MRC Epidemiology Unit

 

Physical activity volume, intensity, and mortality: Harmonized meta-analysis of prospective cohort studies.

Tarp J, Dalene KE, Fagerland MW, Steene-Johannesen J, Hansen BH, Anderssen SA, Hagströmer M, Dohrn IM, Dempsey PC, Wijndaele K, Brage S, Nordström A, Nordström P, Diaz KM, Howard VJ, Hooker SP, Morseth B, Hopstock LA, Sagelv EH, Yates T, Edwardson CL, Lee IM, Ekelund U

American Journal of Preventive Medicine. Aug 2024

(DOI : 10.1016/j.amepre.2024.07.022)

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Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies.

Garcia L, Pearce M, Abbas A, Mok A, Strain T, Ali S, Crippa A, Dempsey PC, Golubic R, Kelly P, Laird Y, McNamara E, Moore S, de Sá TH, Smith AD, Wijndaele K, Woodcock J, Brage S

British Journal of Sports Medicine. Feb 2023

(DOI : 10.1136/bjsports-2022-105669)

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Reducing Sitting Time in Type 1 Diabetes: Considerations and Implications.

Alobaid AM, Dempsey PC, Francois M, Zulyniak MA, Hopkins M, Campbell MD

Canadian journal of diabetes. Feb 2023

(DOI : 10.1016/j.jcjd.2023.02.003)

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Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults.

Strain T, Dempsey PC, Wijndaele K, Sharp SJ, Kerrison N, Gonzales TI, Li C, Wheeler E, Langenberg C, Brage S, Wareham N

Diabetes care. Jan 2023

(DOI : 10.2337/dc22-1467)

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Stepping towards More Intuitive Physical Activity Metrics with Wrist-Worn Accelerometry: Validity of an Open-Source Step-Count Algorithm.

Maylor BD, Edwardson CL, Dempsey PC, Patterson MR, Plekhanova T, Yates T, Rowlands AV

Sensors (Basel, Switzerland). Dec 2022

(DOI : 10.3390/s22249984)

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Bidirectional associations of accelerometer-assessed physical activity and sedentary time with physical function among older English adults: the EPIC-Norfolk cohort study.

Yerrakalva D, Hajna S, Wijndaele K, Dempsey PC, Westgate K, Wareham N, Griffin SJ, Brage S

European journal of ageing. Dec 2022

(DOI : 10.1007/s10433-022-00733-y)

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Stepping up with GGIR: Validity of step cadence derived from wrist-worn research-grade accelerometers using the verisense step count algorithm.

Rowlands AV, Maylor B, Dawkins NP, Dempsey PC, Edwardson CL, Soczawa-Stronczyk AA, Bocian M, Patterson MR, Yates T

Journal of sports sciences. Nov 2022

(DOI : 10.1080/02640414.2022.2147134)

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Physical Activity Volume, Intensity and Incident Cardiovascular Disease.

Dempsey PC, Rowlands AV, Strain T, Zaccardi F, Dawkins N, Razieh C, Davies MJ, Khunti KK, Edwardson CL, Wijndaele K, Brage S, Yates T

European heart journal. Oct 2022

(DOI : 10.1093/eurheartj/ehac613)

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Association of Accelerometer-Measured Sedentary Accumulation Patterns With Incident Cardiovascular Disease, Cancer, and All-Cause Mortality.

Dempsey PC, Strain T, Winkler EAH, Westgate K, Rennie KL, Wareham NJ, Brage S, Wijndaele K

Journal of the American Heart Association. Apr 2022

(DOI : 10.1161/JAHA.121.023845)

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Investigation of a UK biobank cohort reveals causal associations of self-reported walking pace with telomere length.

Dempsey PC, Musicha C, Rowlands AV, Davies M, Khunti K, Razieh C, Timmins I, Zaccardi F, Codd V, Nelson CP, Yates T, Samani NJ

Communications biology. Apr 2022

(DOI : 10.1038/s42003-022-03323-x)

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Device-measured physical activity, adiposity and mortality: a harmonised meta-analysis of eight prospective cohort studies.

Tarp J, Fagerland MW, Dalene KE, Johannessen JS, Hansen BH, Jefferis BJ, Whincup PH, Diaz KM, Hooker S, Howard VJ, Chernofsky A, Larson MG, Spartano NL, Vasan RS, Dohrn IM, Hagströmer M, Edwardson C, Yates T, Shiroma EJ, Dempsey PC, Wijndaele K, Anderssen SA, Lee IM, Ekelund U

British Journal of Sports Medicine. Nov 2021

(DOI : 10.1136/bjsports-2021-104827)

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Physical activity intensity profiles associated with cardiometabolic risk in middle-aged to older men and women.

Dempsey PC, Aadland E, Strain T, Kvalheim OM, Westgate K, Lindsay T, Khaw KT, Wareham NJ, Brage S, Wijndaele K

Preventive medicine. May 2021

(DOI : 10.1016/j.ypmed.2022.106977)

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Effects of sedentary behaviour interventions on biomarkers of cardiometabolic risk in adults: systematic review with meta-analyses.

Hadgraft NT, Winkler E, Climie RE, Grace MS, Romero L, Owen N, Dunstan D, Healy G, Dempsey PC

British Journal of Sports Medicine. Mar 2020

(DOI : 10.1136/bjsports-2019-101154)

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Wearable-device-measured physical activity and future health risk.

Strain T, Wijndaele K, Dempsey PC, Sharp SJ, Pearce M, Jeon J, Lindsay T, Wareham N, Brage S

Nature medicine. Dec 2019

(DOI : 10.1038/s41591-020-1012-3)

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Impact of follow-up time and analytical approaches to account for reverse causality on the association between physical activity and health outcomes in UK Biobank.

Strain T, Wijndaele K, Sharp SJ, Dempsey PC, Wareham N, Brage S

International Journal of Epidemiology. Sep 2019

(DOI : 10.1093/ije/dyz212)

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Sedentary Behavior and Chronic Disease: Mechanisms and Future Directions.

Dempsey PC, Matthews CE, Dashti SG, Doherty AR, Bergouignan A, van Roekel EH, Dunstan DW, Wareham NJ, Yates TE, Wijndaele K, Lynch BM

Journal of physical activity & health. Aug 2019

(DOI : 10.1123/jpah.2019-0377)

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Effect of Morning Exercise With or Without Breaks in Prolonged Sitting on Blood Pressure in Older Overweight/Obese Adults.

Wheeler MJ, Dunstan DW, Ellis KA, Cerin E, Phillips S, Lambert G, Naylor LH, Dempsey PC, Kingwell BA, Green DJ

Hypertension (Dallas, Tex. : 1979). Feb 2019

(DOI : 10.1161/HYPERTENSIONAHA.118.12373)

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Sitting Less and Moving More: Implications for Hypertension.

Dempsey PC, Larsen RN, Dunstan DW, Owen N, Kingwell BA

Hypertension (Dallas, Tex. : 1979). Oct 2018

(DOI : 10.1161/HYPERTENSIONAHA.118.11190)

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Associations of context-specific sitting time with markers of cardiometabolic risk in Australian adults.

Dempsey PC, Hadgraft NT, Winkler EAH, Clark BK, Buman MP, Gardiner PA, Owen N, Lynch BM, Dunstan DW

The international journal of behavioral nutrition and physical activity. Jun 2018

(DOI : 10.1186/s12966-018-0748-3)

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