MRC Epidemiology Unit
Holman N, Young B, Gregg EW, Wareham N, Sharp S, Khunti K, Sattar N, Valabhji J
Diabetes, obesity & metabolism. Aug 2024
(DOI : 10.1111/dom.15783)
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
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Nature. Feb 2024
(DOI : 10.1038/s41586-024-07019-6)
GDF15 linked to maternal risk of nausea and vomiting during pregnancy.
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Nature. Dec 2023
(DOI : 10.1038/s41586-023-06921-9)
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Genome biology. Dec 2022
(DOI : 10.1186/s13059-022-02837-1)
A saturated map of common genetic variants associated with human height.
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Nature. Oct 2022
(DOI : 10.1038/s41586-022-05275-y)
Metabolomic profiles predict individual multidisease outcomes.
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Nature medicine. Sep 2022
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Valabhji J, Barron E, Gorton T, Bakhai C, Kar P, Young B, Khunti K, Holman N, Sattar N, Wareham NJ
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Nature genetics. Jun 2019
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BMC cardiovascular disorders. Apr 2019
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Nature genetics. Mar 2018
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Nature genetics. Mar 2018
(DOI : 10.1038/s41588-018-0082-3)
Mahajan A, Taliun D, Thurner M, Robertson NR, Torres JM, Rayner NW, Payne AJ, Steinthorsdottir V, Scott RA, Grarup N, Cook JP, Schmidt EM, Wuttke M, Sarnowski C, Mägi R, Nano J, Gieger C, Trompet S, Lecoeur C, Preuss MH, Prins BP, Guo X, Bielak LF, Below JE, Bowden DW, Chambers JC, Kim YJ, Ng MCY, Petty LE, Sim X, Zhang W, Bennett AJ, Bork-Jensen J, Brummett CM, Canouil M, Ec Kardt KU, Fischer K, Kardia SLR, Kronenberg F, Läll K, Liu CT, Locke AE, Luan J, Ntalla I, Nylander V, Schönherr S, Schurmann C, Yengo L, Bottinger EP, Brandslund I, Christensen C, Dedoussis G, Florez JC, Ford I, Franco OH, Frayling TM, Giedraitis V, Hackinger S, Hattersley AT, Herder C, Ikram MA, Ingelsson M, Jørgensen ME, Jørgensen T, Kriebel J, Kuusisto J, Ligthart S, Lindgren CM, Linneberg A, Lyssenko V, Mamakou V, Meitinger T, Mohlke KL, Morris AD, Nadkarni G, Pankow JS, Peters A, Sattar N, Stančáková A, Strauch K, Taylor KD, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tuomilehto J, Witte DR, Dupuis J, Peyser PA, Zeggini E, Loos RJF, Froguel P, Ingelsson E, Lind L, Groop L, Laakso M, Collins FS, Jukema JW, Palmer CNA, Grallert H, Metspalu A, Dehghan A, Köttgen A, Abecasis GR, Meigs JB, Rotter JI, Marchini J, Pedersen O, Hansen T, Langenberg C, Wareham NJ, Stefansson K, Gloyn AL, Morris AP, Boehnke M, McCarthy MI
Nature genetics. Dec 2017
(DOI : 10.1038/s41588-018-0241-6)
Wood AM, Kaptoge S, Butterworth AS, Willeit P, Warnakula S, Sweeting M, Burgess S, Astle W, Koulman A, Verschuren WMM, Sato S, Njølstad I, Woodward M, Salomaa V, Nordestgaard BG, Yeap BB, Melander O, Kuller LH, Balkau B, Koenig W, Casiglia E, Cooper C, Arndt V, Franco OH, Wennberg P, Gallacher J, Völzke H, Dahm CC, Dale CE, Bergmann MM, Crespo CJ, van der Schouw YT, Kaaks R, Simons LA, Lagiou P, Boer JMA, Key TJ, Rodriguez B, Moreno-Iribas C, Davidson KW, Sacerdote C, Wallace RB, Quirós JR, Tumino R, Linneberg A, Panico S, Skeie G, Weiderpass E, Nietert PJ, Psaty BM, Kromhout D, Salamanca-Fernández E, Kiechl S, Grioni S, Palli D, Huerta JM, Price J, Sundström J, Arriola L, Travis RC, Karakatsani A, Trichopoulou A, Kühn T, Grobbee DE, Barrett-Connor E, Boeing H, Overvad K, Kauhanen J, Wareham NJ, Langenberg C, Forouhi N, Wennberg M, Cushman M, Cooper JA, Rodriguez CJ, Voortman T, Meisinger C, Tjønneland A, Brenner H, Dallongeville J, Brunner EJ, Assmann G, Trevisan M, Gillum RF, Ford I, Sattar N, Thompson SG, Ferrari P, Smith GD, Banks E, Di Angelantonio E, Danesh J
Lancet (London, England). Sep 2017
(DOI : 10.1016/S0140-6736(18)30134-X)
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Nature genetics. Aug 2017
(DOI : 10.1038/s41588-017-0011-x)
Jiang X, O'Reilly PF, Aschard H, Hsu YH, Richards JB, Dupuis J, Ingelsson E, Karasik D, Pilz S, Zheng JS, Luan J, Streeten EA, Tang W, Econs MJ, Wallaschofski H, Völzke H, Power C, McCarthy MI, Boerwinkle E, van Schoor NM, van der Velde N, Cupples LA, Vasan RS, Liu CT, Zhou Y, Ripatti S, Ohlsson C, Vandenput L, Lorentzon M, Eriksson JG, Houston DK, Kritchevsky SB, Lohman KK, Ferrucci L, Peacock M, Gieger C, Beekman M, Deelen J, Kleber ME, März W, de Boer IH, Rotter JI, Rich SS, Järvelin MR, Cavadino A, Joshi PK, Wilson JF, Hayward C, Lind L, Michaëlsson K, Trompet S, Zillikens MC, Uitterlinden AG, Rivadeneira F, Broer L, Campbell H, Tikkanen E, Lehtimäki T, Lyytikäinen LP, Kähönen M, Raitakari OT, Mikkilä V, Ikram MA, Sattar N, Jukema JW, Wareham NJ, Langenberg C, Forouhi NG, Khaw KT, Butterworth AS, Danesh J, Spector T, Hyppönen E, Kraft P, Kiel DP
Nature communications. Jul 2017
(DOI : 10.1038/s41467-017-02662-2)
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Nature genetics. May 2017
(DOI : 10.1038/s41588-018-0084-1)
Exome-wide association study of plasma lipids in >300,000 individuals.
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C, Alam D, Alves AC, Amouyel P, Di Angelantonio E, Arveiler D, Assimes TL, Auer PL, Baber U, Ballantyne CM, Bang LE, Benn M, Bis JC, Boehnke M, Boerwinkle E, Bork-Jensen J, Bottinger EP, Brandslund I, Brown M, Busonero F, Caulfield MJ, Chambers JC, Chasman DI, Chen YE, Chen YI, Chowdhury R, Christensen C, Chu AY, Connell JM, Cucca F, Cupples LA, Damrauer SM, Davies G, Deary IJ, Dedoussis G, Denny JC, Dominiczak A, Dubé MP, Ebeling T, Eiriksdottir G, Esko T, Farmaki AE, Feitosa MF, Ferrario M, Ferrières J, Ford I, Fornage M, Franks PW, Frayling TM, Frikke-Schmidt R, Fritsche LG, Frossard P, Fuster V, Ganesh SK, Gao W, Garcia ME, Gieger C, Giulianini F, Goodarzi MO, Grallert H, Grarup N, Groop L, Grove ML, Gudnason V, Hansen T, Harris TB, Hayward C, Hirschhorn JN, Holmen OL, Huffman J, Huo Y, Hveem K, Jabeen S, Jackson AU, Jakobsdottir J, Järvelin MR, Jensen GB, Jørgensen ME, Jukema JW, Justesen JM, Kamstrup PR, Kanoni S, Karpe F, Kee F, Khera AV, Klarin D, Koistinen HA, Kooner JS, Kooperberg C, Kuulasmaa K, Kuusisto J, Laakso M, Lakka T, Langenberg C, Langsted A, Launer LJ, Lauritzen T, Liewald DCM, Lin LA, Linneberg A, Loos RJF, Lu Y, Lu X, Mägi R, Malarstig A, Manichaikul A, Manning AK, Mäntyselkä P, Marouli E, Masca NGD, Maschio A, Meigs JB, Melander O, Metspalu A, Morris AP, Morrison AC, Mulas A, Müller-Nurasyid M, Munroe PB, Neville MJ, Nielsen JB, Nielsen SF, Nordestgaard BG, Ordovas JM, Mehran R, O'Donnell CJ, Orho-Melander M, Molony CM, Muntendam P, Padmanabhan S, Palmer CNA, Pasko D, Patel AP, Pedersen O, Perola M, Peters A, Pisinger C, Pistis G, Polasek O, Poulter N, Psaty BM, Rader DJ, Rasheed A, Rauramaa R, Reilly DF, Reiner AP, Renstrom F, Rich SS, Ridker PM, Rioux JD, Robertson NR, Roden DM, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sanna S, Sattar N, Schmidt EM, Scott RA, Sever P, Sevilla RS, Shaffer CM, Sim X, Sivapalaratnam S, Small KS, Smith AV, Smith BH, Somayajula S, Southam L, Spector TD, Speliotes EK, Starr JM, Stirrups KE, Stitziel N, Strauch K, Stringham HM, Surendran P, Tada H, Tall AR, Tang H, Tardif JC, Taylor KD, Trompet S, Tsao PS, Tuomilehto J, Tybjaerg-Hansen A, van Zuydam NR, Varbo A, Varga TV, Virtamo J, Waldenberger M, Wang N, Wareham NJ, Warren HR, Weeke PE, Weinstock J, Wessel J, Wilson JG, Wilson PWF, Xu M, Yaghootkar H, Young R, Zeggini E, Zhang H, Zheng NS, Zhang W, Zhang Y, Zhou W, Zhou Y, Zoledziewska M, Charge Diabetes Working Group, EPIC-InterAct Consortium, EPIC-CVD Consortium, GOLD Consortium, VA Million Veteran Program VA Million Veteran Program, Howson JMM, Danesh J, McCarthy MI, Cowan CA, Abecasis G, Deloukas P, Musunuru K, Willer CJ, Kathiresan S
Nature genetics. Jan 2017
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PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.
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Science translational medicine. Sep 2015
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Nature genetics. Jul 2015
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A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
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Human Molecular Genetics. Jul 2015
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JAMA. Jul 2015
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PLoS genetics. Nov 2014
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Tillin T, Hughes AD, Wang Q, Würtz P, Ala-Korpela M, Sattar N, Forouhi NG, Godsland IF, Eastwood SV, McKeigue PM, Chaturvedi N
Diabetologia. Nov 2014
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Lancet (London, England). Sep 2014
(DOI : 10.1016/S0140-6736(14)61183-1)
Eastwood SV, Tillin T, Dehbi HM, Wright A, Forouhi NG, Godsland I, Whincup P, Sattar N, Hughes AD, Chaturvedi N
Obesity (Silver Spring, Md.). Sep 2014
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Tillin T, Sattar N, Godsland IF, Hughes AD, Chaturvedi N, Forouhi NG
Diabetic medicine : a journal of the British Diabetic Association. Aug 2014
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BMJ (Clinical research ed.). Jul 2014
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JAMA. Mar 2014
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Nature. Nov 2013
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Tillin T, Hughes AD, Whincup P, Mayet J, Sattar N, McKeigue PM, Chaturvedi N, SABRE Study Group
Heart (British Cardiac Society). Nov 2013
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The New England journal of medicine. Oct 2012
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JAMA. Jul 2012
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Journal of the National Cancer Institute. Apr 2012
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