MRC Epidemiology Unit

 

Impact on offspring methylation patterns of maternal gestational diabetes mellitus and intrauterine growth restraint suggest common genes and pathways linked to subsequent type 2 diabetes risk.

Quilter CR, Cooper WN, Cliffe KM, Skinner BM, Prentice PM, Nelson L, Bauer J, Ong KK, Constância M, Lowe WL, Affara NA, Dunger DB

FASEB journal : official publication of the Federation of American Societies for Experimental Biology. Aug 2014

(DOI : 10.1096/fj.14-255240)

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DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial.

Cooper WN, Khulan B, Owens S, Elks CE, Seidel V, Prentice AM, Belteki G, Ong KK, Affara NA, Constância M, Dunger DB

FASEB journal : official publication of the Federation of American Societies for Experimental Biology. Jan 2012

(DOI : 10.1096/fj.11-192708)

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Child health, developmental plasticity, and epigenetic programming.

Hochberg Z, Feil R, Constância M, Fraga M, Junien C, Carel JC, Boileau P, Le Bouc Y, Deal CL, Lillycrop K, Scharfmann R, Sheppard A, Skinner M, Szyf M, Waterland RA, Waxman DJ, Whitelaw E, Ong K, Albertsson-Wikland K

Endocrine reviews. Oct 2010

(DOI : 10.1210/er.2009-0039)

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Increased placental glucose transport rates in pregnant mice carrying fetuses with targeted disruption of their placental-specific Igf2 transcripts are not associated with raised circulating glucose concentrations.

Petry CJ, Evans ML, Wingate DL, Ong KK, Reik W, Constância M, Dunger DB

Experimental diabetes research. Sep 2010

(DOI : 10.1155/2011/171376)

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Raised late pregnancy glucose concentrations in mice carrying pups with targeted disruption of H19delta13.

Petry CJ, Evans ML, Wingate DL, Ong KK, Reik W, Constância M, Dunger DB

Diabetes. Oct 2009

(DOI : 10.2337/db09-0757)

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