MRC Epidemiology Unit

Search MRC Epidemiology Unit publications by journal, author, programme, study, publication year and keyword from 2007 to 2022.

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There are 3992 publications in the database

Modifiable lifestyle behaviors and functional health in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study

Bingham SA, Harvey I, Khaw KT, Luben RN, Myint PK, Smith RD, Surtees PG, Wainwright NW, Wareham NJ, and Welch AA

Preventive Medicine . Feb 2007

(DOI : 10.1016/j.ypmed.2006.09.007)

Genome-wide association study identifies novel breast cancer susceptibility loci.

Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R, Wareham NJ, Ahmed S, Healey CS, Bowman R, Meyer KB, Haiman CA, Kolonel LK, Henderson BE, Le Marchand L, Brennan P, Sangrajrang S, Gaborieau V, Odefrey F, Shen CY, Wu PE, Wang HC, Eccles D, Evans DG, Peto J, Fletcher O, Johnson N, Seal S, Stratton MR, Rahman N, Chenevix-Trench G, Bojesen SE, Nordestgaard BG, Axelsson CK, García-Closas M, Brinton L, Chanock S, Lissowska J, Peplonska B, Nevanlinna H, Fagerholm R, Eerola H, Kang D, Yoo KY, Noh DY, Ahn SH, Hunter DJ, Hankinson SE, Cox DG, Hall P, Wedren S, Liu J, Low YL, Bogdanova N, Schürmann P, Dörk T, Tollenaar RA, Jacobi CE, Devilee P, Klijn JG, Sigurdson AJ, Doody MM, Alexander BH, Zhang J, Cox A, Brock IW, MacPherson G, Reed MW, Couch FJ, Goode EL, Olson JE, Meijers-Heijboer H, van den Ouweland A, Uitterlinden A, Rivadeneira F, Milne RL, Ribas G, González-Neira A, Benitez J, Hopper JL, McCredie M, Southey M, Giles GG, Schroen C, Justenhoven C, Brauch H, Hamann U, Ko YD, Spurdle AB, Beesley J, Chen X, Mannermaa A, Kosma VM, Kataja V, Hartikainen J, Day NE, Cox DR, and Ponder BA

Nature. Feb 2007

(DOI : 10.1038/nature05887)

Differential effects of fatness, fitness and physical activity energy expenditure on whole-body, liver and fat insulin sensitivity.

Holt HB, Wild SH, Wareham NJ, Ekelund U, Umpleby M, Shojaee-Moradie F, Holt RI, Phillips DI, and Byrne CD

Diabetologia. Feb 2007

(DOI : 10.1007/s00125-007-0705-1)

Serum levels of C-peptide, IGFBP-1 and IGFBP-2 and endometrial cancer risk; results from the European prospective investigation into cancer and nutrition.

Cust AE, Allen NE, Rinaldi S, Dossus L, Friedenreich C, Olsen A, Tjønneland A, Overvad K, Clavel-Chapelon F, Boutron-Ruault MC, Linseisen J, Chang-Claude J, Boeing H, Schulz M, Benetou V, Trichopoulou A, Trichopoulos D, Palli D, Berrino F, Tumino R, Mattiello A, Vineis P, Quirós JR, Agudo A, Sánchez MJ, Larrañaga N, Navarro C, Ardanaz E, Bueno-de-Mesquita HB, Peeters PH, van Gils CH, Bingham S, Khaw KT, Key T, Slimani N, Riboli E, and Kaaks R

International journal of cancer. Feb 2007

(DOI : 10.1002/ijc.22578)

Common variants in WFS1 confer risk of type 2 diabetes.

Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, Daly A, Lango H, Frayling TM, Neumann RJ, Sherva R, Blech I, Pharoah PD, Palmer CN, Kimber C, Tavendale R, Morris AD, McCarthy MI, Walker M, Hitman G, Glaser B, Permutt MA, Hattersley AT, Wareham NJ, and Barroso I

Nature genetics. Feb 2007

(DOI : 10.1038/ng2067)

Gene-lifestyle interaction on risk of type 2 diabetes

Wareham NJ, Franks PW, Mesa JL, and Harding AH

Nutrition, Metabolism & Cardiovascular Diseases. Feb 2007

(DOI : 10.1016/j.numecd.2006.04.001)

Effects of physical activity on evolution of proximal femur structure in a younger elderly population

Wareham NJ, Khaw KT, Kaptoge S, Jakes RW, Dalzell N, Loveridge N, Beck TJ, and Reeve J

Bone. Feb 2007

(DOI : 10.1016/j.bone.2006.09.021)

Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies

Wareham NJ, Bingham SA, Boekholdt SM, Khaw KT, Sarwar N, Danesh J, Eiriksdottir G, Sigurdsson G, and Gudnason V

Circulation. Jan 2007

(DOI : 10.1161/CIRCULATIONAHA.106.637793)

Incidence of Type 2 diabetes in England and its association with baseline impaired fasting glucose: the Ely study 1990-2000.

Forouhi NG, Luan J, Hennings S, and Wareham NJ

Diabetic medicine : a journal of the British Diabetic Association. Jan 2007

(DOI : 10.1111/j.1464-5491.2007.02068.x)

Physical activity and metabolic risk in individuals with a family history of type 2 diabetes.

Ekelund U, Griffin SJ, and Wareham NJ

Diabetes care. Jan 2007

(DOI : 10.2337/dc06-1883)

Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.

Baynes C, Healey CS, Pooley KA, Scollen S, Luben RN, Thompson DJ, Pharoah PD, Easton DF, Ponder BA, Dunning AM, and SEARCH breast cancer study

Breast cancer research : BCR. Jan 2007

(DOI : 10.1186/bcr1669)

Physical activity energy expenditure may mediate the relationship between plasma leptin levels and worsening insulin resistance independently of adiposity.

Franks PW, Loos RJ, Brage S, O'Rahilly S, Wareham NJ, and Ekelund U

Journal of applied physiology (Bethesda, Md. : 1985). Jan 2007

(DOI : 10.1152/japplphysiol.01022.2006)

Socioeconomic position and the risk of gastric and oesophageal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST).

Nagel G, Linseisen J, Boshuizen HC, Pera G, Del Giudice G, Westert GP, Bueno-de-Mesquita HB, Allen NE, Key TJ, Numans ME, Peeters PH, Sieri S, Simán H, Berglund G, Hallmans G, Stenling R, Martínez C, Arriola L, Barricarte A, Chirlaque MD, Quirós JR, Vineis P, Masala G, Palli D, Panico S, Tumino R, Bingham S, Boeing H, Bergmann MM, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Olsen A, Tjonneland A, Trichopoulou A, Bamia C, Soukara S, Sabourin JC, Carneiro F, Slimani N, Jenab M, Norat T, Riboli E, and González CA

International Journal of Epidemiology. Jan 2007

(DOI : 10.1093/ije/dyl275)

Comment on "A common genetic variant is associated with adult and childhood obesity".

Loos RJ, Barroso I, O'Rahilly S, and Wareham NJ

Science (New York, N.Y.). Jan 2007

(DOI : 10.1126/science.1130012)

Endogenous androgens and risk of epithelial ovarian cancer: results from the European Prospective Investigation into Cancer and Nutrition (EPIC).

Rinaldi S, Dossus L, Lukanova A, Peeters PH, Allen NE, Key T, Bingham S, Khaw KT, Trichopoulos D, Trichopoulou A, Oikonomou E, Pera G, Larrañaga N, Martinez-Garcia C, Ardanaz E, Quirós JR, Tormo MJ, Tjønneland A, Olsen A, Overvad K, Chang-Claude J, Linseisen J, Schulz M, Boeing H, van Gils CH, Bueno-de-Mesquita BH, Pala V, Palli D, Panico S, Tumino R, Vineis P, Clavel-Chapelon F, Mesrine S, Boutron-Ruault MC, Lundin E, Agren A, Berglund G, Manjer J, Kumle M, Lund E, Slimani N, Saracci R, Riboli E, and Kaaks R

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Jan 2007

(DOI : 10.1158/1055-9965.EPI-06-0755)

Fruit and vegetable consumption and self-reported functional health in men and women in the European Prospective Investigation into Cancer-Norfolk (EPIC-Norfolk): a population-based cross-sectional study.

Myint PK, Welch AA, Bingham SA, Surtees PG, Wainwright NW, Luben RN, Wareham NJ, Smith RD, Harvey IM, Day NE, and Khaw KT

Public Health Nutrition. Jan 2007

(DOI : 10.1017/S1368980007222608)

Early elective insulin therapy can reduce hyperglycemia and increase insulin-like growth factor-I levels in very low birth weight infants.

Beardsall K, Ogilvy-Stuart AL, Frystyk J, Chen JW, Thompson M, Ahluwalia J, Ong KK, and Dunger DB

The Journal of pediatrics. Jan 2007

(DOI : 10.1016/j.jpeds.2007.04.068)

Glycated hemoglobin and risk of stroke in people without known diabetes in the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study: a threshold relationship?

Myint PK, Sinha S, Wareham NJ, Bingham SA, Luben RN, Welch AA, and Khaw KT

Stroke. Jan 2007

(DOI : 10.1161/01.STR.0000254549.75763.5f)

Plasma phytoestrogens and subsequent breast cancer risk.

Verheus M, van Gils CH, Keinan-Boker L, Grace PB, Bingham SA, and Peeters PH

Journal of clinical oncology : official journal of the American Society of Clinical Oncology. Jan 2007

(DOI : 10.1200/JCO.2006.06.0244)

The emergence of networks in human genome epidemiology: challenges and opportunities.

Seminara D, Khoury MJ, O'Brien TR, Manolio T, Gwinn ML, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam AP, Danesh J, Davey Smith G, Dolan S, Duncan R, Gruis NA, Hashibe M, Hunter D, Järvelin MR, Malmer B, Maraganore DM, Newton-Bishop JA, Riboli E, Salanti G, Taioli E, Timpson N, Uitterlinden AG, Vineis P, Wareham NJ, Winn DM, Zimmern R, and Ioannidis JP

Epidemiology (Cambridge, Mass.). Dec 2006

(DOI : 10.1097/01.ede.0000249540.17855.b7)

Physical activity and breast cancer risk: the European Prospective Investigation into Cancer and Nutrition.

Lahmann PH, Friedenreich C, Schuit AJ, Salvini S, Allen NE, Key TJ, Khaw KT, Bingham S, Peeters PH, Monninkhof E, Bueno-de-Mesquita HB, Wirfält E, Manjer J, Gonzáles CA, Ardanaz E, Amiano P, Quirós JR, Navarro C, Martínez C, Berrino F, Palli D, Tumino R, Panico S, Vineis P, Trichopoulou A, Bamia C, Trichopoulos D, Boeing H, Schulz M, Linseisen J, Chang-Claude J, Chapelon FC, Fournier A, Boutron-Ruault MC, Tjønneland A, Føns Johnson N, Overvad K, Kaaks R, and Riboli E

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Dec 2006

(DOI : 10.1158/1055-9965.EPI-06-0582)

Diet-induced endogenous formation of nitroso compounds in the GI tract.

Kuhnle GG, Story GW, Reda T, Mani AR, Moore KP, Lunn JC, and Bingham SA

Free radical biology & medicine. Dec 2006

(DOI : 10.1016/j.freeradbiomed.2007.03.011)

Lack of association between common polymorphisms in the 17beta-hydroxysteroid dehydrogenase type V gene (HSD17B5) and precocious pubarche.

Petry CJ, Ong KK, Wingate DL, de Zegher F, Ibáñez L, and Dunger DB

The Journal of steroid biochemistry and molecular biology. Dec 2006

(DOI : 10.1016/j.jsbmb.2007.01.004)

Physical activity and risk of colon and rectal cancers: the European prospective investigation into cancer and nutrition.

Friedenreich C, Norat T, Steindorf K, Boutron-Ruault MC, Pischon T, Mazuir M, Clavel-Chapelon F, Linseisen J, Boeing H, Bergman M, Johnsen NF, Tjønneland A, Overvad K, Mendez M, Quirós JR, Martínez C, Dorronsoro M, Navarro C, Gurrea AB, Bingham S, Khaw KT, Allen N, Key T, Trichopoulou A, Trichopoulos D, Orfanou N, Krogh V, Palli D, Tumino R, Panico S, Vineis P, Bueno-de-Mesquita HB, Peeters PH, Monninkhof E, Berglund G, Manjer J, Ferrari P, Slimani N, Kaaks R, and Riboli E

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Dec 2006

(DOI : 10.1158/1055-9965.EPI-06-0595)

TV viewing and physical activity are independently associated with metabolic risk in children: the European Youth Heart Study

Brage S, Andersen LB, anderssen-sa Anderssen SA, Ekelund U, Froberg K, Riddoch C, Sardinha LB, and Harro M

PLoS Medicine. Dec 2006

(DOI : 10.1371/journal.pmed.0030488)

Comparison of different definitions of the metabolic syndrome in relation to cardiovascular mortality in European men and women

and DECODE Study Group

Diabetologia. Dec 2006

(DOI : 10.1007/s00125-006-0438-6)

Physical activity, C-reactive protein levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study

Wareham NJ, Bingham SA, Boekholdt SM, Day NE, Khaw KT, Luben RN, Peters RJ, and Sandhu MS

European Journal of Preventive Cardiology. Dec 2006

(DOI : 10.1097/01.hjr.0000209811.97948.07)

Glycated hemoglobin as a marker of cardiovascular risk

Wareham NJ, and Khaw KT

Current opinion in lipidology. Dec 2006

(DOI : 10.1097/MOL.0b013e3280106b95)

Dietary fish intake and plasma phospholipid n-3 polyunsaturated fatty acid concentrations in men and women in the European Prospective Investigation into Cancer-Norfolk United Kingdom cohort

Wareham NJ, Bingham SA, Khaw KT, Ive J, Friesen MD, Riboli E, and Welch AA

The American Journal of Clinical Nutrition. Dec 2006

(DOI : 10.1093/ajcn/84.6.1330)

CagA+ Helicobacter pylori infection and gastric cancer risk in the EPIC-EURGAST study.

Palli D, Masala G, Del Giudice G, Plebani M, Basso D, Berti D, Numans ME, E Numans M, Ceroti M, Peeters PH, Bueno de Mesquita HB, Büchner FL, Clavel-Chapelon F, Boutron-Ruault MC, Krogh V, Saieva C, Vineis P, Panico S, Tumino R, Nyrén O, Simán H, Berglund G, Hallmans G, Sánchez MJ, Larrañaga N, Barricarte A, Navarro C, Quirós JR, Key T, Allen N, Bingham S, Khaw KT, Boeing H, Weikert C, Linseisen J, Nagel G, Overvad K, Thomsen RW, Tjonneland A, Olsen A, Trichoupoulou A, Trichopoulos D, Arvaniti A, Pera G, Kaaks R, Jenab M, Ferrari P, Nesi G, Carneiro F, Riboli E, and González CA

International journal of cancer. Nov 2006

(DOI : 10.1002/ijc.22435)

Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study.

Meuwese MC, Stroes ES, Hazen SL, van Miert JN, Kuivenhoven JA, Schaub RG, Wareham NJ, Luben R, Kastelein JJ, Khaw KT, and Boekholdt SM

Journal of the American College of Cardiology. Nov 2006

(DOI : 10.1016/j.jacc.2007.03.033)

Elevated serum ferritin levels predict new-onset type 2 diabetes: results from the EPIC-Norfolk prospective study.

Forouhi NG, Harding AH, Allison M, Sandhu MS, Welch A, Luben R, Bingham S, Khaw KT, and Wareham NJ

Diabetologia. Nov 2006

(DOI : 10.1007/s00125-007-0604-5)

EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries.

Danesh J, Saracci R, Berglund G, Feskens E, Overvad K, Panico S, Thompson S, Fournier A, Clavel-Chapelon F, Canonico M, Kaaks R, Linseisen J, Boeing H, Pischon T, Weikert C, Olsen A, Tjønneland A, Johnsen SP, Jensen MK, Quirós JR, Svatetz CA, Pérez MJ, Larrañaga N, Sanchez CN, Iribas CM, Bingham S, Khaw KT, Wareham NJ, Key T, Roddam A, Trichopoulou A, Benetou V, Trichopoulos D, Masala G, Sieri S, Tumino R, Sacerdote C, Mattiello A, Verschuren WM, Bueno-de-Mesquita HB, Grobbee DE, van der Schouw YT, Melander O, Hallmans G, Wennberg P, Lund E, Kumle M, Skeie G, Ferrari P, Slimani N, Norat T, and Riboli E

European Journal of Epidemiology. Nov 2006

(DOI : 10.1007/s10654-006-9096-8)

Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes

Wareham NJ, Harding AH, Luan J, O'Rahilly S, and Barroso I

Diabetologia. Nov 2006

(DOI : 10.1007/s00125-006-0430-1)

Plasma levels of plant sterols and the risk of coronary artery disease: the prospective EPIC-Norfolk Population Study

Wareham NJ, Boekholdt SM, Kastelein JJ, Khaw KT, Luben RN, Vissers PAJ, Pinedo S, Von Bergmann K, Elharchaoui K, and Lütjohann D

Journal of lipid research. Oct 2006

(DOI : 10.1194/jlr.M600371-JLR200)

PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge.

Franks PW, Ekelund U, Brage S, Luan J, Schafer AJ, O'Rahilly S, Barroso I, and Wareham NJ

Diabetologia. Oct 2006

(DOI : 10.1007/s00125-006-0580-1)

Fruit and vegetable consumption and lymphoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).

Rohrmann S, Becker N, Linseisen J, Nieters A, Rüdiger T, Raaschou-Nielsen O, Tjønneland A, Johnsen HE, Overvad K, Kaaks R, Bergmann MM, Boeing H, Benetou V, Psaltopoulou T, Trichopoulou A, Masala G, Mattiello A, Krogh V, Tumino R, van Gils CH, Peeters PH, Bueno-de-Mesquita HB, Ros MM, Lund E, Ardanaz E, Chirlaque MD, Jakszyn P, Larrañaga N, Losada A, Martinez-Garcia C, Agren A, Hallmans G, Berglund G, Manjer J, Allen NE, Key TJ, Bingham S, Khaw KT, Slimani N, Ferrari P, Boffetta P, Norat T, Vineis P, and Riboli E

Cancer causes & control : CCC. Oct 2006

(DOI : 10.1007/s10552-007-0125-z)

Plasma adiponectin levels and endometrial cancer risk in pre- and postmenopausal women.

Cust AE, Kaaks R, Friedenreich C, Bonnet F, Laville M, Lukanova A, Rinaldi S, Dossus L, Slimani N, Lundin E, Tjønneland A, Olsen A, Overvad K, Clavel-Chapelon F, Mesrine S, Joulin V, Linseisen J, Rohrmann S, Pischon T, Boeing H, Trichopoulos D, Trichopoulou A, Benetou V, Palli D, Berrino F, Tumino R, Sacerdote C, Mattiello A, Quirós JR, Mendez MA, Sánchez MJ, Larrañaga N, Tormo MJ, Ardanaz E, Bueno-de-Mesquita HB, Peeters PH, van Gils CH, Khaw KT, Bingham S, Allen N, Key T, Jenab M, and Riboli E

The Journal of clinical endocrinology and metabolism. Oct 2006

(DOI : 10.1210/jc.2006-1371)

Association of weight gain in infancy and early childhood with metabolic risk in young adults.

Ekelund U, Ong KK, Linné Y, Neovius M, Brage S, Dunger DB, Wareham NJ, and Rössner S

The Journal of clinical endocrinology and metabolism. Oct 2006

(DOI : 10.1210/jc.2006-1071)

Earlier mother's age at menarche predicts rapid infancy growth and childhood obesity.

Ong KK, Northstone K, Wells JC, Rubin C, Ness AR, Golding J, and Dunger DB

PLoS Medicine. Oct 2006

(DOI : 10.1371/journal.pmed.0040132)

PGC-1alpha gene and physical activity in type 2 diabetes mellitus

Franks PW, and Loos R

Exercise and sport sciences reviews. Oct 2006

(DOI : 10.1249/01.jes.0000240021.92254.23)

Anthropometric factors and risk of endometrial cancer: the European prospective investigation into cancer and nutrition.

Friedenreich C, Cust A, Lahmann PH, Steindorf K, Boutron-Ruault MC, Clavel-Chapelon F, Mesrine S, Linseisen J, Rohrmann S, Boeing H, Pischon T, Tjønneland A, Halkjaer J, Overvad K, Mendez M, Redondo ML, Garcia CM, Larrañaga N, Tormo MJ, Gurrea AB, Bingham S, Khaw KT, Allen N, Key T, Trichopoulou A, Vasilopoulou E, Trichopoulos D, Pala V, Palli D, Tumino R, Mattiello A, Vineis P, Bueno-de-Mesquita HB, Peeters PH, Berglund G, Manjer J, Lundin E, Lukanova A, Slimani N, Jenab M, Kaaks R, and Riboli E

Cancer causes & control : CCC. Oct 2006

(DOI : 10.1007/s10552-006-0113-8)

Habitual fish consumption and risk of incident stroke: the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.

Myint PK, Welch AA, Bingham SA, Luben RN, Wareham NJ, Day NE, and Khaw KT

Public Health Nutrition. Oct 2006

(DOI : 10.1017/phn2006942)

PARL Leu262Val is not associated with fasting insulin levels in UK populations

Wareham NJ, Barroso I, Cooper C, Day NE, Luan J, O'Rahilly S, Sandhu MS, Fawcett KA, and Syddall H

Diabetologia. Sep 2006

(DOI : 10.1007/s00125-006-0443-9)

Implications of gene-environment interaction in studies of gene variants in breast cancer: an example of dietary isoflavones and the D356N polymorphism in the sex hormone-binding globulin gene.

Low YL, Dunning AM, Dowsett M, Luben RN, Khaw KT, Wareham NJ, and Bingham SA

Cancer research. Sep 2006

(DOI : 10.1158/0008-5472.CAN-06-2432)

Do known risk factors explain the higher coronary heart disease mortality in South Asian compared with European men? Prospective follow-up of the Southall and Brent studies, UK

Forouhi NG, Chaturvedi N, McKeigue PM, Sattar N, and Tillin T

Diabetologia. Sep 2006

(DOI : 10.1007/s00125-006-0393-2)

Compensatory mammary growth following protein restriction during pregnancy and lactation increases early-onset mammary tumor incidence in rats.

Fernandez-Twinn DS, Ekizoglou S, Gusterson BA, Luan J, and Ozanne SE

Carcinogenesis. Sep 2006

(DOI : 10.1093/carcin/bgl166)

Alcohol intake and breast cancer risk: the European Prospective Investigation into Cancer and Nutrition (EPIC).

Tjønneland A, Christensen J, Olsen A, Stripp C, Thomsen BL, Overvad K, Peeters PH, van Gils CH, Bueno-de-Mesquita HB, Ocké MC, Thiebaut A, Fournier A, Clavel-Chapelon F, Berrino F, Palli D, Tumino R, Panico S, Vineis P, Agudo A, Ardanaz E, Martinez-Garcia C, Amiano P, Navarro C, Quirós JR, Key TJ, Reeves G, Khaw KT, Bingham S, Trichopoulou A, Trichopoulos D, Naska A, Nagel G, Chang-Claude J, Boeing H, Lahmann PH, Manjer J, Wirfält E, Hallmans G, Johansson I, Lund E, Skeie G, Hjartåker A, Ferrari P, Slimani N, Kaaks R, and Riboli E

Cancer causes & control : CCC. Sep 2006

(DOI : 10.1007/s10552-006-0112-9)

Is the association between physical activity and body mass index obesity dependent?

Ekelund U, and Hemmingsson E

International Journal of Obesity (London). Sep 2006

(DOI : 10.1038/sj.ijo.0803458)

Combined work and leisure physical activity and risk of stroke in men and women in the European prospective investigation into Cancer-Norfolk Prospective Population Study.

Myint PK, Luben RN, Wareham NJ, Welch AA, Bingham SA, Day NE, and Khaw KT

Neuroepidemiology. Sep 2006

(DOI : 10.1159/000095551)

Intakes and sources of soya foods and isoflavones in a UK population cohort study (EPIC-Norfolk).

Mulligan AA, Welch AA, McTaggart AA, Bhaniani A, and Bingham SA

European Journal of Clinical Nutrition. Sep 2006

(DOI : 10.1038/sj.ejcn.1602509)

A common variant of the p16(INK4a) genetic region is associated with physical function in older people.

Melzer D, Frayling TM, Murray A, Hurst AJ, Harries LW, Song H, Khaw K, Luben R, Surtees PG, Bandinelli SS, Corsi AM, Ferrucci L, Guralnik JM, Wallace RB, Hattersley AT, and Pharoah PD

Mechanisms of ageing and development. Aug 2006

(DOI : 10.1016/j.mad.2007.03.005)

Tissue factor serum levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.

Keller TT, Choi D, Nagel C, Te Velthuis H, Gerdes VE, Wareham NJ, Bingham SA, Luben R, Hack CE, Reitsma PH, Levi M, Khaw KT, and Boekholdt SM

Journal of thrombosis and haemostasis : JTH. Aug 2006

(DOI : 10.1111/j.1538-7836.2006.02190.x)

The role of diabetes and components of the metabolic syndrome in stroke and coronary heart disease mortality in U.K. white and African-Caribbean populations.

Tillin T, Forouhi NG, McKeigue PM, and Chaturvedi N

Diabetes care. Aug 2006

(DOI : 10.2337/dc06-0779)

Commentary: fat and breast cancer: time to re-evaluate both methods and results?

Bingham SA, and Day N

International Journal of Epidemiology. Aug 2006

(DOI : 10.1093/ije/dyl142)

Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: the EPIC-Norfolk prospective population study.

Boekholdt SM, Meuwese MC, Day NE, Luben R, Welch A, Wareham NJ, and Khaw KT

The British journal of nutrition. Aug 2006

(DOI : S0007114506002583)

Studies of the SIM1 gene in relation to human obesity and obesity-related traits.

Hung CC, Luan J, Sims M, Keogh JM, Hall C, Wareham NJ, O'Rahilly S, and Farooqi IS

International Journal of Obesity. Aug 2006

(DOI : 10.1038/sj.ijo.0803443)

Routinely collected general practice data aids identification of people with hyperglycaemia and metabolic syndrome.

Heldgaard PE, and Griffin SJ

Diabetic medicine : a journal of the British Diabetic Association. Aug 2006

(DOI : 10.1111/j.1464-5491.2006.01929.x)

Longitudinal changes in insulin-like growth factor-I, insulin sensitivity, and secretion from birth to age three years in small-for-gestational-age children.

Iñiguez G, Ong K, Bazaes R, Avila A, Salazar T, Dunger D, and Mericq V

The Journal of clinical endocrinology and metabolism. Aug 2006

(DOI : 10.1210/jc.2006-0844)

Association of alpha-synuclein gene haplotypes with Parkinson's disease.

Parsian AJ, Racette BA, Zhao JH, Sinha R, Patra B, Perlmutter JS, and Parsian A

Parkinsonism & related disorders. Aug 2006

(DOI : 10.1016/j.parkreldis.2006.12.006)

Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women.

Keller TT, van Leuven SI, Meuwese MC, Wareham NJ, Luben R, Stroes ES, Hack CE, Levi M, Khaw KT, and Boekholdt SM

Arteriosclerosis, thrombosis, and vascular biology. Aug 2006

(DOI : 10.1161/01.ATV.0000240517.69201.77)

Diet, serum insulin-like growth factor-I and IGF-binding protein-3 in European women.

Norat T, Dossus L, Rinaldi S, Overvad K, Grønbaek H, Tjønneland A, Olsen A, Clavel-Chapelon F, Boutron-Ruault MC, Boeing H, Lahmann PH, Linseisen J, Nagel G, Trichopoulou A, Trichopoulos D, Kalapothaki V, Sieri S, Palli D, Panico S, Tumino R, Sacerdote C, Bueno-de-Mesquita HB, Peeters PH, van Gils CH, Agudo A, Amiano P, Ardanoz E, Martínez C, Quirós R, Tormo MJ, Bingham S, Key TJ, Allen NE, Ferrari P, Slimani N, Riboli E, and Kaaks R

European Journal of Clinical Nutrition. Aug 2006

(DOI : 10.1038/sj.ejcn.1602494)

Physical activity and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition Cohort.

Steindorf K, Friedenreich C, Linseisen J, Rohrmann S, Rundle A, Veglia F, Vineis P, Johnsen NF, Tjønneland A, Overvad K, Raaschou-Nielsen O, Clavel-Chapelon F, Boutron-Ruault MC, Schulz M, Boeing H, Trichopoulou A, Kalapothaki V, Koliva M, Krogh V, Palli D, Tumino R, Panico S, Monninkhof E, Peeters PH, Boshuizen HC, Bueno-de-Mesquita HB, Chirlaque MD, Agudo A, Larrañaga N, Quirós JR, Martínez C, Barricarte A, Janzon L, Berglund G, Bingham S, Khaw KT, Key TJ, Norat T, Jenab M, Cust A, and Riboli E

International journal of cancer. Aug 2006

(DOI : 10.1002/ijc.22125)

Tobacco smoke and bladder cancer--in the European Prospective Investigation into Cancer and Nutrition.

Bjerregaard BK, Raaschou-Nielsen O, Sørensen M, Frederiksen K, Christensen J, Tjønneland A, Overvad K, Chapelon FC, Nagel G, Chang-Claude J, Bergmann MM, Boeing H, Trichopoulos D, Trichopoulou A, Oikonomou E, Berrino F, Palli D, Tumino R, Vineis P, Panico S, Peeters PH, Bueno-de-Mesquita HB, Kiemeney L, Gram IT, Braaten T, Lund E, González CA, Berglund G, Allen N, Roddam A, Bingham S, and Riboli E

International journal of cancer. Aug 2006

(DOI : 10.1002/ijc.22169)

Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study.

El Harchaoui K, van der Steeg WA, Stroes ES, Kuivenhoven JA, Otvos JD, Wareham NJ, Hutten BA, Kastelein JJ, Khaw KT, and Boekholdt SM

Journal of the American College of Cardiology. Aug 2006

(DOI : 10.1016/j.jacc.2006.09.043)

Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions.

Ong KK, and Loos RJ

Acta paediatrica (Oslo, Norway : 1992). Aug 2006

(DOI : 10.1080/08035250600719754)

Fibrinogen plasma levels modify the association between the factor XIII Val34Leu variant and risk of coronary artery disease: the EPIC-Norfolk prospective population study.

Boekholdt SM, Sandhu MS, Wareham NJ, Luben R, Reitsma PH, and Khaw KT

Journal of thrombosis and haemostasis : JTH. Aug 2006

(DOI : 10.1111/j.1538-7836.2006.02154.x)

Twin birth weight standards.

Gielen M, Lindsey PJ, Derom C, Loos RJ, Derom R, Nijhuis JG, and Vlietinck R

Neonatology. Aug 2006

(DOI : 10.1159/000102055)

Dietary intake of folate equivalents and risk of myocardial infarction in the European Prospective Investigation into Cancer and Nutrition (EPIC)--Potsdam study.

Drogan D, Klipstein-Grobusch K, Dierkes J, Weikert C, and Boeing H

Public Health Nutrition. Jul 2006

(DOI : 10.1079/phn2005863)

Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.

Collins SC, Luan J, Thompson AJ, Daly A, Semple RK, O'Rahilly S, Wareham NJ, and Barroso I

Diabetologia. Jul 2006

(DOI : 10.1007/s00125-006-0534-7)

Physical activity and clustered cardiovascular risk in children: a cross-sectional study (The European Youth Heart Study).

Andersen LB, Harro M, Sardinha LB, Froberg K, Ekelund U, Brage S, and Anderssen SA

Lancet (London, England). Jul 2006

(DOI : 10.1016/S0140-6736(06)69075-2)

Obesity indices and self-reported functional health in men and women in the EPIC-Norfolk.

Myint PK, Welch AA, Luben RN, Wainwright NW, Surtees PG, Bingham SA, Wareham NJ, Smith RD, Harvey IM, and Khaw KT

Obesity (Silver Spring, Md.). Jul 2006

(DOI : 10.1038/oby.2006.102)

Genetic variants and common diseases--better late than never.

O'Rahilly S, and Wareham NJ

The New England journal of medicine. Jul 2006

(DOI : 10.1056/NEJMe068140)

Temporal trends in physical activity in England: the Health Survey for England 1991 to 2004.

Stamatakis E, Ekelund U, and Wareham NJ

Preventive Medicine . Jul 2006

(DOI : 10.1016/j.ypmed.2006.12.014)

TP53 and KRAS2 mutations in plasma DNA of healthy subjects and subsequent cancer occurrence: a prospective study.

Gormally E, Vineis P, Matullo G, Veglia F, Caboux E, Le Roux E, Peluso M, Garte S, Guarrera S, Munnia A, Airoldi L, Autrup H, Malaveille C, Dunning A, Overvad K, Tjønneland A, Lund E, Clavel-Chapelon F, Boeing H, Trichopoulou A, Palli D, Krogh V, Tumino R, Panico S, Bueno-de-Mesquita HB, Peeters PH, Pera G, Martínez C, Dorronsoro M, Barricarte A, Navarro C, Quirós JR, Hallmans G, Day NE, Key TJ, Saracci R, Kaaks R, Riboli E, and Hainaut P

Cancer research. Jul 2006

(DOI : 10.1158/0008-5472.CAN-05-4556)

Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study.

Vaessen SF, Schaap FG, Kuivenhoven JA, Groen AK, Hutten BA, Boekholdt SM, Hattori H, Sandhu MS, Bingham SA, Luben R, Palmen JA, Wareham NJ, Humphries SE, Kastelein JJ, Talmud PJ, and Khaw KT

Journal of lipid research. Jun 2006

(DOI : 10.1194/jlr.M600233-JLR200)

Lessons from large population studies on timing and tempo of puberty (secular trends and relation to body size): the European trend.

Ong KK, Ahmed ML, and Dunger DB

Molecular and cellular endocrinology. Jun 2006

(DOI : 10.1016/j.mce.2006.04.018)

A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3).

Cox DG, Blanché H, Pearce CL, Calle EE, Colditz GA, Pike MC, Albanes D, Allen NE, Amiano P, Berglund G, Boeing H, Buring J, Burtt N, Canzian F, Chanock S, Clavel-Chapelon F, Feigelson HS, Freedman M, Haiman CA, Hankinson SE, Henderson BE, Hoover R, Hunter DJ, Kaaks R, Kolonel L, Kraft P, Lemarchand L, Lund E, Palli D, Peeters PH, Riboli E, Stram DO, Thun M, Tjonneland A, Trichopoulos D, Yeager M, and Breast and Prostate Cancer Cohort Consortium

Breast cancer research : BCR. Jun 2006

(DOI : 10.1186/bcr1602)

Dietary fat intake predicts 1-year change in body fat in adolescent girls with type 1 diabetes.

Särnblad S, Ekelund U, and Åman J

Diabetes care. May 2006

(DOI : 10.2337/dc05-2318)

Work and leisure time physical activity assessed using a simple, pragmatic, validated questionnaire and incident cardiovascular disease and all-cause mortality in men and women: The European Prospective Investigation into Cancer in Norfolk prospective population study.

Khaw KT, Jakes R, Bingham S, Welch A, Luben R, Day N, and Wareham NJ

International Journal of Epidemiology. May 2006

(DOI : 10.1093/ije/dyl079)

Elevated plasma adiponectin in humans with genetically defective insulin receptors.

Semple RK, Soos MA, Luan J, Mitchell CS, Wilson JC, Gurnell M, Cochran EK, Gorden P, Chatterjee VK, Wareham NJ, and O'Rahilly S

The Journal of clinical endocrinology and metabolism. May 2006

(DOI : 10.1210/jc.2006-0166)

Anthropometry, physical activity, and the risk of pancreatic cancer in the European prospective investigation into cancer and nutrition.

Berrington de González A, Spencer EA, Bueno-de-Mesquita HB, Roddam A, Stolzenberg-Solomon R, Halkjaer J, Tjønneland A, Overvad K, Clavel-Chapelon F, Boutron-Ruault MC, Boeing H, Pischon T, Linseisen J, Rohrmann S, Trichopoulou A, Benetou V, Papadimitriou A, Pala V, Palli D, Panico S, Tumino R, Vineis P, Boshuizen HC, Ocké MC, Peeters PH, Lund E, González CA, Larrañaga N, Martinez-Garcia C, Mendez M, Navarro C, Quirós JR, Tormo MJ, Hallmans G, Ye W, Bingham SA, Khaw KT, Allen N, Key TJ, Jenab M, Norat T, Ferrari P, and Riboli E

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. May 2006

(DOI : 10.1158/1055-9965.EPI-05-0800)

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance.

Agostini M, Schoenmakers E, Mitchell C, Szatmari I, Savage D, Smith A, Rajanayagam O, Semple R, Luan J, Bath L, Zalin A, Labib M, Kumar S, Simpson H, Blom D, Marais D, Schwabe J, Barroso I, Trembath R, Wareham N, Nagy L, Gurnell M, O'Rahilly S, and Chatterjee K

Cell metabolism. May 2006

(DOI : 10.1016/j.cmet.2006.09.003)

Metformin treatment to prevent early puberty in girls with precocious pubarche.

Ibáñez L, Ong K, Valls C, Marcos MV, Dunger DB, and de Zegher F

The Journal of clinical endocrinology and metabolism. May 2006

(DOI : 10.1210/jc.2006-0336)

Psychosocial factors and asthma in a community sample of older adults.

Wainwright NW, Surtees PG, Wareham NJ, and Harrison BD

Journal of psychosomatic research. May 2006

(DOI : 10.1016/j.jpsychores.2006.10.013)

Effects of growth hormone treatment on neutrophil count in children born small for gestational age.

Ibáñez L, Ong K, Dunger DB, and Zegher Fd

Pediatrics. May 2006

(DOI : 10.1542/peds.2006-0022)

Does physical activity equally predict gain in fat mass among obese and nonobese young adults?

Ekelund U, Särnblad S, Brage S, Ryberg J, Wareham NJ, and Åman J

International Journal of Obesity. May 2006

(DOI : 10.1038/sj.ijo.0803361)

Comparison of two methods of measuring physical activity in South African older adults.

Kolbe-Alexander TL, Lambert EV, Harkins JB, and Ekelund U

Journal of Aging and Physical Activity. May 2006

Breast cancer risk in relation to abortion: Results from the EPIC study.

Reeves GK, Kan SW, Key T, Tjønneland A, Olsen A, Overvad K, Peeters PH, Clavel-Chapelon F, Paoletti X, Berrino F, Krogh V, Palli D, Tumino R, Panico S, Vineis P, González CA, Ardanaz E, Martínez C, Amiano P, Quirós JR, Tormo MR, Khaw KT, Trichopoulou A, Psaltopoulou T, Kalapothaki V, Nagel G, Chang-Claude J, Boeing H, Lahmann PH, Wirfält E, Kaaks R, and Riboli E

International journal of cancer. Apr 2006

(DOI : 10.1002/ijc.22001)

Sex-discordant associations with adiponectin levels and lipid profiles in children.

Ong KK, Frystyk J, Flyvbjerg A, Petry CJ, Ness A, and Dunger DB

Diabetes. Apr 2006

(DOI : 10.2337/db05-1272)

Growth hormone binding protein levels in children are associated with birth weight, postnatal weight gain, and insulin secretion.

Ong KK, Elmlinger M, Jones R, Emmett P, Holly J, Ranke MB, and Dunger DB

Metabolism: clinical and experimental. Apr 2006

(DOI : 10.1016/j.metabol.2007.06.004)

Size at birth, postnatal growth and risk of obesity.

and Ong KK

Hormone research. Apr 2006

(DOI : 10.1159/000091508)

The insulin gene variable number of tandem repeat: associations and interactions with childhood body fat mass and insulin secretion in normal children.

Heude B, Petry CJ, Pembrey M, Dunger DB, and Ong KK

The Journal of clinical endocrinology and metabolism. Apr 2006

(DOI : 10.1210/jc.2005-2055)

The brain-derived neurotrophic factor Val66Met polymorphism is associated with sense of coherence in a non-clinical community sample of 7335 adults.

Surtees PG, Wainwright NW, Willis-Owen SA, Sandhu MS, Luben R, Day NE, and Flint J

Journal of psychiatric research. Apr 2006

(DOI : 10.1016/j.jpsychires.2006.05.015)

Serum C-peptide levels and breast cancer risk: results from the European Prospective Investigation into Cancer and Nutrition (EPIC).

Verheus M, Peeters PH, Rinaldi S, Dossus L, Biessy C, Olsen A, Tjønneland A, Overvad K, Jeppesen M, Clavel-Chapelon F, Tehard B, Nagel G, Linseisen J, Boeing H, Lahmann PH, Arvaniti A, Psaltopoulou T, Trichopoulou A, Palli D, Tumino R, Panico S, Sacerdote C, Sieri S, van Gils CH, Bueno-de-Mesquita BH, González CA, Ardanaz E, Larrañaga N, Garcia CM, Navarro C, Quirós JR, Key T, Allen N, Bingham S, Khaw KT, Slimani N, Riboli E, and Kaaks R

International journal of cancer. Mar 2006

(DOI : 10.1002/ijc.21861)

Ekelund U, Sepp H, Brage S, Becker W, Jakes R, Hennings M, and Wareham NJ

Public Health Nutrition. Mar 2006

(DOI : S1368980006000462)

Influence of estrogen receptor alpha and progesterone receptor polymorphisms on the effects of hormone therapy on mammographic density.

van Duijnhoven FJ, Peeters PH, Warren RM, Bingham SA, Uitterlinden AG, van Noord PA, Monninkhof EM, Grobbee DE, and van Gils CH

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Mar 2006

(DOI : 10.1158/1055-9965.EPI-05-0754)

Early development of adiposity and insulin resistance after catch-up weight gain in small-for-gestational-age children.

Ibáñez L, Ong K, Dunger DB, and de Zegher F

The Journal of clinical endocrinology and metabolism. Mar 2006

(DOI : 10.1210/jc.2005-2778)

Dietary energy intake at the age of 4 months predicts postnatal weight gain and childhood body mass index.

Ong KK, Emmett PM, Noble S, Ness A, and Dunger DB

Pediatrics. Mar 2006

(DOI : 10.1542/peds.2005-1668)

Genetic variants in epigenetic genes and breast cancer risk.

Cebrian A, Pharoah PD, Ahmed S, Ropero S, Fraga MF, Smith PL, Conroy D, Luben R, Perkins B, Easton DF, Dunning AM, Esteller M, and Ponder BA