MRC Epidemiology Unit

 

Early development of infant gut microbiota in relation to breastfeeding and human milk oligosaccharides.

Chichlowski M, van Diepen JA, Prodan A, Olga L, Ong KK, Kortman GAM, Dunger DB, Gross G

Frontiers in nutrition. Mar 2023

(DOI : 10.3389/fnut.2023.1003032)

---

Butyrate in Human Milk: Associations with Milk Microbiota, Milk Intake Volume, and Infant Growth.

Olga L, van Diepen JA, Chichlowski M, Petry CJ, Vervoort J, Dunger DB, Kortman GAM, Gross G, Ong KK

Nutrients. Feb 2023

(DOI : 10.3390/nu15040916)

---

Associations between breast milk intake volume, macronutrient intake, and infant growth in a longitudinal birth cohort: the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF).

Olga L, Vervoort J, van Diepen JA, Gross G, Petry CJ, Prentice PM, Chichlowski M, van Tol EA, Hughes IA, Dunger DB, Ong KK

The British journal of nutrition. Oct 2022

(DOI : 10.1017/S0007114522003178)

---

Early weight gain influences duration of breast feeding: prospective cohort study.

Olga L, van Diepen JA, Gross G, Dunger DB, Ong KK

Archives of Disease in Childhood. Jul 2022

(DOI : 10.1136/archdischild-2022-323999)

---

Metabolomics in early life and the association with body composition at age 2 years.

van Beijsterveldt IALP, Snowden SG, Myers PN, de Fluiter KS, van de Heijning B, Brix S, Ong KK, Dunger DB, Hokken-Koelega ACS, Koulman A

Pediatric Obesity. Aug 2021

(DOI : 10.1111/ijpo.12859)

---

Extensive Study of Breast Milk and Infant Growth: Protocol of the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF).

Olga L, Petry CJ, van Diepen JA, Prentice PM, Hughes IA, Vervoort J, Boekhorst J, Chichlowski M, Gross G, Dunger DB, Ong KK

Nutrients. Jul 2021

(DOI : 10.3390/nu13082879)

---

Associations between Maternal Iron Supplementation in Pregnancy and Changes in Offspring Size at Birth Reflect Those of Multiple Micronutrient Supplementation.

Petry CJ, Ong KK, Hughes IA, Dunger DB

Nutrients. May 2021

(DOI : 10.3390/nu13072480)

---

Anthropometry-based prediction of body composition in early infancy compared to air-displacement plethysmography.

Olga L, van Beijsterveldt IALP, Hughes IA, Dunger DB, Ong KK, Hokken-Koelega ACS, De Lucia Rolfe E

Pediatric Obesity. Apr 2021

(DOI : 10.1111/ijpo.12818)

---

A one-year study of human milk oligosaccharide profiles in the milk of healthy UK mothers and their relationship to maternal FUT2 genotype.

Durham SD, Robinson RC, Olga L, Ong KK, Chichlowski M, Dunger DB, Barile D

Glycobiology. Mar 2021

(DOI : 10.1093/glycob/cwab057)

---

The High-Risk Type 1 Diabetes HLA-DR and HLA-DQ Polymorphisms Are Differentially Associated With Growth and IGF-I Levels in Infancy: The Cambridge Baby Growth Study.

Eleftheriou A, Petry CJ, Hughes IA, Ong KK, Dunger DB

Diabetes care. Nov 2020

(DOI : 10.2337/dc20-2820)

---

Folic acid supplementation during pregnancy and associations with offspring size at birth and adiposity: a cohort study.

Petry CJ, Ong KK, Hughes IA, Dunger DB

BMC research notes. Nov 2020

(DOI : 10.1186/s13104-021-05575-y)

---

A Novel method for the identification and quantification of weight faltering.

Naumenko DJ, Dykes J, O'Connor GK, Stanley Z, Affara N, Doel AM, Drammeh S, Dunger DB, Faal A, Ong KK, Sosseh F, Prentice AM, Moore SE, Bernstein RM

American journal of physical anthropology. Nov 2020

(DOI : 10.1002/ajpa.24217)

---

Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA.

Quilter CR, Harvey KM, Bauer J, Skinner BM, Gomez M, Shrivastava M, Doel AM, Drammeh S, Dunger DB, Moore SE, Ong KK, Prentice AM, Bernstein RM, Sargent CA, Affara NA

FASEB bioAdvances. Oct 2020

(DOI : 10.1096/fba.2020-00101)

---

Multiple Micronutrient Supplementation during Pregnancy and Increased Birth Weight and Skinfold Thicknesses in the Offspring: The Cambridge Baby Growth Study.

Petry CJ, Ong KK, Hughes IA, Dunger DB

Nutrients. Sep 2020

(DOI : 10.3390/nu12113466)

---

Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity.

Olga L, van Diepen JA, Bobeldijk-Pastorova I, Gross G, Prentice PM, Snowden SG, Furse S, Kooistra T, Hughes IA, Schoemaker MH, van Tol EAF, van Duyvenvoorde W, Wielinga PY, Ong KK, Dunger DB, Kleemann R, Koulman A

EBioMedicine. Sep 2020

(DOI : 10.1016/j.ebiom.2020.103198)

---

Pregnancy Serum DLK1 Concentrations Are Associated With Indices of Insulin Resistance and Secretion.

Petry CJ, Burling KA, Barker P, Hughes IA, Ong KK, Dunger DB

The Journal of clinical endocrinology and metabolism. Jul 2020

(DOI : 10.1210/clinem/dgab123)

---

Which infancy growth parameters are associated with later adiposity? The Cambridge Baby Growth Study.

Ong KK, Cheng TS, Olga L, Prentice PM, Petry CJ, Hughes IA, Dunger DB

Annals of human biology. May 2020

(DOI : 10.1080/03014460.2020.1745887)

---

Identification of nutritionally modifiable hormonal and epigenetic drivers of positive and negative growth deviance in rural African fetuses and infants: Project protocol and cohort description.

Moore SE, Doel AM, Ong KK, Dunger DB, Affara NA, Prentice AM, Bernstein RM, HERO-G Working Group HERO-G Working Group

Gates open research. Feb 2020

(DOI : 10.12688/gatesopenres.13101.1)

---

Timing of the Infancy-Childhood Growth Transition in Rural Gambia.

Bernstein RM, O'Connor GK, Vance EA, Affara N, Drammeh S, Dunger DB, Faal A, Ong KK, Sosseh F, Prentice AM, Moore SE

Frontiers in endocrinology. Dec 2019

(DOI : 10.3389/fendo.2020.00142)

---

Temporal Trends in Maternal Food Intake Frequencies and Associations with Gestational Diabetes: The Cambridge Baby Growth Study.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Nutrients. Sep 2019

(DOI : 10.3390/nu11112822)

---

Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism.

Furse S, Snowden SG, Olga L, Prentice P, Ong KK, Hughes IA, Acerini CL, Dunger DB, Koulman A

Scientific reports. Jun 2019

(DOI : 10.1038/s41598-019-50693-0)

---

Maternal serum concentrations of bisphenol A and propyl paraben in early pregnancy are associated with male infant genital development.

Fisher BG, Thankamony A, Mendiola J, Petry CJ, Frederiksen H, Andersson AM, Juul A, Ong KK, Dunger DB, Hughes IA, Acerini CL

Human reproduction (Oxford, England). Apr 2019

(DOI : 10.1093/humrep/deaa045)

---

Temporal trends without seasonal effects on gestational diabetes incidence relate to reductions in indices of insulin secretion: the Cambridge Baby Growth Study.

Petry CJ, Fisher BG, Ong KK, Hughes IA, Acerini CL, Dunger DB

Acta diabetologica. Apr 2019

(DOI : 10.1007/s00592-019-01354-1)

---

Age at Menarche and Blood Pressure in Pregnancy.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Pregnancy hypertension. Feb 2019

(DOI : 10.1016/j.preghy.2019.01.004)

---

Reduced size at birth and persisting reductions in adiposity in recent, compared with earlier, cohorts of infants born to mothers with gestational diabetes mellitus.

Prentice PM, Olga L, Petry CJ, Simmons D, Murphy HR, Hughes IA, Acerini CL, Ong KK, Dunger DB

Diabetologia. Jan 2019

(DOI : 10.1007/s00125-019-4970-6)

---

The influence of maternal pregnancy glucose concentrations on associations between a fetal imprinted gene allele score and offspring size at birth.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

BMC research notes. Oct 2018

(DOI : 10.1186/s13104-018-3933-1)

---

Human Milk Short-Chain Fatty Acid Composition is Associated with Adiposity Outcomes in Infants.

Schoemaker MH, Acerini CL, Hughes IA, Koulman A, Ong KK, Dunger DB

The Journal of nutrition. Sep 2018

(DOI : 10.1093/jn/nxy320)

---

Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study.

Petry CJ, Ong KK, Burling KA, Barker P, Goodburn SF, Perry JRB, Acerini CL, Hughes IA, Painter RC, Afink GB, Dunger DB, O'Rahilly S

Wellcome open research. Sep 2018

(DOI : 10.12688/wellcomeopenres.14818.1)

---

Age at menarche and the future risk of gestational diabetes: a systematic review and dose response meta-analysis.

Petry CJ, Ong KK, Dunger DB

Acta diabetologica. Jun 2018

(DOI : 10.1007/s00592-018-1214-z)

---

Associations between the maternal circulating lipid profile in pregnancy and fetal imprinted gene alleles: a cohort study.

Petry CJ, Koulman A, Lu L, Jenkins B, Furse S, Prentice P, Matthews L, Hughes IA, Acerini CL, Ong KK, Dunger DB

Reproductive biology and endocrinology : RB&E. Jun 2018

(DOI : 10.1186/s12958-018-0399-x)

---

The association between age at menarche and later risk of gestational diabetes is mediated by insulin resistance.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Acta diabetologica. Mar 2018

(DOI : 10.1007/s00592-018-1162-7)

---

Serum Phthalate and Triclosan Levels Have Opposing Associations With Risk Factors for Gestational Diabetes Mellitus.

Fisher BG, Frederiksen H, Andersson AM, Juul A, Thankamony A, Ong KK, Dunger DB, Hughes IA, Acerini CL

Frontiers in endocrinology. Dec 2017

(DOI : 10.3389/fendo.2018.00099)

---

Vomiting in pregnancy is associated with a higher risk of low birth weight: a cohort study.

Petry CJ, Ong KK, Beardsall K, Hughes IA, Acerini CL, Dunger DB

BMC pregnancy and childbirth. Aug 2017

(DOI : 10.1186/s12884-018-1786-1)

---

Associations between bacterial infections and blood pressure in pregnancy.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Pregnancy hypertension. May 2017

(DOI : 10.1016/j.preghy.2017.09.004)

---

Early Pregnancy-Associated Plasma Protein A Concentrations Are Associated With Third Trimester Insulin Sensitivity.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Frystyk J, Dunger DB

The Journal of clinical endocrinology and metabolism. Jan 2017

(DOI : 10.1210/jc.2017-00272)

---

Associations between a fetal imprinted gene allele score and late pregnancy maternal glucose concentrations.

Petry CJ, Prentice P, Hayes MG, Nodzenski M, Scholtens DM, Hughes IA, Acerini CL, Ong KK, Lowe WL, Dunger DB

Diabetes & metabolism. Nov 2016

(DOI : 10.1016/j.diabet.2017.03.002)

---

Clustering of cardio-metabolic risk factors in parents of adolescents with type 1 diabetes and microalbuminuria.

Marcovecchio ML, Tossavainen PH, Owen K, Fullah C, Benitez-Aguirre P, Masi S, Ong K, Nguyen H, Chiesa ST, Dalton RN, Deanfield J, Dunger DB

Pediatric diabetes. Sep 2016

(DOI : 10.1111/pedi.12515)

---

Associations Between Fetal Imprinted Genes and Maternal Blood Pressure in Pregnancy.

Petry CJ, Sanz Marcos N, Pimentel G, Hayes MG, Nodzenski M, Scholtens DM, Hughes IA, Acerini CL, Ong KK, Lowe WL, Dunger DB

Hypertension (Dallas, Tex. : 1979). Aug 2016

(DOI : 10.1161/HYPERTENSIONAHA.116.08261)

---

An Unbiased Lipidomics Approach Identifies Early Second Trimester Lipids Predictive of Maternal Glycemic Traits and Gestational Diabetes Mellitus.

Lu L, Koulman A, Petry CJ, Jenkins B, Matthews L, Hughes IA, Acerini CL, Ong KK, Dunger DB

Diabetes care. Apr 2016

(DOI : 10.2337/dc16-0863)

---

Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants.

Fisher BG, Thankamony A, Hughes IA, Ong KK, Dunger DB, Acerini CL

Human reproduction (Oxford, England). Apr 2016

(DOI : 10.1093/humrep/dew196)

---

Adiposity in Children Born Small for Gestational Age Is Associated With β-Cell Function, Genetic Variants for Insulin Resistance, and Response to Growth Hormone Treatment.

Thankamony A, Jensen RB, O'Connell SM, Day F, Kirk J, Donaldson M, Ivarsson SA, Söder O, Roche E, Hoey H, Ong KK, Dunger DB, Juul A

The Journal of clinical endocrinology and metabolism. Nov 2015

(DOI : 10.1210/jc.2015-3019)

---

Breast milk nutrient content and infancy growth.

Prentice P, Ong KK, Schoemaker MH, Vervoort J, Hughes IA, Acerini CL, Dunger DB

Acta paediatrica (Oslo, Norway : 1992). Aug 2015

(DOI : 10.1111/apa.13362)

---

Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults.

De Lucia Rolfe E, Ong KK, Sleigh A, Dunger DB, Norris SA

BMC Public Health. Jun 2015

(DOI : 10.1186/s12889-015-2147-x)

---

Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.

Day FR, Hinds DA, Tung JY, Stolk L, Styrkarsdottir U, Saxena R, Bjonnes A, Broer L, Dunger DB, Halldorsson BV, Lawlor DA, Laval G, Mathieson I, McCardle WL, Louwers Y, Meun C, Ring S, Scott RA, Sulem P, Uitterlinden AG, Wareham NJ, Thorsteinsdottir U, Welt C, Stefansson K, Laven JSE, Ong KK, Perry JRB

Nature communications. Feb 2015

(DOI : 10.1038/ncomms9464)

---

Age at Weaning and Infant Growth: Primary Analysis and Systematic Review.

Vail B, Prentice P, Dunger DB, Hughes IA, Acerini CL, Ong KK

The Journal of pediatrics. Jan 2015

(DOI : 10.1016/j.jpeds.2015.05.003)

---

Genetic markers of insulin sensitivity and insulin secretion are associated with spontaneous postnatal growth and response to growth hormone treatment in short SGA children: the North European SGA Study (NESGAS).

Jensen RB, Thankamony A, Day F, Scott RA, Langenberg C, Kirk J, Donaldson M, Ivarsson SA, Söder O, Roche E, Hoey H, Juul A, Ong KK, Dunger DB

The Journal of clinical endocrinology and metabolism. Dec 2014

(DOI : 10.1210/jc.2014-3469)

---

Associations between genetic obesity susceptibility and early postnatal fat and lean mass: an individual participant meta-analysis.

Elks CE, Heude B, de Zegher F, Barton SJ, Clément K, Inskip HM, Koudou Y, Cooper C, Dunger DB, Ibáñez L, Charles MA, Ong KK

JAMA pediatrics. Oct 2014

(DOI : 10.1001/jamapediatrics.2014.1619)

---

Impact on offspring methylation patterns of maternal gestational diabetes mellitus and intrauterine growth restraint suggest common genes and pathways linked to subsequent type 2 diabetes risk.

Quilter CR, Cooper WN, Cliffe KM, Skinner BM, Prentice PM, Nelson L, Bauer J, Ong KK, Constância M, Lowe WL, Affara NA, Dunger DB

FASEB journal : official publication of the Federation of American Societies for Experimental Biology. Aug 2014

(DOI : 10.1096/fj.14-255240)

---

Postnatal penile growth concurrent with mini-puberty predicts later sex-typed play behavior: Evidence for neurobehavioral effects of the postnatal androgen surge in typically developing boys.

Pasterski V, Acerini CL, Dunger DB, Ong KK, Hughes IA, Thankamony A, Hines M

Hormones and behavior. Aug 2014

(DOI : 10.1016/j.yhbeh.2015.01.002)

---

Even transient rapid infancy weight gain is associated with higher BMI in young adults and earlier menarche.

Salgin B, Norris SA, Prentice P, Pettifor JM, Richter LM, Ong KK, Dunger DB

International Journal of Obesity. Jun 2014

(DOI : 10.1038/ijo.2015.25)

---

Lipidomic analyses, breast- and formula-feeding, and growth in infants.

Prentice P, Koulman A, Matthews L, Acerini CL, Ong KK, Dunger DB

The Journal of pediatrics. Jun 2014

(DOI : 10.1016/j.jpeds.2014.10.021)

---

Hyperinsulinaemic androgen excess in adolescent girls.

Ibáñez L, Ong KK, López-Bermejo A, Dunger DB, de Zegher F

Nature reviews. Endocrinology. Apr 2014

(DOI : 10.1038/nrendo.2014.58)

---

Pros and cons of GnRHa treatment for early puberty in girls.

Willemsen RH, Elleri D, Williams RM, Ong KK, Dunger DB

Nature reviews. Endocrinology. Apr 2014

(DOI : 10.1038/nrendo.2014.40)

---

Serum uric acid and cardiovascular risk among Portuguese adolescents.

Gonçalves JP, Ramos E, Severo M, Wong MC, Ong KK, Dunger DB, Lopes C

The Journal of adolescent health : official publication of the Society for Adolescent Medicine. Mar 2014

(DOI : 10.1016/j.jadohealth.2014.11.010)

---

Anogenital distance and penile length in infants with hypospadias or cryptorchidism: comparison with normative data.

Thankamony A, Lek N, Carroll D, Williams M, Dunger DB, Acerini CL, Ong KK, Hughes IA

Environmental health perspectives. Jun 2013

(DOI : 10.1289/ehp.1307178)

---

Ultrasound estimates of visceral and subcutaneous-abdominal adipose tissues in infancy.

De Lucia Rolfe E, Modi N, Uthaya S, Hughes IA, Dunger DB, Acerini C, Stolk RP, Ong KK

Journal of Obesity. Dec 2012

(DOI : 10.1155/2013/951954)

---

Peripubertal changes in circulating antimüllerian hormone levels in girls.

Lashen H, Dunger DB, Ness A, Ong KK

Fertility and sterility. Oct 2012

(DOI : 10.1016/j.fertnstert.2013.01.139)

---

Higher fasting plasma free fatty acid levels are associated with lower insulin secretion in children and adults and a higher incidence of type 2 diabetes.

Salgin B, Ong KK, Thankamony A, Emmett P, Wareham NJ, Dunger DB

The Journal of clinical endocrinology and metabolism. Jun 2012

(DOI : 10.1210/jc.2012-1428)

---

Higher levels of IGF-I and adrenal androgens at age 8 years are associated with earlier age at menarche in girls.

Thankamony A, Ong KK, Ahmed ML, Ness AR, Holly JM, Dunger DB

The Journal of clinical endocrinology and metabolism. Mar 2012

(DOI : 10.1210/jc.2011-3261)

---

DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial.

Cooper WN, Khulan B, Owens S, Elks CE, Seidel V, Prentice AM, Belteki G, Ong KK, Affara NA, Constância M, Dunger DB

FASEB journal : official publication of the Federation of American Societies for Experimental Biology. Jan 2012

(DOI : 10.1096/fj.11-192708)

---

Associations between paternally transmitted fetal IGF2 variants and maternal circulating glucose concentrations in pregnancy.

Petry CJ, Seear RV, Wingate DL, Manico L, Acerini CL, Ong KK, Hughes IA, Dunger DB

Diabetes. Sep 2011

(DOI : 10.2337/db11-0689)

---

Polycystic ovarian syndrome during puberty and adolescence.

Williams RM, Ong KK, Dunger DB

Molecular and cellular endocrinology. Aug 2011

(DOI : 10.1016/j.mce.2013.01.005)

---

Validation of ultrasound estimates of visceral fat in black South African adolescents.

De Lucia Rolfe E, Norris SA, Sleigh A, Brage S, Dunger DB, Stolk RP, Ong KK

Obesity (Silver Spring, Md.). Jul 2011

(DOI : 10.1038/oby.2011.213)

---

Maternally transmitted foetal H19 variants and associations with birth weight.

Petry CJ, Seear RV, Wingate DL, Acerini CL, Ong KK, Hughes IA, Dunger DB

Human genetics. Mar 2011

(DOI : 10.1007/s00439-011-1005-x)

---

Breastfeeding and infant temperament at age three months.

Lauzon-Guillain Bd, Wijndaele K, Clark M, Acerini CL, Hughes IA, Dunger DB, Wells JC, Ong KK

PLoS ONE. Feb 2011

(DOI : 10.1371/journal.pone.0029326)

---

Increased placental glucose transport rates in pregnant mice carrying fetuses with targeted disruption of their placental-specific Igf2 transcripts are not associated with raised circulating glucose concentrations.

Petry CJ, Evans ML, Wingate DL, Ong KK, Reik W, Constância M, Dunger DB

Experimental diabetes research. Sep 2010

(DOI : 10.1155/2011/171376)

---

Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.

Elks CE, Loos RJ, Sharp SJ, Langenberg C, Ring SM, Timpson NJ, Ness AR, Davey Smith G, Dunger DB, Wareham NJ, Ong KK

PLoS Medicine. Oct 2009

(DOI : 10.1371/journal.pmed.1000284)

---

Raised late pregnancy glucose concentrations in mice carrying pups with targeted disruption of H19delta13.

Petry CJ, Evans ML, Wingate DL, Ong KK, Reik W, Constância M, Dunger DB

Diabetes. Oct 2009

(DOI : 10.2337/db09-0757)

---

Heritability of childhood weight gain from birth and risk markers for adult metabolic disease in prepubertal twins.

Beardsall K, Ong KK, Murphy N, Ahmed ML, Zhao JH, Peeters MW, Dunger DB

The Journal of clinical endocrinology and metabolism. Sep 2009

(DOI : 10.1210/jc.2009-0757)

---

Prevalence and determinants of hyperglycemia in very low birth weight infants: cohort analyses of the NIRTURE study.

Beardsall K, Vanhaesebrouck S, Ogilvy-Stuart AL, Vanhole C, Palmer CR, Ong K, vanWeissenbruch M, Midgley P, Thompson M, Thio M, Cornette L, Ossuetta I, Iglesias I, Theyskens C, de Jong M, Gill B, Ahluwalia JS, de Zegher F, Dunger DB

The Journal of pediatrics. Aug 2009

(DOI : 10.1016/j.jpeds.2010.04.032)

---

The descriptive epidemiology of congenital and acquired cryptorchidism in a UK infant cohort.

Acerini CL, Miles HL, Dunger DB, Ong KK, Hughes IA

Archives of Disease in Childhood. Jun 2009

(DOI : 10.1136/adc.2008.150219)

---

Insulin-like growth factor I concentrations in infancy predict differential gains in body length and adiposity: the Cambridge Baby Growth Study.

Ong KK, Langkamp M, Ranke MB, Whitehead K, Hughes IA, Acerini CL, Dunger DB

The American Journal of Clinical Nutrition. May 2009

(DOI : 10.3945/ajcn.2008.27408)

---

Anogenital distance from birth to 2 years: a population study.

Thankamony A, Ong KK, Dunger DB, Acerini CL, Hughes IA

Environmental health perspectives. Apr 2009

(DOI : 10.1289/ehp.0900881)

---

Association between a common variant near MC4R and change in body mass index develops by two weeks of age.

Petry CJ, López-Bermejo A, Díaz M, Sebastiani G, Ong KK, de Zegher F, Dunger DB, Ibáñez L

Hormone research in paediatrics. Mar 2009

(DOI : 10.1159/000284392)

---

Infancy weight gain predicts childhood body fat and age at menarche in girls.

Ong KK, Emmett P, Northstone K, Golding J, Rogers I, Ness AR, Wells JC, Dunger DB

The Journal of clinical endocrinology and metabolism. Feb 2009

(DOI : 10.1210/jc.2008-2489)

---

Common polymorphic variation in the genetically diverse African insulin gene and its association with size at birth.

Petry CJ, Rayco-Solon P, Fulford AJ, Stead JD, Wingate DL, Ong KK, Sirugo G, Prentice AM, Dunger DB

Human genetics. Jan 2009

(DOI : 10.1007/s00439-009-0681-2)

---

Childhood obesity and the timing of puberty.

Ahmed ML, Ong KK, Dunger DB

Trends in endocrinology and metabolism: TEM. Sep 2008

(DOI : 10.1016/j.tem.2009.02.004)

---

Pregnancy insulin, glucose, and BMI contribute to birth outcomes in nondiabetic mothers.

Ong KK, Diderholm B, Salzano G, Wingate D, Hughes IA, MacDougall J, Acerini CL, Dunger DB

Diabetes care. Aug 2008

(DOI : 10.2337/dc08-1111)

---

Ghrelin receptor gene polymorphisms and body size in children and adults.

Garcia EA, Heude B, Petry CJ, Gueorguiev M, Hassan-Smith ZK, Spanou A, Ring SM, Dunger DB, Wareham NJ, Sandhu MS, Ong KK, Korbonits M

The Journal of clinical endocrinology and metabolism. Jul 2008

(DOI : 10.1210/jc.2008-0366)

---

Genetics of size at birth.

Dunger DB, Petry CJ, Ong KK

Diabetes care. Feb 2008

(DOI : 30/Supplement_2/S150)

---

The development of microalbuminuria is associated with raised longitudinal adiponectin levels in female but not male adolescent patients with type 1 diabetes.

Amin R, Frystyk J, Ong K, Dalton RN, Flyvbjerg A, Dunger DB

Diabetologia. Feb 2008

(DOI : 10.1007/s00125-008-1081-1)

---

Association analysis of the IGF1 gene with childhood growth, IGF-1 concentrations and type 1 diabetes.

Vella A, Bouatia-Naji N, Heude B, Cooper JD, Lowe CE, Petry C, Ring SM, Dunger DB, Todd JA, Ong KK

Diabetologia. Dec 2007

(DOI : 10.1007/s00125-008-0970-7)

---

A randomized cross-over trial to identify the optimal use of insulin glargine in prepubertal children using a three-times daily insulin regimen.

Fröhlich-Reiterer EE, Ong KK, Regan F, Salzano G, Acerini CL, Dunger DB

Diabetic medicine : a journal of the British Diabetic Association. Nov 2007

(DOI : 10.1111/j.1464-5491.2007.02277.x)

---

Flutamide metformin for post-menarcheal girls with preclinical ovarian androgen excess: evidence for differential response by androgen receptor genotype.

Ong KK, de Zegher F, López-Bermejo A, Dunger DB, Ibáñez L

European journal of endocrinology. Nov 2007

(DOI : 10.1530/EJE-07-0261)

---

Relationships of urinary adrenal steroids at age 8 years with birth weight, postnatal growth, blood pressure, and glucose metabolism.

Honour JW, Jones R, Leary S, Golding J, Ong KK, Dunger DB

The Journal of clinical endocrinology and metabolism. Aug 2007

(DOI : 10.1210/jc.2007-0851)

---

Session 7: Early nutrition and later health early developmental pathways of obesity and diabetes risk.

Dunger DB, Salgin B, Ong KK

The Proceedings of the Nutrition Society. Jul 2007

(DOI : 10.1017/S0029665107005721)

---

Persisting benefits 12-18 months after discontinuation of pubertal metformin therapy in low birthweight girls.

Ong K, de Zegher F, Valls C, Dunger DB, Ibáñez L

Clinical endocrinology. Jul 2007

(DOI : 10.1111/j.1365-2265.2007.02952.x)

---

Does the fetal genotype affect maternal physiology during pregnancy?

Petry CJ, Ong KK, Dunger DB

Trends in molecular medicine. Mar 2007

(DOI : 10.1016/j.molmed.2007.07.007)

---

Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies.

Semple RK, Halberg NH, Burling K, Soos MA, Schraw T, Luan J, Cochran EK, Dunger DB, Wareham NJ, Scherer PE, Gorden P, O'Rahilly S

Diabetes. Feb 2007

(DOI : 10.2337/db06-1665)

---

Early elective insulin therapy can reduce hyperglycemia and increase insulin-like growth factor-I levels in very low birth weight infants.

Beardsall K, Ogilvy-Stuart AL, Frystyk J, Chen JW, Thompson M, Ahluwalia J, Ong KK, Dunger DB

The Journal of pediatrics. Jan 2007

(DOI : 10.1016/j.jpeds.2007.04.068)

---

Lack of association between common polymorphisms in the 17beta-hydroxysteroid dehydrogenase type V gene (HSD17B5) and precocious pubarche.

Petry CJ, Ong KK, Wingate DL, de Zegher F, Ibáñez L, Dunger DB

The Journal of steroid biochemistry and molecular biology. Dec 2006

(DOI : 10.1016/j.jsbmb.2007.01.004)

---

Association of weight gain in infancy and early childhood with metabolic risk in young adults.

Ekelund U, Ong KK, Linné Y, Neovius M, Brage S, Dunger DB, Wareham NJ, Rössner S

The Journal of clinical endocrinology and metabolism. Oct 2006

(DOI : 10.1210/jc.2006-1071)

---

Earlier mother's age at menarche predicts rapid infancy growth and childhood obesity.

Ong KK, Northstone K, Wells JC, Rubin C, Ness AR, Golding J, Dunger DB

PLoS Medicine. Oct 2006

(DOI : 10.1371/journal.pmed.0040132)

---

Lessons from large population studies on timing and tempo of puberty (secular trends and relation to body size): the European trend.

Ong KK, Ahmed ML, Dunger DB

Molecular and cellular endocrinology. Jun 2006

(DOI : 10.1016/j.mce.2006.04.018)

---

Metformin treatment to prevent early puberty in girls with precocious pubarche.

Ibáñez L, Ong K, Valls C, Marcos MV, Dunger DB, de Zegher F

The Journal of clinical endocrinology and metabolism. May 2006

(DOI : 10.1210/jc.2006-0336)

---

Effects of growth hormone treatment on neutrophil count in children born small for gestational age.

Ibáñez L, Ong K, Dunger DB, Zegher Fd

Pediatrics. May 2006

(DOI : 10.1542/peds.2006-0022)

---

Sex-discordant associations with adiponectin levels and lipid profiles in children.

Ong KK, Frystyk J, Flyvbjerg A, Petry CJ, Ness A, Dunger DB

Diabetes. Apr 2006

(DOI : 10.2337/db05-1272)

---

Growth hormone binding protein levels in children are associated with birth weight, postnatal weight gain, and insulin secretion.

Ong KK, Elmlinger M, Jones R, Emmett P, Holly J, Ranke MB, Dunger DB

Metabolism: clinical and experimental. Apr 2006

(DOI : 10.1016/j.metabol.2007.06.004)

---

The insulin gene variable number of tandem repeat: associations and interactions with childhood body fat mass and insulin secretion in normal children.

Heude B, Petry CJ, Pembrey M, Dunger DB, Ong KK

The Journal of clinical endocrinology and metabolism. Apr 2006

(DOI : 10.1210/jc.2005-2055)

---

Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children.

Ibáñez L, Ong K, Dunger DB, de Zegher F

The Journal of clinical endocrinology and metabolism. Mar 2006

(DOI : 10.1210/jc.2005-2778)

---

Dietary energy intake at the age of 4 months predicts postnatal weight gain and childhood body mass index.

Ong KK, Emmett PM, Noble S, Ness A, Dunger DB

Pediatrics. Mar 2006

(DOI : 10.1542/peds.2005-1668)

---

Metformin therapy during puberty delays menarche, prolongs pubertal growth, and augments adult height: a randomized study in low-birth-weight girls with early-normal onset of puberty.

Ibáñez L, Valls C, Ong K, Dunger DB, de Zegher F

The Journal of clinical endocrinology and metabolism. Feb 2006

(DOI : 10.1210/jc.2005-2329)

---

Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES).

Ekelund U, Ong K, Linné Y, Neovius M, Brage S, Dunger DB, Wareham NJ, Rössner S

The American Journal of Clinical Nutrition. Feb 2006

(DOI : 10.1093/ajcn/83.2.324)

---

Associations between common variation in the aromatase gene promoter region and testosterone concentrations in two young female populations.

Petry CJ, Ong KK, Michelmore KF, Artigas S, Wingate DL, Balen AH, de Zegher F, Ibáñez L, Dunger DB

The Journal of steroid biochemistry and molecular biology. Jul 2005

(DOI : 10.1016/j.jsbmb.2005.09.007)

---