MRC Epidemiology Unit

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There are 1731 publications that match the search string

page => 17
programme => Aetiology and Mechanisms of Diabetes and Related Metabolic Disorders of Later Life

Usefulness of microalbuminuria versus the metabolic syndrome as a predictor of cardiovascular disease in women and men>40 years of age (from the Rancho Bernardo Study).

Jassal SK, Langenberg C, von Mühlen D, Bergstrom J, Barrett-Connor E

The American journal of cardiology Aug 2007

(DOI : 10.1016/j.amjcard.2007.12.030)

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.

Franks PW, Rolandsson O, Debenham SL, Fawcett KA, Payne F, Dina C, Froguel P, Mohlke KL, Willer C, Olsson T, Wareham NJ, Hallmans G, Barroso I, Sandhu MS

Diabetologia Aug 2007

(DOI : 10.1007/s00125-007-0887-6)

Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program.

Florez JC, Jablonski KA, McAteer J, Sandhu MS, Wareham NJ, Barroso I, Franks PW, Altshuler D, Knowler WC

Diabetologia Aug 2007

(DOI : 10.1007/s00125-007-0891-x)

Epidemiologic assessment of sugars consumption using biomarkers: comparisons of obese and nonobese individuals in the European prospective investigation of cancer Norfolk.

Bingham S, Luben R, Welch A, Tasevska N, Wareham NJ, Khaw KT

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology Aug 2007

(DOI : 10.1158/1055-9965.EPI-06-1050)

Differential and correlation analyses of microarray gene expression data in the CEPH Utah families.

Tan Q, Zhao J, Li S, Christiansen L, Kruse TA, Christensen K

Genomics Aug 2007

(DOI : 10.1016/j.ygeno.2008.04.001)

Past oral contraceptive and hormone therapy use and endogenous hormone concentrations in postmenopausal women.

Chan MF, Dowsett M, Folkerd E, Wareham N, Luben R, Welch A, Bingham S, Khaw KT

Menopause (New York, N.Y.) Aug 2007

(DOI : 10.1097/gme.0b013e31806458d9)

High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies.

van der Steeg WA, Holme I, Boekholdt SM, Larsen ML, Lindahl C, Stroes ES, Tikkanen MJ, Wareham NJ, Faergeman O, Olsson AG, Pedersen TR, Khaw KT, Kastelein JJ

Journal of the American College of Cardiology Jul 2007

(DOI : 10.1016/j.jacc.2007.09.060)

Combined impact of health behaviours and mortality in men and women: the EPIC-Norfolk prospective population study.

Khaw KT, Wareham NJ, Bingham S, Welch A, Luben R, Day N

PLoS Medicine Jul 2007

(DOI : 10.1371/journal.pmed.0050012)

Socioeconomic position and risk of short-term weight gain: prospective study of 14,619 middle-aged men and women.

Purslow LR, Young EH, Wareham NJ, Forouhi N, Brunner EJ, Luben RN, Welch AA, Khaw KT, Bingham SA, Sandhu MS

BMC Public Health Jul 2007

(DOI : 10.1186/1471-2458-8-112)

Epidemiological studies of physical activity and diabetes risk, and implications for diabetes prevention.

Wareham NJ

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme Jul 2007

(DOI : 10.1139/H07-032)

Clustering of metabolic risk factors in young adults: genes and environment.

Peeters MW, Thomis MA, Loos RJ, Derom CA, Fagard R, Vlietinck RF, Beunen GP

Atherosclerosis Jul 2007

(DOI : 10.1016/j.atherosclerosis.2007.11.024)

Self-reported mental health-related quality of life and mortality in men and women in the European Prospective Investigation into Cancer (EPIC-Norfolk): a prospective population study.

Myint PK, Luben RN, Surtees PG, Wainwright NW, Welch AA, Bingham SA, Wareham NJ, Smith RD, Harvey IM, Khaw KT

Psychosomatic medicine Jun 2007

(DOI : 10.1097/psy.0b013e318068fcd4)

Hormone replacement therapy and symptomatic gallstones - a prospective population study in the EPIC-Norfolk cohort.

Hart AR, Luben R, Welch A, Bingham S, Khaw KT

Digestion Jun 2007

(DOI : 10.1159/000113897)

Increase in physical activity energy expenditure is associated with reduced metabolic risk independent of change in fatness and fitness.

Ekelund U, Franks PW, Sharp SJ, Brage S, Wareham NJ

Diabetes care May 2007

(DOI : 10.2337/dc07-0719)

Usual physical activity and endogenous sex hormones in postmenopausal women: the European prospective investigation into cancer-norfolk population study.

Chan MF, Dowsett M, Folkerd E, Bingham S, Wareham NJ, Luben R, Welch A, Khaw KT

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology May 2007

(DOI : 10.1158/1055-9965.EPI-06-0745)

Phytoestrogen exposure is associated with circulating sex hormone levels in postmenopausal women and interact with ESR1 and NR1I2 gene variants.

Low YL, Dunning AM, Dowsett M, Folkerd E, Doody D, Taylor J, Bhaniani A, Luben R, Khaw KT, Wareham NJ, Bingham SA

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology May 2007

(DOI : 10.1158/1055-9965.EPI-06-0899)

Do simple questions about diet and physical activity help to identify those at risk of Type 2 diabetes?

Simmons RK, Harding AH, Wareham NJ, Griffin SJ

Diabetic medicine : a journal of the British Diabetic Association May 2007

(DOI : 10.1111/j.1464-5491.2007.02173.x)

Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women.

Heude B, Ong KK, Luben R, Wareham NJ, Sandhu MS

The Journal of clinical endocrinology and metabolism May 2007

(DOI : 10.1210/jc.2006-1948)

Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities.

Souren NY, Paulussen AD, Loos RJ, Gielen M, Beunen G, Fagard R, Derom C, Vlietinck R, Zeegers MP

Diabetologia May 2007

(DOI : 10.1007/s00125-007-0784-z)

Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-Norfolk.

van der Steeg WA, Boekholdt SM, Stein EA, El-Harchaoui K, Stroes ES, Sandhu MS, Wareham NJ, Jukema JW, Luben R, Zwinderman AH, Kastelein JJ, Khaw KT

Annals of internal medicine May 2007

(DOI : 10.7326/0003-4819-146-9-200705010-00007)

Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity.

Brage S, Ekelund U, Brage N, Hennings MA, Froberg K, Franks PW, Wareham NJ

Journal of applied physiology (Bethesda, Md. : 1985) Apr 2007

(DOI : 10.1152/japplphysiol.00092.2006)

A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.

Savage DB, Zhai L, Ravikumar B, Choi CS, Snaar JE, McGuire AC, Wou SE, Medina-Gomez G, Kim S, Bock CB, Segvich DM, Solanky B, Deelchand D, Vidal-Puig A, Wareham NJ, Shulman GI, Karpe F, Taylor R, Pederson BA, Roach PJ, O'Rahilly S, DePaoli-Roach AA

PLoS Medicine Apr 2007

(DOI : 10.1371/journal.pmed.0050027)

Lack of association between the Pro12Ala polymorphism of the PPAR-gamma 2 gene and type 2 diabetes mellitus in the Qatari consanguineous population.

Badii R, Bener A, Zirie M, Al-Rikabi A, Simsek M, Al-Hamaq AO, Ghoussaini M, Froguel P, Wareham NJ

Acta diabetologica Apr 2007

(DOI : 10.1007/s00592-007-0013-8)

The Collaborative Study of Obesity and Diabetes in Adults (CODA) project: meta-analysis design and description of participating studies.

Duval S, Vazquez G, Baker WL, Jacobs DR

Obesity reviews : an official journal of the International Association for the Study of Obesity Apr 2007

(DOI : 10.1111/j.1467-789X.2006.00263.x)

Psychosocial factors and incident asthma hospital admissions in the EPIC-Norfolk cohort study.

Wainwright NW, Surtees PG, Wareham NJ, Harrison BD

Allergy Apr 2007

(DOI : 10.1111/j.1398-9995.2007.01316.x)

Retrospective analysis of main and interaction effects in genetic association studies of human complex traits.

Tan Q, Christiansen L, Brasch-Andersen C, Zhao JH, Li S, Kruse TA, Christensen K

BMC genetics Apr 2007

(DOI : 10.1186/1471-2156-8-70)

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.

Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JR, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch AM, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Järvelin MR, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJ, Barroso I, Wareham NJ, Karpe F, Owen KR, Cardon LR, Walker M, Hitman GA, Palmer CN, Doney AS, Morris AD, Smith GD, Hattersley AT, McCarthy MI

Science (New York, N.Y.) Apr 2007

(DOI : 10.1126/science.1141634)

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.

Loos RJ, Franks PW, Francis RW, Barroso I, Gribble FM, Savage DB, Ong KK, O'Rahilly S, Wareham NJ

Diabetes Apr 2007

(DOI : 10.2337/db07-0055)

Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations.

Meirhaeghe A, Sandhu MS, McCarthy MI, de Groote P, Cottel D, Arveiler D, Ferrières J, Groves CJ, Hattersley AT, Hitman GA, Walker M, Wareham NJ, Amouyel P

Human Molecular Genetics Apr 2007

(DOI : 10.1093/hmg/ddm084)

Adaptation to social adversity is associated with stroke incidence: evidence from the EPIC-Norfolk prospective cohort study.

Surtees PG, Wainwright NW, Luben RL, Wareham NJ, Bingham SA, Khaw KT

Stroke Mar 2007

(DOI : 10.1161/STROKEAHA.106.473116)

The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals.

Young EH, Wareham NJ, Farooqi S, Hinney A, Hebebrand J, Scherag A, O'Rahilly S, Barroso I, Sandhu MS

International Journal of Obesity Mar 2007

(DOI : 10.1038/sj.ijo.0803609)

Heritability of somatotype components: a multivariate analysis.

Peeters MW, Thomis MA, Loos RJ, Derom CA, Fagard R, Claessens AL, Vlietinck RF, Beunen GP

International Journal of Obesity Mar 2007

(DOI : 10.1038/sj.ijo.0803575)

Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.

Tan K, Kimber WA, Luan J, Soos MA, Semple RK, Wareham NJ, O'Rahilly S, Barroso I

Diabetes Mar 2007

(DOI : 10.2337/db06-0921)

Lamin A/C polymorphisms, type 2 diabetes, and the metabolic syndrome: case-control and quantitative trait studies.

Mesa JL, Loos RJ, Franks PW, Ong KK, Luan J, O'Rahilly S, Wareham NJ, Barroso I

Diabetes Mar 2007

(DOI : 10.2337/db06-1055)

Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies.

Semple RK, Halberg NH, Burling K, Soos MA, Schraw T, Luan J, Cochran EK, Dunger DB, Wareham NJ, Scherer PE, Gorden P, O'Rahilly S

Diabetes Feb 2007

(DOI : 10.2337/db06-1665)

Physical activity and obesity prevention.

Wareham NJ

Obesity reviews : an official journal of the International Association for the Study of Obesity Feb 2007

(DOI : 10.1111/j.1467-789X.2007.00328.x)

Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study.

Mallat Z, Benessiano J, Simon T, Ederhy S, Sebella-Arguelles C, Cohen A, Huart V, Wareham NJ, Luben R, Khaw KT, Tedgui A, Boekholdt SM

Arteriosclerosis, thrombosis, and vascular biology Feb 2007

(DOI : 10.1161/ATVBAHA.107.139352)

Physical activity and fibrinogen concentrations in 23,201 men and women in the EPIC-Norfolk population-based study.

Myint PK, Luben RN, Wareham NJ, Welch AA, Bingham SA, Khaw KT

Atherosclerosis Feb 2007

(DOI : 10.1016/j.atherosclerosis.2007.09.021)

Genome-wide association study identifies novel breast cancer susceptibility loci.

Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R, Wareham NJ, Ahmed S, Healey CS, Bowman R, Meyer KB, Haiman CA, Kolonel LK, Henderson BE, Le Marchand L, Brennan P, Sangrajrang S, Gaborieau V, Odefrey F, Shen CY, Wu PE, Wang HC, Eccles D, Evans DG, Peto J, Fletcher O, Johnson N, Seal S, Stratton MR, Rahman N, Chenevix-Trench G, Bojesen SE, Nordestgaard BG, Axelsson CK, García-Closas M, Brinton L, Chanock S, Lissowska J, Peplonska B, Nevanlinna H, Fagerholm R, Eerola H, Kang D, Yoo KY, Noh DY, Ahn SH, Hunter DJ, Hankinson SE, Cox DG, Hall P, Wedren S, Liu J, Low YL, Bogdanova N, Schürmann P, Dörk T, Tollenaar RA, Jacobi CE, Devilee P, Klijn JG, Sigurdson AJ, Doody MM, Alexander BH, Zhang J, Cox A, Brock IW, MacPherson G, Reed MW, Couch FJ, Goode EL, Olson JE, Meijers-Heijboer H, van den Ouweland A, Uitterlinden A, Rivadeneira F, Milne RL, Ribas G, González-Neira A, Benitez J, Hopper JL, McCredie M, Southey M, Giles GG, Schroen C, Justenhoven C, Brauch H, Hamann U, Ko YD, Spurdle AB, Beesley J, Chen X, Mannermaa A, Kosma VM, Kataja V, Hartikainen J, Day NE, Cox DR, Ponder BA

Nature Feb 2007

(DOI : 10.1038/nature05887)

Common variants in WFS1 confer risk of type 2 diabetes.

Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, Daly A, Lango H, Frayling TM, Neumann RJ, Sherva R, Blech I, Pharoah PD, Palmer CN, Kimber C, Tavendale R, Morris AD, McCarthy MI, Walker M, Hitman G, Glaser B, Permutt MA, Hattersley AT, Wareham NJ, Barroso I

Nature genetics Feb 2007

(DOI : 10.1038/ng2067)

Gene-lifestyle interaction on risk of type 2 diabetes

Wareham NJ, Franks PW, Mesa JL, Harding AH

Nutrition, Metabolism & Cardiovascular Diseases Feb 2007

(DOI : 10.1016/j.numecd.2006.04.001)

Effects of physical activity on evolution of proximal femur structure in a younger elderly population

Wareham NJ, Khaw KT, Kaptoge S, Jakes RW, Dalzell N, Loveridge N, Beck TJ, Reeve J

Bone Feb 2007

(DOI : 10.1016/j.bone.2006.09.021)

Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies

Wareham NJ, Bingham SA, Boekholdt SM, Khaw KT, Sarwar N, Danesh J, Eiriksdottir G, Sigurdsson G, Gudnason V

Circulation Jan 2007

(DOI : 10.1161/CIRCULATIONAHA.106.637793)

Incidence of Type 2 diabetes in England and its association with baseline impaired fasting glucose: the Ely study 1990-2000.

Forouhi NG, Luan J, Hennings S, Wareham NJ

Diabetic medicine : a journal of the British Diabetic Association Jan 2007

(DOI : 10.1111/j.1464-5491.2007.02068.x)

Physical activity and metabolic risk in individuals with a family history of type 2 diabetes.

Ekelund U, Griffin SJ, Wareham NJ

Diabetes care Jan 2007

(DOI : 10.2337/dc06-1883)

Physical activity energy expenditure may mediate the relationship between plasma leptin levels and worsening insulin resistance independently of adiposity.

Franks PW, Loos RJ, Brage S, O'Rahilly S, Wareham NJ, Ekelund U

Journal of applied physiology (Bethesda, Md. : 1985) Jan 2007

(DOI : 10.1152/japplphysiol.01022.2006)

Comment on "A common genetic variant is associated with adult and childhood obesity".

Loos RJ, Barroso I, O'Rahilly S, Wareham NJ

Science (New York, N.Y.) Jan 2007

(DOI : 10.1126/science.1130012)

Fruit and vegetable consumption and self-reported functional health in men and women in the European Prospective Investigation into Cancer-Norfolk (EPIC-Norfolk): a population-based cross-sectional study.

Myint PK, Welch AA, Bingham SA, Surtees PG, Wainwright NW, Luben RN, Wareham NJ, Smith RD, Harvey IM, Day NE, Khaw KT

Public Health Nutrition Jan 2007

(DOI : 10.1017/S1368980007222608)

Glycated hemoglobin and risk of stroke in people without known diabetes in the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study: a threshold relationship?

Myint PK, Sinha S, Wareham NJ, Bingham SA, Luben RN, Welch AA, Khaw KT

Stroke Jan 2007

(DOI : 10.1161/01.STR.0000254549.75763.5f)

The emergence of networks in human genome epidemiology: challenges and opportunities.

Seminara D, Khoury MJ, O'Brien TR, Manolio T, Gwinn ML, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam AP, Danesh J, Davey Smith G, Dolan S, Duncan R, Gruis NA, Hashibe M, Hunter D, Järvelin MR, Malmer B, Maraganore DM, Newton-Bishop JA, Riboli E, Salanti G, Taioli E, Timpson N, Uitterlinden AG, Vineis P, Wareham NJ, Winn DM, Zimmern R, Ioannidis JP

Epidemiology (Cambridge, Mass.) Dec 2006

(DOI : 10.1097/01.ede.0000249540.17855.b7)

Comparison of different definitions of the metabolic syndrome in relation to cardiovascular mortality in European men and women

DECODE Study Group

Diabetologia Dec 2006

(DOI : 10.1007/s00125-006-0438-6)

Physical activity, C-reactive protein levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study

Wareham NJ, Bingham SA, Boekholdt SM, Day NE, Khaw KT, Luben RN, Peters RJ, Sandhu MS

European Journal of Preventive Cardiology Dec 2006

(DOI : 10.1097/01.hjr.0000209811.97948.07)

Glycated hemoglobin as a marker of cardiovascular risk

Wareham NJ, Khaw KT

Current opinion in lipidology Dec 2006

(DOI : 10.1097/MOL.0b013e3280106b95)

Dietary fish intake and plasma phospholipid n-3 polyunsaturated fatty acid concentrations in men and women in the European Prospective Investigation into Cancer-Norfolk United Kingdom cohort

Wareham NJ, Bingham SA, Khaw KT, Ive J, Friesen MD, Riboli E, Welch AA

The American Journal of Clinical Nutrition Dec 2006

(DOI : 10.1093/ajcn/84.6.1330)

Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study.

Meuwese MC, Stroes ES, Hazen SL, van Miert JN, Kuivenhoven JA, Schaub RG, Wareham NJ, Luben R, Kastelein JJ, Khaw KT, Boekholdt SM

Journal of the American College of Cardiology Nov 2006

(DOI : 10.1016/j.jacc.2007.03.033)

Elevated serum ferritin levels predict new-onset type 2 diabetes: results from the EPIC-Norfolk prospective study.

Forouhi NG, Harding AH, Allison M, Sandhu MS, Welch A, Luben R, Bingham S, Khaw KT, Wareham NJ

Diabetologia Nov 2006

(DOI : 10.1007/s00125-007-0604-5)

EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries.

Danesh J, Saracci R, Berglund G, Feskens E, Overvad K, Panico S, Thompson S, Fournier A, Clavel-Chapelon F, Canonico M, Kaaks R, Linseisen J, Boeing H, Pischon T, Weikert C, Olsen A, Tjønneland A, Johnsen SP, Jensen MK, Quirós JR, Svatetz CA, Pérez MJ, Larrañaga N, Sanchez CN, Iribas CM, Bingham S, Khaw KT, Wareham NJ, Key T, Roddam A, Trichopoulou A, Benetou V, Trichopoulos D, Masala G, Sieri S, Tumino R, Sacerdote C, Mattiello A, Verschuren WM, Bueno-de-Mesquita HB, Grobbee DE, van der Schouw YT, Melander O, Hallmans G, Wennberg P, Lund E, Kumle M, Skeie G, Ferrari P, Slimani N, Norat T, Riboli E

European Journal of Epidemiology Nov 2006

(DOI : 10.1007/s10654-006-9096-8)

Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes

Wareham NJ, Harding AH, Luan J, O'Rahilly S, Barroso I

Diabetologia Nov 2006

(DOI : 10.1007/s00125-006-0430-1)

Plasma levels of plant sterols and the risk of coronary artery disease: the prospective EPIC-Norfolk Population Study

Wareham NJ, Boekholdt SM, Kastelein JJ, Khaw KT, Luben RN, Vissers PAJ, Pinedo S, Von Bergmann K, Elharchaoui K, Lütjohann D

Journal of lipid research Oct 2006

(DOI : 10.1194/jlr.M600371-JLR200)

PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge.

Franks PW, Ekelund U, Brage S, Luan J, Schafer AJ, O'Rahilly S, Barroso I, Wareham NJ

Diabetologia Oct 2006

(DOI : 10.1007/s00125-006-0580-1)

Association of weight gain in infancy and early childhood with metabolic risk in young adults.

Ekelund U, Ong KK, Linné Y, Neovius M, Brage S, Dunger DB, Wareham NJ, Rössner S

The Journal of clinical endocrinology and metabolism Oct 2006

(DOI : 10.1210/jc.2006-1071)

PGC-1alpha gene and physical activity in type 2 diabetes mellitus

Franks PW, Loos R

Exercise and sport sciences reviews Oct 2006

(DOI : 10.1249/01.jes.0000240021.92254.23)

Habitual fish consumption and risk of incident stroke: the European Prospective Investigation into Cancer (EPIC)-Norfolk prospective population study.

Myint PK, Welch AA, Bingham SA, Luben RN, Wareham NJ, Day NE, Khaw KT

Public Health Nutrition Oct 2006

(DOI : 10.1017/phn2006942)

PARL Leu262Val is not associated with fasting insulin levels in UK populations

Wareham NJ, Barroso I, Cooper C, Day NE, Luan J, O'Rahilly S, Sandhu MS, Fawcett KA, Syddall H

Diabetologia Sep 2006

(DOI : 10.1007/s00125-006-0443-9)

Implications of gene-environment interaction in studies of gene variants in breast cancer: an example of dietary isoflavones and the D356N polymorphism in the sex hormone-binding globulin gene.

Low YL, Dunning AM, Dowsett M, Luben RN, Khaw KT, Wareham NJ, Bingham SA

Cancer research Sep 2006

(DOI : 10.1158/0008-5472.CAN-06-2432)

Compensatory mammary growth following protein restriction during pregnancy and lactation increases early-onset mammary tumor incidence in rats.

Fernandez-Twinn DS, Ekizoglou S, Gusterson BA, Luan J, Ozanne SE

Carcinogenesis Sep 2006

(DOI : 10.1093/carcin/bgl166)

Combined work and leisure physical activity and risk of stroke in men and women in the European prospective investigation into Cancer-Norfolk Prospective Population Study.

Myint PK, Luben RN, Wareham NJ, Welch AA, Bingham SA, Day NE, Khaw KT

Neuroepidemiology Sep 2006

(DOI : 10.1159/000095551)

Tissue factor serum levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.

Keller TT, Choi D, Nagel C, Te Velthuis H, Gerdes VE, Wareham NJ, Bingham SA, Luben R, Hack CE, Reitsma PH, Levi M, Khaw KT, Boekholdt SM

Journal of thrombosis and haemostasis : JTH Aug 2006

(DOI : 10.1111/j.1538-7836.2006.02190.x)

Plasma concentrations of ascorbic acid and C-reactive protein, and risk of future coronary artery disease, in apparently healthy men and women: the EPIC-Norfolk prospective population study.

Boekholdt SM, Meuwese MC, Day NE, Luben R, Welch A, Wareham NJ, Khaw KT

The British journal of nutrition Aug 2006

(DOI : S0007114506002583)

Studies of the SIM1 gene in relation to human obesity and obesity-related traits.

Hung CC, Luan J, Sims M, Keogh JM, Hall C, Wareham NJ, O'Rahilly S, Farooqi IS

International Journal of Obesity Aug 2006

(DOI : 10.1038/sj.ijo.0803443)

Association of alpha-synuclein gene haplotypes with Parkinson's disease.

Parsian AJ, Racette BA, Zhao JH, Sinha R, Patra B, Perlmutter JS, Parsian A

Parkinsonism & related disorders Aug 2006

(DOI : 10.1016/j.parkreldis.2006.12.006)

Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women.

Keller TT, van Leuven SI, Meuwese MC, Wareham NJ, Luben R, Stroes ES, Hack CE, Levi M, Khaw KT, Boekholdt SM

Arteriosclerosis, thrombosis, and vascular biology Aug 2006

(DOI : 10.1161/01.ATV.0000240517.69201.77)

Physical activity and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition Cohort.

Steindorf K, Friedenreich C, Linseisen J, Rohrmann S, Rundle A, Veglia F, Vineis P, Johnsen NF, Tjønneland A, Overvad K, Raaschou-Nielsen O, Clavel-Chapelon F, Boutron-Ruault MC, Schulz M, Boeing H, Trichopoulou A, Kalapothaki V, Koliva M, Krogh V, Palli D, Tumino R, Panico S, Monninkhof E, Peeters PH, Boshuizen HC, Bueno-de-Mesquita HB, Chirlaque MD, Agudo A, Larrañaga N, Quirós JR, Martínez C, Barricarte A, Janzon L, Berglund G, Bingham S, Khaw KT, Key TJ, Norat T, Jenab M, Cust A, Riboli E

International journal of cancer Aug 2006

(DOI : 10.1002/ijc.22125)

Tobacco smoke and bladder cancer--in the European Prospective Investigation into Cancer and Nutrition.

Bjerregaard BK, Raaschou-Nielsen O, Sørensen M, Frederiksen K, Christensen J, Tjønneland A, Overvad K, Chapelon FC, Nagel G, Chang-Claude J, Bergmann MM, Boeing H, Trichopoulos D, Trichopoulou A, Oikonomou E, Berrino F, Palli D, Tumino R, Vineis P, Panico S, Peeters PH, Bueno-de-Mesquita HB, Kiemeney L, Gram IT, Braaten T, Lund E, González CA, Berglund G, Allen N, Roddam A, Bingham S, Riboli E

International journal of cancer Aug 2006

(DOI : 10.1002/ijc.22169)

Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study.

El Harchaoui K, van der Steeg WA, Stroes ES, Kuivenhoven JA, Otvos JD, Wareham NJ, Hutten BA, Kastelein JJ, Khaw KT, Boekholdt SM

Journal of the American College of Cardiology Aug 2006

(DOI : 10.1016/j.jacc.2006.09.043)

Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions.

Ong KK, Loos RJ

Acta paediatrica (Oslo, Norway : 1992) Aug 2006

(DOI : 10.1080/08035250600719754)

Fibrinogen plasma levels modify the association between the factor XIII Val34Leu variant and risk of coronary artery disease: the EPIC-Norfolk prospective population study.

Boekholdt SM, Sandhu MS, Wareham NJ, Luben R, Reitsma PH, Khaw KT

Journal of thrombosis and haemostasis : JTH Aug 2006

(DOI : 10.1111/j.1538-7836.2006.02154.x)

Twin birth weight standards.

Gielen M, Lindsey PJ, Derom C, Loos RJ, Derom R, Nijhuis JG, Vlietinck R

Neonatology Aug 2006

(DOI : 10.1159/000102055)

Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.

Collins SC, Luan J, Thompson AJ, Daly A, Semple RK, O'Rahilly S, Wareham NJ, Barroso I

Diabetologia Jul 2006

(DOI : 10.1007/s00125-006-0534-7)

Obesity indices and self-reported functional health in men and women in the EPIC-Norfolk.

Myint PK, Welch AA, Luben RN, Wainwright NW, Surtees PG, Bingham SA, Wareham NJ, Smith RD, Harvey IM, Khaw KT

Obesity (Silver Spring, Md.) Jul 2006

(DOI : 10.1038/oby.2006.102)

Genetic variants and common diseases--better late than never.

O'Rahilly S, Wareham NJ

The New England journal of medicine Jul 2006

(DOI : 10.1056/NEJMe068140)

Temporal trends in physical activity in England: the Health Survey for England 1991 to 2004.

Stamatakis E, Ekelund U, Wareham NJ

Preventive Medicine Jul 2006

(DOI : 10.1016/j.ypmed.2006.12.014)

Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study.

Vaessen SF, Schaap FG, Kuivenhoven JA, Groen AK, Hutten BA, Boekholdt SM, Hattori H, Sandhu MS, Bingham SA, Luben R, Palmen JA, Wareham NJ, Humphries SE, Kastelein JJ, Talmud PJ, Khaw KT

Journal of lipid research Jun 2006

(DOI : 10.1194/jlr.M600233-JLR200)

Work and leisure time physical activity assessed using a simple, pragmatic, validated questionnaire and incident cardiovascular disease and all-cause mortality in men and women: The European Prospective Investigation into Cancer in Norfolk prospective population study.

Khaw KT, Jakes R, Bingham S, Welch A, Luben R, Day N, Wareham NJ

International Journal of Epidemiology May 2006

(DOI : 10.1093/ije/dyl079)

Elevated plasma adiponectin in humans with genetically defective insulin receptors.

Semple RK, Soos MA, Luan J, Mitchell CS, Wilson JC, Gurnell M, Cochran EK, Gorden P, Chatterjee VK, Wareham NJ, O'Rahilly S

The Journal of clinical endocrinology and metabolism May 2006

(DOI : 10.1210/jc.2006-0166)

Non-DNA binding, dominant-negative, human PPARgamma mutations cause lipodystrophic insulin resistance.

Agostini M, Schoenmakers E, Mitchell C, Szatmari I, Savage D, Smith A, Rajanayagam O, Semple R, Luan J, Bath L, Zalin A, Labib M, Kumar S, Simpson H, Blom D, Marais D, Schwabe J, Barroso I, Trembath R, Wareham N, Nagy L, Gurnell M, O'Rahilly S, Chatterjee K

Cell metabolism May 2006

(DOI : 10.1016/j.cmet.2006.09.003)

Psychosocial factors and asthma in a community sample of older adults.

Wainwright NW, Surtees PG, Wareham NJ, Harrison BD

Journal of psychosomatic research May 2006

(DOI : 10.1016/j.jpsychores.2006.10.013)

Does physical activity equally predict gain in fat mass among obese and nonobese young adults?

Ekelund U, Särnblad S, Brage S, Ryberg J, Wareham NJ, Åman J

International Journal of Obesity May 2006

(DOI : 10.1038/sj.ijo.0803361)

Breast cancer risk in relation to abortion: Results from the EPIC study.

Reeves GK, Kan SW, Key T, Tjønneland A, Olsen A, Overvad K, Peeters PH, Clavel-Chapelon F, Paoletti X, Berrino F, Krogh V, Palli D, Tumino R, Panico S, Vineis P, González CA, Ardanaz E, Martínez C, Amiano P, Quirós JR, Tormo MR, Khaw KT, Trichopoulou A, Psaltopoulou T, Kalapothaki V, Nagel G, Chang-Claude J, Boeing H, Lahmann PH, Wirfält E, Kaaks R, Riboli E

International journal of cancer Apr 2006

(DOI : 10.1002/ijc.22001)

Serum C-peptide levels and breast cancer risk: results from the European Prospective Investigation into Cancer and Nutrition (EPIC).

Verheus M, Peeters PH, Rinaldi S, Dossus L, Biessy C, Olsen A, Tjønneland A, Overvad K, Jeppesen M, Clavel-Chapelon F, Tehard B, Nagel G, Linseisen J, Boeing H, Lahmann PH, Arvaniti A, Psaltopoulou T, Trichopoulou A, Palli D, Tumino R, Panico S, Sacerdote C, Sieri S, van Gils CH, Bueno-de-Mesquita BH, González CA, Ardanaz E, Larrañaga N, Garcia CM, Navarro C, Quirós JR, Key T, Allen N, Bingham S, Khaw KT, Slimani N, Riboli E, Kaaks R

International journal of cancer Mar 2006

(DOI : 10.1002/ijc.21861)

Ekelund U, Sepp H, Brage S, Becker W, Jakes R, Hennings M, Wareham NJ

Public Health Nutrition Mar 2006

(DOI : S1368980006000462)

Upward weight percentile crossing in infancy and early childhood independently predicts fat mass in young adults: the Stockholm Weight Development Study (SWEDES).

Ekelund U, Ong K, Linné Y, Neovius M, Brage S, Dunger DB, Wareham NJ, Rössner S

The American Journal of Clinical Nutrition Feb 2006

(DOI : 10.1093/ajcn/83.2.324)

Dietary antioxidants and asthma in adults.

Patel BD, Welch AA, Bingham SA, Luben RN, Day NE, Khaw KT, Lomas DA, Wareham NJ

Thorax Feb 2006

(DOI : 10.1136/thx.2004.024935)

A road map for efficient and reliable human genome epidemiology.

Ioannidis JP, Gwinn M, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam A, Danesh J, Smith GD, Dolan S, Duncan R, Gruis NA, Hartge P, Hashibe M, Hunter DJ, Järvelin MR, Malmer B, Maraganore DM, Newton-Bishop JA, O'Brien TR, Petersen G, Riboli E, Salanti G, Seminara D, Smeeth L, Taioli E, Timpson N, Uitterlinden AG, Vineis P, Wareham NJ, Winn DM, Zimmern R, Khoury MJ

Nature genetics Feb 2006

Air pollution and risk of lung cancer in a prospective study in Europe.

Vineis P, Hoek G, Krzyzanowski M, Vigna-Taglianti F, Veglia F, Airoldi L, Autrup H, Dunning A, Garte S, Hainaut P, Malaveille C, Matullo G, Overvad K, Raaschou-Nielsen O, Clavel-Chapelon F, Linseisen J, Boeing H, Trichopoulou A, Palli D, Peluso M, Krogh V, Tumino R, Panico S, Bueno-de-Mesquita HB, Peeters PH, Lund EE, González CA, Martínez C, Dorronsoro M, Barricarte A, Cirera L, Quirós JR, Berglund G, Forsberg B, Day NE, Key TJ, Saracci R, Kaaks R, Riboli E

International journal of cancer Feb 2006

(DOI : 10.1002/ijc.21801)

Integrated analysis of genetic data with R.

Zhao JH, Tan Q

Human genomics Feb 2006

(DOI : PMC3525150)

Modifiable lifestyle behaviors and functional health in the European Prospective Investigation into Cancer (EPIC)-Norfolk population study.

Myint PK, Surtees PG, Wainwright NW, Wareham NJ, Bingham SA, Luben RN, Welch AA, Smith RD, Harvey IM, Khaw KT

Preventive medicine Jan 2006

(DOI : 10.1016/j.ypmed.2006.09.007)

Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels.

Bhattacharyya S, Luan J, Challis B, Keogh J, Montague C, Brennand J, Morten J, Lowenbeim S, Jenkins S, Farooqi IS, Wareham NJ, O'Rahilly S

Journal of lipid research Jan 2006

(DOI : 10.1194/jlr.M500338-JLR200)

Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC).

Weikert S, Boeing H, Pischon T, Olsen A, Tjonneland A, Overvad K, Becker N, Linseisen J, Lahmann PH, Arvaniti A, Kassapa C, Trichoupoulou A, Sieri S, Palli D, Tumino R, Vineis P, Panico S, van Gils CH, Peeters PH, Bueno-de-Mesquita HB, Büchner FL, Ljungberg B, Hallmans G, Berglund G, Wirfält E, Pera G, Dorronsoro M, Gurrea AB, Navarro C, Martínez C, Quirós JR, Allen N, Roddam A, Bingham S, Jenab M, Slimani N, Norat T, Riboli E

International journal of cancer Jan 2006

(DOI : 10.1002/ijc.21765)

Anthropometric measures, endogenous sex steroids and breast cancer risk in postmenopausal women: a study within the EPIC cohort.

Rinaldi S, Key TJ, Peeters PH, Lahmann PH, Lukanova A, Dossus L, Biessy C, Vineis P, Sacerdote C, Berrino F, Panico S, Tumino R, Palli D, Nagel G, Linseisen J, Boeing H, Roddam A, Bingham S, Khaw KT, Chloptios J, Trichopoulou A, Trichopoulos D, Tehard B, Clavel-Chapelon F, González CA, Larrañaga N, Barricarte A, Quirós JR, Chirlaque MD, Martínez C, Monninkhof E, Grobbee DE, Bueno-de-Mesquita HB, Ferrari P, Slimani N, Riboli E, Kaaks R

International journal of cancer Dec 2005

(DOI : 10.1002/ijc.21730)

Study at Cambridge

About the University

Research at Cambridge