trempe F, Boit MK, Kaduka LU, de Lucia-Rolfe E, Baass A, Paquette M, Piché ME, Tchernof A, Christensen DL

Tropical medicine & international health : TM & IH Aug 2023

(DOI : 10.1111/tmi.13927)

A randomised study of nurse collected venous blood and self-collected dried blood spots for the assessment of cardiovascular risk factors in the Understanding Society Innovation Panel.

Kumari M, Andrayas A, Al Baghal T, Burton J, Crossley TF, Jones KS, Parkington DA, Koulman A, Benzeval M

Scientific reports Aug 2023

(DOI : 10.1038/s41598-023-39674-6)

Faster rehabilitation weight gain during childhood is associated with risk of non-communicable disease in adult survivors of severe acute malnutrition.

Thompson DS, McKenzie K, Opondo C, Boyne MS, Lelijveld N, Wells JC, Cole TJ, Anujuo K, Abera M, Berhane M, Koulman A, Wootton SA, Kerac M, Badaloo A, CHANGE Study Collaborators Group CHANGE Study Collaborators Group

PLOS global public health Jul 2023

(DOI : 10.1371/journal.pgph.0002698)

Omega-3 Fatty Acid Biomarkers and Incident Atrial Fibrillation.

Qian F, Tintle N, Jensen PN, Lemaitre RN, Imamura F, Feldreich TR, Nomura SO, Guan W, Laguzzi F, Kim E, Virtanen JK, Steur M, Bork CS, Hirakawa Y, O'Donoghue ML, Sala-Vila A, Ardisson Korat AV, Sun Q, Rimm EB, Psaty BM, Heckbert SR, Forouhi NG, Wareham NJ, Marklund M, Riserus U, Lind L, Ärnlöv J, Garg P, Tsai MY, Pankow J, Misialek JR, Gigante B, Leander K, Pester JA, Albert CM, Kavousi M, Ikram A, Voortman T, Schmidt EB, Ninomiya T, Morrow DA, Bayés-Genís A, O'Keefe JH, Ong KL, Wu JHY, Mozaffarian D, Harris WS, Siscovick DS, Fatty Acids and Outcomes Research Consortium (FORCE) Fatty Acids and Outcomes Research Consortium (FORCE)

Journal of the American College of Cardiology Jul 2023

(DOI : 10.1016/j.jacc.2023.05.024)

Feasibility of using intermittent active monitoring of vital signs by smartphone users to predict SARS-CoV-2 PCR positivity.

Dolezalova N, Gkrania-Klotsas E, Morelli D, Moore A, Cunningham AC, Booth A, Plans D, Reed AB, Aral M, Rennie KL, Wareham NJ

Scientific reports Jun 2023

(DOI : 10.1038/s41598-023-37301-y)

Associations between change in physical activity and sedentary time and health-related quality of life in older english adults: the EPIC-Norfolk cohort study.

Yerrakalva D, Hajna S, Suhrcke M, Wijndaele K, Westgate K, Khaw KT, Wareham N, Brage S, Griffin S

Health and quality of life outcomes Jun 2023

(DOI : 10.1186/s12955-023-02137-7)

Interaction between plasma phospholipid odd-chain fatty acids and GAD65 autoantibodies on the incidence of adult-onset diabetes: the EPIC-InterAct case-cohort study.

Lampousi AM, Carlsson S, Löfvenborg JE, Cabrera-Castro N, Chirlaque MD, Fagherazzi G, Franks PW, Hampe CS, Jakszyn P, Koulman A, Kyrø C, Moreno-Iribas C, Nilsson PM, Panico S, Papier K, van der Schouw YT, Schulze MB, Weiderpass E, Zamora-Ros R, Forouhi NG, Sharp SJ, Rolandsson O, Wareham NJ

Diabetologia Jun 2023

(DOI : 10.1007/s00125-023-05948-x)

Nutritional Intake after Liver Transplant: Systematic Review and Meta-Analysis.

Spillman LN, Madden AM, Richardson H, Imamura F, Jones D, Nash M, Lim HK, Hellawell HN, Rennie KL, Oude Griep LM, Allison M, Griffin SJ

Nutrients Jun 2023

(DOI : 10.3390/nu15112487)

Resistance to thyroid hormone induced tachycardia in RTHα syndrome.

Dore R, Watson L, Hollidge S, Krause C, Sentis SC, Oelkrug R, Geißler C, Johann K, Pedaran M, Lyons G, Lopez-Alcantara N, Resch J, Sayk F, Iwen KA, Franke A, Boysen TJ, Dalley JW, Lorenz K, Moran C, Rennie KL, Arner A, Kirchner H, Chatterjee K, Mittag J

Nature communications Jun 2023

(DOI : 10.1038/s41467-023-38960-1)

Resting heart rate is a population-level biomarker of cardiorespiratory fitness: The Fenland Study.

Gonzales TI, Jeon JY, Lindsay T, Westgate K, Perez-Pozuelo I, Hollidge S, Wijndaele K, Rennie K, Forouhi N, Griffin S, Wareham N, Brage S

PLoS ONE May 2023

(DOI : 10.1371/journal.pone.0285272)

Energy expenditure and intensity of ritual jumping-dancing in male Maasai.

Christensen DL, Westgate K, Griffiths L, Sironga J, Maro VP, Helge JW, Larsen S, Bygbjerg IC, Ramaiya KL, Jensen J, Brage S

American journal of human biology : the official journal of the Human Biology Council May 2023

(DOI : 10.1002/ajhb.23907)

A randomized, controlled trial of a Nordic, protein-reduced complementary diet in infants: effects on body composition, growth, biomarkers, and dietary intake at 12 and 18 months.

Johansson U, Öhlund I, Lindberg L, Hernell O, Lönnerdal B, Venables M, Lind T

The American Journal of Clinical Nutrition Mar 2023

(DOI : 10.1016/j.ajcnut.2023.03.020)

Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study.

Shannon OM, Ranson JM, Gregory S, Macpherson H, Milte C, Lentjes M, Mulligan A, McEvoy C, Griffiths A, Matu J, Hill TR, Adamson A, Siervo M, Minihane AM, Muniz-Tererra G, Ritchie C, Mathers JC, Llewellyn DJ, Stevenson E

BMC medicine Mar 2023

(DOI : 10.1186/s12916-023-02772-3)

Lifestyle Score and Risk of Hypertension in the Airwave Health Monitoring Study of British Police Force Employees.

Aljuraiban GS, Gibson R, Chan DSM, Elliott P, Chan Q, Griep LMO

International Journal of Environmental Research and Public Health Mar 2023

(DOI : 10.3390/ijerph20054029)

Effect of nationwide school policy on device-measured physical activity in Danish children and adolescents: a natural experiment.

Pedersen NH, Grøntved A, Brønd JC, Møller NC, Larsen KT, Debrabant B, Koch S, Troelsen J, Brage S, Schipperijn J, Hjelmborg J, Wedderkopp N, Christiansen LB, Kristensen PL

The Lancet regional health. Europe Mar 2023

(DOI : 10.1016/j.lanepe.2022.100575)

Cross-sectional and longitudinal associations between the 24-hour movement behaviours, including muscle and bone strengthening activity, with bone and lean mass from childhood to adolescence.

Skinner AM, Barker AR, Moore SA, Soininen S, Haapala EA, Väistö J, Westgate K, Brage S, Lakka TA, Vlachopoulos D

BMC Public Health Mar 2023

(DOI : 10.1186/s12889-024-17711-x)

Centile reference chart for resting metabolic rate through the life course.

Watson L, Cole TJ, Lyons G, Georgiou C, Worsley J, Carr K, Murgatroyd P, Moran C, Chatterjee K, Venables M

Archives of Disease in Childhood Mar 2023

(DOI : 10.1136/archdischild-2022-325249)

Cardiorespiratory Optimisation By Arteriovenous fistula Ligation after renal Transplantation (COBALT): study protocol for a multicentre randomised interventional feasibility trial.

Surendrakumar V, Aitken E, Mark P, Motallebzadeh R, Hunter J, Amer A, Summers D, Rennie K, Rooshenas L, Garbi M, Sylvester K, Hudson C, Banks J, Sidders A, Norton A, Slater M, Bartlett M, Knight S, Pettigrew G

BMJ Open Feb 2023

(DOI : 10.1136/bmjopen-2022-067668)

Shorter sleep among adolescents is associated with lower fruit and vegetable consumption the following day.

Winpenny EM, Rowthorn H, Hollidge S, Westgate K, Goodyer IM, Brage S, van Sluijs EMF

The international journal of behavioral nutrition and physical activity Feb 2023

(DOI : 10.1186/s12966-023-01420-6)

Protocol and application of basal erythrocyte transketolase activity to improve assessment of thiamine status.

Jones KS, Parkington DA, Bourassa MW, Cerami C, Koulman A

Annals of the New York Academy of Sciences Jan 2023

(DOI : 10.1111/nyas.14962)

Worldwide associations of fruit and vegetable supply with blood pressure from 1975 to 2015: an ecological study

Oude Griep LM, Bentham J, Mahadevan P

BMJ nutrition, prevention & health Jan 2023

(DOI : 10.1136/bmjnph-2022-000455)

Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults.

Strain T, Dempsey PC, Wijndaele K, Sharp SJ, Kerrison N, Gonzales TI, Li C, Wheeler E, Langenberg C, Brage S, Wareham N

Diabetes care Jan 2023

(DOI : 10.2337/dc22-1467)

Association between classes and subclasses of polyphenol intake and 5-year body weight changes in the EPIC-PANACEA study.

Castañeda J, Gil-Lespinard M, Almanza-Aguilera E, Llaha F, Gómez JH, Bondonno N, Tjønneland A, Overvad K, Katzke V, Schulze MB, Masala G, Agnoli C, Santucci De Magistris M, Tumino R, Sacerdote C, Skeie G, Brustad M, Lasheras C, Molina-Montes E, Chirlaque MD, Barricarte A, Sonestedt E, da Silva M, Johansson I, Hultdin J, May AM, Forouhi NG, Heath AK, Freisling H, Weiderpass E, Scalbert A, Zamora-Ros R

Obesity (Silver Spring, Md.) Jan 2023

(DOI : 10.1002/oby.23689)

The association between plasma zinc concentrations and markers of glucose metabolism in adults in Cameroon.

Mba CM, Jones KS, Forouhi NG, Imamura F, Assah F, Mbanya JC, Wareham NJ

The British journal of nutrition Jan 2023

(DOI : 10.1017/S0007114523000223)

Dietary Intake of 91 Individual Polyphenols and 5-Year Body Weight Change in the EPIC-PANACEA Cohort.

Gil-Lespinard M, Castañeda J, Almanza-Aguilera E, Gómez JH, Tjønneland A, Kyrø C, Overvad K, Katzke V, Schulze MB, Masala G, Agnoli C, Santucci De Magistris M, Tumino R, Sacerdote C, Skeie G, Lasheras C, Molina-Montes E, Huerta JM, Barricarte A, Amiano P, Sonestedt E, da Silva M, Johansson I, Hultdin J, May AM, Forouhi NG, Heath AK, Freisling H, Weiderpass E, Scalbert A, Zamora-Ros R

Antioxidants (Basel, Switzerland) Dec 2022

(DOI : 10.3390/antiox11122425)

The Childhood Acute Illness and Nutrition (CHAIN) network nested case-cohort study protocol: a multi-omics approach to understanding mortality among children in sub-Saharan Africa and South Asia.

Njunge JM, Tickell K, Diallo AH, Sayeem Bin Shahid ASM, Gazi MA, Saleem A, Kazi Z, Ali S, Tigoi C, Mupere E, Lancioni CL, Yoshioka E, Chisti MJ, Mburu M, Ngari M, Ngao N, Gichuki B, Omer E, Gumbi W, Singa B, Bandsma R, Ahmed T, Voskuijl W, Williams TN, Macharia A, Makale J, Mitchel A, Williams J, Gogain J, Janjic N, Mandal R, Wishart DS, Wu H, Xia L, Routledge M, Gong YY, Espinosa C, Aghaeepour N, Liu J, Houpt E, Lawley TD, Browne H, Shao Y, Rwigi D, Kariuki K, Kaburu T, Uhlig HH, Gartner L, Jones K, Koulman A, Walson J, Berkley J

Gates open research Nov 2022

(DOI : 10.12688/gatesopenres.13635.2)

Rationalisation of the UK Nutrient Databank for Incorporation in a Web-Based Dietary Recall for Implementation in the UK National Diet and Nutrition Survey Rolling Programme.

Amoutzopoulos B, Steer T, Roberts C, Collins D, Trigg K, Barratt R, Abraham S, Cole DJ, Mulligan A, Foreman J, Farooq A, Page P

Nutrients Nov 2022

(DOI : 10.3390/nu14214551)

Physical activity volume and intensity distribution in relation to bone, lean and fat mass in children.

Skinner AM, Vlachopoulos D, Barker AR, Moore SA, Rowlands AV, Soininen S, Haapala EA, Väistö J, Westgate K, Brage S, Lakka TA

Scandinavian journal of medicine & science in sports Nov 2022

(DOI : 10.1111/sms.14255)

Physical Activity Volume, Intensity and Incident Cardiovascular Disease.

Dempsey PC, Rowlands AV, Strain T, Zaccardi F, Dawkins N, Razieh C, Davies MJ, Khunti KK, Edwardson CL, Wijndaele K, Brage S, Yates T

European heart journal Oct 2022

(DOI : 10.1093/eurheartj/ehac613)

Descriptive Epidemiology of Cardiorespiratory Fitness in UK Adults: The Fenland Study.

Gonzales TI, Westgate K, Hollidge S, Lindsay T, Wijndaele K, Forouhi NG, Griffin S, Wareham N, Brage S

Medicine and Science in Sports and Exercise Oct 2022

(DOI : 10.1249/MSS.0000000000003068)

Factors Associated with Significant Weight Loss in Hospitalised Patients with COVID-19: A Retrospective Cohort Study in a Large Teaching Hospital.

Zannidi D, Patel PS, Leventea E, Paciepnik J, Dobson F, Heyes C, Goudie RJB, Griep LMO, Preller J, Spillman LN

Nutrients Oct 2022

(DOI : 10.3390/nu14194195)

Engagement with mHealth COVID-19 digital biomarker measurements in a longitudinal cohort study: a mixed methods evaluation.

Rennie KL, Lawlor ER, Yassaee A, Booth A, Westgate K, Sharp SJ, Tyrrell CS, Aral M, Wareham NJ

Journal of medical Internet research Oct 2022

(DOI : 10.2196/40602)

Lipid profiling analyses from mouse models and human infants.

Olga L, Bobeldijk-Pastorova I, Bas RC, Seidel F, Snowden SG, Furse S, Ong KK, Kleemann R, Koulman A

STAR protocols Sep 2022

(DOI : 10.1016/j.xpro.2022.101679)

An investigation of factors affecting changes in health behaviours during the COVID-19 pandemic in a UK population-based cohort study

Braithwaite VS, Sharp SJ, Koulman A, Wareham N, Rennie KL

Public Health Sep 2022

(DOI : 10.1016/j.puhe.2022.08.005)

Towards harmonization of directly measured free 25-hydroxyvitamin D using an enzyme-linked immunosorbent assay.

Sempos CT, Lindhout E, Heureux N, Hars M, Parkington DA, Dennison E, Durazo-Arvizu R, Jones KS, Wise SA

Analytical and bioanalytical chemistry Sep 2022

(DOI : 10.1007/s00216-022-04313-y)

Evaluation of the New Individual Fatty Acid Dataset for UK Biobank: Analysis of Intakes and Sources in 207,997 Participants.

Kelly RK, Pollard Z, Young H, Piernas C, Lentjes M, Mulligan A, Huybrechts I, Carter JL, Key TJ, Perez-Cornago A

Nutrients Aug 2022

(DOI : 10.3390/nu14173603)

Newborn body composition and child cardiovascular risk markers: a prospective multi-ethnic Asian cohort study.

Ong YY, Tint MT, Aris IM, Yuan WL, Chen LW, Fortier MV, Choo J, Ling LH, Shek L, Tan KH, Gluckman PD, Yap F, Chong YS, Godfrey KM, Chong MF, Chan SY, Eriksson JG, Wlodek ME, De Lucia Rolfe E, Ong KK, Michael N, Lee YS

International Journal of Epidemiology Jul 2022

(DOI : 10.1093/ije/dyac154)

Association between circulating 25-hydroxyvitamin D and cardiometabolic risk factors in adults in rural and urban settings.

Mba CM, Koulman A, Forouhi NG, Sharp SJ, Imamura F, Jones K, Meadows SR, Assah F, Mbanya JC, Wareham NJ

Nutrition & diabetes Jul 2022

(DOI : 10.1038/s41387-022-00215-1)

Physical Behaviors and Their Association With Adiposity in Men and Women From a Low-Resourced African Setting.

Mendham AE, Goedecke JH, Kufe NC, Soboyisi M, Smith A, Westgate K, Brage S, Micklesfield LK

Journal of physical activity & health Jul 2022

(DOI : 10.1123/jpah.2022-0032)

Physical behaviors and their association with type 2 diabetes mellitus risk markers in urban South African middle-aged adults: an isotemporal substitutionapproach.

Kufe CN, Goedecke JH, Masemola M, Chikowore T, Soboyisi M, Smith A, Westgate K, Brage S, Micklesfield LK

BMJ open diabetes research & care Jul 2022

(DOI : 10.1136/bmjdrc-2022-002815)

Physical activity measured by accelerometry in paediatric and young adult patients with inflammatory bowel disease.

Lund K, Larsen MD, Knudsen T, Kjeldsen J, Nielsen RG, Brage S, Nørgård BM

BMC gastroenterology Jun 2022

(DOI : 10.1186/s12876-022-02358-y)

Associations between exploratory dietary patterns and incident type 2 diabetes: a federated meta-analysis of individual participant data from 25 cohort studies.

Jannasch F, Dietrich S, Bishop TRP, Pearce M, Fanidi A, O'Donoghue G, O'Gorman D, Marques-Vidal P, Vollenweider P, Bes-Rastrollo M, Byberg L, Wolk A, Hashemian M, Malekzadeh R, Poustchi H, Luft VC, de Matos SMA, Kim J, Kim MK, Kim Y, Stern D, Lajous M, Magliano DJ, Shaw JE, Akbaraly T, Kivimaki M, Maskarinec G, Le Marchand L, Martínez-González MÁ, Soedamah-Muthu SS, EPIC-InterAct Consortium EPIC-InterAct Consortium, Wareham NJ, Forouhi NG, Schulze MB

European journal of nutrition Jun 2022

(DOI : 10.1007/s00394-022-02909-9)

Dietary Patterns, Food Insecurity, and Their Relationships with Food Sources and Social Determinants in Two Small Island Developing States.

Bhagtani D, Augustus E, Haynes E, Iese V, Brown CR, Fesaitu J, Hambleton I, Badrie N, Kroll F, Saint-Ville A, Samuels TA, Forouhi NG, Benjamin-Neelon SE, Unwin N, On Behalf Of The CFaH Team

Nutrients May 2022

(DOI : 10.3390/nu14142891)

Associations between abdominal adiposity, body size and objectively measured physical activity in infants from Soweto, South Africa.

Prioreschi A, Ong KK, Rolfe EL, Westgate K, Micklesfield LK, Brage S

Maternal and Child Health Journal May 2022

(DOI : 10.1007/s10995-022-03406-5)

Effects of Limiting Recreational Screen Media Use on Physical Activity and Sleep in Families With Children: A Cluster Randomized Clinical Trial.

Pedersen J, Rasmussen MGB, Sørensen SO, Mortensen SR, Olesen LG, Brønd JC, Brage S, Kristensen PL, Grøntved A

JAMA pediatrics May 2022

(DOI : 10.1001/jamapediatrics.2022.1519)

Detecting sleep outside the clinic using wearable heart rate devices.

Perez-Pozuelo I, Posa M, Spathis D, Westgate K, Wareham N, Mascolo C, Brage S, Palotti J

Scientific reports May 2022

(DOI : 10.1038/s41598-022-11792-7)

The development, validation and application of remote blood sample collection in telehealth programmes

Koulman A, Rennie K, Parkington DA, Tyrrell CSB, Catt M, Gkrania-Klotsas E, Wareham NJ

Journal of Telemedicine and Telecare May 2022

(DOI : 10.1177/1357633X221093434)

Association of Accelerometer-Measured Sedentary Accumulation Patterns With Incident Cardiovascular Disease, Cancer, and All-Cause Mortality.

Dempsey PC, Strain T, Winkler EAH, Westgate K, Rennie KL, Wareham NJ, Brage S, Wijndaele K

Journal of the American Heart Association Apr 2022

(DOI : 10.1161/JAHA.121.023845)

Physical Activity Behaviours of a Middle-aged South African Cohort as Determined by Integrated Hip and Thigh Accelerometry.

Micklesfield LK, Westgate K, Smith A, Kufe C, Mendham AE, Lindsay T, Wijndaele K, Goedecke JH, Brage S

Medicine and Science in Sports and Exercise Apr 2022

(DOI : 10.1249/MSS.0000000000002940)

The association between self-reported physical activity and objective measures of physical activity in participants with newly diagnosed bipolar disorder, unaffected relatives, and healthy individuals.

Freyberg J, Brage S, Kessing LV, Faurholt-Jepsen M

Nordic journal of psychiatry Apr 2022

(DOI : 10.1080/08039488.2020.1831063)

The association of physical activity and cardiorespiratory fitness with β-cell dysfunction, insulin resistance, and diabetes among adults in north-western Tanzania: A cross-sectional study.

Kitilya B, Peck R, Changalucha J, Jeremiah K, Kavishe BB, Friis H, Filteau S, Krogh-Madsen R, Brage S, Faurholt-Jepsen D, Olsen MF, Praygod G

Frontiers in endocrinology Feb 2022

(DOI : 10.3389/fendo.2022.885988)

Distinct infant feeding type-specific plasma metabolites at age 3 months associate with body composition at 2 years.

van Beijsterveldt IALP, Myers PN, Snowden SG, Ong KK, Brix S, Hokken-Koelega ACS, Koulman A

Clinical nutrition (Edinburgh, Scotland) Jan 2022

(DOI : 10.1016/j.clnu.2022.04.015)

Population level physical activity before and during the first national COVID-19 lockdown: A nationally representative repeat cross-sectional study of 5 years of Active Lives data in England.

Strain T, Sharp SJ, Spiers A, Price H, Williams C, Fraser C, Brage S, Wijndaele K, Kelly P

The Lancet regional health. Europe Dec 2021

(DOI : 10.1016/j.lanepe.2021.100265)

Mobilising vitamin D from adipose tissue: The potential impact of exercise.

Hengist A, Perkin O, Gonzalez JT, Betts JA, Hewison M, Manolopoulos KN, Jones KS, Koulman A, Thompson D

Nutrition bulletin Dec 2021

(DOI : 10.1111/nbu.12369)

Face Validity of Observed Meal Patterns Reported with 7-Day Diet Diaries in a Large Population-Based Cohort Using Diurnal Variation in Concentration Biomarkers of Dietary Intake.

Lentjes MAH, Oude Griep LM, Mulligan AA, Montgomery S, Wareham NJ, Khaw KT

Nutrients Nov 2021

(DOI : 10.3390/nu14020238)

Dietary Fatty Acids, Macronutrient Substitutions, Food Sources and Incidence of Coronary Heart Disease: Findings From the EPIC-CVD Case-Cohort Study Across Nine European Countries.

Steur M, Johnson L, Sharp SJ, Imamura F, Sluijs I, Key TJ, Wood A, Chowdhury R, Guevara M, Jakobsen MU, Johansson I, Koulman A, Overvad K, Sánchez MJ, van der Schouw YT, Trichopoulou A, Weiderpass E, Wennberg M, Zheng JS, Boeing H, Boer JMA, Boutron-Ruault MC, Ericson U, Heath AK, Huybrechts I, Imaz L, Kaaks R, Krogh V, Kühn T, Kyrø C, Masala G, Melander O, Moreno-Iribas C, Panico S, Quirós JR, Rodriguez-Barranco M, Sacerdote C, Santiuste C, Skeie G, Tjønneland A, Tumino R, Verschuren WMM, Zamora-Ros R, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Riboli E, Wareham NJ, Danesh J, Butterworth AS, Forouhi NG

Journal of the American Heart Association Nov 2021

(DOI : 10.1161/JAHA.120.019814)

Associations of Serum Folate and Holotranscobalamin with Cardiometabolic Risk Factors in Rural and Urban Cameroon.

Mba CM, Koulman A, Forouhi NG, Imamura F, Assah F, Mbanya JC, Wareham NJ

Nutrients Nov 2021

(DOI : 10.3390/nu14010178)

Data Resource Profile: United Kingdom National Diet and Nutrition Survey Rolling Programme (2008-19).

Venables MC, Roberts C, Nicholson S, Bates B, Jones KS, Ashford R, Hill S, Farooq A, Koulman A, Wareham NJ, Page P

International Journal of Epidemiology Nov 2021

(DOI : 10.1093/ije/dyac106)

Hepatic steatosis is associated with anthropometry, cardio-metabolic disease risk, sex, age and urbanization, but not with ethnicity in adult Kenyans.

Kastberg SE, Lund HS, de Lucia-Rolfe E, Kaduka LU, Boit MK, Corpeleijn E, Friis H, Bernard S, Paquette M, Baas A, Rasmussen JJ, Christensen DL

Tropical medicine & international health : TM & IH Oct 2021

(DOI : 10.1111/tmi.13696)

Milk intake and incident stroke and coronary heart disease in populations of European descent: A Mendelian Randomization study.

Vissers LET, Sluijs I, Burgess S, Forouhi NG, Freisling H, Imamura F, Nilsson TK, Renstrom F, Weiderpass E, Aleksandrova K, Dahm CC, Perez-Cornago A, Schulze MB, Tong TYN, Aune D, Bonet C, Boer JMA, Boeing H, Chirlaque MD, Conchi MI, Imaz L, Jäger S, Krogh V, Kyrø C, Masala G, Melander O, Overvad K, Panico S, Sánches MJ, Sonestedt E, Tjønneland A, Tzoulaki I, Verschuren WMM, Riboli E, Wareham NJ, Danesh J, Butterworth AS, van der Schouw YT

The British journal of nutrition Oct 2021

(DOI : 10.1017/S0007114521004244)

NDNS: Diet and physical activity – a follow-up study during COVID-19

Page P, Roberts C, Collins D, Steer T, Rennie K, Westgate KL

Report Sep 2021

(DOI : 10.17863/CAM.93458 5506)

Evaluation of changes in the dietary methodology in the National Diet and Nutrition Survey Rolling Programme from Year 12 (2019 to 2020) Stage 1

Page P, Roberts C, Collins D, Steer T, Amoutzopoulos B

Report Sep 2021

(DOI : 10.17863/CAM.93614)

Identification of rare loss of function genetic variation regulating body fat distribution.

Koprulu M, Zhao Y, Wheeler E, Dong L, Rocha N, Li C, Griffin JD, Patel S, Van de Streek M, Glastonbury CA, Stewart ID, Felix RD, Luan J, Bowker N, Wittemans LBL, Kerrison ND, Cai L, Lucarelli DME, Barroso I, McCarthy MI, Scott RA, Saudek V, Kerrin SS, Wareham NJ, Semple RK, Perry JRB, O'Rahilly S, Lotta LA, Langenberg C, Savage DB

The Journal of clinical endocrinology and metabolism Sep 2021

(DOI : 10.1210/clinem/dgab877)

Trans Fatty Acid Biomarkers and Incident Type 2 Diabetes: Pooled Analysis of 12 Prospective Cohort Studies in the Fatty Acids and Outcomes Research Consortium (FORCE).

Lai HTM, Imamura F, Korat AVA, Murphy RA, Tintle N, Bassett JK, Chen J, Kröger J, Chien KL, Senn M, Wood AC, Forouhi NG, Schulze MB, Harris WS, Vasan RS, Hu F, Giles GG, Hodge A, Djoussé L, Brouwer IA, Qian F, Sun Q, Wu JHY, Marklund M, Lemaitre RN, Siscovick DS, Fretts AM, Shadyab AH, Manson JE, Howard BV, Robinson JG, Wallace RB, Wareham NJ, Chen YI, Rotter JI, Tsai MY, Micha R, Mozaffarian D, Fatty Acids and Outcomes Research Consortium (FORCE)

Diabetes care Aug 2021

(DOI : 10.2337/dc21-1756)

Metabolomics in early life and the association with body composition at age 2 years.

van Beijsterveldt IALP, Snowden SG, Myers PN, de Fluiter KS, van de Heijning B, Brix S, Ong KK, Dunger DB, Hokken-Koelega ACS, Koulman A

Pediatric Obesity Aug 2021

(DOI : 10.1111/ijpo.12859)

Thiamine deficiency in Gambian women of reproductive age.

Bourassa MW, Gomes F, Jones KS, Koulman A, Prentice AM, Cerami C

Annals of the New York Academy of Sciences Aug 2021

(DOI : 10.1111/nyas.14695)

Delayed Processing of Chilled Whole Blood for 24 Hours Does Not Affect the Concentration of the Majority of Micronutrient Status Biomarkers.

Jones KS, Meadows SR, Chamberlain K, Parkington DA, Collins D, Page P, Koulman A

The Journal of nutrition Jul 2021

(DOI : 10.1093/jn/nxab267)

Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations.

Haslam DE, Peloso GM, Guirette M, Imamura F, Bartz TM, Pitsillides AN, Wang CA, Li-Gao R, Westra JM, Pitkänen N, Young KL, Graff M, Wood AC, Braun KVE, Luan J, Kähönen M, Kiefte-de Jong JC, Ghanbari M, Tintle N, Lemaitre RN, Mook-Kanamori DO, North K, Helminen M, Mossavar-Rahmani Y, Snetselaar L, Martin LW, Viikari JS, Oddy WH, Pennell CE, Rosendall FR, Ikram MA, Uitterlinden AG, Psaty BM, Mozaffarian D, Rotter JI, Taylor KD, Lehtimäki T, Raitakari OT, Livingston KA, Voortman T, Forouhi NG, Wareham NJ, de Mutsert R, Rich SS, Manson JE, Mora S, Ridker PM, Merino J, Meigs JB, Dashti HS, Chasman DI, Lichtenstein AH, Smith CE, Dupuis J, Herman MA, McKeown NM

Circulation. Genomic and precision medicine Jul 2021

(DOI : 10.1161/CIRCGEN.120.003288)

Levels and correlates of physical activity and capacity among HIV-infected compared to HIV-uninfected individuals.

Kitilya B, Praygod G, Peck R, Changalucha J, Jeremiah K, Kavishe BB, Friis H, Filteau S, Faurholt-Jepsen D, Krogh-Madsen R, Brage S, Olsen MF

PLoS ONE Jun 2021

(DOI : 10.1371/journal.pone.0262298)

Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit.

Ashley B, Simner C, Manousopoulou A, Jenkinson C, Hey F, Frost JM, Rezwan FI, White CH, Lofthouse EM, Hyde E, Cooke LDF, Barton S, Mahon P, Curtis EM, Moon RJ, Crozier SR, Inskip HM, Godfrey KM, Holloway JW, Cooper C, Jones KS, Lewis RM, Hewison M, Garbis SDD, Branco MR, Harvey NC, Cleal JK

eLife Jun 2021

(DOI : 10.7554/eLife.71094)

Objectively Measured Physical Activity and Body Fatness: Associations with Total Body Fat, Visceral Fat, and Liver Fat.

Winters-van Eekelen E, van der Velde JHPM, Boone SC, Westgate K, Brage S, Lamb HJ, Rosendaal FR, de Mutsert R

Medicine and Science in Sports and Exercise Jun 2021

(DOI : 10.1249/MSS.0000000000002712)

Physical activity intensity profiles associated with cardiometabolic risk in middle-aged to older men and women.

Dempsey PC, Aadland E, Strain T, Kvalheim OM, Westgate K, Lindsay T, Khaw KT, Wareham NJ, Brage S, Wijndaele K

Preventive medicine May 2021

(DOI : 10.1016/j.ypmed.2022.106977)

Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses.

Emerging Risk Factors Collaboration/EPIC-CVD/Vitamin D Studies Collaboration

The lancet. Diabetes & endocrinology May 2021

(DOI : 10.1016/S2213-8587(21)00263-1)

Description of the updated nutrition calculation of the Oxford WebQ questionnaire and comparison with the previous version among 207,144 participants in UK Biobank.

Perez-Cornago A, Pollard Z, Young H, van Uden M, Andrews C, Piernas C, Key TJ, Mulligan A, Lentjes M

European journal of nutrition May 2021

(DOI : 10.1007/s00394-021-02558-4)

Study at Cambridge

About the University

Research at Cambridge