MRC Epidemiology Unit

 

A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemia.

Dash S, Sano H, Rochford JJ, Semple RK, Yeo G, Hyden CS, Soos MA, Clark J, Rodin A, Langenberg C, Druet C, Fawcett KA, Tung YC, Wareham NJ, Barroso I, Lienhard GE, O'Rahilly S, Savage DB

Proceedings of the National Academy of Sciences of the United States of America. May 2009

(DOI : 10.1073/pnas.0900909106)

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Analysis of genetic variation in Akt2/PKB-beta in severe insulin resistance, lipodystrophy, type 2 diabetes, and related metabolic phenotypes.

Tan K, Kimber WA, Luan J, Soos MA, Semple RK, Wareham NJ, O'Rahilly S, Barroso I

Diabetes. Mar 2007

(DOI : 10.2337/db06-0921)

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Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies.

Semple RK, Halberg NH, Burling K, Soos MA, Schraw T, Luan J, Cochran EK, Dunger DB, Wareham NJ, Scherer PE, Gorden P, O'Rahilly S

Diabetes. Feb 2007

(DOI : 10.2337/db06-1665)

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Elevated plasma adiponectin in humans with genetically defective insulin receptors.

Semple RK, Soos MA, Luan J, Mitchell CS, Wilson JC, Gurnell M, Cochran EK, Gorden P, Chatterjee VK, Wareham NJ, O'Rahilly S

The Journal of clinical endocrinology and metabolism. May 2006

(DOI : 10.1210/jc.2006-0166)

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