MRC Epidemiology Unit

 

Leveraging pleiotropy identifies common-variant associations with selective IgA deficiency.

Willis TW, Gkrania-Klotsas E, Wareham NJ, McKinney EF, Lyons PA, Smith KGC, Wallace C

Clinical immunology (Orlando, Fla.). Sep 2024

(DOI : 10.1016/j.clim.2024.110356)

---

Feasibility of using intermittent active monitoring of vital signs by smartphone users to predict SARS-CoV-2 PCR positivity.

Dolezalova N, Gkrania-Klotsas E, Morelli D, Moore A, Cunningham AC, Booth A, Plans D, Reed AB, Aral M, Rennie KL, Wareham NJ

Scientific reports. Jun 2023

(DOI : 10.1038/s41598-023-37301-y)

---

Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with mutations.

Rae W, Sowerby JM, Verhoeven D, Youssef M, Kotagiri P, Savinykh N, Coomber EL, Boneparth A, Chan A, Gong C, Jansen MH, du Long R, Santilli G, Simeoni I, Stephens J, Wu K, Zinicola M, Allen HL, Baxendale H, Kumararatne D, Gkrania-Klotsas E, Scheffler Mendoza SC, Yamazaki-Nakashimada MA, Ruiz LB, Rojas-Maruri CM, Lugo Reyes SO, Lyons PA, Williams AP, Hodson DJ, Bishop GA, Thrasher AJ, Thomas DC, Murphy MP, Vyse TJ, Milner JD, Kuijpers TW, Smith KGC

Science immunology. Aug 2022

(DOI : 10.1126/sciimmunol.abn3800)

---

The development, validation and application of remote blood sample collection in telehealth programmes

Koulman A, Rennie K, Parkington DA, Tyrrell CSB, Catt M, Gkrania-Klotsas E, Wareham NJ

Journal of Telemedicine and Telecare. May 2022

(DOI : 10.1177/1357633X221093434)

---

Risk factors for herpes simplex virus type-1 infection and reactivation: Cross-sectional studies among EPIC-Norfolk participants.

Forbes H, Warne B, Doelken L, Brenner N, Waterboer T, Luben R, Wareham NJ, Warren-Gash C, Gkrania-Klotsas E

PLoS ONE. Jan 2019

(DOI : 10.1371/journal.pone.0215553)

---

Seropositivity and higher immunoglobulin g antibody levels against cytomegalovirus are associated with mortality in the population-based European prospective investigation of Cancer-Norfolk cohort.

Gkrania-Klotsas E, Langenberg C, Sharp SJ, Luben R, Khaw KT, Wareham NJ

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. Feb 2013

(DOI : 10.1093/cid/cit083)

---

Higher immunoglobulin G antibody levels against cytomegalovirus are associated with incident ischemic heart disease in the population-based EPIC-Norfolk cohort.

Gkrania-Klotsas E, Langenberg C, Sharp SJ, Luben R, Khaw KT, Wareham NJ

The Journal of infectious diseases. Oct 2012

(DOI : 10.1093/infdis/jis620)

---

The association between prior infection with five serotypes of Coxsackievirus B and incident type 2 diabetes mellitus in the EPIC-Norfolk study.

Gkrania-Klotsas E, Langenberg C, Tauriainen S, Sharp SJ, Luben R, Forouhi NG, Khaw KT, Hyöty H, Wareham NJ

Diabetologia. Oct 2011

(DOI : 10.1007/s00125-011-2443-7)

---

Differential white blood cell count and type 2 diabetes: systematic review and meta-analysis of cross-sectional and prospective studies.

Gkrania-Klotsas E, Ye Zheng, Cooper AJ, Sharp SJ, Luben R, Biggs ML, Chen LK, Gokulakrishnan K, Hanefeld M, Ingelsson E, Lai WA, Lin SY, Lind L, Lohsoonthorn V, Mohan V, Muscari A, Nilsson G, Ohrvik J, Chao Qiang J, Jenny NS, Tamakoshi K, Temelkova-Kurktschiev T, Wang YY, Yajnik CS, Zoli M, Khaw KT, Forouhi NG, Wareham NJ, Langenberg C

PLoS ONE. Jun 2010

(DOI : 10.1371/journal.pone.0013405)

---