MRC Epidemiology Unit
Understanding the genetic complexity of puberty timing across the allele frequency spectrum.
Kentistou KA, Kaisinger LR, Stankovic S, Vaudel M, Mendes de Oliveira E, Messina A, Walters RG, Liu X, Busch AS, Helgason H, Thompson DJ, Santoni F, Petricek KM, Zouaghi Y, Huang-Doran I, Gudbjartsson DF, Bratland E, Lin K, Gardner EJ, Zhao Y, Jia RY, Terao C, Riggan MJ, Bolla MK, Yazdanpanah M, Yazdanpanah N, Bradfield JP, Broer L, Campbell A, Chasman DI, Cousminer DL, Franceschini N, Franke LH, Girotto G, He C, Järvelin MR, Joshi PK, Kamatani Y, Karlsson R, Luan J, Lunetta KL, Mägi R, Mangino M, Medland SE, Meisinger C, Noordam R, Nutile T, Concas MP, Polasek O, Porcu E, Ring SM, Sala C, Smith AV, Tanaka T, van der Most PJ, Vitart V, Wang CA, Willemsen G, Zygmunt M, Ahearn TU, Andrulis IL, Anton-Culver H, Antoniou AC, Auer PL, Barnes CLK, Beckmann MW, Berrington de González A, Bogdanova NV, Bojesen SE, Brenner H, Buring JE, Canzian F, Chang-Claude J, Couch FJ, Cox A, Crisponi L, Czene K, Daly MB, Demerath EW, Dennis J, Devilee P, De Vivo I, Dörk T, Dunning AM, Dwek M, Eriksson JG, Fasching PA, Fernández-Rhodes L, Ferreli L, Fletcher O, Gago-Dominguez M, García-Closas M, García-Sáenz JA, González-Neira A, Grallert H, Guénel P, Haiman CA, Hall P, Hamann U, Hakonarson H, Hart RJ, Hickey M, Hooning MJ, Hoppe R, Hopper JL, Hottenga JJ, Hu FB, Huebner H, Hunter DJ, ABCTB Investigators ABCTB Investigators, Jernström H, John EM, Karasik D, Khusnutdinova EK, Kristensen VN, Lacey JV, Lambrechts D, Launer LJ, Lind PA, Lindblom A, Magnusson PKE, Mannermaa A, McCarthy MI, Meitinger T, Menni C, Michailidou K, Millwood IY, Milne RL, Montgomery GW, Nevanlinna H, Nolte IM, Nyholt DR, Obi N, O'Brien KM, Offit K, Oldehinkel AJ, Ostrowski SR, Palotie A, Pedersen OB, Peters A, Pianigiani G, Plaseska-Karanfilska D, Pouta A, Pozarickij A, Radice P, Rennert G, Rosendaal FR, Ruggiero D, Saloustros E, Sandler DP, Schipf S, Schmidt CO, Schmidt MK, Small K, Spedicati B, Stampfer M, Stone J, Tamimi RM, Teras LR, Tikkanen E, Turman C, Vachon CM, Wang Q, Winqvist R, Wolk A, Zemel BS, Zheng W, van Dijk KW, Alizadeh BZ, Bandinelli S, Boerwinkle E, Boomsma DI, Ciullo M, Chenevix-Trench G, Cucca F, Esko T, Gieger C, Grant SFA, Gudnason V, Hayward C, Kolcic I, Kraft P, Lawlor DA, Martin NG, Nøhr EA, Pedersen NL, Pennell CE, Ridker PM, Robino A, Snieder H, Sovio U, Spector TD, Stöckl D, Sudlow C, Timpson NJ, Toniolo D, Uitterlinden A, Ulivi S, Völzke H, Wareham NJ, Widén E, Wilson JF, Lifelines Cohort Study Lifelines Cohort Study, Danish Blood Donor Study Danish Blood Donor Study, Ovarian Cancer Association Consortium Ovarian Cancer Association Consortium, Breast Cancer Association Consortium Breast Cancer Association Consortium, Biobank Japan Project Biobank Japan Project, China Kadoorie Biobank Collaborative Group China Kadoorie Biobank Collaborative Group, Pharoah PDP, Li L, Easton DF, Njølstad PR, Sulem P, Murabito JM, Murray A, Manousaki D, Juul A, Erikstrup C, Stefansson K, Horikoshi M, Chen Z, Farooqi IS, Pitteloud N, Johansson S, Day FR, Perry JRB, Ong KK
Nature genetics. Jul 2024
(DOI : 10.1038/s41588-024-01798-4)
Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, Chasman DI, Morris AP, Caulfield MJ, Hwang SJ, Kooner JS, Conen D, Attia JR, Morrison AC, Loos RJF, Kristiansson K, Schmidt R, Hicks AA, Pramstaller PP, Nelson CP, Samani NJ, Risch L, Gyllensten U, Melander O, Riese H, Wilson JF, Campbell H, Rich SS, Psaty BM, Lu Y, Rotter JI, Guo X, Rice KM, Vollenweider P, Sundström J, Langenberg C, Tobin MD, Giedraitis V, Luan J, Tuomilehto J, Kutalik Z, Ripatti S, Salomaa V, Girotto G, Trompet S, Jukema JW, van der Harst P, Ridker PM, Giulianini F, Vitart V, Goel A, Watkins H, Harris SE, Deary IJ, van der Most PJ, Oldehinkel AJ, Keavney BD, Hayward C, Campbell A, Boehnke M, Scott LJ, Boutin T, Mamasoula C, Järvelin MR, Peters A, Gieger C, Lakatta EG, Cucca F, Hui J, Knekt P, Enroth S, de Borst MH, Polasek O, Concas MP, Catamo E, Cocca M, Li-Gao R, Hofer E, Schmidt H, Spedicati B, Waldenberger M, Strachan DP, Laan M, Teumer A, Dörr M, Gudnason V, Cook JP, Ruggiero D, Kolcic I, Boerwinkle E, Traglia M, Lehtimäki T, Raitakari OT, Johnson AD, Newton-Cheh C, Brown MJ, Dominiczak AF, Sever PJ, Poulter N, Chambers JC, Elosua R, Siscovick D, Esko T, Metspalu A, Strawbridge RJ, Laakso M, Hamsten A, Hottenga JJ, de Geus E, Morris AD, Palmer CNA, Nolte IM, Milaneschi Y, Marten J, Wright A, Zeggini E, Howson JMM, O'Donnell CJ, Spector T, Nalls MA, Simonsick EM, Liu Y, van Duijn CM, Butterworth AS, Danesh JN, Menni C, Wareham NJ, Khaw KT, Sun YV, Wilson PWF, Cho K, Visscher PM, Denny JC, Million Veteran Program Million Veteran Program, Lifelines Cohort Study Lifelines Cohort Study, CHARGE consortium CHARGE consortium, ICBP Consortium ICBP Consortium, Levy D, Edwards TL, Munroe PB, Snieder H, Warren HR
Nature genetics. Apr 2024
(DOI : 10.1038/s41588-024-01714-w)
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.
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Nature. Feb 2024
(DOI : 10.1038/s41586-024-07019-6)
Genetic insights into resting heart rate and its role in cardiovascular disease.
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Nature communications. Aug 2023
(DOI : 10.1038/s41467-023-39521-2)
Circulating metabolites modulated by diet are associated with depression.
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Molecular psychiatry. Jul 2023
(DOI : 10.1038/s41380-023-02180-2)
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Nature genetics. Jun 2023
(DOI : 10.1038/s41588-023-01408-9)
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Nature genetics. Mar 2023
(DOI : 10.1038/s41588-023-01314-0)
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Nature Human Behaviour. Mar 2023
(DOI : 10.1038/s41562-023-01528-6)
Loci for insulin processing and secretion provide insight into type 2 diabetes risk.
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American journal of human genetics. Jan 2023
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Nature. Sep 2020
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Nature. Aug 2020
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The American Journal of Clinical Nutrition. Mar 2018
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Nature genetics. Mar 2018
(DOI : 10.1038/s41588-018-0050-y)
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Nature genetics. Mar 2018
(DOI : 10.1038/s41588-018-0082-3)
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PLoS ONE. Feb 2018
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American Journal of Epidemiology. Feb 2018
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Nature genetics. Jan 2018
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Nature genetics. Dec 2017
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American journal of human genetics. Oct 2017
(DOI : 10.1016/j.ajhg.2018.01.015)
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Nature genetics. Oct 2017
(DOI : 10.1038/s41588-018-0205-x)
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PLoS genetics. Aug 2017
(DOI : 10.1371/journal.pgen.1006972)
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Nature genetics. Aug 2017
(DOI : 10.1038/s41588-017-0011-x)
Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
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Scientific data. May 2017
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Nature genetics. May 2017
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Hypertension (Dallas, Tex. : 1979). Mar 2017
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PLoS Medicine. Feb 2017
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Nature genetics. Jan 2017
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Genome biology. Oct 2016
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Nature genetics. Sep 2016
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Human Molecular Genetics. Dec 2015
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Science translational medicine. Sep 2015
(DOI : 10.1126/scitranslmed.aad3744)
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
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Nature communications. Aug 2015
(DOI : 10.1038/s41467-017-00031-7)
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.
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Human Molecular Genetics. Jul 2015
(DOI : 10.1093/hmg/ddv454)
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Nature genetics. Jul 2015
(DOI : 10.1038/ng.3667)
Association of Cardiometabolic Multimorbidity With Mortality.
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JAMA. Jul 2015
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Nature communications. Jun 2015
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Nature communications. Jun 2015
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The genetic architecture of type 2 diabetes.
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Nature. May 2015
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The New England journal of medicine. Apr 2015
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Nature genetics. Dec 2013
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Nature. Nov 2013
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Nature genetics. Oct 2012
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Genome-wide meta-analysis of common variant differences between men and women.
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Human Molecular Genetics. Jul 2012
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PLoS genetics. May 2012
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Nature genetics. Jan 2012
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Nature genetics. Jan 2012
(DOI : 10.1038/ng.2383)
FTO genotype is associated with phenotypic variability of body mass index.
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Nature. Jan 2012
(DOI : 10.1038/nature11401)
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
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Nature genetics. Aug 2010
(DOI : 10.1038/ng.784)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
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Nature genetics. May 2010
(DOI : 10.1038/ng.686)
