MRC Epidemiology Unit

 

Genetic predisposition to an adverse lipid profile limits the improvement in total cholesterol in response to weight loss.

Walker CG, Holzapfel C, Loos RJ, Mander AP, Klopp N, Illig T, Caterson ID, Hauner H, Jebb SA

Obesity (Silver Spring, Md.). Aug 2012

(DOI : 10.1002/oby.20328)

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Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat.

Walker CG, Loos RJ, Mander AP, Jebb SA, Frost GS, Griffin BA, Lovegrove JA, Sanders TA, Bluck LJ

Genes & nutrition. Nov 2011

(DOI : 10.1007/s12263-012-0284-8)

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Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids.

Walker CG, Loos RJ, Olson AD, Frost GS, Griffin BA, Lovegrove JA, Sanders TA, Jebb SA

Atherosclerosis. Oct 2010

(DOI : 10.1016/j.atherosclerosis.2010.12.039)

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