MRC Epidemiology Unit

 

GDF15 linked to maternal risk of nausea and vomiting during pregnancy.

Fejzo M, Rocha N, Cimino I, Lockhart SM, Petry CJ, Kay RG, Burling K, Barker P, George AL, Yasara N, Premawardhena A, Gong S, Cook E, Rimmington D, Rainbow K, Withers DJ, Cortessis V, Mullin PM, MacGibbon KW, Jin E, Kam A, Campbell A, Polasek O, Tzoneva G, Gribble FM, Yeo GSH, Lam BYH, Saudek V, Hughes IA, Ong KK, Perry JRB, Sutton Cole A, Baumgarten M, Welsh P, Sattar N, Smith GCS, Charnock-Jones DS, Coll AP, Meek CL, Mettananda S, Hayward C, Mancuso N, O'Rahilly S

Nature. Dec 2023

(DOI : 10.1038/s41586-023-06921-9)

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Associations of appetitive traits with growth velocities from infancy to childhood.

Olwi DI, Day FR, Cheng TS, Olga L, Petry CJ, Hughes IA, Smith AD, Ong KK

Scientific reports. Sep 2023

(DOI : 10.1038/s41598-023-42899-0)

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Leptin and IGF-1 in infancy are associated with variants in DHCR7 and CYP2R1 that relate with type 1 diabetes and 25OHD.

Eleftheriou A, Ong KK, Hughes IA, Petry CJ

The Journal of clinical endocrinology and metabolism. May 2023

(DOI : 10.1210/clinem/dgad263)

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Associations between breast milk intake volume, macronutrient intake, and infant growth in a longitudinal birth cohort: the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF).

Olga L, Vervoort J, van Diepen JA, Gross G, Petry CJ, Prentice PM, Chichlowski M, van Tol EA, Hughes IA, Dunger DB, Ong KK

The British journal of nutrition. Oct 2022

(DOI : 10.1017/S0007114522003178)

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Associations between maternal iron supplementation in pregnancy and offspring growth and cardiometabolic risk outcomes in infancy and childhood.

Petry CJ, Olga L, Hughes IA, Ong KK

PLoS ONE. May 2022

(DOI : 10.1371/journal.pone.0263148)

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Maternal Paracetamol Intake During Pregnancy-Impacts on Offspring Reproductive Development.

Tadokoro-Cuccaro R, Fisher BG, Thankamony A, Ong KK, Hughes IA

Frontiers in toxicology. Feb 2022

(DOI : 10.3389/ftox.2022.884704)

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Increased basal insulin sensitivity in late pregnancy in women carrying a male fetus: a cohort study.

Petry CJ, Hughes IA, Ong KK

Biology of sex differences. Feb 2022

(DOI : 10.1186/s13293-022-00429-z)

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Extensive Study of Breast Milk and Infant Growth: Protocol of the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF).

Olga L, Petry CJ, van Diepen JA, Prentice PM, Hughes IA, Vervoort J, Boekhorst J, Chichlowski M, Gross G, Dunger DB, Ong KK

Nutrients. Jul 2021

(DOI : 10.3390/nu13082879)

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Associations between Maternal Iron Supplementation in Pregnancy and Changes in Offspring Size at Birth Reflect Those of Multiple Micronutrient Supplementation.

Petry CJ, Ong KK, Hughes IA, Dunger DB

Nutrients. May 2021

(DOI : 10.3390/nu13072480)

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Anthropometry-based prediction of body composition in early infancy compared to air-displacement plethysmography.

Olga L, van Beijsterveldt IALP, Hughes IA, Dunger DB, Ong KK, Hokken-Koelega ACS, De Lucia Rolfe E

Pediatric Obesity. Apr 2021

(DOI : 10.1111/ijpo.12818)

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The High-Risk Type 1 Diabetes HLA-DR and HLA-DQ Polymorphisms Are Differentially Associated With Growth and IGF-I Levels in Infancy: The Cambridge Baby Growth Study.

Eleftheriou A, Petry CJ, Hughes IA, Ong KK, Dunger DB

Diabetes care. Nov 2020

(DOI : 10.2337/dc20-2820)

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Folic acid supplementation during pregnancy and associations with offspring size at birth and adiposity: a cohort study.

Petry CJ, Ong KK, Hughes IA, Dunger DB

BMC research notes. Nov 2020

(DOI : 10.1186/s13104-021-05575-y)

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Multiple Micronutrient Supplementation during Pregnancy and Increased Birth Weight and Skinfold Thicknesses in the Offspring: The Cambridge Baby Growth Study.

Petry CJ, Ong KK, Hughes IA, Dunger DB

Nutrients. Sep 2020

(DOI : 10.3390/nu12113466)

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Lipid ratios representing SCD1, FADS1, and FADS2 activities as candidate biomarkers of early growth and adiposity.

Olga L, van Diepen JA, Bobeldijk-Pastorova I, Gross G, Prentice PM, Snowden SG, Furse S, Kooistra T, Hughes IA, Schoemaker MH, van Tol EAF, van Duyvenvoorde W, Wielinga PY, Ong KK, Dunger DB, Kleemann R, Koulman A

EBioMedicine. Sep 2020

(DOI : 10.1016/j.ebiom.2020.103198)

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Pregnancy Serum DLK1 Concentrations Are Associated With Indices of Insulin Resistance and Secretion.

Petry CJ, Burling KA, Barker P, Hughes IA, Ong KK, Dunger DB

The Journal of clinical endocrinology and metabolism. Jul 2020

(DOI : 10.1210/clinem/dgab123)

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Which infancy growth parameters are associated with later adiposity? The Cambridge Baby Growth Study.

Ong KK, Cheng TS, Olga L, Prentice PM, Petry CJ, Hughes IA, Dunger DB

Annals of human biology. May 2020

(DOI : 10.1080/03014460.2020.1745887)

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Temporal Trends in Maternal Food Intake Frequencies and Associations with Gestational Diabetes: The Cambridge Baby Growth Study.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Nutrients. Sep 2019

(DOI : 10.3390/nu11112822)

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Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism.

Furse S, Snowden SG, Olga L, Prentice P, Ong KK, Hughes IA, Acerini CL, Dunger DB, Koulman A

Scientific reports. Jun 2019

(DOI : 10.1038/s41598-019-50693-0)

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Maternal serum concentrations of bisphenol A and propyl paraben in early pregnancy are associated with male infant genital development.

Fisher BG, Thankamony A, Mendiola J, Petry CJ, Frederiksen H, Andersson AM, Juul A, Ong KK, Dunger DB, Hughes IA, Acerini CL

Human reproduction (Oxford, England). Apr 2019

(DOI : 10.1093/humrep/deaa045)

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Temporal trends without seasonal effects on gestational diabetes incidence relate to reductions in indices of insulin secretion: the Cambridge Baby Growth Study.

Petry CJ, Fisher BG, Ong KK, Hughes IA, Acerini CL, Dunger DB

Acta diabetologica. Apr 2019

(DOI : 10.1007/s00592-019-01354-1)

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Age at Menarche and Blood Pressure in Pregnancy.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Pregnancy hypertension. Feb 2019

(DOI : 10.1016/j.preghy.2019.01.004)

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Reduced size at birth and persisting reductions in adiposity in recent, compared with earlier, cohorts of infants born to mothers with gestational diabetes mellitus.

Prentice PM, Olga L, Petry CJ, Simmons D, Murphy HR, Hughes IA, Acerini CL, Ong KK, Dunger DB

Diabetologia. Jan 2019

(DOI : 10.1007/s00125-019-4970-6)

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The influence of maternal pregnancy glucose concentrations on associations between a fetal imprinted gene allele score and offspring size at birth.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

BMC research notes. Oct 2018

(DOI : 10.1186/s13104-018-3933-1)

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Human Milk Short-Chain Fatty Acid Composition is Associated with Adiposity Outcomes in Infants.

Schoemaker MH, Acerini CL, Hughes IA, Koulman A, Ong KK, Dunger DB

The Journal of nutrition. Sep 2018

(DOI : 10.1093/jn/nxy320)

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Associations of vomiting and antiemetic use in pregnancy with levels of circulating GDF15 early in the second trimester: A nested case-control study.

Petry CJ, Ong KK, Burling KA, Barker P, Goodburn SF, Perry JRB, Acerini CL, Hughes IA, Painter RC, Afink GB, Dunger DB, O'Rahilly S

Wellcome open research. Sep 2018

(DOI : 10.12688/wellcomeopenres.14818.1)

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Associations between the maternal circulating lipid profile in pregnancy and fetal imprinted gene alleles: a cohort study.

Petry CJ, Koulman A, Lu L, Jenkins B, Furse S, Prentice P, Matthews L, Hughes IA, Acerini CL, Ong KK, Dunger DB

Reproductive biology and endocrinology : RB&E. Jun 2018

(DOI : 10.1186/s12958-018-0399-x)

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The association between age at menarche and later risk of gestational diabetes is mediated by insulin resistance.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Acta diabetologica. Mar 2018

(DOI : 10.1007/s00592-018-1162-7)

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Serum Phthalate and Triclosan Levels Have Opposing Associations With Risk Factors for Gestational Diabetes Mellitus.

Fisher BG, Frederiksen H, Andersson AM, Juul A, Thankamony A, Ong KK, Dunger DB, Hughes IA, Acerini CL

Frontiers in endocrinology. Dec 2017

(DOI : 10.3389/fendo.2018.00099)

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Vomiting in pregnancy is associated with a higher risk of low birth weight: a cohort study.

Petry CJ, Ong KK, Beardsall K, Hughes IA, Acerini CL, Dunger DB

BMC pregnancy and childbirth. Aug 2017

(DOI : 10.1186/s12884-018-1786-1)

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Associations between bacterial infections and blood pressure in pregnancy.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Dunger DB

Pregnancy hypertension. May 2017

(DOI : 10.1016/j.preghy.2017.09.004)

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Early Pregnancy-Associated Plasma Protein A Concentrations Are Associated With Third Trimester Insulin Sensitivity.

Petry CJ, Ong KK, Hughes IA, Acerini CL, Frystyk J, Dunger DB

The Journal of clinical endocrinology and metabolism. Jan 2017

(DOI : 10.1210/jc.2017-00272)

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Associations between a fetal imprinted gene allele score and late pregnancy maternal glucose concentrations.

Petry CJ, Prentice P, Hayes MG, Nodzenski M, Scholtens DM, Hughes IA, Acerini CL, Ong KK, Lowe WL, Dunger DB

Diabetes & metabolism. Nov 2016

(DOI : 10.1016/j.diabet.2017.03.002)

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The translation of lipid profiles to nutritional biomarkers in the study of infant metabolism.

Acharjee A, Prentice P, Acerini C, Smith J, Hughes IA, Ong K, Griffin JL, Dunger D, Koulman A

Metabolomics : Official journal of the Metabolomic Society. Nov 2016

(DOI : 10.1007/s11306-017-1166-2)

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Associations Between Fetal Imprinted Genes and Maternal Blood Pressure in Pregnancy.

Petry CJ, Sanz Marcos N, Pimentel G, Hayes MG, Nodzenski M, Scholtens DM, Hughes IA, Acerini CL, Ong KK, Lowe WL, Dunger DB

Hypertension (Dallas, Tex. : 1979). Aug 2016

(DOI : 10.1161/HYPERTENSIONAHA.116.08261)

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An Unbiased Lipidomics Approach Identifies Early Second Trimester Lipids Predictive of Maternal Glycemic Traits and Gestational Diabetes Mellitus.

Lu L, Koulman A, Petry CJ, Jenkins B, Matthews L, Hughes IA, Acerini CL, Ong KK, Dunger DB

Diabetes care. Apr 2016

(DOI : 10.2337/dc16-0863)

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Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants.

Fisher BG, Thankamony A, Hughes IA, Ong KK, Dunger DB, Acerini CL

Human reproduction (Oxford, England). Apr 2016

(DOI : 10.1093/humrep/dew196)

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Anogenital distance as a marker of androgen exposure in humans.

Thankamony A, Pasterski V, Ong KK, Acerini CL, Hughes IA

Andrology. Oct 2015

(DOI : 10.1111/andr.12156)

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Breast milk nutrient content and infancy growth.

Prentice P, Ong KK, Schoemaker MH, Vervoort J, Hughes IA, Acerini CL, Dunger DB

Acta paediatrica (Oslo, Norway : 1992). Aug 2015

(DOI : 10.1111/apa.13362)

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Age at Weaning and Infant Growth: Primary Analysis and Systematic Review.

Vail B, Prentice P, Dunger DB, Hughes IA, Acerini CL, Ong KK

The Journal of pediatrics. Jan 2015

(DOI : 10.1016/j.jpeds.2015.05.003)

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Postnatal penile growth concurrent with mini-puberty predicts later sex-typed play behavior: Evidence for neurobehavioral effects of the postnatal androgen surge in typically developing boys.

Pasterski V, Acerini CL, Dunger DB, Ong KK, Hughes IA, Thankamony A, Hines M

Hormones and behavior. Aug 2014

(DOI : 10.1016/j.yhbeh.2015.01.002)

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Low frequency of androgen receptor gene mutations in 46 XY DSD, and fetal growth restriction.

Lek N, Miles H, Bunch T, Pilfold-Wilkie V, Tadokoro-Cuccaro R, Davies J, Ong KK, Hughes IA

Archives of Disease in Childhood. Dec 2013

(DOI : 10.1136/archdischild-2013-305338)

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Anogenital distance and penile length in infants with hypospadias or cryptorchidism: comparison with normative data.

Thankamony A, Lek N, Carroll D, Williams M, Dunger DB, Acerini CL, Ong KK, Hughes IA

Environmental health perspectives. Jun 2013

(DOI : 10.1289/ehp.1307178)

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Ultrasound estimates of visceral and subcutaneous-abdominal adipose tissues in infancy.

De Lucia Rolfe E, Modi N, Uthaya S, Hughes IA, Dunger DB, Acerini C, Stolk RP, Ong KK

Journal of Obesity. Dec 2012

(DOI : 10.1155/2013/951954)

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Associations between paternally transmitted fetal IGF2 variants and maternal circulating glucose concentrations in pregnancy.

Petry CJ, Seear RV, Wingate DL, Manico L, Acerini CL, Ong KK, Hughes IA, Dunger DB

Diabetes. Sep 2011

(DOI : 10.2337/db11-0689)

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Maternally transmitted foetal H19 variants and associations with birth weight.

Petry CJ, Seear RV, Wingate DL, Acerini CL, Ong KK, Hughes IA, Dunger DB

Human genetics. Mar 2011

(DOI : 10.1007/s00439-011-1005-x)

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Breastfeeding and infant temperament at age three months.

Lauzon-Guillain Bd, Wijndaele K, Clark M, Acerini CL, Hughes IA, Dunger DB, Wells JC, Ong KK

PLoS ONE. Feb 2011

(DOI : 10.1371/journal.pone.0029326)

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The role of androgens in fetal growth: observational study in two genetic models of disordered androgen signalling.

Miles HL, Gidlöf S, Nordenström A, Ong KK, Hughes IA

Archives of disease in childhood. Fetal and neonatal edition. Jun 2010

(DOI : 10.1136/adc.2009.173575)

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The descriptive epidemiology of congenital and acquired cryptorchidism in a UK infant cohort.

Acerini CL, Miles HL, Dunger DB, Ong KK, Hughes IA

Archives of Disease in Childhood. Jun 2009

(DOI : 10.1136/adc.2008.150219)

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Insulin sensitivity and body composition in children with classical and nonclassical congenital adrenal hyperplasia.

Williams RM, Deeb A, Ong KK, Bich W, Murgatroyd PR, Hughes IA, Acerini CL

Clinical endocrinology. Jun 2009

(DOI : 10.1111/j.1365-2265.2009.03587.x)

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Insulin-like growth factor I concentrations in infancy predict differential gains in body length and adiposity: the Cambridge Baby Growth Study.

Ong KK, Langkamp M, Ranke MB, Whitehead K, Hughes IA, Acerini CL, Dunger DB

The American Journal of Clinical Nutrition. May 2009

(DOI : 10.3945/ajcn.2008.27408)

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Anogenital distance from birth to 2 years: a population study.

Thankamony A, Ong KK, Dunger DB, Acerini CL, Hughes IA

Environmental health perspectives. Apr 2009

(DOI : 10.1289/ehp.0900881)

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Pregnancy insulin, glucose, and BMI contribute to birth outcomes in nondiabetic mothers.

Ong KK, Diderholm B, Salzano G, Wingate D, Hughes IA, MacDougall J, Acerini CL, Dunger DB

Diabetes care. Aug 2008

(DOI : 10.2337/dc08-1111)

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