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Nature communications. Jul 2019
(DOI : 10.1038/s41467-019-13690-5)
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Nature genetics. Jun 2019
(DOI : PMC7610439)
Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.
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BMC cardiovascular disorders. Apr 2019
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Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
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American journal of human genetics. Feb 2019
(DOI : 10.1016/j.ajhg.2019.05.002)
MicroRNA-196a links human body fat distribution to adipose tissue extracellular matrix composition.
Hilton C, Neville MJ, Wittemans LBL, Todorčević M, Pinnick KE, Pulit SL, Luan J, Kulyté A, Dahlman I, Wareham NJ, Lotta LA, Arner P, Lindgren CM, Langenberg C, Karpe F
EBioMedicine. Feb 2019
(DOI : 10.1016/j.ebiom.2019.05.047)
Regional fat depot masses are influenced by protein-coding gene variants.
Neville MJ, Wittemans LBL, Pinnick KE, Todorčević M, Kaksonen R, Pietiläinen KH, Luan J, Scott RA, Wareham NJ, Langenberg C, Karpe F
PLoS ONE. Jan 2019
(DOI : 10.1371/journal.pone.0217644)
Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.
Lotta LA, Mokrosiński J, Mendes de Oliveira E, Li C, Sharp SJ, Luan J, Brouwers B, Ayinampudi V, Bowker N, Kerrison N, Kaimakis V, Hoult D, Stewart ID, Wheeler E, Day FR, Perry JRB, Langenberg C, Wareham NJ, Farooqi IS
Cell. Dec 2018
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Lotta LA, Wittemans LBL, Zuber V, Stewart ID, Sharp SJ, Luan J, Day FR, Li C, Bowker N, Cai L, De Lucia Rolfe E, Khaw KT, Perry JRB, O'Rahilly S, Scott RA, Savage DB, Burgess S, Wareham NJ, Langenberg C
JAMA. Dec 2018
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Associations of autozygosity with a broad range of human phenotypes.
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Nature communications. Nov 2018
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Lotta LA, Stewart ID, Sharp SJ, Day FR, Burgess S, Luan J, Bowker N, Cai L, Li C, Wittemans LBL, Kerrison ND, Khaw KT, McCarthy MI, O'Rahilly S, Scott RA, Savage DB, Perry JRB, Langenberg C, Wareham NJ
JAMA cardiology. Oct 2018
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Lotta LA, Stewart ID, Sharp SJ, Day FR, Burgess S, Luan J, Bowker N, Wittemans LBL, Kerrison ND, Khaw KT, McCarthy MI, O'Rahilly S, Scott RA, Savage DB, Perry JR, Langenberg C, Wareham NJ
JAMA cardiology. Oct 2018
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Molecular psychiatry. Oct 2018
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Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study.
De Silva NMG, Borges MC, Hingorani A, Engmann J, Shah T, Zhang X, Luan J, Langenberg C, Wong A, Kuh D, Chambers JC, Zhang W, Järvelin MR, Sebert S, Auvinen J, Gaunt TR, Lawlor DA
Diabetes. Oct 2018
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Human Molecular Genetics. Sep 2018
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Nature genetics. Aug 2018
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American journal of human genetics. Jul 2018
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Nature genetics. Jun 2018
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Nature genetics. Jun 2018
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American journal of human genetics. May 2018
(DOI : 10.1016/j.ajhg.2018.09.009)
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Molecular psychiatry. May 2018
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Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
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Nature genetics. Apr 2018
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Disentangling the genetics of lean mass.
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The American Journal of Clinical Nutrition. Mar 2018
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Nature genetics. Mar 2018
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Nature genetics. Mar 2018
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American Journal of Epidemiology. Feb 2018
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Nature genetics. Jan 2018
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Nature genetics. Dec 2017
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Nature genetics. Nov 2017
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Molecular psychiatry. Oct 2017
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Nature genetics. Oct 2017
(DOI : 10.1038/s41588-018-0205-x)
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PLoS genetics. Aug 2017
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Nature genetics. Aug 2017
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American journal of human genetics. Aug 2017
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Nature communications. Jul 2017
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Atherosclerosis. Jul 2017
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Prins BP, Kuchenbaecker KB, Bao Y, Smart M, Zabaneh D, Fatemifar G, Luan J, Wareham NJ, Scott RA, Perry JRB, Langenberg C, Benzeval M, Kumari M, Zeggini E
Scientific reports. May 2017
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Nature communications. Apr 2017
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Hypertension (Dallas, Tex. : 1979). Mar 2017
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PLoS Medicine. Feb 2017
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Proceedings of the National Academy of Sciences of the United States of America. Dec 2016
(DOI : 10.1073/pnas.1611243113)
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.
Tachmazidou I, Süveges D, Min JL, Ritchie GRS, Steinberg J, Walter K, Iotchkova V, Schwartzentruber J, Huang J, Memari Y, McCarthy S, Crawford AA, Bombieri C, Cocca M, Farmaki AE, Gaunt TR, Jousilahti P, Kooijman MN, Lehne B, Malerba G, Männistö S, Matchan A, Medina-Gomez C, Metrustry SJ, Nag A, Ntalla I, Paternoster L, Rayner NW, Sala C, Scott WR, Shihab HA, Southam L, St Pourcain B, Traglia M, Trajanoska K, Zaza G, Zhang W, Artigas MS, Bansal N, Benn M, Chen Z, Danecek P, Lin WY, Locke A, Luan J, Manning AK, Mulas A, Sidore C, Tybjaerg-Hansen A, Varbo A, Zoledziewska M, Finan C, Hatzikotoulas K, Hendricks AE, Kemp JP, Moayyeri A, Panoutsopoulou K, Szpak M, Wilson SG, Boehnke M, Cucca F, Di Angelantonio E, Langenberg C, Lindgren C, McCarthy MI, Morris AP, Nordestgaard BG, Scott RA, Tobin MD, Wareham NJ, SpiroMeta Consortium, GoT2D Consortium, Burton P, Chambers JC, Smith GD, Dedoussis G, Felix JF, Franco OH, Gambaro G, Gasparini P, Hammond CJ, Hofman A, Jaddoe VWV, Kleber M, Kooner JS, Perola M, Relton C, Ring SM, Rivadeneira F, Salomaa V, Spector TD, Stegle O, Toniolo D, Uitterlinden AG, arcOGEN Consortium, Understanding Society Scientific Group, UK10K Consortium, Barroso I, Greenwood CMT, Perry JRB, Walker BR, Butterworth AS, Xue Y, Durbin R, Small KS, Soranzo N, Timpson NJ, Zeggini E
American journal of human genetics. Nov 2016
(DOI : 10.1016/j.ajhg.2017.04.014)
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
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Diabetes. Oct 2016
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The lancet. Diabetes & endocrinology. Oct 2016
(DOI : 10.1016/S2213-8587(16)30396-5)
Mullin BH, Zhao JH, Brown SJ, Perry JRB, Luan J, Zheng HF, Langenberg C, Dudbridge F, Scott R, Wareham NJ, Spector TD, Richards JB, Walsh JP, Wilson SG
Human Molecular Genetics. Oct 2016
(DOI : 10.1093/hmg/ddx174)
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JAMA. Oct 2016
(DOI : 10.1001/jama.2016.14568)
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Nature genetics. Sep 2016
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PLoS Medicine. Aug 2016
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International Journal of Epidemiology. Aug 2016
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Nature genetics. Jan 2016
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Human Molecular Genetics. Oct 2015
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Science translational medicine. Sep 2015
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Nature genetics. Jul 2015
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Nature genetics. Jul 2015
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Nature communications. Jun 2015
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Nature communications. Jun 2015
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The American Journal of Clinical Nutrition. May 2015
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Nature genetics. Feb 2015
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American journal of human genetics. Feb 2014
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Nature. Nov 2013
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Nature genetics. Feb 2013
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Nature genetics. Dec 2012
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Nature genetics. Oct 2012
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Discovery and refinement of loci associated with lipid levels.
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Nature genetics. Oct 2012
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Human Molecular Genetics. Jul 2012
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European Journal of Clinical Nutrition. Jun 2012
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PLoS genetics. May 2012
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International Journal of Obesity. Mar 2012
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Nature genetics. Jan 2012
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Diabetes. Aug 2011
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Nature genetics. Jul 2011
(DOI : 10.1038/ng.2274)
Travier N, Agudo A, May AM, Gonzalez C, Luan J, Wareham NJ, Bueno-de-Mesquita HB, van den Berg SW, Slimani N, Rinaldi S, Clavel-Chapelon F, Boutron-Ruault MC, Palli D, Sieri S, Mattiello A, Tumino R, Vineis P, Norat T, Romaguera D, Rodriguez L, Sánchez MJ, Dorronsoro M, Barricarte A, Huerta JM, Key TJ, Orfanos P, Naska A, Trichopoulou A, Rohrmann S, Kaaks R, Bergmann MM, Boeing H, Hallmans G, Johansson I, Manjer J, Lindkvist B, Jakobsen MU, Overvad K, Tjonneland A, Halkjaer J, Lund E, Braaten T, Odysseos A, Riboli E, Peeters PH
Preventive Medicine . May 2011
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Proceedings of the National Academy of Sciences of the United States of America. Apr 2011
(DOI : 10.1073/pnas.1017288108)
Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
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Nature genetics. Mar 2011
(DOI : 10.1038/ng.970)
CUBN is a gene locus for albuminuria.
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Journal of the American Society of Nephrology : JASN. Mar 2011
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The American Journal of Clinical Nutrition. Feb 2011
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Nature genetics. Feb 2011
(DOI : 10.1038/ng.922)
De Silva NM, Freathy RM, Palmer TM, Donnelly LA, Luan J, Gaunt T, Langenberg C, Weedon MN, Shields B, Knight BA, Ward KJ, Sandhu MS, Harbord RM, McCarthy MI, Smith GD, Ebrahim S, Hattersley AT, Wareham NJ, Lawlor DA, Morris AD, Palmer CN, Frayling TM
Diabetes. Feb 2011
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Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
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Nature genetics. Jan 2011
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Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
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Arteriosclerosis, thrombosis, and vascular biology. Sep 2010
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Diabetes. Sep 2010
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The American Journal of Clinical Nutrition. Sep 2010
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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
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Nature. Aug 2010
(DOI : 10.1038/nature10405)
Genetic predisposition to obesity leads to increased risk of type 2 diabetes.
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Diabetologia. Jul 2010
(DOI : 10.1007/s00125-011-2044-5)
Meat consumption and prospective weight change in participants of the EPIC-PANACEA study.
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The American Journal of Clinical Nutrition. Jul 2010
(DOI : 10.3945/ajcn.2009.28713)
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The American Journal of Clinical Nutrition. Jun 2010
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PLoS genetics. May 2010
(DOI : 10.1371/journal.pgen.1001177)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
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Nature genetics. May 2010
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The Journal of clinical investigation. May 2010
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The American Journal of Clinical Nutrition. May 2010
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Nature genetics. May 2010
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Hundreds of variants clustered in genomic loci and biological pathways affect human height.
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