MRC Epidemiology Unit
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.
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Nature communications. Jan 2020
(DOI : 10.1038/s41467-020-19366-9)
Ehret GB, Ferreira T, Chasman DI, Jackson AU, Schmidt EM, Johnson T, Thorleifsson G, Luan J, Kanoni S, Strawbridge RJ, Shungin D, Kaakinen M, Kristiansson K, Kleber ME, Lyytikäinen LP, Eriksson N, Nolte IM, Magnusson PK, Folkersen L, Pers TH, Lataniotis L, Jansen R, Johnson AD, Kim YJ, Zhao W, Tayo BO, Bochud M, Absher D, Adair LS, Amin N, Baldassarre D, Balkau B, Bandinelli S, Barroso I, Bis JC, Bjornsdottir G, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Bornstein SR, Brown MJ, Burnier M, Chambers JC, Cheng CY, Chines PS, Collins FS, Döring A, Danesh J, de Faire U, Delgado G, Dominiczak AF, Doney ASF, Drenos F, Edkins S, Eicher JD, Enroth S, Erdmann J, Eriksson P, Esko T, Fall T, Farrall M, Felix JF, Ferrières J, Ferrucci L, Fornage M, Forrester T, Franceschini N, Franco-Cereceda A, Fraser RM, Gertow K, Gigante B, Giulianini F, Goel A, Goodall AH, Goodarzi MO, Gorski M, Gräßler J, Gudnason V, Gyllensten U, Hallmans G, Hartikainen AL, Hassinen M, Hayward C, Herzig KH, Hicks AA, Hingorani AD, Hirschhorn JN, Hofman A, Holmen OL, Hottenga JJ, Howard P, Hunt SC, Ikram MA, Illig T, Jensen RA, Kähönen M, Kathiresan S, Keating BJ, Khaw KT, Kim YK, Kivimaki M, Klopp N, Kooner JS, Krauss RM, Kutalik Z, Kuusisto J, Lakka TA, Lee NR, Lee IT, Lee WJ, Levy D, Lindström J, Lobbens S, Männistö S, Müller G, Müller-Nurasyid M, Mach F, Marouli E, McCarthy MI, McKenzie CA, Menni C, Metspalu A, Montasser ME, Morris AD, Morrison AC, Mulas A, Nagaraja R, Narisu N, Nikus K, O'Donnell CJ, Ong KK, Palmer CD, Pedersen NL, Penninx BW, Perola M, Peters A, Poulter N, Pramstaller PP, Psaty BM, Quertermous T, Rao DC, Rasheed A, Renstrom F, Rettig R, Rice KM, Roberts R, Rose LM, Samani NJ, Sanna S, Saramies J, Schunkert H, Sebert S, Sheu WH, Smit JH, Smith AV, Spector TD, Stančáková A, Stringham HM, Sundström J, Swift AJ, Syvänen AC, Tai ES, Tanaka T, Teumer A, Thorsteinsdottir U, Tobin MD, Tremoli E, Uitterlinden AG, Uusitupa M, Vaez A, Vaidya D, van Duijn CM, Virtamo J, Vitart V, Voight BF, Vollenweider P, Wain LV, Wareham NJ, Watkins H, Westra HJ, Wilsgaard T, Wilson JF, Wong TY, Yengo L, Zhang W, Zhao JH, Bovet P, Cooper RS, Mohlke KL, Saleheen D, Lee JY, Elliott P, Willer CJ, Franke L, Hovingh GK, Taylor KD, Dedoussis G, Sever P, Wong A, Lind L, Assimes TL, Njølstad I, Schwarz PE, Langenberg C, Snieder H, Caulfield MJ, Melander O, Laakso M, Saltevo J, Rauramaa R, Tuomilehto J, Ingelsson E, Lehtimäki T, Hveem K, März W, Kumari M, Salomaa V, Chen YI, Rotter JI, Froguel P, Järvelin MR, Kuulasmaa K, Franks PW, Hamsten A, Wichmann HE, Palmer CNA, Stefansson K, Ridker PM, Loos RJF, Chakravarti A, Deloukas P, Morris AP, Munroe PB
Nature genetics. Jul 2015
(DOI : 10.1038/ng.3667)
Holmes MV, Exeter HJ, Folkersen L, Nelson CP, Guardiola M, Cooper JA, Sofat R, Boekholdt SM, Khaw KT, Li KW, Smith AJ, Van't Hooft F, Eriksson P, Franco-Cereceda A, Asselbergs FW, Boer JM, Onland-Moret NC, Hofker M, Erdmann J, Kivimaki M, Kumari M, Reiner AP, Keating BJ, Humphries SE, Hingorani AD, Mallat Z, Samani NJ, Talmud PJ, CARDIoGRAM Consortium
Circulation. Cardiovascular genetics. Feb 2014
(DOI : 10.1161/CIRCGENETICS.113.000271)
New genetic loci link adipose and insulin biology to body fat distribution.
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Nature. Nov 2013
(DOI : 10.1038/nature14132)
Genetic studies of body mass index yield new insights for obesity biology.
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stančáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, Van Der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S, 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Nature. Nov 2013
(DOI : 10.1038/nature14177)
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.
Holmes MV, Simon T, Exeter HJ, Folkersen L, Asselbergs FW, Guardiola M, Cooper JA, Palmen J, Hubacek JA, Carruthers KF, Horne BD, Brunisholz KD, Mega JL, van Iperen EPA, Li M, Leusink M, Trompet S, Verschuren JJW, Hovingh GK, Dehghan A, Nelson CP, Kotti S, Danchin N, Scholz M, Haase CL, Rothenbacher D, Swerdlow DI, Kuchenbaecker KB, Staines-Urias E, Goel A, van 't Hooft F, Gertow K, de Faire U, Panayiotou AG, Tremoli E, Baldassarre D, Veglia F, Holdt LM, Beutner F, Gansevoort RT, Navis GJ, Mateo Leach I, Breitling LP, Brenner H, Thiery J, Dallmeier D, Franco-Cereceda A, Boer JMA, Stephens JW, Hofker MH, Tedgui A, Hofman A, Uitterlinden AG, Adamkova V, Pitha J, Onland-Moret NC, Cramer MJ, Nathoe HM, Spiering W, Klungel OH, Kumari M, Whincup PH, Morrow DA, Braund PS, Hall AS, Olsson AG, Doevendans PA, Trip MD, Tobin MD, Hamsten A, Watkins H, Koenig W, Nicolaides AN, Teupser D, Day INM, Carlquist JF, Gaunt TR, Ford I, Sattar N, Tsimikas S, Schwartz GG, Lawlor DA, Morris RW, Sandhu MS, Poledne R, Maitland-van der Zee AH, Khaw KT, Keating BJ, van der Harst P, Price JF, Mehta SR, Yusuf S, Witteman JCM, Franco OH, Jukema JW, de Knijff P, Tybjaerg-Hansen A, Rader DJ, Farrall M, Samani NJ, Kivimaki M, Fox KAA, Humphries SE, Anderson JL, Boekholdt SM, Palmer TM, Eriksson P, Pare G, Hingorani AD, Sabatine MS, Mallat Z, Casas JP, Talmud PJ
Journal of the American College of Cardiology. Apr 2013
(DOI : 10.1016/j.jacc.2013.06.044)
A gene-centric study of common carotid artery remodelling.
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