MRC Epidemiology Unit - Publications Database

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There are 386 publications that match the search string

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programme => Early Life Aetiology and Mechanisms of Diabetes and Related Metabolic Disorders

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Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour.

Mills MC, Tropf FC, Brazel DM, van Zuydam N, Vaez A, eQTLGen Consortium, BIOS Consortium, Human Reproductive Behaviour Consortium, Pers TH, Snieder H, Perry JRB, Ong KK, den Hoed M, Barban N, Day FR

Nature Human Behaviour Jun 2020

(DOI : 10.1038/s41562-021-01135-3)

Plasma Vitamin C and Type 2 Diabetes: Genome-Wide Association Study and Mendelian Randomization Analysis in European Populations.

Zheng JS, Luan J, Sofianopoulou E, Imamura F, Stewart ID, Day FR, Pietzner M, Wheeler E, Lotta LA, Gundersen TE, Amiano P, Ardanaz E, Chirlaque MD, Fagherazzi G, Franks PW, Kaaks R, Laouali N, Mancini FR, Nilsson PM, Onland-Moret NC, Olsen A, Overvad K, Panico S, Palli D, Ricceri F, Rolandsson O, Spijkerman AMW, Sánchez MJ, Schulze MB, Sala N, Sieri S, Tjønneland A, Tumino R, van der Schouw YT, Weiderpass E, Riboli E, Danesh J, Butterworth AS, Sharp SJ, Langenberg C, Forouhi NG, Wareham NJ

Diabetes care Jun 2020

(DOI : 10.2337/dc20-1328)

Genetic association study of childhood aggression across raters, instruments, and age.

Ip HF, van der Laan CM, Krapohl EML, Brikell I, Sánchez-Mora C, Nolte IM, St Pourcain B, Bolhuis K, Palviainen T, Zafarmand H, Colodro-Conde L, Gordon S, Zayats T, Aliev F, Jiang C, Wang CA, Saunders G, Karhunen V, Hammerschlag AR, Adkins DE, Border R, Peterson RE, Prinz JA, Thiering E, Seppala I, Vilor-Tejedor N, Ahluwalia TS, Day FR, Hottenga JJ, Allegrini AG, Rimfeld K, Chen Q, Lu Y, Martin J, Soler Artigas M, Rovira P, Bosch R, Español G, Ramos Quiroga JA, Neumann A, Ensink J, Grasby K, Morosoli JJ, Tong X, Marrington S, Middeldorp C, Scott JG, Vinkhuyzen A, Shabalin AA, Corley R, Evans LM, Sugden K, Alemany S, Sass L, Vinding R, Ruth K, Tyrrell J, Davies GE, Ehli EA, Hagenbeek FA, De Zeeuw E, Van Beijsterveldt TCEM, Larsson H, Snieder H, Verhulst FC, Amin N, Whipp AM, Korhonen T, Vuoksimaa E, Rose RJ, Uitterlinden AG, Heath AC, Madden P, Haavik J, Harris JR, Helgeland Ø, Johansson S, Knudsen GPS, Njolstad PR, Lu Q, Rodriguez A, Henders AK, Mamun A, Najman JM, Brown S, Hopfer C, Krauter K, Reynolds C, Smolen A, Stallings M, Wadsworth S, Wall TL, Silberg JL, Miller A, Keltikangas-Järvinen L, Hakulinen C, Pulkki-Råback L, Havdahl A, Magnus P, Raitakari OT, Perry JRB, Llop S, Lopez-Espinosa MJ, Bønnelykke K, Bisgaard H, Sunyer J, Lehtimäki T, Arseneault L, Standl M, Heinrich J, Boden J, Pearson J, Horwood LJ, Kennedy M, Poulton R, Eaves LJ, Maes HH, Hewitt J, Copeland WE, Costello EJ, Williams GM, Wray N, Järvelin MR, McGue M, Iacono W, Caspi A, Moffitt TE, Whitehouse A, Pennell CE, Klump KL, Burt SA, Dick DM, Reichborn-Kjennerud T, Martin NG, Medland SE, Vrijkotte T, Kaprio J, Tiemeier H, Davey Smith G, Hartman CA, Oldehinkel AJ, Casas M, Ribases M, Lichtenstein P, Lundström S, Plomin R, Bartels M, Nivard MG, Boomsma DI

Translational psychiatry May 2020

(DOI : 10.1038/s41398-021-01480-x)

Which infancy growth parameters are associated with later adiposity? The Cambridge Baby Growth Study.

Ong KK, Cheng TS, Olga L, Prentice PM, Petry CJ, Hughes IA, Dunger DB

Annals of human biology May 2020

(DOI : 10.1080/03014460.2020.1745887)

Identification of a unique epigenetic profile in women with diminished ovarian reserve.

Olsen KW, Castillo-Fernandez J, Chan AC, la Cour Freiesleben N, Zedeler A, Bungum M, Cardona A, Perry JRB, Skouby SO, Hoffmann ER, Kelsey G, Grøndahl ML

Fertility and sterility May 2020

(DOI : 10.1016/j.fertnstert.2020.09.009)

Genetic analyses identify widespread sex-differential participation bias.

Pirastu N, Cordioli M, Nandakumar P, Mignogna G, Abdellaoui A, Hollis B, Kanai M, Rajagopal VM, Parolo PDB, Baya N, Carey CE, Karjalainen J, Als TD, van der Zee MD, Day FR, Ong KK, FinnGen Study, 23andMe Research Team, iPSYCH Consortium, Morisaki T, de Geus E, Bellocco R, Okada Y, Børglum AD, Joshi P, Auton A, Hinds D, Neale BM, Walters RK, Nivard MG, Perry JRB, Ganna A

Nature genetics Mar 2020

(DOI : 10.1038/s41588-021-00846-7)

Duration of obesity exposure between ages 10 and 40 years and its relationship with cardiometabolic disease risk factors: A cohort study.

Norris T, Cole TJ, Bann D, Hamer M, Hardy R, Li L, Ong KK, Ploubidis GB, Viner R, Johnson W

PLoS Medicine Mar 2020

(DOI : 10.1371/journal.pmed.1003387)

The NEMP family supports metazoan fertility and nuclear envelope stiffness.

Tsatskis Y, Rosenfeld R, Pearson JD, Boswell C, Qu Y, Kim K, Fabian L, Mohammad A, Wang X, Robson MI, Krchma K, Wu J, Gonçalves J, Hodzic D, Wu S, Potter D, Pelletier L, Dunham WH, Gingras AC, Sun Y, Meng J, Godt D, Schedl T, Ciruna B, Choi K, Perry JRB, Bremner R, Schirmer EC, Brill JA, Jurisicova A, McNeill H

Science advances Feb 2020

(DOI : 10.1126/sciadv.abb4591)

Identification of nutritionally modifiable hormonal and epigenetic drivers of positive and negative growth deviance in rural African fetuses and infants: Project protocol and cohort description.

Moore SE, Doel AM, Ong KK, Dunger DB, Affara NA, Prentice AM, Bernstein RM, HERO-G Working Group HERO-G Working Group

Gates open research Feb 2020

(DOI : 10.12688/gatesopenres.13101.1)

Age at menarche associated with subsequent educational attainment and risk-taking behaviours: the Pelotas 1982 Birth Cohort.

Calthorpe LM, Gigante DP, Horta BL, Ong KK

Annals of human biology Feb 2020

(DOI : 10.1080/03014460.2020.1715476)

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, Grallert H, Perry JRB, Bouatia-Naji N, Marullo L, Rybin D, Jansen R, Min JL, Dimas AS, Ulrich A, Zudina L, Gådin JR, Jiang L, Faggian A, Bonnefond A, Fadista J, Stathopoulou MG, Isaacs A, Willems SM, Navarro P, Tanaka T, Jackson AU, Montasser ME, O'Connell JR, Bielak LF, Webster RJ, Saxena R, Stafford JM, Pourcain BS, Timpson NJ, Salo P, Shin SY, Amin N, Smith AV, Li G, Verweij N, Goel A, Ford I, Johnson PCD, Johnson T, Kapur K, Thorleifsson G, Strawbridge RJ, Rasmussen-Torvik LJ, Esko T, Mihailov E, Fall T, Fraser RM, Mahajan A, Kanoni S, Giedraitis V, Kleber ME, Silbernagel G, Meyer J, Müller-Nurasyid M, Ganna A, Sarin AP, Yengo L, Shungin D, Luan J, Horikoshi M, An P, Sanna S, Boettcher Y, Rayner NW, Nolte IM, Zemunik T, Iperen EV, Kovacs P, Hastie ND, Wild SH, McLachlan S, Campbell S, Polasek O, Carlson O, Egan J, Kiess W, Willemsen G, Kuusisto J, Laakso M, Dimitriou M, Hicks AA, Rauramaa R, Bandinelli S, Thorand B, Liu Y, Miljkovic I, Lind L, Doney A, Perola M, Hingorani A, Kivimaki M, Kumari M, Bennett AJ, Groves CJ, Herder C, Koistinen HA, Kinnunen L, Faire U, Bakker SJL, Uusitupa M, Palmer CNA, Jukema JW, Sattar N, Pouta A, Snieder H, Boerwinkle E, Pankow JS, Magnusson PK, Krus U, Scapoli C, de Geus EJCN, Blüher M, Wolffenbuttel BHR, Province MA, Abecasis GR, Meigs JB, Hovingh GK, Lindström J, Wilson JF, Wright AF, Dedoussis GV, Bornstein SR, Schwarz PEH, Tönjes A, Winkelmann BR, Boehm BO, März W, Metspalu A, Price JF, Deloukas P, Körner A, Lakka TA, Keinanen-Kiukaanniemi SM, Saaristo TE, Bergman RN, Tuomilehto J, Wareham NJ, Langenberg C, Männistö S, Franks PW, Hayward C, Vitart V, Kaprio J, Visvikis-Siest S, Balkau B, Altshuler D, Rudan I, Stumvoll M, Campbell H, van Duijn CM, Gieger C, Illig T, Ferrucci L, Pedersen NL, Pramstaller PP, Boehnke M, Frayling TM, Shuldiner AR, Peyser PA, Kardia SLR, Palmer LJ, Penninx BW, Meneton P, Harris TB, Navis G, Harst PV, Smith GD, Forouhi NG, Loos RJF, Salomaa V, Soranzo N, Boomsma DI, Groop L, Tuomi T, Hofman A, Munroe PB, Gudnason V, Siscovick DS, Watkins H, Lecoeur C, Vollenweider P, Franco-Cereceda A, Eriksson P, Järvelin MR, Stefansson K, Hamsten A, Nicholson G, Karpe F, Dermitzakis ET, Lindgren CM, McCarthy MI, Froguel P, Kaakinen MA, Lyssenko V, Watanabe RM, Ingelsson E, Florez JC, Dupuis J, Barroso I, Morris AP, Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nature communications Jan 2020

(DOI : 10.1038/s41467-020-19366-9)

Timing of the Infancy-Childhood Growth Transition in Rural Gambia.

Bernstein RM, O'Connor GK, Vance EA, Affara N, Drammeh S, Dunger DB, Faal A, Ong KK, Sosseh F, Prentice AM, Moore SE

Frontiers in endocrinology Dec 2019

(DOI : 10.3389/fendo.2020.00142)

The potential shared role of inflammation in insulin resistance and schizophrenia: A bidirectional two-sample mendelian randomization study.

Perry BI, Burgess S, Jones HJ, Zammit S, Upthegrove R, Mason AM, Day FR, Langenberg C, Wareham NJ, Jones PB, Khandaker GM

PLoS Medicine Nov 2019

(DOI : 10.1371/journal.pmed.1003455)

The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice.

Shreeve N, Depierreux D, Hawkes D, Traherne JA, Sovio U, Huhn O, Jayaraman J, Horowitz A, Ghadially H, Perry JRB, Moffett A, Sled JG, Sharkey AM, Colucci F

Immunity Oct 2019

(DOI : 10.1016/j.immuni.2021.03.021)

Positive maternal attitudes to following healthy infant feeding guidelines attenuate the associations between infant appetitive traits and both infant milk intake and weight.

Clifton EAD, Ahern AL, Day FR, Sharp SJ, Griffin SJ, Ong KK, Rajalakshmi Lakshman

Appetite Oct 2019

(DOI : 10.1016/j.appet.2021.105124)

A distinctive epigenetic ageing profile in human granulosa cells.

Olsen KW, Castillo-Fernandez J, Zedeler A, Freiesleben NC, Bungum M, Chan AC, Cardona A, Perry JRB, Skouby SO, Borup R, Hoffmann ER, Kelsey G, Grøndahl ML

Human reproduction (Oxford, England) Sep 2019

(DOI : 10.1093/humrep/deaa071)

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.

Sikdar S, Joehanes R, Joubert BR, Xu CJ, Vives-Usano M, Rezwan FI, Felix JF, Ward JM, Guan W, Richmond RC, Brody JA, Küpers LK, Baïz N, Håberg SE, Smith JA, Reese SE, Aslibekyan S, Hoyo C, Dhingra R, Markunas CA, Xu T, Reynolds LM, Just AC, Mandaviya PR, Ghantous A, Bennett BD, Wang T, Consortium TB, Bakulski KM, Melén E, Zhao S, Jin J, Herceg Z, Meurs JV, Taylor JA, Baccarelli AA, Murphy SK, Liu Y, Munthe-Kaas MC, Deary IJ, Nystad W, Waldenberger M, Annesi-Maesano I, Conneely K, Jaddoe VW, Arnett D, Snieder H, Kardia SL, Relton CL, Ong KK, Ewart S, Moreno-Macias H, Romieu I, Sotoodehnia N, Fornage M, Motsinger-Reif A, Koppelman GH, Bustamante M, Levy D, London SJ

Epigenomics Sep 2019

(DOI : 10.2217/epi-2019-0066)

Genetic basis of falling risk susceptibility in the UK Biobank Study.

Trajanoska K, Seppala LJ, Medina-Gomez C, Hsu YH, Zhou S, van Schoor NM, de Groot LCPGM, Karasik D, Richards JB, Kiel DP, Uitterlinden AG, Perry JRB, van der Velde N, Day FR, Rivadeneira F

Communications biology Sep 2019

(DOI : 10.1038/s42003-020-01256-x)

Using human genetics to understand the disease impacts of testosterone in men and women.

Ruth KS, Day FR, Tyrrell J, Thompson DJ, Wood AR, Mahajan A, Beaumont RN, Wittemans L, Martin S, Busch AS, Erzurumluoglu AM, Hollis B, O'Mara TA, Endometrial Cancer Association Consortium, McCarthy MI, Langenberg C, Easton DF, Wareham NJ, Burgess S, Murray A, Ong KK, Frayling TM, Perry JRB

Nature medicine Sep 2019

(DOI : 10.1038/s41591-020-0751-5)

The association between circulating 25-hydroxyvitamin D metabolites and type 2 diabetes in European populations: A meta-analysis and Mendelian randomisation analysis.

Zheng JS, Luan J, Sofianopoulou E, Sharp SJ, Day FR, Imamura F, Gundersen TE, Lotta LA, Sluijs I, Stewart ID, Shah RL, van der Schouw YT, Wheeler E, Ardanaz E, Boeing H, Dorronsoro M, Dahm CC, Dimou N, El-Fatouhi D, Franks PW, Fagherazzi G, Grioni S, Huerta JM, Heath AK, Hansen L, Jenab M, Jakszyn P, Kaaks R, Kühn T, Khaw KT, Laouali N, Masala G, Nilsson PM, Overvad K, Olsen A, Panico S, Quirós JR, Rolandsson O, Rodriguez-Barranco M, Sacerdote C, Spijkerman AMW, Tong TYN, Tumino R, Tsilidis KK, Danesh J, Riboli E, Butterworth AS, Langenberg C, Forouhi NG, Wareham NJ

PLoS Medicine Sep 2019

(DOI : 10.1371/journal.pmed.1003394)

Temporal Trends in Maternal Food Intake Frequencies and Associations with Gestational Diabetes: The Cambridge Baby Growth Study.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Nutrients Sep 2019

(DOI : 10.3390/nu11112822)

Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism.

Furse S, Snowden SG, Olga L, Prentice P, Ong KK, Hughes IA, Acerini CL, Dunger DB, Koulman A

Scientific reports Jun 2019

(DOI : 10.1038/s41598-019-50693-0)

Association of puberty timing with type 2 diabetes: A systematic review and meta-analysis.

Cheng TS, Day FR, Lakshman R, Ong KK

PLoS Medicine Jun 2019

(DOI : 10.1371/journal.pmed.1003017)

Maternal serum concentrations of bisphenol A and propyl paraben in early pregnancy are associated with male infant genital development.

Fisher BG, Thankamony A, Mendiola J, Petry CJ, Frederiksen H, Andersson AM, Juul A, Ong KK, Dunger DB, Hughes IA, Acerini CL

Human reproduction (Oxford, England) Apr 2019

(DOI : 10.1093/humrep/deaa045)

Temporal trends without seasonal effects on gestational diabetes incidence relate to reductions in indices of insulin secretion: the Cambridge Baby Growth Study.

Petry CJ, Fisher BG, Ong KK, Hughes IA, Acerini CL, Dunger DB

Acta diabetologica Apr 2019

(DOI : 10.1007/s00592-019-01354-1)

Voice break in boys-temporal relations with other pubertal milestones and likely causal effects of BMI.

Busch AS, Hollis B, Day FR, Sørensen K, Aksglaede L, Perry JR, Ong KK, Juul A, Hagen CP

Human reproduction (Oxford, England) Mar 2019

(DOI : 10.1093/humrep/dez118)

DNA methylation age and physical and cognitive ageing.

Maddock J, Castillo-Fernandez J, Wong A, Cooper R, Richards M, Ong KK, Ploubidis GB, Goodman A, Kuh D, Bell JT, Hardy R

The journals of gerontology. Series A, Biological sciences and medical sciences Mar 2019

(DOI : 10.1093/gerona/glz246)

Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis.

Gallagher CS, Mäkinen N, Harris HR, Rahmioglu N, Uimari O, Cook JP, Shigesi N, Ferreira T, Velez-Edwards DR, Edwards TL, Mortlock S, Ruhioglu Z, Day F, Becker CM, Karhunen V, Martikainen H, Järvelin MR, Cantor RM, Ridker PM, Terry KL, Buring JE, Gordon SD, Medland SE, Montgomery GW, Nyholt DR, Hinds DA, Tung JY, 23andMe Research Team, Perry JR, Lind PA, Painter JN, Martin NG, Morris AP, Chasman DI, Missmer SA, Zondervan KT, Morton CC

Nature communications Feb 2019

(DOI : 10.1038/s41467-019-12536-4)

Age at Menarche and Blood Pressure in Pregnancy.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Pregnancy hypertension Feb 2019

(DOI : 10.1016/j.preghy.2019.01.004)

Reduced size at birth and persisting reductions in adiposity in recent, compared with earlier, cohorts of infants born to mothers with gestational diabetes mellitus.

Prentice PM, Olga L, Petry CJ, Simmons D, Murphy HR, Hughes IA, Acerini CL, Ong KK, Dunger DB

Diabetologia Jan 2019

(DOI : 10.1007/s00125-019-4970-6)

Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.

Lotta LA, Mokrosiński J, Mendes de Oliveira E, Li C, Sharp SJ, Luan J, Brouwers B, Ayinampudi V, Bowker N, Kerrison N, Kaimakis V, Hoult D, Stewart ID, Wheeler E, Day FR, Perry JRB, Langenberg C, Wareham NJ, Farooqi IS

Cell Dec 2018

(DOI : 10.1016/j.cell.2019.03.044)

Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.

Lotta LA, Wittemans LBL, Zuber V, Stewart ID, Sharp SJ, Luan J, Day FR, Li C, Bowker N, Cai L, De Lucia Rolfe E, Khaw KT, Perry JRB, O'Rahilly S, Scott RA, Savage DB, Burgess S, Wareham NJ, Langenberg C

JAMA Dec 2018

(DOI : 10.1001/jama.2018.19329)

GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI.

Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, Taal HR, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, Thiering E, Timpson NJ, Bond TA, Lowry E, Brown CD, Estivill X, Lindi V, Bradfield JP, Geller F, Speed D, Coin LJM, Loh M, Barton SJ, Beilin LJ, Bisgaard H, Bønnelykke K, Alili R, Hatoum IJ, Schramm K, Cartwright R, Charles MA, Salerno V, Clément K, Claringbould AAJ, BIOS Consortium, van Duijn CM, Moltchanova E, Eriksson JG, Elks C, Feenstra B, Flexeder C, Franks S, Frayling TM, Freathy RM, Elliott P, Widén E, Hakonarson H, Hattersley AT, Rodriguez A, Banterle M, Heinrich J, Heude B, Holloway JW, Hofman A, Hyppönen E, Inskip H, Kaplan LM, Hedman ÅK, Läärä E, Prokisch H, Grallert H, Lakka TA, Lawlor DA, Melbye M, Ahluwalia TS, Marinelli M, Millwood IY, Palmer LJ, Pennell CE, Perry JR, Ring SM, Savolainen MJ, Rivadeneira F, Standl M, Sunyer J, Tiesler CMT, Uitterlinden AG, Schierding W, O'Sullivan JM, Prokopenko I, Herzig KH, Smith GD, O'Reilly P, Felix JF, Buxton JL, Blakemore AIF, Ong KK, Jaddoe VWV, Grant SFA, Sebert S, McCarthy MI, Järvelin MR, Early Growth Genetics (EGG) Consortium

Science advances Dec 2018

(DOI : 10.1126/sciadv.aaw3095)

Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan.

Hollis B, Day FR, Busch AS, Thompson DJ, Soares ALG, Timmers PRHJ, Kwong A, Easton DF, Joshi PK, Timpson NJ, PRACTICAL Consortium, 23andMe Research Team, Ong KK, Perry JRB

Nature communications Nov 2018

(DOI : 10.1038/s41467-020-14451-5)

Associations of autozygosity with a broad range of human phenotypes.

Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, Zhang W, Medina-Gomez C, Karlsson R, Bao Y, Bartz TM, Baumbach C, Biino G, Bixley MJ, Brumat M, Chai JF, Corre T, Cousminer DL, Dekker AM, Eccles DA, van Eijk KR, Fuchsberger C, Gao H, Germain M, Gordon SD, de Haan HG, Harris SE, Hofer E, Huerta-Chagoya A, Igartua C, Jansen IE, Jia Y, Kacprowski T, Karlsson T, Kleber ME, Li SA, Li-Gao R, Mahajan A, Matsuda K, Meidtner K, Meng W, Montasser ME, van der Most PJ, Munz M, Nutile T, Palviainen T, Prasad G, Prasad RB, Priyanka TDS, Rizzi F, Salvi E, Sapkota BR, Shriner D, Skotte L, Smart MC, Smith AV, van der Spek A, Spracklen CN, Strawbridge RJ, Tajuddin SM, Trompet S, Turman C, Verweij N, Viberti C, Wang L, Warren HR, Wootton RE, Yanek LR, Yao J, Yousri NA, Zhao W, Adeyemo AA, Afaq S, Aguilar-Salinas CA, Akiyama M, Albert ML, Allison MA, Alver M, Aung T, Azizi F, Bentley AR, Boeing H, Boerwinkle E, Borja JB, de Borst GJ, Bottinger EP, Broer L, Campbell H, Chanock S, Chee ML, Chen G, Chen YI, Chen Z, Chiu YF, Cocca M, Collins FS, Concas MP, Corley J, Cugliari G, van Dam RM, Damulina A, Daneshpour MS, Day FR, Delgado GE, Dhana K, Doney ASF, Dörr M, Doumatey AP, Dzimiri N, Ebenesersdóttir SS, Elliott J, Elliott P, Ewert R, Felix JF, Fischer K, Freedman BI, Girotto G, Goel A, Gögele M, Goodarzi MO, Graff M, Granot-Hershkovitz E, Grodstein F, Guarrera S, Gudbjartsson DF, Guity K, Gunnarsson B, Guo Y, Hagenaars SP, Haiman CA, Halevy A, Harris TB, Hedayati M, van Heel DA, Hirata M, Höfer I, Hsiung CA, Huang J, Hung YJ, Ikram MA, Jagadeesan A, Jousilahti P, Kamatani Y, Kanai M, Kerrison ND, Kessler T, Khaw KT, Khor CC, de Kleijn DPV, Koh WP, Kolcic I, Kraft P, Krämer BK, Kutalik Z, Kuusisto J, Langenberg C, Launer LJ, Lawlor DA, Lee IT, Lee WJ, Lerch MM, Li L, Liu J, Loh M, London SJ, Loomis S, Lu Y, Luan J, Mägi R, Manichaikul AW, Manunta P, Masson G, Matoba N, Mei XW, Meisinger C, Meitinger T, Mezzavilla M, Milani L, Millwood IY, Momozawa Y, Moore A, Morange PE, Moreno-Macias H, Mori TA, Morrison AC, Muka T, Murakami Y, Murray AD, de Mutsert R, Mychaleckyj JC, Nalls MA, Nauck M, Neville MJ, Nolte IM, Ong KK, Orozco L, Padmanabhan S, Pálsson G, Pankow JS, Pattaro C, Pattie A, Polasek O, Poulter N, Pramstaller PP, Quintana-Murci L, Räikkönen K, Ralhan S, Rao DC, van Rheenen W, Rich SS, Ridker PM, Rietveld CA, Robino A, van Rooij FJA, Ruggiero D, Saba Y, Sabanayagam C, Sabater-Lleal M, Sala CF, Salomaa V, Sandow K, Schmidt H, Scott LJ, Scott WR, Sedaghati-Khayat B, Sennblad B, van Setten J, Sever PJ, Sheu WH, Shi Y, Shrestha S, Shukla SR, Sigurdsson JK, Sikka TT, Singh JR, Smith BH, Stančáková A, Stanton A, Starr JM, Stefansdottir L, Straker L, Sulem P, Sveinbjornsson G, Swertz MA, Taylor AM, Taylor KD, Terzikhan N, Tham YC, Thorleifsson G, Thorsteinsdottir U, Tillander A, Tracy RP, Tusie-Luna T, Tzoulaki I, Vaccargiu S, Vangipurapu J, Veldink JH, Vitart V, Völker U, Vuoksimaa E, Wakil SM, Waldenberger M, Wander GS, Wang YX, Wareham NJ, Wild S, Yajnik CS, Yuan JM, Zeng L, Zhang L, Zhou J, Amin N, Asselbergs FW, Bakker SJL, Becker DM, Lehne B, Bennett DA, van den Berg LH, Berndt SI, Bharadwaj D, Bielak LF, Bochud M, Boehnke M, Bouchard C, Bradfield JP, Brody JA, Campbell A, Carmi S, Caulfield MJ, Cesarini D, Chambers JC, Chandak GR, Cheng CY, Ciullo M, Cornelis M, Cusi D, Smith GD, Deary IJ, Dorajoo R, van Duijn CM, Ellinghaus D, Erdmann J, Eriksson JG, Evangelou E, Evans MK, Faul JD, Feenstra B, Feitosa M, Foisy S, Franke A, Friedlander Y, Gasparini P, Gieger C, Gonzalez C, Goyette P, Grant SFA, Griffiths LR, Groop L, Gudnason V, Gyllensten U, Hakonarson H, Hamsten A, van der Harst P, Heng CK, Hicks AA, Hochner H, Huikuri H, Hunt SC, Jaddoe VWV, De Jager PL, Johannesson M, Johansson Å, Jonas JB, Jukema JW, Junttila J, Kaprio J, Kardia SLR, Karpe F, Kumari M, Laakso M, Van Der Laan SW, Lahti J, Laudes M, Lea RA, Lieb W, Lumley T, Martin NG, März W, Matullo G, McCarthy MI, Medland SE, Merriman TR, Metspalu A, Meyer BF, Mohlke KL, Montgomery GW, Mook-Kanamori D, Munroe PB, North KE, Nyholt DR, O'Connell JR, Ober C, Oldehinkel AJ, Palmas W, Palmer C, Pasterkamp GG, Patin E, Pennell CE, Pérusse L, Peyser PA, Pirastu M, Polderman TJC, Porteous DJ, Posthuma D, Psaty BM, Rioux JD, Rivadeneira F, Rotimi C, Rotter JI, Rudan I, den Ruijter HM, Sanghera DK, Sattar N, Schmidt R, Schulze MB, Schunkert H, Scott RA, Shuldiner AR, Sim X, Small N, Smith JA, Sotoodehnia N, Tai ES, Teumer A, Timpson NJ, Toniolo D, Trégouët DA, Tuomi T, Vollenweider P, Wang CA, Weir DR, Whitfield JB, Wijmenga C, Wong TY, Wright J, Yang J, Yu L, Zemel BS, Zonderman AB, Perola M, Magnusson PKE, Uitterlinden AG, Kooner JS, Chasman DI, Loos RJF, Franceschini N, Franke L, Haley CS, Hayward C, Walters RG, Perry JR, Esko T, Helgason A, Stefansson K, Joshi PK, Kubo M, Wilson JF

Nature communications Nov 2018

(DOI : 10.1038/s41467-019-12283-6)

Systematic review and meta-analysis of the association between childhood physical activity and age at menarche.

Calthorpe L, Brage S, Ong KK

Acta paediatrica (Oslo, Norway : 1992) Oct 2018

(DOI : 10.1111/apa.14711)

The influence of maternal pregnancy glucose concentrations on associations between a fetal imprinted gene allele score and offspring size at birth.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

BMC research notes Oct 2018

(DOI : 10.1186/s13104-018-3933-1)

Association of Genetically Enhanced Lipoprotein Lipase-Mediated Lipolysis and Low-Density Lipoprotein Cholesterol-Lowering Alleles With Risk of Coronary Disease and Type 2 Diabetes.

Lotta LA, Stewart ID, Sharp SJ, Day FR, Burgess S, Luan J, Bowker N, Cai L, Li C, Wittemans LBL, Kerrison ND, Khaw KT, McCarthy MI, O'Rahilly S, Scott RA, Savage DB, Perry JRB, Langenberg C, Wareham NJ

JAMA cardiology Oct 2018

(DOI : 10.1001/jamacardio.2018.2866)

Associations of physical activity and sedentary time with body composition in Brazilian young adults.

Silva BGCD, Silva ICMD, Ekelund U, Brage S, Ong KK, De Lucia Rolfe E, Lima NP, Silva SGD, França GVA, Horta BL

Scientific reports Sep 2018

(DOI : 10.1038/s41598-019-41935-2)

Human Milk Short-Chain Fatty Acid Composition is Associated with Adiposity Outcomes in Infants.

Schoemaker MH, Acerini CL, Hughes IA, Koulman A, Ong KK, Dunger DB

The Journal of nutrition Sep 2018

(DOI : 10.1093/jn/nxy320)

Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study.

Petry CJ, Ong KK, Burling KA, Barker P, Goodburn SF, Perry JRB, Acerini CL, Hughes IA, Painter RC, Afink GB, Dunger DB, O'Rahilly S

Wellcome open research Sep 2018

(DOI : 10.12688/wellcomeopenres.14818.1)

Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior.

Ganna A, Verweij KJH, Nivard MG, Maier R, Wedow R, Busch AS, Abdellaoui A, Guo S, Sathirapongsasuti JF, 23andMe Research Team, Lichtenstein P, Lundström S, Långström N, Auton A, Harris KM, Beecham GW, Martin ER, Sanders AR, Perry JR, Neale BM, Zietsch BP

Science (New York, N.Y.) Sep 2018

(DOI : 10.1126/science.aat7693)

Relative effects of postnatal rapid growth and maternal factors on early childhood growth trajectories.

Zheng M, Bowe SJ, Hesketh KD, Bolton K, Laws R, Kremer P, Ong KK, Lioret S, Denney-Wilson E, Campbell KJ

Paediatric and perinatal epidemiology Aug 2018

(DOI : 10.1111/ppe.12541)

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

Lee JJ, Wedow R, Okbay A, Kong E, Maghzian O, Zacher M, Nguyen-Viet TA, Bowers P, Sidorenko J, Karlsson Linnér R, Fontana MA, Kundu T, Lee C, Li H, Li R, Royer R, Timshel PN, Walters RK, Willoughby EA, Yengo L, 23andMe Research Team, COGENT (Cognitive Genomics Consortium), Social Science Genetic Association Consortium, Alver M, Bao Y, Clark DW, Day FR, Furlotte NA, Joshi PK, Kemper KE, Kleinman A, Langenberg C, Mägi R, Trampush JW, Verma SS, Wu Y, Lam M, Zhao JH, Zheng Z, Boardman JD, Campbell H, Freese J, Harris KM, Hayward C, Herd P, Kumari M, Lencz T, Luan J, Malhotra AK, Metspalu A, Milani L, Ong KK, Perry JRB, Porteous DJ, Ritchie MD, Smart MC, Smith BH, Tung JY, Wareham NJ, Wilson JF, Beauchamp JP, Conley DC, Esko T, Lehrer SF, Magnusson PKE, Oskarsson S, Pers TH, Robinson MR, Thom K, Watson C, Chabris CF, Meyer MN, Laibson DI, Yang J, Johannesson M, Koellinger PD, Turley P, Visscher PM, Benjamin DJ, Cesarini D

Nature genetics Aug 2018

(DOI : 10.1038/s41588-018-0147-3)

Maternal traditional dietary pattern and antiretroviral treatment exposure are associated with neonatal size and adiposity in urban, black South Africans.

Wrottesley SV, Ong KK, Pisa PT, Norris SA

The British journal of nutrition Jul 2018

(DOI : 10.1017/S0007114518001708)

Adolescent parenthood associated with adverse socio-economic outcomes at age 30 years in women and men of the Pelotas, Brazil: 1982 Birth Cohort Study.

Gigante DP, de França G, De Lucia Rolfe E, Lima NP, Dos Santos Motta JV, Gonçalves H, Horta BL, Barros FC, Ong KK

BJOG : an international journal of obstetrics and gynaecology Jul 2018

(DOI : 10.1111/1471-0528.15428)

Assessing the causal association of glycine with risk of cardio-metabolic diseases.

Wittemans LBL, Lotta LA, Oliver-Williams C, Stewart ID, Surendran P, Karthikeyan S, Day FR, Koulman A, Imamura F, Zeng L, Erdmann J, Schunkert H, Khaw KT, Griffin JL, Forouhi NG, Scott RA, Wood AM, Burgess S, Howson JMM, Danesh J, Wareham NJ, Butterworth AS, Langenberg C

Nature communications Jul 2018

(DOI : 10.1038/s41467-019-08936-1)

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, Chen J, Nodzenski M, Schnurr TM, Zafarmand MH, Bradfield JP, Grarup N, Kooijman MN, Li-Gao R, Geller F, Ahluwalia TS, Paternoster L, Rueedi R, Huikari V, Hottenga JJ, Lyytikäinen LP, Cavadino A, Cousminer DL, Thiering E, Wang CA, Have CT, Vilor-Tejedor N, Joshi PK, Painter JN, Ntalla I, Myhre R, Pitkänen N, van Leeuwen EM, Joro R, Lagou V, Barton SJ, Inskip HM, Holloway JW, Marullo L, Lunetta KL, Murabito JM, Relton CL, Hivert MF, Mentch FD, Langenberg C, Luan J, Scott RA, Zhao JH, Hemani G, Ring SM, Bennett AJ, Gaulton KJ, Fernandez-Tajes J, van Zuydam NR, Medina-Gomez C, de Haan HG, Rosendaal FR, Kutalik Z, Marques-Vidal P, Willemsen G, Mbarek H, Müller-Nurasyid M, Standl M, Appel EVR, Fonvig CE, Trier C, Murcia M, Bustamante M, Bonas-Guarch S, Hougaard DM, Mercader JM, Linneberg A, Schraut KE, Lind PA, Medland SE, Chai JF, Panoutsopoulou K, Sánchez F, Torrents D, Willems S, Atalay M, Kovacs P, Prokopenko I, Tuke MA, Yaghootkar H, Ruth KS, Jones SE, Loh PR, Murray A, Weedon MN, Tönjes A, Stumvoll M, Lakka TA, van Duijn CM, Kiess W, Körner A, Niinikoski H, Pahkala K, Raitakari OT, Jacobsson B, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Montgomery GW, Campbell H, Wilson JF, Vrijheid M, de Geus EJCN, Kadarmideen HN, Holm JC, Beilin LJ, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Hattersley AT, Spector TD, Kähönen M, Viikari JS, Lehtimäki T, Boomsma DI, Sebert S, Vollenweider P, Sørensen TIA, Bisgaard H, Bønnelykke K, Murray JC, Melbye M, Nohr EA, Mook-Kanamori DO, Rivadeneira F, Hofman A, Felix JF, Jaddoe VWV, Hansen T, Pisinger C, Vaag AA, Pedersen O, Uitterlinden AG, Järvelin MR, Power C, Hyppönen E, Scholtens DM, Lowe WL, Davey Smith G, Timpson NJ, Morris AP, Wareham NJ, Hakonarson H, Grant SFA, Frayling TM, Lawlor DA, Njølstad PR, Johansson S, Ong KK, McCarthy MI, Perry JR, Evans DM, Freathy RM

Nature genetics Jun 2018

(DOI : 10.1038/s41588-019-0403-1)

Age at menarche and the future risk of gestational diabetes: a systematic review and dose response meta-analysis.

Petry CJ, Ong KK, Dunger DB

Acta diabetologica Jun 2018

(DOI : 10.1007/s00592-018-1214-z)

Associations between the maternal circulating lipid profile in pregnancy and fetal imprinted gene alleles: a cohort study.

Petry CJ, Koulman A, Lu L, Jenkins B, Furse S, Prentice P, Matthews L, Hughes IA, Acerini CL, Ong KK, Dunger DB

Reproductive biology and endocrinology : RB&E Jun 2018

(DOI : 10.1186/s12958-018-0399-x)

Association between genetic obesity susceptibility and mother-reported eating behaviour in children up to 5 years.

de Lauzon-Guillain B, Koudou YA, Botton J, Forhan A, Carles S, Pelloux V, Clément K, Ong KK, Charles MA, Heude B, EDEN Mother-Child Cohort Study Group

Pediatric Obesity May 2018

(DOI : 10.1111/ijpo.12496)

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.

Day F, Karaderi T, Jones MR, Meun C, He C, Drong A, Kraft P, Lin N, Huang H, Broer L, Mägi R, Saxena R, Laisk T, Urbanek M, Hayes MG, Thorleifsson G, Fernandez-Tajes J, Mahajan A, Mullin BH, Stuckey BGA, Spector TD, Wilson SG, Goodarzi MO, Davis L, Obermayer-Pietsch B, Uitterlinden AG, Anttila V, Neale BM, Järvelin MR, Fauser B, Kowalska I, Visser JA, Andersen M, Ong K, Stener-Victorin E, Ehrmann D, Legro RS, Salumets A, McCarthy MI, Morin-Papunen L, Thorsteinsdottir U, Stefansson K, 23andMe Research Team, Styrkarsdottir U, Perry JRB, Dunaif A, Laven J, Franks S, Lindgren CM, Welt CK

PLoS genetics Apr 2018

(DOI : 10.1371/journal.pgen.1007813)

Validity of ultrasonography to assess hepatic steatosis compared to magnetic resonance spectroscopy as a criterion method in older adults.

De Lucia Rolfe E, Brage S, Sleigh A, Finucane F, Griffin SJ, Wareham NJ, Ong KK, Forouhi NG

PLoS ONE Apr 2018

(DOI : 10.1371/journal.pone.0207923)

Toward Understanding How Social Factors Shaped a Behavioral Intervention on Healthier Infant Formula-Feeding.

Guell C, Whittle F, Ong KK, Lakshman R

Qualitative Health Research Mar 2018

(DOI : 10.1177/1049732318764386)

The association between age at menarche and later risk of gestational diabetes is mediated by insulin resistance.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Acta diabetologica Mar 2018

(DOI : 10.1007/s00592-018-1162-7)

Exploring the genetic correlations of antisocial behaviour and life history traits.

Tielbeek JJ, Barnes JC, Popma A, Polderman TJC, Lee JJ, Perry JRB, Posthuma D, Boutwell BB

BJPsych open Feb 2018

(DOI : 10.1192/bjo.2018.63)

The Influence of Maternal Obesity and Breastfeeding on Infant Appetite- and Growth-Related Hormone Concentrations: The SKOT Cohort Studies.

Larnkjær A, Ong KK, Carlsen EM, Ejlerskov KT, Mølgaard C, Michaelsen KF

Hormone research in paediatrics Jan 2018

(DOI : 10.1159/000490114)

GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.

Pasman JA, Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong JS, Ip HF, van der Zee MD, Bartels M, Day FR, Fontanillas P, Elson SL, 23andMe Research Team, de Wit H, Davis LK, MacKillop J, Substance Use Disorders Working Group of the Psychiatric Genomics Consortium, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Mägi R, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Ramos-Quiroga JA, Paus T, Ribases M, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Munafò MR, Gillespie NA, Derks EM, Vink JM

Nature neuroscience Jan 2018

(DOI : 10.1038/s41593-018-0206-1)

Randomised controlled trial of a theory-based behavioural intervention to reduce formula milk intake.

Lakshman R, Sharp SJ, Whittle F, Schiff A, Hardeman W, Irvine L, Wilson E, Griffin SJ, Ong KK

Archives of Disease in Childhood Jan 2018

(DOI : 10.1136/archdischild-2018-314784)

Identification of nine new susceptibility loci for endometrial cancer.

O'Mara TA, Attia J, Auer PL, Beckmann MW, Bolla MK, Brauch H, Brenner H, Burwinkel B, Chang-Claude J, Chanock SJ, Chen C, Couch FJ, Czene K, Dennis J, Dörk T, Fasching PA, García-Closas M, Giles GG, Haiman CA, Hall P, Holliday EG, Hopper JL, Hunter DJ, Kristensen VN, Lambrechts D, Marchand LL, Long J, Lu L, McEvoy M, Meindl A, Michailidou K, Milne RL, Montgomery GW, Orlow I, Perry JR, Peto J, Risch HA, Sacerdote C, Scott RJ, Shah M, Shu XO, Southey MC, Turman C, Tyrer JP, Wang Z, Wentzensen N, Xiang YB, Zheng W, Pharoah PDP, Dunning AM, Kraft P, De Vivo I, Tomlinson I, Easton DF, Spurdle AB, Thompson DJ

Nature communications Dec 2017

(DOI : 10.1038/s41467-018-05427-7)

Serum Phthalate and Triclosan Levels Have Opposing Associations With Risk Factors for Gestational Diabetes Mellitus.

Fisher BG, Frederiksen H, Andersson AM, Juul A, Thankamony A, Ong KK, Dunger DB, Hughes IA, Acerini CL

Frontiers in endocrinology Dec 2017

(DOI : 10.3389/fendo.2018.00099)

Genetic risk score for adult body mass index associations with childhood and adolescent weight gain in an African population.

Munthali RJ, Sahibdeen V, Kagura J, Hendry LM, Norris SA, Ong KK, Day FR, Lombard Z

Genes & nutrition Dec 2017

(DOI : 10.1186/s12263-018-0613-7)

Secular Trends on Birth Parameters, Growth, and Pubertal Timing in Girls with Turner Syndrome.

Woelfle J, Lindberg A, Aydin F, Ong KK, Camacho-Hubner C, Gohlke B

Frontiers in endocrinology Dec 2017

(DOI : 10.3389/fendo.2018.00054)

Elucidating the genetic basis of social interaction and isolation.

Day FR, Ong KK, Perry JR

Nature communications Nov 2017

(DOI : 10.1038/s41467-018-04930-1)

Effects of dietary intake patterns from 1 to 4 years on BMI z-score and body shape at age of 6 years: a prospective birth cohort study from Brazil.

Santos LP, Ong KK, Santos IS, Matijasevich A, Barros AJD

European journal of nutrition Nov 2017

(DOI : 10.1007/s00394-018-1720-3)

Breastfeeding moderates FTO related adiposity: a birth cohort study with 30 years of follow-up.

Horta BL, Victora CG, França GVA, Hartwig FP, Ong KK, Rolfe EL, Magalhães EIS, Lima NP, Barros FC

Scientific reports Oct 2017

(DOI : 10.1038/s41598-018-20939-4)

Genome-wide association study for risk taking propensity indicates shared pathways with body mass index.

Clifton EAD, Perry JRB, Imamura F, Lotta LA, Brage S, Forouhi NG, Griffin SJ, Wareham NJ, Ong KK, Day FR

Communications biology Oct 2017

(DOI : 10.1038/s42003-018-0042-6)

Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior.

Tielbeek JJ, Johansson Å, Polderman TJC, Rautiainen MR, Jansen P, Taylor M, Tong X, Lu Q, Burt AS, Tiemeier H, Viding E, Plomin R, Martin NG, Heath AC, Madden PAF, Montgomery G, Beaver KM, Waldman I, Gelernter J, Kranzler HR, Farrer LA, Perry JRB, Munafò M, LoParo D, Paunio T, Tiihonen J, Mous SE, Pappa I, de Leeuw C, Watanabe K, Hammerschlag AR, Salvatore JE, Aliev F, Bigdeli TB, Dick D, Faraone SV, Popma A, Medland SE, Posthuma D, Broad Antisocial Behavior Consortium collaborators

JAMA psychiatry Oct 2017

(DOI : 10.1001/jamapsychiatry.2017.3069)

The associations between adult body composition and abdominal adiposity outcomes, and relative weight gain and linear growth from birth to age 22 in the Birth to Twenty Plus cohort, South Africa.

Prioreschi A, Munthali RJ, Kagura J, Said-Mohamed R, De Lucia Rolfe E, Micklesfield LK, Norris SA

PLoS ONE Oct 2017

(DOI : 10.1371/journal.pone.0190483)

Identifying and correcting epigenetics measurements for systematic sources of variation.

Perrier F, Novoloaca A, Ambatipudi S, Baglietto L, Ghantous A, Perduca V, Barrdahl M, Harlid S, Ong KK, Cardona A, Polidoro S, Nøst TH, Overvad K, Omichessan H, Dollé M, Bamia C, Huerta JM, Vineis P, Herceg Z, Romieu I, Ferrari P

Clinical epigenetics Sep 2017

(DOI : 10.1186/s13148-018-0471-6)

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men.

Eriksson AL, Perry JR, Coviello AD, Delgado GE, Ferrucci L, Ikram MA, Kleber ME, Liu Y, Lorentzon M, Lunetta KL, Mellström D, Murabito JM, Murray A, Nethander M, Nielson CM, Prokopenko I, Raffel LJ, Rivadeneira F, Srikanth P, Stolk L, Teumer A, Uitterlinden AG, Vaidya D, Zmuda JM, März W, Orwoll ES, Vandenput L, Kiel DP, Ohlsson C

The Journal of clinical endocrinology and metabolism Sep 2017

(DOI : 10.1210/jc.2017-02060)

Digital technology to facilitate Proactive Assessment of Obesity Risk during Infancy (ProAsk): a feasibility study.

Redsell SA, Rose J, Weng S, Ablewhite J, Swift JA, Siriwardena AN, Nathan D, Wharrad HJ, Atkinson P, Watson V, McMaster F, Lakshman R, Glazebrook C

BMJ Open Sep 2017

(DOI : 10.1136/bmjopen-2017-017694)

Describing objectively measured physical activity levels, patterns, and correlates in a cross sectional sample of infants and toddlers from South Africa.

Prioreschi A, Brage S, Hesketh KD, Hnatiuk J, Westgate K, Micklesfield LK

The international journal of behavioral nutrition and physical activity Aug 2017

(DOI : 10.1186/s12966-017-0633-5)

Elucidating the genetic architecture of reproductive ageing in the Japanese population.

Horikoshi M, Day FR, Akiyama M, Hirata M, Kamatani Y, Matsuda K, Ishigaki K, Kanai M, Wright H, Toro CA, Ojeda SR, Lomniczi A, Kubo M, Ong KK, Perry JRB

Nature communications Aug 2017

(DOI : 10.1038/s41467-018-04398-z)

Associations of stunting in early childhood with cardiometabolic risk factors in adulthood.

De Lucia Rolfe E, de França GVA, Vianna CA, Gigante DP, Miranda JJ, Yudkin JS, Horta BL, Ong KK

PLoS ONE Aug 2017

(DOI : 10.1371/journal.pone.0192196)

Vomiting in pregnancy is associated with a higher risk of low birth weight: a cohort study.

Petry CJ, Ong KK, Beardsall K, Hughes IA, Acerini CL, Dunger DB

BMC pregnancy and childbirth Aug 2017

(DOI : 10.1186/s12884-018-1786-1)

Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort.

de Oliveira PD, Wehrmeister FC, Horta BL, Pérez-Padilla R, de França GVA, Gigante DP, Barros FC, Ong KK, De Lucia Rolfe E, Menezes AMB

BMC pulmonary medicine Aug 2017

(DOI : 10.1186/s12890-017-0510-7)

Baby-Led Weaning-Safe and Effective but Not Preventive of Obesity.

Lakshman R, Clifton EA, Ong KK

JAMA pediatrics Jul 2017

(DOI : 10.1001/jamapediatrics.2017.1766)

GWAS of epigenetic aging rates in blood reveals a critical role for TERT.

Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S

Nature communications Jul 2017

(DOI : 10.1038/s41467-017-02697-5)

Maternal Blood Pressure Rise During Pregnancy and Offspring Obesity Risk at 4 to 7 Years Old: The Jiaxing Birth Cohort.

Zheng JS, Liu H, Ong KK, Huang T, Guan Y, Yang B, Wang F, Li D

The Journal of clinical endocrinology and metabolism Jul 2017

(DOI : 10.1210/jc.2017-01500)

Replication and characterization of and genes on human behavior.

Boutwell B, Hinds D, 23andMe Research Team, Tielbeek J, Ong KK, Day FR, Perry JRB

Heliyon Jun 2017

(DOI : 10.1016/j.heliyon.2017.e00349)

Rapid weight gain during infancy and subsequent adiposity: a systematic review and meta-analysis of evidence.

Zheng M, Lamb KE, Grimes C, Laws R, Bolton K, Ong KK, Campbell K

Obesity reviews : an official journal of the International Association for the Study of Obesity Jun 2017

(DOI : 10.1111/obr.12632)

Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations.

Prins BP, Kuchenbaecker KB, Bao Y, Smart M, Zabaneh D, Fatemifar G, Luan J, Wareham NJ, Scott RA, Perry JRB, Langenberg C, Benzeval M, Kumari M, Zeggini E

Scientific reports May 2017

(DOI : 10.1038/s41598-017-10812-1)

Associations of lifestyle factors with serum dehydroepiandrosterone sulphate and insulin-like growth factor-1 concentration in prepubertal children.

Mäntyselkä A, Jääskeläinen J, Eloranta AM, Väistö J, Voutilainen R, Ong K, Brage S, Lakka TA, Lindi V

Clinical endocrinology May 2017

(DOI : 10.1111/cen.13511)

Associations between bacterial infections and blood pressure in pregnancy.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Pregnancy hypertension May 2017

(DOI : 10.1016/j.preghy.2017.09.004)

Mediation and modification of genetic susceptibility to obesity by eating behaviors.

de Lauzon-Guillain B, Clifton EA, Day FR, Clément K, Brage S, Forouhi NG, Griffin SJ, Koudou YA, Pelloux V, Wareham NJ, Charles MA, Heude B, Ong KK

The American Journal of Clinical Nutrition Mar 2017

(DOI : 10.3945/ajcn.117.157396)

Dissecting Causal Pathways Using Mendelian Randomization with Summarized Genetic Data: Application to Age at Menarche and Risk of Breast Cancer.

Burgess S, Thompson DJ, Rees JMB, Day FR, Perry JR, Ong KK

Genetics Mar 2017

(DOI : 10.1534/genetics.117.300191)

Evidence of Early-Stage Selection on EPAS1 and GPR126 Genes in Andean High Altitude Populations.

Eichstaedt CA, Pagani L, Antao T, Inchley CE, Cardona A, Mörseburg A, Clemente FJ, Sluckin TJ, Metspalu E, Mitt M, Mägi R, Hudjashov G, Metspalu M, Mormina M, Jacobs GS, Kivisild T

Scientific reports Mar 2017

(DOI : 10.1038/s41598-017-13382-4)

Identifying genetic variants that affect viability in large cohorts.

Mostafavi H, Berisa T, Day FR, Perry JRB, Przeworski M, Pickrell JK

PLoS biology Mar 2017

(DOI : 10.1371/journal.pbio.2002458)

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

Willems SM, Wright DJ, Day FR, Trajanoska K, Joshi PK, Morris JA, Matteini AM, Garton FC, Grarup N, Oskolkov N, Thalamuthu A, Mangino M, Liu J, Demirkan A, Lek M, Xu L, Wang G, Oldmeadow C, Gaulton KJ, Lotta LA, Miyamoto-Mikami E, Rivas MA, White T, Loh PR, Aadahl M, Amin N, Attia JR, Austin K, Benyamin B, Brage S, Cheng YC, Cięszczyk P, Derave W, Eriksson KF, Eynon N, Linneberg A, Lucia A, Massidda M, Mitchell BD, Miyachi M, Murakami H, Padmanabhan S, Pandey A, Papadimitriou I, Rajpal DK, Sale C, Schnurr TM, Sessa F, Shrine N, Tobin MD, Varley I, Wain LV, Wray NR, Lindgren CM, MacArthur DG, Waterworth DM, McCarthy MI, Pedersen O, Khaw KT, Kiel DP, GEFOS Any-Type of Fracture Consortium, Pitsiladis Y, Fuku N, Franks PW, North KN, van Duijn CM, Mather KA, Hansen T, Hansson O, Spector T, Murabito JM, Richards JB, Rivadeneira F, Langenberg C, Perry JRB, Wareham NJ, Scott RA

Nature communications Mar 2017

(DOI : 10.1038/ncomms16015)

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.

Teslovich TM, Stančáková A, Jackson AU, Perry JR, Huyghe JR, Stringham HM, Raulerson CK, Welch RP, Fuchsberger C, Locke AE, Chines PS, Narisu N, Gudnason V, Musani SK, Järvelin MR, Speliotes EK, Kuusisto J, Collins FS, Boehnke M, Laakso M, Mohlke KL

Human Molecular Genetics Feb 2017

(DOI : 10.1093/hmg/ddy067)

Early Pregnancy-Associated Plasma Protein A Concentrations Are Associated With Third Trimester Insulin Sensitivity.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Frystyk J, Dunger DB

The Journal of clinical endocrinology and metabolism Jan 2017

(DOI : 10.1210/jc.2017-00272)

Obesity-induced hypoadiponectinaemia: the opposite influences of central and peripheral fat compartments.

Borges MC, Oliveira IO, Freitas DF, Horta BL, Ong KK, Gigante DP, Barros AJD

International Journal of Epidemiology Jan 2017

(DOI : 10.1093/ije/dyx022)

Genomic ancestry and education level independently influence abdominal fat distributions in a Brazilian admixed population.

França GVA, De Lucia Rolfe E, Horta BL, Gigante DP, Yudkin JS, Ong KK, Victora CG

PLoS ONE Jan 2017

(DOI : 10.1371/journal.pone.0179085)

Determinants of Change in Physical Activity in Children 0-6 years of Age: A Systematic Review of Quantitative Literature.

Hesketh KR, O'Malley C, Paes VM, Moore H, Summerbell C, Ong KK, Lakshman R, van Sluijs EMF

Sports medicine (Auckland, N.Z.) Dec 2016

(DOI : 10.1007/s40279-016-0656-0)

Impact of Early Infant Growth, Duration of Breastfeeding and Maternal Factors on Total Body Fat Mass and Visceral Fat at 3 and 6 Months of Age.

Breij LM, Abrahamse-Berkeveld M, Acton D, De Lucia Rolfe E, Ong KK, Hokken-Koelega ACS

Annals of nutrition & metabolism Nov 2016

(DOI : 10.1159/000481539)

The translation of lipid profiles to nutritional biomarkers in the study of infant metabolism.

Acharjee A, Prentice P, Acerini C, Smith J, Hughes IA, Ong K, Griffin JL, Dunger D, Koulman A

Metabolomics : Official journal of the Metabolomic Society Nov 2016

(DOI : 10.1007/s11306-017-1166-2)

Systematic review indicates postnatal growth in term infants born small-for-gestational-age being associated with later neurocognitive and metabolic outcomes.

Castanys-Muñoz E, Kennedy K, Castañeda-Gutiérrez E, Forsyth S, Godfrey KM, Koletzko B, Ozanne SE, Rueda R, Schoemaker M, van der Beek EM, van Buuren S, Ong KK

Acta paediatrica (Oslo, Norway : 1992) Nov 2016

(DOI : 10.1111/apa.13868)

Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation.

Mullin BH, Zhao JH, Brown SJ, Perry JRB, Luan J, Zheng HF, Langenberg C, Dudbridge F, Scott R, Wareham NJ, Spector TD, Richards JB, Walsh JP, Wilson SG

Human Molecular Genetics Oct 2016

(DOI : 10.1093/hmg/ddx174)

Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.

Lotta LA, Sharp SJ, Burgess S, Perry JR, Stewart ID, Willems S, Luan J, Ardanaz E, Arriola L, Balkau B, Boeing H, Deloukas P, Forouhi NG, Franks PW, Grioni S, Kaaks R, Key TJ, Navarro C, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Riboli E, Rolandsson O, Sacerdote C, Slimani N, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, van der Schouw YT, McCarthy MI, Barroso I, O'Rahilly S, Savage DB, Sattar N, Langenberg C, Scott RA, Wareham NJ

JAMA Oct 2016

(DOI : 10.1001/jama.2016.14568)