MRC Epidemiology Unit

 

Dietary, lifestyle and clinicopathological factors associated with APC mutations and promoter methylation in colorectal cancers from the EPIC-Norfolk study.

Gay LJ, Mitrou PN, Keen J, Bowman R, Naguib A, Cooke J, Kuhnle GG, Burns PA, Luben R, Lentjes M, Khaw KT, Ball RY, Ibrahim AE, Arends MJ

The Journal of pathology. May 2012

(DOI : 10.1002/path.4085)

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MLH1 promoter methylation, diet, and lifestyle factors in mismatch repair deficient colorectal cancer patients from EPIC-Norfolk.

Gay LJ, Arends MJ, Mitrou PN, Bowman R, Ibrahim AE, Happerfield L, Luben R, McTaggart A, Ball RY, Rodwell SA

Nutrition and cancer. Aug 2011

(DOI : 10.1080/01635581.2011.596987)

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A single nucleotide polymorphism in the 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene ( HMGCR) influences the serum triacylglycerol relationship with dietary fat and fibre in the European Prospective Investigation into Cancer and Nutrition in Norfolk (EPIC-Norfolk) study.

Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, Bingham SA

The British journal of nutrition. Jun 2010

(DOI : 10.1017/S0007114510001145)

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HMGCR gene polymorphism is associated with stroke risk in the EPIC-Norfolk study.

Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, Rodwell S

European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. Nov 2009

(DOI : 10.1097/HJR.0b013e328330be77)

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MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study.

Loh YH, Mitrou PN, Bowman R, Wood A, Jeffery H, Luben RN, Lentjes MA, Khaw KT, Rodwell SA

DNA repair. Sep 2009

(DOI : 10.1016/j.dnarep.2010.01.002)

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APOE genotype, lipids, and coronary heart disease risk: a prospective population study.

Ward H, Mitrou PN, Bowman R, Luben R, Wareham NJ, Khaw KT, Bingham S

Archives of internal medicine. Aug 2009

(DOI : 10.1001/archinternmed.2009.234)

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A HMGCR polymorphism is associated with relations between blood pressure and urinary sodium and potassium ratio in the Epic-Norfolk Study.

Freitas RN, Khaw KT, Wu K, Bowman R, Jeffery H, Luben R, Wareham NJ, Bingham SA

Journal of the American Society of Hypertension : JASH. Mar 2009

(DOI : 10.1016/j.jash.2009.05.001)

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No association between APOE and major depressive disorder in a community sample of 17,507 adults.

Surtees PG, Wainwright NW, Bowman R, Luben RN, Wareham NJ, Khaw KT, Bingham SA

Journal of psychiatric research. Aug 2008

(DOI : 10.1016/j.jpsychires.2008.12.001)

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Blood pressure and interactions between the angiotensin polymorphism AGT M235T and sodium intake: a cross-sectional population study.

Norat T, Bowman R, Luben R, Welch A, Khaw KT, Wareham NJ, Bingham S

The American Journal of Clinical Nutrition. Aug 2008

(DOI : 10.1093/ajcn/88.2.392)

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Factor VII, blood lipids and fat intake: gene-nutrient interaction and risk of coronary heart disease with the factor VII R353Q polymorphism.

Bowman R, Joosen AM, Welch AA, Luben RN, Khaw KT, Wareham NJ, Bingham SA

European Journal of Clinical Nutrition. Apr 2008

(DOI : 10.1038/ejcn.2008.28)

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Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study.

Wu K, Bowman R, Welch AA, Luben RN, Wareham NJ, Khaw KT, Bingham SA

European heart journal. Nov 2007

(DOI : 10.1093/eurheartj/ehm482)

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Genome-wide association study identifies novel breast cancer susceptibility loci.

Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R, Wareham NJ, Ahmed S, Healey CS, Bowman R, Meyer KB, Haiman CA, Kolonel LK, Henderson BE, Le Marchand L, Brennan P, Sangrajrang S, Gaborieau V, Odefrey F, Shen CY, Wu PE, Wang HC, Eccles D, Evans DG, Peto J, Fletcher O, Johnson N, Seal S, Stratton MR, Rahman N, Chenevix-Trench G, Bojesen SE, Nordestgaard BG, Axelsson CK, García-Closas M, Brinton L, Chanock S, Lissowska J, Peplonska B, Nevanlinna H, Fagerholm R, Eerola H, Kang D, Yoo KY, Noh DY, Ahn SH, Hunter DJ, Hankinson SE, Cox DG, Hall P, Wedren S, Liu J, Low YL, Bogdanova N, Schürmann P, Dörk T, Tollenaar RA, Jacobi CE, Devilee P, Klijn JG, Sigurdson AJ, Doody MM, Alexander BH, Zhang J, Cox A, Brock IW, MacPherson G, Reed MW, Couch FJ, Goode EL, Olson JE, Meijers-Heijboer H, van den Ouweland A, Uitterlinden A, Rivadeneira F, Milne RL, Ribas G, González-Neira A, Benitez J, Hopper JL, McCredie M, Southey M, Giles GG, Schroen C, Justenhoven C, Brauch H, Hamann U, Ko YD, Spurdle AB, Beesley J, Chen X, Mannermaa A, Kosma VM, Kataja V, Hartikainen J, Day NE, Cox DR, Ponder BA

Nature. Feb 2007

(DOI : 10.1038/nature05887)

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