MRC Epidemiology Unit

 

Associations between Children's Genetic Susceptibility to Obesity, Infant's Appetite and Parental Feeding Practices in Toddlerhood.

Guivarch C, Charles MA, Forhan A, Ong KK, Heude B, de Lauzon-Guillain B

Nutrients. Mar 2021

(DOI : 10.3390/nu13051468)

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Association between perinatal factors, genetic susceptibility to obesity and age at adiposity rebound in children of the EDEN mother-child cohort.

Cissé AH, Lioret S, de Lauzon-Guillain B, Forhan A, Ong KK, Charles MA, Heude B

International Journal of Obesity. Jun 2020

(DOI : 10.1038/s41366-021-00847-w)

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GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI.

Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, Taal HR, Warrington NM, Lewin AM, Kaakinen M, Cousminer DL, Thiering E, Timpson NJ, Bond TA, Lowry E, Brown CD, Estivill X, Lindi V, Bradfield JP, Geller F, Speed D, Coin LJM, Loh M, Barton SJ, Beilin LJ, Bisgaard H, Bønnelykke K, Alili R, Hatoum IJ, Schramm K, Cartwright R, Charles MA, Salerno V, Clément K, Claringbould AAJ, BIOS Consortium, van Duijn CM, Moltchanova E, Eriksson JG, Elks C, Feenstra B, Flexeder C, Franks S, Frayling TM, Freathy RM, Elliott P, Widén E, Hakonarson H, Hattersley AT, Rodriguez A, Banterle M, Heinrich J, Heude B, Holloway JW, Hofman A, Hyppönen E, Inskip H, Kaplan LM, Hedman ÅK, Läärä E, Prokisch H, Grallert H, Lakka TA, Lawlor DA, Melbye M, Ahluwalia TS, Marinelli M, Millwood IY, Palmer LJ, Pennell CE, Perry JR, Ring SM, Savolainen MJ, Rivadeneira F, Standl M, Sunyer J, Tiesler CMT, Uitterlinden AG, Schierding W, O'Sullivan JM, Prokopenko I, Herzig KH, Smith GD, O'Reilly P, Felix JF, Buxton JL, Blakemore AIF, Ong KK, Jaddoe VWV, Grant SFA, Sebert S, McCarthy MI, Järvelin MR, Early Growth Genetics (EGG) Consortium

Science advances. Dec 2018

(DOI : 10.1126/sciadv.aaw3095)

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Association between genetic obesity susceptibility and mother-reported eating behaviour in children up to 5 years.

de Lauzon-Guillain B, Koudou YA, Botton J, Forhan A, Carles S, Pelloux V, Clément K, Ong KK, Charles MA, Heude B, EDEN Mother-Child Cohort Study Group

Pediatric Obesity. May 2018

(DOI : 10.1111/ijpo.12496)

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Mediation and modification of genetic susceptibility to obesity by eating behaviors.

de Lauzon-Guillain B, Clifton EA, Day FR, Clément K, Brage S, Forouhi NG, Griffin SJ, Koudou YA, Pelloux V, Wareham NJ, Charles MA, Heude B, Ong KK

The American Journal of Clinical Nutrition. Mar 2017

(DOI : 10.3945/ajcn.117.157396)

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Associations between genetic obesity susceptibility and early postnatal fat and lean mass: an individual participant meta-analysis.

Elks CE, Heude B, de Zegher F, Barton SJ, Clément K, Inskip HM, Koudou Y, Cooper C, Dunger DB, Ibáñez L, Charles MA, Ong KK

JAMA pediatrics. Oct 2014

(DOI : 10.1001/jamapediatrics.2014.1619)

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Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk.

Marquez M, Huyvaert M, Perry JR, Pearson RD, Falchi M, Morris AP, Vivequin S, Lobbens S, Yengo L, Gaget S, Pattou F, Poulain-Godefroy O, Charpentier G, Carlsson LM, Jacobson P, Sjöström L, Lantieri O, Heude B, Walley A, Balkau B, Marre M, Froguel P, Cauchi S

Diabetes. Jan 2012

(DOI : 10.2337/db11-0728)

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Ghrelin receptor gene polymorphisms and body size in children and adults.

Garcia EA, Heude B, Petry CJ, Gueorguiev M, Hassan-Smith ZK, Spanou A, Ring SM, Dunger DB, Wareham NJ, Sandhu MS, Ong KK, Korbonits M

The Journal of clinical endocrinology and metabolism. Jul 2008

(DOI : 10.1210/jc.2008-0366)

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Association analysis of the IGF1 gene with childhood growth, IGF-1 concentrations and type 1 diabetes.

Vella A, Bouatia-Naji N, Heude B, Cooper JD, Lowe CE, Petry C, Ring SM, Dunger DB, Todd JA, Ong KK

Diabetologia. Dec 2007

(DOI : 10.1007/s00125-008-0970-7)

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Study of association between common variation in the insulin-like growth factor 2 gene and indices of obesity and body size in middle-aged men and women.

Heude B, Ong KK, Luben R, Wareham NJ, Sandhu MS

The Journal of clinical endocrinology and metabolism. May 2007

(DOI : 10.1210/jc.2006-1948)

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The insulin gene variable number of tandem repeat: associations and interactions with childhood body fat mass and insulin secretion in normal children.

Heude B, Petry CJ, Pembrey M, Dunger DB, Ong KK

The Journal of clinical endocrinology and metabolism. Apr 2006

(DOI : 10.1210/jc.2005-2055)

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INS VNTR class genotype and indexes of body size and obesity: population-based studies of 7,999 middle-aged men and women.

Sandhu MS, Heude B, Young EH, Luben R, Luan J, Khaw KT, Todd J, Wareham NJ

Diabetes. Aug 2005

(DOI : 10.2337/diabetes.54.9.2812)

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