MRC Epidemiology Unit

 

A randomised trial of the effect and cost-effectiveness of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with screen-detected type 2 diabetes: the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (ADDITION-Europe) study.

Simmons RK, Borch-Johnsen K, Lauritzen T, Rutten GE, Sandbæk A, van den Donk M, Black JA, Tao L, Wilson EC, Davies MJ, Khunti K, Sharp SJ, Wareham NJ, Griffin SJ

Health technology assessment (Winchester, England). Sep 2016

(DOI : 10.3310/hta20640)

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Cardiovascular risk factors and incident albuminuria in screen-detected type 2 diabetes.

Webb DR, Zaccardi F, Davies MJ, Griffin SJ, Wareham NJ, Simmons RK, Rutten GE, Sandbaek A, Lauritzen T, Borch-Johnsen K, Khunti K

Diabetes/metabolism research and reviews. Aug 2016

(DOI : 10.1002/dmrr.2877)

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Cost-effectiveness of intensive multifactorial treatment compared with routine care for individuals with screen-detected Type 2 diabetes: analysis of the ADDITION-UK cluster-randomized controlled trial.

Tao L, Wilson EC, Wareham NJ, Sandbaek A, Rutten GE, Lauritzen T, Khunti K, Davies MJ, Borch-Johnsen K, Griffin SJ, Simmons RK

Diabetic medicine : a journal of the British Diabetic Association. Feb 2015

(DOI : 10.1111/dme.12711)

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Early Detection and Treatment of Type 2 Diabetes Reduce Cardiovascular Morbidity and Mortality: A Simulation of the Results of the Anglo-Danish-Dutch Study of Intensive Treatment in People With Screen-Detected Diabetes in Primary Care (ADDITION-Europe).

Herman WH, Ye W, Griffin SJ, Simmons RK, Davies MJ, Khunti K, Rutten GE, Sandbaek A, Lauritzen T, Borch-Johnsen K, Brown MB, Wareham NJ

Diabetes care. Oct 2014

(DOI : 10.2337/dc14-2459)

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Effect of early multifactorial therapy compared with routine care on microvascular outcomes at 5 years in people with screen-detected diabetes: a randomized controlled trial: the ADDITION-Europe Study.

Sandbæk A, Griffin SJ, Sharp SJ, Simmons RK, Borch-Johnsen K, Rutten GE, van den Donk M, Wareham NJ, Lauritzen T, Davies MJ, Khunti K

Diabetes care. May 2014

(DOI : 10.2337/dc13-1544)

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Change in cardiovascular risk factors following early diagnosis of type 2 diabetes: a cohort analysis of a cluster-randomised trial.

Black JA, Sharp SJ, Wareham NJ, Sandbæk A, Rutten GE, Lauritzen T, Khunti K, Davies MJ, Borch-Johnsen K, Griffin SJ, Simmons RK

The British journal of general practice : the journal of the Royal College of General Practitioners. Apr 2014

(DOI : 10.3399/bjgp14X677833)

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Does early intensive multifactorial therapy reduce modelled cardiovascular risk in individuals with screen-detected diabetes? Results from the ADDITION-Europe cluster randomized trial.

Black JA, Sharp SJ, Wareham NJ, Sandbaek A, Rutten GE, Lauritzen T, Khunti K, Davies MJ, Borch-Johnsen K, Griffin SJ, Simmons RK

Diabetic medicine : a journal of the British Diabetic Association. Sep 2013

(DOI : 10.1111/dme.12410)

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Diabetes-specific quality of life but not health status is independently associated with glycaemic control among patients with type 2 diabetes: a cross-sectional analysis of the ADDITION-Europe trial cohort.

Kuznetsov L, Griffin SJ, Davies MJ, Lauritzen T, Khunti K, Rutten GE, Simmons RK

Diabetes Research and Clinical Practice. Jun 2013

(DOI : 10.1016/j.diabres.2013.12.029)

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Effect of early intensive multifactorial therapy compared with routine care on self-reported health status, general well-being, diabetes-specific quality of life and treatment satisfaction in screen-detected type 2 diabetes mellitus patients (ADDITION-Europe): a cluster-randomised trial.

van den Donk M, Griffin SJ, Stellato RK, Simmons RK, Sandbæk A, Lauritzen T, Khunti K, Davies MJ, Borch-Johnsen K, Wareham NJ, Rutten GE

Diabetologia. Apr 2013

(DOI : 10.1007/s00125-013-3011-0)

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Does early intensive multifactorial treatment reduce total cardiovascular burden in individuals with screen-detected diabetes? Findings from the ADDITION-Europe cluster-randomized trial.

Simmons RK, Sharp SJ, Sandbæk A, Borch-Johnsen K, Davies MJ, Khunti K, Lauritzen T, Rutten GE, van den Donk M, Wareham NJ, Griffin SJ

Diabetic medicine : a journal of the British Diabetic Association. Jul 2012

(DOI : 10.1111/j.1464-5491.2012.03759.x)

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Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial.

Griffin SJ, Borch-Johnsen K, Davies MJ, Khunti K, Rutten GE, Sandbæk A, Sharp SJ, Simmons RK, van den Donk M, Wareham NJ, Lauritzen T

Lancet (London, England). Jun 2011

(DOI : 10.1016/S0140-6736(11)60698-3)

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Screening for type 2 diabetes. Lessons from the ADDITION-Europe study.

van den Donk M, Sandbaek A, Borch-Johnsen K, Lauritzen T, Simmons RK, Wareham NJ, Griffin SJ, Davies MJ, Khunti K, Rutten GE

Diabetic medicine : a journal of the British Diabetic Association. Jun 2011

(DOI : 10.1111/j.1464-5491.2011.03365.x)

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