MRC Epidemiology Unit

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Apr 2018

(DOI : 10.1158/1055-9965.EPI-18-0400)

Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women.

Khaw KT, Sharp SJ, Finikarides L, Afzal I, Lentjes M, Luben R, Forouhi NG

BMJ Open. Mar 2018

(DOI : 10.1136/bmjopen-2017-020167)

Effect of interventions incorporating personalised cancer risk information on intentions and behaviour: a systematic review and meta-analysis of randomised controlled trials.

Usher-Smith JA, Silarova B, Sharp SJ, Mills K, Griffin SJ

BMJ Open. Jan 2018

(DOI : 10.1136/bmjopen-2017-017717)

Randomised controlled trial of a theory-based behavioural intervention to reduce formula milk intake.

Lakshman R, Sharp SJ, Whittle F, Schiff A, Hardeman W, Irvine L, Wilson E, Griffin SJ, Ong KK

Archives of Disease in Childhood. Jan 2018

(DOI : 10.1136/archdischild-2018-314784)

Impact of physical activity on the risk of cardiovascular disease in middle-aged and older adults: EPIC Norfolk prospective population study.

Lachman S, Boekholdt SM, Luben RN, Sharp SJ, Brage S, Khaw KT, Peters RJ, Wareham NJ

European Journal of Preventive Cardiology. Nov 2017

(DOI : 10.1177/2047487317737628)

Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality.

Panter J, Mytton OT, Sharp SJ, Brage S, Cummins S, Laverty AA, Wijndaele K, Ogilvie D

Heart (British Cardiac Society). Nov 2017

(DOI : 10.1136/heartjnl-2017-312699)

Interplay between genetic predisposition, macronutrient intake and type 2 diabetes incidence: analysis within EPIC-InterAct across eight European countries.

Li SX, Imamura F, Schulze MB, Zheng J, Ye Z, Agudo A, Ardanaz E, Aune D, Boeing H, Dorronsoro M, Dow C, Fagherazzi G, Grioni S, Gunter MJ, Huerta JM, Ibsen DB, Jakobsen MU, Kaaks R, Key TJ, Khaw KT, Kyrø C, Mancini FR, Molina-Portillo E, Murphy N, Nilsson PM, Onland-Moret NC, Palli D, Panico S, Poveda A, Quirós JR, Ricceri F, Sluijs I, Spijkerman AMW, Tjonneland A, Tumino R, Winkvist A, Langenberg C, Sharp SJ, Riboli E, Scott RA, Forouhi NG, Wareham NJ

Diabetologia. Oct 2017

(DOI : 10.1007/s00125-018-4586-2)

Circulating Fetuin-A and Risk of Type 2 Diabetes: A Mendelian Randomization Analysis.

Kröger J, Meidtner K, Stefan N, Guevara M, Kerrison ND, Ardanaz E, Aune D, Boeing H, Dorronsoro M, Fagherazzi G, Franks PW, Freisling H, Gunter MJ, Huerta JM, Kaaks R, Key TJ, Khaw KT, Krogh V, Kühn T, Mancini FR, Mattiello A, Nilsson PM, Olsen A, Overvad K, Palli D, Quirós JR, Rolandsson O, Sacerdote C, Sala N, Salamanca-Fernández E, Sluijs I, Spijkerman AMW, Tjonneland A, Tsilidis KK, Tumino R, van der Schouw YT, Forouhi NG, Sharp SJ, Langenberg C, Riboli E, Schulze MB, Wareham NJ

Diabetes. Oct 2017

(DOI : 10.2337/db17-1268)

A two-step method for variable selection in the analysis of a case-cohort study.

Sharp SJ

International Journal of Epidemiology. Oct 2017

(DOI : 10.1093/ije/dyx224)

Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis.

Sharp SJ, Woodcock J, Brage S, Wijndaele K

European Journal of Epidemiology. Oct 2017

(DOI : 10.1007/s10654-018-0380-1)

Sedentary behaviour and risk of all-cause, cardiovascular and cancer mortality, and incident type 2 diabetes: a systematic review and dose response meta-analysis.

Patterson R, McNamara E, Tainio M, de Sá TH, Smith AD, Sharp SJ, Edwards P, Woodcock J, Brage S, Wijndaele K

European Journal of Epidemiology. Oct 2017

(DOI : 10.1007/s10654-018-0380-1)

A cluster randomised controlled trial to evaluate the effectiveness and cost-effectiveness of the GoActive intervention to increase physical activity among adolescents aged 13-14 years.

Brown HE, Whittle F, Jong ST, Croxson C, Sharp SJ, Wilkinson P, Wilson EC, Van Sluijs EM, Vignoles A, Corder KL

BMJ Open. Oct 2017

(DOI : 10.1136/bmjopen-2016-014419)

External validation of risk prediction models for incident colorectal cancer using UK Biobank.

Usher-Smith JA, Harshfield A, Saunders CL, Sharp SJ, Emery J, Walter FM, Muir K, Griffin SJ

British journal of cancer. Sep 2017

(DOI : 10.1038/bjc.2017.463)

The combination of cardiorespiratory fitness and muscle strength, and mortality risk.

Kim Y, White T, Wijndaele K, Westgate K, Sharp SJ, Helge JW, Wareham NJ, Brage S

European Journal of Epidemiology. Aug 2017

(DOI : 10.1007/s10654-018-0384-x)

Association between plasma phospholipid saturated fatty acids and metabolic markers of lipid, hepatic, inflammation and glycaemic pathways in eight European countries: a cross-sectional analysis in the EPIC-InterAct study.

Zheng JS, Sharp SJ, Imamura F, Koulman A, Schulze MB, Ye Z, Griffin J, Guevara M, Huerta JM, Kröger J, Sluijs I, Agudo A, Barricarte A, Boeing H, Colorado-Yohar S, Dow C, Dorronsoro M, Dinesen PT, Fagherazzi G, Franks PW, Feskens EJM, Kühn T, Katzke VA, Key TJ, Khaw KT, De Magistris MS, Mancini FR, Molina-Portillo E, Nilsson PM, Olsen A, Overvad K, Palli D, Quirós JR, Rolandsson O, Ricceri F, Spijkerman AMW, Slimani N, Tagliabue G, Tjonneland A, Tumino R, van der Schouw YT, Langenberg C, Riboli E, Forouhi NG, Wareham NJ

BMC medicine. Jun 2017

(DOI : 10.1186/s12916-017-0968-4)

A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study.

Imamura F, Sharp SJ, Koulman A, Schulze MB, Kröger J, Griffin JL, Huerta JM, Guevara M, Sluijs I, Agudo A, Ardanaz E, Balkau B, Boeing H, Chajès V, Dahm CC, Fagherazzi G, Franks PW, Gavrila D, Gunter M, Kaaks R, Key TJ, Khaw KT, Kühn T, Melander O, Molina-Portillo E, Nilsson PM, Olsen A, Overvad K, Palli D, Panico S, Rolandsson O, Sieri S, Sacerdote C, Slimani N, Tjønneland A, Tumino R, van der Schouw YT, Langenberg C, Riboli E, Forouhi NG, Wareham NJ

PLoS Medicine. Jun 2017

(DOI : 10.1371/journal.pmed.1002409)

Interaction of Dietary and Genetic Factors Influencing Body Iron Status and Risk of Type 2 Diabetes Within the EPIC-InterAct Study.

Meidtner K, Podmore C, Kröger J, van der Schouw YT, Bendinelli B, Agnoli C, Arriola L, Barricarte A, Boeing H, Cross AJ, Dow C, Ekblom K, Fagherazzi G, Franks PW, Gunter MJ, Huerta JM, Jakszyn P, Jenab M, Katzke VA, Key TJ, Khaw KT, Kühn T, Kyrø C, Mancini FR, Melander O, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Rodriguez-Barranco M, Sacerdote C, Sluijs I, Stepien M, Tjonneland A, Tumino R, Forouhi NG, Sharp SJ, Langenberg C, Schulze MB, Riboli E, Wareham NJ

Diabetes care. May 2017

(DOI : 10.2337/dc17-1080)

Independent and joint associations of grip strength and adiposity with all-cause and cardiovascular disease mortality in 403,199 adults: the UK Biobank study.

Kim Y, Wijndaele K, Lee DC, Sharp SJ, Wareham N, Brage S

The American Journal of Clinical Nutrition. Mar 2017

(DOI : 10.3945/ajcn.117.156851)

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, Porneala BC, Sharp SJ, Jia Y, Kabagambe EK, Chang LC, Chen WM, Elks CE, Evans DS, Fan Q, Giulianini F, Go MJ, Hottenga JJ, Hu Y, Jackson AU, Kanoni S, Kim YJ, Kleber ME, Ladenvall C, Lecoeur C, Lim SH, Lu Y, Mahajan A, Marzi C, Nalls MA, Navarro P, Nolte IM, Rose LM, Rybin DV, Sanna S, Shi Y, Stram DO, Takeuchi F, Tan SP, van der Most PJ, Van Vliet-Ostaptchouk JV, Wong A, Yengo L, Zhao W, Goel A, Martinez Larrad MT, Radke D, Salo P, Tanaka T, van Iperen EPA, Abecasis G, Afaq S, Alizadeh BZ, Bertoni AG, Bonnefond A, Böttcher Y, Bottinger EP, Campbell H, Carlson OD, Chen CH, Cho YS, Garvey WT, Gieger C, Goodarzi MO, Grallert H, Hamsten A, Hartman CA, Herder C, Hsiung CA, Huang J, Igase M, Isono M, Katsuya T, Khor CC, Kiess W, Kohara K, Kovacs P, Lee J, Lee WJ, Lehne B, Li H, Liu J, Lobbens S, Luan J, Lyssenko V, Meitinger T, Miki T, Miljkovic I, Moon S, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nauck M, Pankow JS, Polasek O, Prokopenko I, Ramos PS, Rasmussen-Torvik L, Rathmann W, Rich SS, Robertson NR, Roden M, Roussel R, Rudan I, Scott RA, Scott WR, Sennblad B, Siscovick DS, Strauch K, Sun L, Swertz M, Tajuddin SM, Taylor KD, Teo YY, Tham YC, Tönjes A, Wareham NJ, Willemsen G, Wilsgaard T, Hingorani AD, EPIC-CVD Consortium, EPIC-InterAct Consortium, Lifelines Cohort Study, Egan J, Ferrucci L, Hovingh GK, Jula A, Kivimaki M, Kumari M, Njølstad I, Palmer CNA, Serrano Ríos M, Stumvoll M, Watkins H, Aung T, Blüher M, Boehnke M, Boomsma DI, Bornstein SR, Chambers JC, Chasman DI, Chen YI, Chen YT, Cheng CY, Cucca F, de Geus EJC, Deloukas P, Evans MK, Fornage M, Friedlander Y, Froguel P, Groop L, Gross MD, Harris TB, Hayward C, Heng CK, Ingelsson E, Kato N, Kim BJ, Koh WP, Kooner JS, Körner A, Kuh D, Kuusisto J, Laakso M, Lin X, Liu Y, Loos RJF, Magnusson PKE, März W, McCarthy MI, Oldehinkel AJ, Ong KK, Pedersen NL, Pereira MA, Peters A, Ridker PM, Sabanayagam C, Sale M, Saleheen D, Saltevo J, Schwarz PE, Sheu WHH, Snieder H, Spector TD, Tabara Y, Tuomilehto J, van Dam RM, Wilson JG, Wilson JF, Wolffenbuttel BHR, Wong TY, Wu JY, Yuan JM, Zonderman AB, Soranzo N, Guo X, Roberts DJ, Florez JC, Sladek R, Dupuis J, Morris AP, Tai ES, Selvin E, Rotter JI, Langenberg C, Barroso I, Meigs JB

PLoS Medicine. Feb 2017

(DOI : 10.1371/journal.pmed.1002383)

Adiposity and grip strength as long-term predictors of objectively measured physical activity in 93 015 adults: the UK Biobank study.

Kim Y, White T, Wijndaele K, Sharp SJ, Wareham NJ, Brage S

International Journal of Obesity. Jan 2017

(DOI : 10.1038/ijo.2017.122)

Mortality Risk Reductions from Substituting Screen Time by Discretionary Activities.

Wijndaele K, Sharp SJ, Wareham NJ, Brage S

Medicine and Science in Sports and Exercise. Jan 2017

(DOI : 10.1249/MSS.0000000000001206)

Interaction between genes and macronutrient intake on the risk of developing type 2 diabetes: systematic review and findings from European Prospective Investigation into Cancer (EPIC)-InterAct.

Li SX, Imamura F, Ye Z, Schulze MB, Zheng J, Ardanaz E, Arriola L, Boeing H, Dow C, Fagherazzi G, Franks PW, Agudo A, Grioni S, Kaaks R, Katzke VA, Key TJ, Khaw KT, Mancini FR, Navarro C, Nilsson PM, Onland-Moret NC, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sánchez MJ, Slimani N, Sluijs I, Spijkerman AM, Tjonneland A, Tumino R, Sharp SJ, Riboli E, Langenberg C, Scott RA, Forouhi NG, Wareham NJ

The American Journal of Clinical Nutrition. Dec 2016

(DOI : 10.3945/ajcn.116.150094)

Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.

Lotta LA, Sharp SJ, Burgess S, Perry JR, Stewart ID, Willems S, Luan J, Ardanaz E, Arriola L, Balkau B, Boeing H, Deloukas P, Forouhi NG, Franks PW, Grioni S, Kaaks R, Key TJ, Navarro C, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Riboli E, Rolandsson O, Sacerdote C, Slimani N, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, van der Schouw YT, McCarthy MI, Barroso I, O'Rahilly S, Savage DB, Sattar N, Langenberg C, Scott RA, Wareham NJ

JAMA. Oct 2016

(DOI : 10.1001/jama.2016.14568)

Premenopausal abnormal uterine bleeding and risk of endometrial cancer.

Pennant ME, Mehta R, Moody P, Hackett G, Prentice A, Sharp SJ, Lakshman R

BJOG : an international journal of obstetrics and gynaecology. Sep 2016

(DOI : 10.1111/1471-0528.14385)

A randomised trial of the effect and cost-effectiveness of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with screen-detected type 2 diabetes: the Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (ADDITION-Europe) study.

Simmons RK, Borch-Johnsen K, Lauritzen T, Rutten GE, Sandbæk A, van den Donk M, Black JA, Tao L, Wilson EC, Davies MJ, Khunti K, Sharp SJ, Wareham NJ, Griffin SJ

Health technology assessment (Winchester, England). Sep 2016

(DOI : 10.3310/hta20640)

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis.

Lotta LA, Scott RA, Sharp SJ, Burgess S, Luan J, Tillin T, Schmidt AF, Imamura F, Stewart ID, Perry JR, Marney L, Koulman A, Karoly ED, Forouhi NG, Sjögren RJ, Näslund E, Zierath JR, Krook A, Savage DB, Griffin JL, Chaturvedi N, Hingorani AD, Khaw KT, Barroso I, McCarthy MI, O'Rahilly S, Wareham NJ, Langenberg C

PLoS Medicine. Aug 2016

(DOI : 10.1371/journal.pmed.1002179)

Lifestyle Advice Combined with Personalized Estimates of Genetic or Phenotypic Risk of Type 2 Diabetes, and Objectively Measured Physical Activity: A Randomized Controlled Trial.

Godino JG, Van Sluijs EM, Marteau TM, Sutton S, Sharp SJ, Griffin SJ

PLoS Medicine. Jul 2016

(DOI : 10.1371/journal.pmed.1002185)

The spectrum effect in tests for risk prediction, screening, and diagnosis.

Usher-Smith JA, Sharp SJ, Griffin SJ

BMJ (Clinical research ed.). Jun 2016

(DOI : 10.1136/bmj.i3139)

Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study.

Forouhi NG, Imamura F, Sharp SJ, Koulman A, Schulze MB, Zheng J, Ye Z, Sluijs I, Guevara M, Huerta JM, Kröger J, Wang LY, Summerhill K, Griffin JL, Feskens EJ, Affret A, Amiano P, Boeing H, Dow C, Fagherazzi G, Franks PW, Gonzalez C, Kaaks R, Key TJ, Khaw KT, Kühn T, Mortensen LM, Nilsson PM, Overvad K, Pala V, Palli D, Panico S, Quirós JR, Rodriguez-Barranco M, Rolandsson O, Sacerdote C, Scalbert A, Slimani N, Spijkerman AM, Tjonneland A, Tormo MJ, Tumino R, van der A DL, van der Schouw YT, Langenberg C, Riboli E, Wareham NJ

PLoS Medicine. May 2016

(DOI : 10.1371/journal.pmed.1002094)

Corder K, Sharp SJ, Atkin AJ, Andersen LB, Cardon G, Page A, Davey R, Grøntved A, Hallal PC, Janz KF, Kordas K, Kriemler S, Puder JJ, Sardinha LB, Ekelund U, Van Sluijs EM, International Childrens Accelerometry Database (ICAD) Collaborators

Preventive medicine reports. May 2016

(DOI : 10.1016/j.pmedr.2016.05.006)

Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.

Lotta LA, Gulati P, Day FR, Payne F, Ongen H, van de Bunt M, Gaulton KJ, Eicher JD, Sharp SJ, Luan J, De Lucia Rolfe E, Stewart ID, Wheeler E, Willems SM, Adams C, Yaghootkar H, EPIC-InterAct Consortium, Cambridge FPLD1 Consortium, Forouhi NG, Khaw KT, Johnson AD, Semple RK, Frayling T, Perry JR, Dermitzakis E, McCarthy MI, Barroso I, Wareham NJ, Savage DB, Langenberg C, O'Rahilly S, Scott RA

Nature genetics. Apr 2016

(DOI : 10.1038/ng.3714)

Residential neighbourhood greenspace is associated with reduced risk of incident diabetes in older people: a prospective cohort study.

Jones AP, Sharp SJ, Cooper AJ, Griffin SJ, Wareham NJ

BMC Public Health. Apr 2016

(DOI : 10.1186/s12889-016-3833-z)

Residential neighbourhood greenspace is associated with reduced risk of incident diabetes in older people: a prospective cohort study.

Dalton AM, Jones AP, Sharp SJ, Cooper AJ, Griffin SJ, Wareham NJ

BMC Public Health. Apr 2016

(DOI : 10.1186/s12889-016-3833-z)

Glucocorticoid-induced hyperglycaemia in respiratory disease: a systematic review and meta-analysis.

Sharp SJ

Diabetes, obesity & metabolism. Mar 2016

(DOI : 10.1111/dom.12739)

Bidirectional association between physical activity and muscular strength in older adults: Results from the UK Biobank study.

Cooper A, Lamb MJE, Sharp SJ, Simmons RK, Griffin SJ

International Journal of Epidemiology. Feb 2016

(DOI : 10.1093/ije/dyw054)

Fruit and vegetable intake and cardiovascular risk factors in people with newly diagnosed type 2 diabetes.

Lamb MJE, Griffin SJ, Sharp SJ, Cooper AJ

European Journal of Clinical Nutrition. Feb 2016

(DOI : 10.1038/ejcn.2016.180)

The independent prospective associations of activity intensity and dietary energy density with adiposity in young adolescents.

Van Sluijs EM, Sharp SJ, Ambrosini GL, Cassidy A, Griffin SJ, Ekelund U

The British journal of nutrition. Jan 2016

(DOI : 10.1017/S0007114515005097)

Effects of vitamin D2 or D3 supplementation on glycaemic control and cardiometabolic risk among people at risk of type 2 diabetes: results of a randomized double-blind placebo-controlled trial.

Forouhi NG, Menon RK, Sharp SJ, Mannan N, Timms PM, Martineau AR, Rickard AP, Boucher BJ, Chowdhury TA, Griffiths CJ, Greenwald SE, Griffin SJ, Hitman GA

Diabetes, obesity & metabolism. Nov 2015

(DOI : 10.1111/dom.12625)

Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI Categories: A Systematic Review and Network Meta-analysis.

Lotta LA, Abbasi A, Sharp SJ, Sahlqvist AS, Waterworth D, Brosnan JM, Scott RA, Langenberg C, Wareham NJ

Diabetes care. Oct 2015

(DOI : 10.2337/dc15-1218)

Seasonal Variation in Children's Physical Activity and Sedentary Time.

Atkin AJ, Sharp SJ, Harrison F, Brage S, Van Sluijs EM

Medicine and Science in Sports and Exercise. Oct 2015

(DOI : 10.1249/MSS.0000000000000786)

Seasonal Variation in Children's Physical Activity and Sedentary Time

Brage S, Van Sluijs EM, Atkin AJ, Harrison F, Sharp SJ

Medicine and Science in Sports and Exercise. Oct 2015

(DOI : 10.1249/MSS.0000000000000786)

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

Scott RA, Freitag DF, Li L, Chu AY, Surendran P, Young R, Grarup N, Stančáková A, Chen Y, Varga TV, Yaghootkar H, Luan J, Zhao JH, Willems SM, Wessel J, Wang S, Maruthur N, Michailidou K, Pirie A, van der Lee SJ, Gillson C, Al Olama AA, Amouyel P, Arriola L, Arveiler D, Aviles-Olmos I, Balkau B, Barricarte A, Barroso I, Garcia SB, Bis JC, Blankenberg S, Boehnke M, Boeing H, Boerwinkle E, Borecki IB, Bork-Jensen J, Bowden S, Caldas C, Caslake M, CVD50 consortium, Cupples LA, Cruchaga C, Czajkowski J, den Hoed M, Dunn JA, Earl HM, Ehret GB, Ferrannini E, Ferrières J, Foltynie T, Ford I, Forouhi NG, Gianfagna F, Gonzalez C, Grioni S, Hiller L, Jansson JH, Jørgensen ME, Jukema JW, Kaaks R, Kee F, Kerrison ND, Key TJ, Kontto J, Kote-Jarai Z, Kraja AT, Kuulasmaa K, Kuusisto J, Linneberg A, Liu C, Marenne G, Mohlke KL, Morris AP, Muir K, Müller-Nurasyid M, Munroe PB, Navarro C, Nielsen SF, Nilsson PM, Nordestgaard BG, Packard CJ, Palli D, Panico S, Peloso GM, Perola M, Peters A, Poole CJ, Quirós JR, Rolandsson O, Sacerdote C, Salomaa V, Sánchez MJ, Sattar N, Sharp SJ, Sims R, Slimani N, Smith JA, Thompson DJ, Trompet S, Tumino R, van der A DL, van der Schouw YT, Virtamo J, Walker M, Walter K, GERAD_EC Consortium, Neurology Working Group of the Cohorts for Heart, Aging Research in Genomic Epidemiology (CHARGE) Aging Research in Genomic Epidemiology (CHARGE), Alzheimer’s Disease Genetics Consortium, Pancreatic Cancer Cohort Consortium, European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD), EPIC-InterAct EPIC-InterAct, Abraham JE, Amundadottir LT, Aponte JL, Butterworth AS, Dupuis J, Easton DF, Eeles RA, Erdmann J, Franks PW, Frayling TM, Hansen T, Howson JM, Jørgensen T, Kooner J, Laakso M, Langenberg C, McCarthy MI, Pankow JS, Pedersen O, Riboli E, Rotter JI, Saleheen D, Samani NJ, Schunkert H, Vollenweider P, O'Rahilly S, CHARGE Consortium, CHD Exome+ Consortium, CARDIoGRAM Exome Consortium, Deloukas P, Danesh J, Goodarzi MO, Kathiresan S, Meigs JB, Ehm MG, Wareham NJ, Waterworth DM

Science translational medicine. Sep 2015

(DOI : 10.1126/scitranslmed.aad3744)

Information and Risk Modification Trial (INFORM): design of a randomised controlled trial of communicating different types of information about coronary heart disease risk, alongside lifestyle advice, to achieve change in health-related behaviour.

Silarova B, Lucas J, Butterworth AS, Di Angelantonio E, Girling C, Lawrence K, Mackintosh S, Moore C, Payne RA, Sharp SJ, Shefer G, Tolkien Z, Usher-Smith J, Walker M, Danesh J, Griffin SJ

BMC Public Health. Jul 2015

(DOI : 10.1186/s12889-015-2192-5)

Reply to H Pareja-Galeano et al.

Ekelund U, Ward H, Luan J, Sharp SJ, Brage S, Wareham NJ

The American Journal of Clinical Nutrition. May 2015

(DOI : 10.3945/ajcn.115.108696)

The UK-PBC risk scores: Derivation and validation of a scoring system for long-term prediction of end-stage liver disease in primary biliary cholangitis.

Carbone M, Sharp SJ, Flack S, Paximadas D, Spiess K, Adgey C, Griffiths L, Lim R, Trembling P, Williamson K, Wareham NJ, Aldersley M, Bathgate A, Burroughs AK, Heneghan MA, Neuberger JM, Thorburn D, Hirschfield GM, Cordell HJ, Alexander GJ, Jones DE, Sandford RN, Mells GF, UK-PBC Consortium

Hepatology (Baltimore, Md.). Apr 2015

(DOI : 10.1002/hep.28017)

Protocol for Get Moving: a randomised controlled trial to assess the effectiveness of three minimal contact interventions to promote fitness and physical activity in working adults

Brage S, Griffin SJ, Van Sluijs EM, Cooper AJ, Dearnley K, Sharp SJ, Sutton S, Williams KM

BMC Public Health. Mar 2015

(DOI : 10.1186/s12889-015-1654-0)

The pathway to diagnosis of type 1 diabetes in children: a questionnaire study.

Sharp SJ

BMJ Open. Mar 2015

(DOI : 10.1136/bmjopen-2014-006470)

Protocol for Get Moving: a randomised controlled trial to assess the effectiveness of three minimal contact interventions to promote fitness and physical activity in working adults.

Cooper AJ, Dearnley K, Williams KM, Sharp SJ, Van Sluijs EM, Brage S, Sutton S, Griffin SJ

BMC Public Health. Mar 2015

(DOI : 10.1186/s12889-015-1654-0)

Physical activity and all-cause mortality across levels of overall and abdominal adiposity in European men and women: the European Prospective Investigation into Cancer and Nutrition Study (EPIC).

Ekelund U, Ward HA, Norat T, Luan J, May AM, Weiderpass E, Sharp SJ, Overvad K, Østergaard JN, Tjønneland A, Johnsen NF, Mesrine S, Fournier A, Fagherazzi G, Trichopoulou A, Lagiou P, Trichopoulos D, Li K, Kaaks R, Ferrari P, Licaj I, Jenab M, Bergmann M, Boeing H, Palli D, Sieri S, Panico S, Tumino R, Vineis P, Peeters PH, Monnikhof E, Bueno-de-Mesquita HB, Quirós JR, Agudo A, Sánchez MJ, Huerta JM, Ardanaz E, Arriola L, Hedblad B, Wirfält E, Sund M, Johansson M, Key TJ, Travis RC, Khaw KT, Brage S, Wareham NJ, Riboli E

The American Journal of Clinical Nutrition. Mar 2015

(DOI : 10.3945/ajcn.114.100065)

Repeat Cardiovascular Risk Assessment after Four Years: Is There Improvement in Risk Prediction?

Chamnan P, Simmons RK, Sharp SJ, Khaw KT, Wareham NJ, Griffin SJ

PLoS ONE. Feb 2015

(DOI : 10.1371/journal.pone.0147417)

Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.

Podmore C, Meidtner K, Schulze MB, Scott RA, Butterworth AS, Di Angelantonio E, Danesh J, Arriola L, Barricarte A, Boeing H, Clavel-Chapelon F, Cross AJ, Dahm CC, Fagherazzi G, Franks PW, Gavrila D, Grioni S, Gunter MJ, Gusto G, Jakszyn P, Katzke V, Key TJ, Kühn T, Mattiello A, Nilsson PM, Olsen A, Overvad K, Palli D, Quirós JR, Rolandsson O, Sacerdote C, Sánchez-Cantalejo E, Slimani N, Sluijs I, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, van der Schouw YT, Feskens EJ, Forouhi NG, Sharp SJ, Riboli E, Langenberg C, Wareham NJ

Diabetes care. Feb 2015

(DOI : PMC5058436)

Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis.

Nead KT, Sharp SJ, Thompson DJ, Painter JN, Savage DB, Semple RK, Barker A, Australian National Endometrial Cancer Study Group (ANECS), Perry JR, Attia J, Dunning AM, Easton DF, Holliday E, Lotta LA, O'Mara T, McEvoy M, Pharoah PD, Scott RJ, Spurdle AB, Langenberg C, Wareham NJ, Scott RA

Journal of the National Cancer Institute. Jan 2015

(DOI : 10.1093/jnci/djv178)

Association between 25-hydroxyvitamin D and type 2 diabetes--authors' reply.

Forouhi NG, Sharp SJ, Ye Zheng, Imamura F, Burgess S

The lancet. Diabetes & endocrinology. Jan 2015

(DOI : 10.1016/S2213-8587(14)70247-5)

Untargeted metabolic profiling identifies altered serum metabolites of type 2 diabetes mellitus in a prospective, nested case control study.

Drogan D, Dunn WB, Lin W, Buijsse B, Schulze MB, Langenberg C, Brown M, Floegel A, Dietrich S, Rolandsson O, Wedge DC, Goodacre R, Forouhi NG, Sharp SJ, Spranger J, Wareham NJ, Boeing H

Clinical chemistry. Dec 2014

(DOI : 10.1373/clinchem.2014.228965)

A method making fewer assumptions gave the most reliable estimates of exposure-outcome associations in stratified case-cohort studies.

Sharp SJ, Thompson SG

Journal of clinical epidemiology. Dec 2014

(DOI : 10.1016/j.jclinepi.2015.04.007)

Change in cardio-protective medication and health-related quality of life after diagnosis of screen-detected diabetes: Results from the ADDITION-Cambridge cohort.

Black JA, Long GH, Sharp SJ, Kuznetsov L, Boothby CE, Griffin SJ, Simmons RK

Diabetes Research and Clinical Practice. Nov 2014

(DOI : 10.1016/j.diabres.2015.04.013)

Prospective associations between sedentary time, sleep duration and adiposity in adolescents.

Collings PJ, Wijndaele K, Corder KL, Westgate K, Ridgway CL, Sharp SJ, Atkin AJ, Bamber D, Goodyer I, Brage S, Ekelund U

Sleep medicine. Nov 2014

(DOI : 10.1016/j.sleep.2015.02.532)

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.

Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA

PLoS Medicine. Nov 2014

(DOI : 10.1371/journal.pmed.1001841)

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.

Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA

PLoS Medicine. Nov 2014

(DOI : 10.1371/journal.pmed.1001841)

Smoking and long-term risk of type 2 diabetes: the EPIC-InterAct study in European populations.

Spijkerman AM, van der A DL, Nilsson PM, Ardanaz E, Gavrila D, Agudo A, Arriola L, Balkau B, Beulens JW, Boeing H, de Lauzon-Guillain B, Fagherazzi G, Feskens EJ, Franks PW, Grioni S, Huerta JM, Kaaks R, Key TJ, Overvad K, Palli D, Panico S, Redondo ML, Rolandsson O, Roswall N, Sacerdote C, Sánchez MJ, Schulze MB, Slimani N, Teucher B, Tjonneland A, Tumino R, van der Schouw YT, Langenberg C, Sharp SJ, Forouhi NG, Riboli E, Wareham NJ

Diabetes care. Oct 2014

(DOI : 10.2337/dc14-1020)

Inverse association between bone mineral density and risk of aortic stenosis in men and women in EPIC-Norfolk prospective study.

Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT

International journal of cardiology. Oct 2014

(DOI : 10.1016/j.ijcard.2014.10.065)

Association between circulating 25-hydroxyvitamin D and incident type 2 diabetes: a mendelian randomisation study.

Ye Z, Sharp SJ, Burgess S, Scott RA, Imamura F, InterAct Consortium, Langenberg C, Wareham NJ, Forouhi NG

The lancet. Diabetes & endocrinology. Oct 2014

(DOI : 10.1016/S2213-8587(14)70184-6)

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.

Swerdlow DI, Preiss D, Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T, Sofat R, Stender S, Johnson PC, Scott RA, Leusink M, Verweij N, Sharp SJ, Guo Y, Giambartolomei C, Chung C, Peasey A, Amuzu A, Li K, Palmen J, Howard P, Cooper JA, Drenos F, Li YR, Lowe G, Gallacher J, Stewart MC, Tzoulaki I, Buxbaum SG, van der A DL, Forouhi NG, Onland-Moret NC, van der Schouw YT, Schnabel RB, Hubacek JA, Kubinova R, Baceviciene M, Tamosiunas A, Pajak A, Topor-Madry R, Stepaniak U, Malyutina S, Baldassarre D, Sennblad B, Tremoli E, de Faire U, Veglia F, Ford I, Jukema JW, Westendorp RG, de Borst GJ, de Jong PA, Algra A, Spiering W, Maitland-van der Zee AH, Klungel OH, de Boer A, Doevendans PA, Eaton CB, Robinson JG, Duggan D, DIAGRAM Consortium, MAGIC Consortium, InterAct Consortium, Kjekshus J, Downs JR, Gotto AM, Keech AC, Marchioli R, Tognoni G, Sever PS, Poulter NR, Waters DD, Pedersen TR, Amarenco P, Nakamura H, McMurray JJ, Lewsey JD, Chasman DI, Ridker PM, Maggioni AP, Tavazzi L, Ray KK, Seshasai SR, Manson JE, Price JF, Whincup PH, Morris RW, Lawlor DA, Smith GD, Ben-Shlomo Y, Schreiner PJ, Fornage M, Siscovick DS, Cushman M, Kumari M, Wareham NJ, Verschuren WM, Redline S, Patel SR, Whittaker JC, Hamsten A, Delaney JA, Dale C, Gaunt TR, Wong A, Kuh D, Hardy R, Kathiresan S, Castillo BA, van der Harst P, Brunner EJ, Tybjaerg-Hansen A, Marmot MG, Krauss RM, Tsai M, Coresh J, Hoogeveen RC, Psaty BM, Lange LA, Hakonarson H, Dudbridge F, Humphries SE, Talmud PJ, Kivimaki M, Timpson NJ, Langenberg C, Asselbergs FW, Voevoda M, Bobak M, Pikhart H, Wilson JG, Reiner AP, Keating BJ, Hingorani AD, Sattar N

Lancet (London, England). Sep 2014

(DOI : 10.1016/S0140-6736(14)61183-1)

Plasma vitamin C and risk of hospitalisation with diagnosis of atrial fibrillation in men and women in EPIC-Norfolk prospective study.

Pfister R, Michels G, Brägelmann J, Sharp SJ, Luben R, Wareham NJ, Khaw KT

International journal of cardiology. Sep 2014

(DOI : 10.1016/j.ijcard.2014.11.016)

Tinned fruit consumption and mortality in three prospective cohorts.

Aasheim ET, Sharp SJ, Appleby PN, Shipley MJ, Lentjes MA, Khaw KT, Brunner E, Key TJ, Wareham NJ

PLoS ONE. Sep 2014

(DOI : 10.1371/journal.pone.0117796)

Objectively measured physical activity and longitudinal changes in adolescent body fatness: an observational cohort study.

Collings PJ, Wijndaele K, Corder KL, Westgate K, Ridgway CL, Sharp SJ, Atkin AJ, Stephen AM, Bamber D, Goodyer I, Brage S, Ekelund U

Pediatric Obesity. Aug 2014

(DOI : 10.1111/ijpo.12031)

Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study.

Forouhi NG, Koulman A, Sharp SJ, Imamura F, Kröger J, Schulze MB, Crowe FL, Huerta JM, Guevara M, Beulens JW, van Woudenbergh GJ, Wang L, Summerhill K, Griffin JL, Feskens EJ, Amiano P, Boeing H, Clavel-Chapelon F, Dartois L, Fagherazzi G, Franks PW, Gonzalez C, Jakobsen MU, Kaaks R, Key TJ, Khaw KT, Kühn T, Mattiello A, Nilsson PM, Overvad K, Pala V, Palli D, Quirós JR, Rolandsson O, Roswall N, Sacerdote C, Sánchez MJ, Slimani N, Spijkerman AM, Tjonneland A, Tormo MJ, Tumino R, van der A DL, van der Schouw YT, Langenberg C, Riboli E, Wareham NJ

The lancet. Diabetes & endocrinology. Aug 2014

(DOI : 10.1016/S2213-8587(14)70146-9)

Magnitude and determinants of change in objectively-measured physical activity, sedentary time and sleep duration from ages 15 to 17.5y in UK adolescents: the ROOTS study.

Collings PJ, Wijndaele K, Corder KL, Westgate K, Ridgway CL, Sharp SJ, Dunn V, Goodyer I, Ekelund U, Brage S

The international journal of behavioral nutrition and physical activity. Jul 2014

(DOI : 10.1186/s12966-015-0222-4)

Reply: The importance of ventricular-vascular uncoupling.

Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT

JACC. Heart failure. Jul 2014

(DOI : 10.1016/j.jchf.2014.07.004)

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, Leusink M, Sundström J, Hubacek JA, Pikhart H, Swerdlow DI, Panayiotou AG, Borinskaya SA, Finan C, Shah S, Kuchenbaecker KB, Shah T, Engmann J, Folkersen L, Eriksson P, Ricceri F, Melander O, Sacerdote C, Gamble DM, Rayaprolu S, Ross OA, McLachlan S, Vikhireva O, Sluijs I, Scott RA, Adamkova V, Flicker L, Bockxmeer FM, Power C, Marques-Vidal P, Meade T, Marmot MG, Ferro JM, Paulos-Pinheiro S, Humphries SE, Talmud PJ, Mateo Leach I, Verweij N, Linneberg A, Skaaby T, Doevendans PA, Cramer MJ, van der Harst P, Klungel OH, Dowling NF, Dominiczak AF, Kumari M, Nicolaides AN, Weikert C, Boeing H, Ebrahim S, Gaunt TR, Price JF, Lannfelt L, Peasey A, Kubinova R, Pajak A, Malyutina S, Voevoda MI, Tamosiunas A, Maitland-van der Zee AH, Norman PE, Hankey GJ, Bergmann MM, Hofman A, Franco OH, Cooper J, Palmen J, Spiering W, de Jong PA, Kuh D, Hardy R, Uitterlinden AG, Ikram MA, Ford I, Hyppönen E, Almeida OP, Wareham NJ, Khaw KT, Hamsten A, Husemoen LL, Tjønneland A, Tolstrup JS, Rimm E, Beulens JW, Verschuren WM, Onland-Moret NC, Hofker MH, Wannamethee SG, Whincup PH, Morris R, Vicente AM, Watkins H, Farrall M, Jukema JW, Meschia J, Cupples LA, Sharp SJ, Fornage M, Kooperberg C, Lacroix AZ, Dai JY, Lanktree MB, Siscovick DS, Jorgenson E, Spring B, Coresh J, Li YR, Buxbaum SG, Schreiner PJ, Ellison RC, Tsai MY, Patel SR, Redline S, Johnson AD, Hoogeveen RC, Hakonarson H, Rotter JI, Boerwinkle E, de Bakker PI, Kivimaki M, Asselbergs FW, Sattar N, Lawlor DA, Whittaker J, Davey Smith G, Mukamal K, Psaty BM, Wilson JG, Lange LA, Hamidovic A, Hingorani AD, Nordestgaard BG, Bobak M, Leon DA, Langenberg C, Palmer TM, Reiner AP, Keating BJ, Dudbridge F, Casas JP, InterAct Consortium

BMJ (Clinical research ed.). Jul 2014

(DOI : 10.1136/bmj.g4164)

Common genetic variants highlight the role of insulin resistance and body fat distribution in type 2 diabetes, independent of obesity.

Scott RA, Fall T, Pasko D, Barker A, Sharp SJ, Arriola L, Balkau B, Barricarte A, Barroso I, Boeing H, Clavel-Chapelon F, Crowe FL, Dekker JM, Fagherazzi G, Ferrannini E, Forouhi NG, Franks PW, Gavrila D, Giedraitis V, Grioni S, Groop LC, Kaaks R, Key TJ, Kühn T, Lotta LA, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Roswall N, Sacerdote C, Sala N, Sánchez MJ, Schulze MB, Siddiq A, Slimani N, Sluijs I, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, Yaghootkar H, McCarthy MI, Semple RK, Riboli E, Walker M, Ingelsson E, Frayling TM, Savage DB, Langenberg C, Wareham NJ

Diabetes. Jun 2014

(DOI : 10.2337/db14-0319)

A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.

Sluijs I, Holmes MV, van der Schouw YT, Beulens JW, Asselbergs FW, Huerta JM, Palmer TM, Arriola L, Balkau B, Barricarte A, Boeing H, Clavel-Chapelon F, Fagherazzi G, Franks PW, Gavrila D, Kaaks R, Khaw KT, Kühn T, Molina-Montes E, Mortensen LM, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sala N, Schmidt JA, Scott RA, Sieri S, Slimani N, Spijkerman AM, Tjonneland A, Travis RC, Tumino R, van der A DL, Sharp SJ, Forouhi NG, Langenberg C, Riboli E, Wareham NJ, InterAct Consortium

Diabetes. May 2014

(DOI : 10.2337/db14-0742)

Effect of early multifactorial therapy compared with routine care on microvascular outcomes at 5 years in people with screen-detected diabetes: a randomized controlled trial: the ADDITION-Europe Study.

Sandbæk A, Griffin SJ, Sharp SJ, Simmons RK, Borch-Johnsen K, Rutten GE, van den Donk M, Wareham NJ, Lauritzen T, Davies MJ, Khunti K

Diabetes care. May 2014

(DOI : 10.2337/dc13-1544)

The association between a biomarker score for fruit and vegetable intake and incident type 2 diabetes: the EPIC-Norfolk study.

Cooper AJ, Sharp SJ, Luben RN, Khaw KT, Wareham NJ, Forouhi NG

European Journal of Clinical Nutrition. Apr 2014

(DOI : 10.1038/ejcn.2014.246)

Dietary protein intake and incidence of type 2 diabetes in Europe: the EPIC-InterAct Case-Cohort Study.

van Nielen M, Feskens EJ, Mensink M, Sluijs I, Molina E, Amiano P, Ardanaz E, Balkau B, Beulens JW, Boeing H, Clavel-Chapelon F, Fagherazzi G, Franks PW, Halkjaer J, Huerta JM, Katzke V, Key TJ, Khaw KT, Krogh V, Kühn T, Menéndez VV, Nilsson P, Overvad K, Palli D, Panico S, Rolandsson O, Romieu I, Sacerdote C, Sánchez MJ, Schulze MB, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, Würtz AM, Zamora-Ros R, Langenberg C, Sharp SJ, Forouhi NG, Riboli E, Wareham NJ

Diabetes care. Apr 2014

(DOI : 10.2337/dc13-2627)

Change in cardiovascular risk factors following early diagnosis of type 2 diabetes: a cohort analysis of a cluster-randomised trial.

Black JA, Sharp SJ, Wareham NJ, Sandbæk A, Rutten GE, Lauritzen T, Khunti K, Davies MJ, Borch-Johnsen K, Griffin SJ, Simmons RK

The British journal of general practice : the journal of the Royal College of General Practitioners. Apr 2014

(DOI : 10.3399/bjgp14X677833)

Non-invasive risk scores for prediction of type 2 diabetes (EPIC-InterAct): a validation of existing models.

Kengne AP, Beulens JW, Peelen LM, Moons KG, van der Schouw YT, Schulze MB, Spijkerman AM, Griffin SJ, Grobbee DE, Palla L, Tormo MJ, Arriola L, Barengo NC, Barricarte A, Boeing H, Bonet C, Clavel-Chapelon F, Dartois L, Fagherazzi G, Franks PW, Huerta JM, Kaaks R, Key TJ, Khaw KT, Li K, Mühlenbruch K, Nilsson PM, Overvad K, Overvad TF, Palli D, Panico S, Quirós JR, Rolandsson O, Roswall N, Sacerdote C, Sánchez MJ, Slimani N, Tagliabue G, Tjønneland A, Tumino R, van der A DL, Forouhi NG, Sharp SJ, Langenberg C, Riboli E, Wareham NJ

The lancet. Diabetes & endocrinology. Mar 2014

(DOI : 10.1016/S2213-8587(13)70103-7)

Prevalence and correlates of screen time in youth: an international perspective.

Atkin AJ, Sharp SJ, Corder K, Van Sluijs EM, International Childrens Accelerometry Database (ICAD) Collaborators

American Journal of Preventive Medicine. Mar 2014

(DOI : 10.1016/j.amepre.2014.07.043)

Low bone mineral density predicts incident heart failure in men and women: the EPIC (European Prospective Investigation into Cancer and Nutrition)-Norfolk prospective study.

Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT

JACC. Heart failure. Feb 2014

(DOI : 10.1016/j.jchf.2014.03.010)

Physical activity, sedentary time and gain in overall and central body fat: 7-year follow-up of the ProActive trial cohort.

Golubic R, Wijndaele K, Sharp SJ, Simmons RK, Griffin SJ, Wareham NJ, Ekelund U, Brage S, ProActive Study Group

International Journal of Obesity. Jan 2014

(DOI : 10.1038/ijo.2014.66)

Objectively measured physical activity in four-year-old British children: a cross-sectional analysis of activity patterns segmented across the day

Van Sluijs EM, Collings PJ, Cooper C, Ekelund U, Godfrey KM, Harvey NC, Hesketh KR, Inskip HM, McMinn AM, Sharp SJ

International Journal of Behavioral Nutrition and Physical Activity. Jan 2014

(DOI : 10.1186/1479-5868-11-1)

Consumption of fatty foods and incident type 2 diabetes in populations from eight European countries.

Buijsse B, Boeing H, Drogan D, Schulze MB, Feskens EJ, Amiano P, Barricarte A, Clavel-Chapelon F, de Lauzon-Guillain B, Fagherazzi G, Fonseca-Nunes A, Franks PW, Huerta JM, Jakobsen MU, Kaaks R, Key TJ, Khaw KT, Masala G, Moskal A, Nilsson PM, Overvad K, Pala V, Panico S, Redondo ML, Ricceri F, Rolandsson O, Sánchez MJ, Sluijs I, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, van der Schouw YT, Langenberg C, Sharp SJ, Forouhi NG, Riboli E, Wareham NJ, InterAct Consortium

European Journal of Clinical Nutrition. Jan 2014

(DOI : 10.1038/ejcn.2014.249)

Dietary intakes of individual flavanols and flavonols are inversely associated with incident type 2 diabetes in European populations.

Zamora-Ros R, Forouhi NG, Sharp SJ, González CA, Buijsse B, Guevara M, van der Schouw YT, Amiano P, Boeing H, Bredsdorff L, Fagherazzi G, Feskens EJ, Franks PW, Grioni S, Katzke V, Key TJ, Khaw KT, Kühn T, Masala G, Mattiello A, Molina-Montes E, Nilsson PM, Overvad K, Perquier F, Redondo ML, Ricceri F, Rolandsson O, Romieu I, Roswall N, Scalbert A, Schulze M, Slimani N, Spijkerman AM, Tjonneland A, Tormo MJ, Touillaud M, Tumino R, van der A DL, van Woudenbergh GJ, Langenberg C, Riboli E, Wareham NJ

The Journal of nutrition. Dec 2013

(DOI : 10.3945/jn.113.184945)

Change in objectively measured physical activity during the transition to adolescence

Griffin SJ, Jones AP, Van Sluijs EM, Corder KL, Ekelund U, Sharp SJ

British Journal of Sports Medicine. Nov 2013

(DOI : 10.1136/bjsports-2013-093190)

Age at menarche and type 2 diabetes risk: the EPIC-InterAct study.

Elks CE, Ong KK, Scott RA, van der Schouw YT, Brand JS, Wark PA, Amiano P, Balkau B, Barricarte A, Boeing H, Fonseca-Nunes A, Franks PW, Grioni S, Halkjaer J, Kaaks R, Key TJ, Khaw KT, Mattiello A, Nilsson PM, Overvad K, Palli D, Quirós JR, Rinaldi S, Rolandsson O, Romieu I, Sacerdote C, Sánchez MJ, Spijkerman AM, Tjonneland A, Tormo MJ, Tumino R, van der A DL, Forouhi NG, Sharp SJ, Langenberg C, Riboli E, Wareham NJ

Diabetes care. Oct 2013

(DOI : 10.2337/dc13-0446)

Change in objectively measured physical activity during the transition to adolescence.

Corder KL, Sharp SJ, Atkin AJ, Griffin SJ, Jones AP, Ekelund U, Van Sluijs EM

British Journal of Sports Medicine. Oct 2013

(DOI : 10.1136/bjsports-2013-093190)

The association between dietary flavonoid and lignan intakes and incident type 2 diabetes in European populations: the EPIC-InterAct study.

Zamora-Ros R, Forouhi NG, Sharp SJ, González CA, Buijsse B, Guevara M, van der Schouw YT, Amiano P, Boeing H, Bredsdorff L, Clavel-Chapelon F, Fagherazzi G, Feskens EJ, Franks PW, Grioni S, Katzke V, Key TJ, Khaw KT, Kühn T, Masala G, Mattiello A, Molina-Montes E, Nilsson PM, Overvad K, Perquier F, Quirós JR, Romieu I, Sacerdote C, Scalbert A, Schulze M, Slimani N, Spijkerman AM, Tjonneland A, Tormo MJ, Tumino R, van der A DL, Langenberg C, Riboli E, Wareham NJ

Diabetes care. Oct 2013

(DOI : 10.2337/dc13-0877)

Estimated urinary sodium excretion and risk of heart failure in men and women in the EPIC-Norfolk study.

Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT

European journal of heart failure. Oct 2013

(DOI : 10.1002/ejhf.56)

Combined influence of epoch length, cut-point and bout duration on accelerometry-derived physical activity.

Orme M, Wijndaele K, Sharp SJ, Westgate K, Ekelund U, Brage S

The international journal of behavioral nutrition and physical activity. Oct 2013

(DOI : 10.1186/1479-5868-11-34)

Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study.

Langenberg C, Sharp SJ, Franks PW, Scott RA, Deloukas P, Forouhi NG, Froguel P, Groop LC, Hansen T, Palla L, Pedersen O, Schulze MB, Tormo MJ, Wheeler E, Agnoli C, Arriola L, Barricarte A, Boeing H, Clarke GM, Clavel-Chapelon F, Duell EJ, Fagherazzi G, Kaaks R, Kerrison ND, Key TJ, Khaw KT, Kröger J, Lajous M, Morris AP, Navarro C, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sánchez MJ, Slimani N, Spijkerman AM, Tumino R, van der A DL, van der Schouw YT, Barroso I, McCarthy MI, Riboli E, Wareham NJ

PLoS Medicine. Sep 2013

(DOI : 10.1371/journal.pmed.1001647)

Does early intensive multifactorial therapy reduce modelled cardiovascular risk in individuals with screen-detected diabetes? Results from the ADDITION-Europe cluster randomized trial.

Black JA, Sharp SJ, Wareham NJ, Sandbaek A, Rutten GE, Lauritzen T, Khunti K, Davies MJ, Borch-Johnsen K, Griffin SJ, Simmons RK

Diabetic medicine : a journal of the British Diabetic Association. Sep 2013

(DOI : 10.1111/dme.12410)

Effectiveness and equity impacts of town-wide cycling initiatives in England: A longitudinal, controlled natural experimental study.

Panter J, Goodman A, Ostro B, Sharp SJ

Social Science & Medicine. Sep 2013

Impact of personalised feedback about physical activity on change in objectively measured physical activity (the FAB study): a randomised controlled trial.

Griffin SJ, Van Sluijs EM, Corder KL, Godino JG, Marteau TM, Sharp SJ, Sutton S, Watkinson C

PLoS ONE. Sep 2013

Liver fat accumulation is associated with reduced hepatic insulin extraction and beta cell dysfunction in healthy older individuals.

Finucane FM, Sharp SJ, Hatunic M, Sleigh A, De Lucia Rolfe E, Aihie Sayer A, Cooper C, Griffin SJ, Wareham NJ

Diabetology & metabolic syndrome. Jul 2013

(DOI : 10.1186/1758-5996-6-43)

Increasing objectively measured sedentary time increases clustered cardiometabolic risk: a 6 year analysis of the ProActive study.

Wijndaele K, Orrow G, Ekelund U, Sharp SJ, Brage S, Griffin SJ, Simmons RK

Diabetologia. Jun 2013

(DOI : 10.1007/s00125-013-3102-y)

Dietary vitamin D intake and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition: the EPIC-InterAct study.

Abbas S, Linseisen J, Rohrmann S, Beulens JW, Buijsse B, Amiano P, Ardanaz E, Balkau B, Boeing H, Clavel-Chapelon F, Fagherazzi G, Franks PW, Gavrila D, Grioni S, Kaaks R, Key TJ, Khaw KT, Kühn T, Mattiello A, Molina-Montes E, Nilsson PM, Overvad K, Quirós JR, Rolandsson O, Sacerdote C, Saieva C, Slimani N, Sluijs I, Spijkerman AM, Tjonneland A, Tumino R, van der A DL, Zamora-Ros R, Sharp SJ, Langenberg C, Forouhi NG, Riboli E, Wareham NJ

European Journal of Clinical Nutrition. Jun 2013

(DOI : 10.1038/ejcn.2013.235)

Objectively measured physical activity in four-year-old British children: a cross-sectional analysis of activity patterns segmented across the day.

Hesketh KR, McMinn AM, Ekelund U, Sharp SJ, Collings PJ, Harvey NC, Godfrey KM, Inskip HM, Cooper C, Van Sluijs EM

The international journal of behavioral nutrition and physical activity. Jun 2013

(DOI : 10.1186/1479-5868-11-1)

Impact of personalised feedback about physical activity on change in objectively measured physical activity (the FAB study): a randomised controlled trial.

Godino JG, Watkinson C, Corder KL, Marteau TM, Sutton S, Sharp SJ, Griffin SJ, Van Sluijs EM

PLoS ONE. May 2013

(DOI : 10.1371/journal.pone.0075398)

Effectiveness and equity impacts of town-wide cycling initiatives in England: a longitudinal, controlled natural experimental study.

Goodman A, Panter J, Sharp SJ, Ogilvie D

Social science & medicine (1982). Apr 2013

(DOI : 10.1016/j.socscimed.2013.08.030)

Screening for type 2 diabetes and population mortality over 10 years - authors' reply.

Griffin SJ, Simmons RK, Sharp SJ

Lancet (London, England). Mar 2013

(DOI : 10.1016/S0140-6736(13)60668-6)

Self-rated health and type 2 diabetes risk in the European Prospective Investigation into Cancer and Nutrition-InterAct study: a case-cohort study.

Wennberg P, Rolandsson O, van der A DL, Spijkerman AM, Kaaks R, Boeing H, Feller S, Bergmann MM, Langenberg C, Sharp SJ, Forouhi N, Riboli E, Wareham NJ

BMJ Open. Mar 2013

(DOI : 10.1136/bmjopen-2012-002436)

Seropositivity and higher immunoglobulin g antibody levels against cytomegalovirus are associated with mortality in the population-based European prospective investigation of Cancer-Norfolk cohort.

Gkrania-Klotsas E, Langenberg C, Sharp SJ, Luben R, Khaw KT, Wareham NJ

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. Feb 2013

(DOI : 10.1093/cid/cit083)

Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals.

Finucane FM, Sharp SJ, Hatunic M, Sleigh A, De Lucia Rolfe E, Sayer AA, Cooper C, Griffin SJ, Savage DB, Wareham NJ

International journal of endocrinology. Jan 2013

(DOI : 10.1155/2013/870487)

Consumption of sweet beverages and type 2 diabetes incidence in European adults: results from EPIC-InterAct.

Romaguera D, Norat T, Wark PA, Vergnaud AC, Schulze MB, van Woudenbergh GJ, Drogan D, Amiano P, Molina-Montes E, Sánchez MJ, Balkau B, Barricarte A, Beulens JW, Clavel-Chapelon F, Crispim SP, Fagherazzi G, Franks PW, Grote VA, Huybrechts I, Kaaks R, Key TJ, Khaw KT, Nilsson P, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sieri S, Slimani N, Spijkerman AM, Tjonneland A, Tormo MJ, Tumino R, van den Berg SW, Wermeling PR, Zamara-Ros R, Feskens EJ, Langenberg C, Sharp SJ, Forouhi NG, Riboli E, Wareham NJ

Diabetologia. Dec 2012

(DOI : 10.1007/s00125-013-2899-8)

Age at menopause, reproductive life span, and type 2 diabetes risk: results from the EPIC-InterAct study.

Brand JS, van der Schouw YT, Onland-Moret NC, Sharp SJ, Ong KK, Khaw KT, Ardanaz E, Amiano P, Boeing H, Chirlaque MD, Clavel-Chapelon F, Crowe FL, de Lauzon-Guillain B, Duell EJ, Fagherazzi G, Franks PW, Grioni S, Groop LC, Kaaks R, Key TJ, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sánchez MJ, Slimani N, Teucher B, Tjonneland A, Tumino R, van der A DL, Feskens EJ, Langenberg C, Forouhi NG, Riboli E, Wareham NJ

Diabetes care. Dec 2012

(DOI : 10.2337/dc12-1020)

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dörr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson Å, Junttila J, Kääb S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Mateo Leach I, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, Müller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp SJ, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T, Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Järvelin MR, Jula A, Kähönen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtimäki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widén E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L, Erdmann J, Thompson JR, Pfeufer A, Sotoodehnia N, Newton-Cheh C, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ

Nature genetics. Dec 2012

(DOI : 10.1038/ng.2610)

Dietary glycemic index, glycemic load, and digestible carbohydrate intake are not associated with risk of type 2 diabetes in eight European countries.

Sluijs I, Beulens JW, van der Schouw YT, van der A DL, Buckland G, Kuijsten A, Schulze MB, Amiano P, Ardanaz E, Balkau B, Boeing H, Gavrila D, Grote VA, Key TJ, Li K, Nilsson P, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Roswall N, Sacerdote C, Sánchez MJ, Sieri S, Slimani N, Spijkerman AM, Tjønneland A, Tumino R, Sharp SJ, Langenberg C, Feskens EJ, Forouhi NG, Riboli E, Wareham NJ, InterAct Consortium

The Journal of nutrition. Nov 2012

(DOI : 10.3945/jn.112.165605)

The effects of vitamin D₂ or D₃ supplementation on glycaemic control and related metabolic parameters in people at risk of type 2 diabetes: protocol of a randomised double-blind placebo-controlled trial.

Menon RK, Rickard AP, Mannan N, Timms PM, Sharp SJ, Martineau A, Boucher BJ, Chowdhury TA, Griffiths CJ, Griffin SJ, Hitman GA, Forouhi NG

BMC Public Health. Nov 2012

(DOI : 10.1186/1471-2458-13-999)

The association between dietary energy density and type 2 diabetes in Europe: results from the EPIC-InterAct Study.

van den Berg SW, van der A DL, Spijkerman AM, van Woudenbergh GJ, Tijhuis MJ, Amiano P, Ardanaz E, Beulens JW, Boeing H, Clavel-Chapelon F, Crowe FL, de Lauzon-Guillain B, Fagherazzi G, Franks PW, Freisling H, Gonzalez C, Grioni S, Halkjaer J, Huerta JM, Huybrechts I, Kaaks R, Khaw KT, Masala G, Nilsson PM, Overvad K, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sánchez MJ, Schulze MB, Slimani N, Struijk EA, Tjonneland A, Tumino R, Sharp SJ, Langenberg C, Forouhi NG, Feskens EJ, Riboli E, Wareham NJ

PLoS ONE. Oct 2012

(DOI : 10.1371/journal.pone.0059947)

Higher immunoglobulin G antibody levels against cytomegalovirus are associated with incident ischemic heart disease in the population-based EPIC-Norfolk cohort.

Gkrania-Klotsas E, Langenberg C, Sharp SJ, Luben R, Khaw KT, Wareham NJ

The Journal of infectious diseases. Oct 2012

(DOI : 10.1093/infdis/jis620)

Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial.

Simmons RK, Echouffo-Tcheugui JB, Sharp SJ, Sargeant LA, Williams KM, Prevost AT, Kinmonth AL, Wareham NJ, Griffin SJ

Lancet (London, England). Oct 2012

(DOI : 10.1016/S0140-6736(12)61422-6)

Fruit and vegetable intake and type 2 diabetes: EPIC-InterAct prospective study and meta-analysis.

Cooper AJ, Forouhi NG, Ye Zheng, Buijsse B, Arriola L, Balkau B, Barricarte A, Beulens JW, Boeing H, Büchner FL, Dahm CC, de Lauzon-Guillain B, Fagherazzi G, Franks PW, Gonzalez C, Grioni S, Kaaks R, Key TJ, Masala G, Navarro C, Nilsson P, Overvad K, Panico S, Ramón Quirós J, Rolandsson O, Roswall N, Sacerdote C, Sánchez MJ, Slimani N, Sluijs I, Spijkerman AM, Teucher B, Tjonneland A, Tumino R, Sharp SJ, Langenberg C, Feskens EJ, Riboli E, Wareham NJ

European Journal of Clinical Nutrition. Aug 2012

(DOI : 10.1038/ejcn.2012.85)

Does early intensive multifactorial treatment reduce total cardiovascular burden in individuals with screen-detected diabetes? Findings from the ADDITION-Europe cluster-randomized trial.

Simmons RK, Sharp SJ, Sandbæk A, Borch-Johnsen K, Davies MJ, Khunti K, Lauritzen T, Rutten GE, van den Donk M, Wareham NJ, Griffin SJ

Diabetic medicine : a journal of the British Diabetic Association. Jul 2012

(DOI : 10.1111/j.1464-5491.2012.03759.x)

The amount and type of dairy product intake and incident type 2 diabetes: results from the EPIC-InterAct Study.

Sluijs I, Forouhi NG, Beulens JW, van der Schouw YT, Agnoli C, Arriola L, Balkau B, Barricarte A, Boeing H, Bueno-de-Mesquita HB, Clavel-Chapelon F, Crowe FL, de Lauzon-Guillain B, Drogan D, Franks PW, Gavrila D, Gonzalez C, Halkjaer J, Kaaks R, Moskal A, Nilsson P, Overvad K, Palli D, Panico S, Quirós JR, Ricceri F, Rinaldi S, Rolandsson O, Sacerdote C, Sánchez MJ, Slimani N, Spijkerman AM, Teucher B, Tjonneland A, Tormo MJ, Tumino R, van der A DL, Sharp SJ, Langenberg C, Feskens EJ, Riboli E, Wareham NJ

The American Journal of Clinical Nutrition. Jul 2012

(DOI : 10.3945/ajcn.111.021907)

Resting heart rate and incident heart failure in apparently healthy men and women in the EPIC-Norfolk study.

Pfister R, Michels G, Sharp SJ, Luben R, Wareham NJ, Khaw KT

European journal of heart failure. Jun 2012

(DOI : 10.1093/eurjhf/hfs104)

Lower educational level is a predictor of incident type 2 diabetes in European countries: the EPIC-InterAct study.

Sacerdote C, Ricceri F, Rolandsson O, Baldi I, Chirlaque MD, Feskens E, Bendinelli B, Ardanaz E, Arriola L, Balkau B, Bergmann M, Beulens JW, Boeing H, Clavel-Chapelon F, Crowe F, de Lauzon-Guillain B, Forouhi N, Franks PW, Gallo V, Gonzalez C, Halkjær J, Illner AK, Kaaks R, Key T, Khaw KT, Navarro C, Nilsson PM, Dal Ton SO, Overvad K, Pala V, Palli D, Panico S, Polidoro S, Quirós JR, Romieu I, Sánchez MJ, Slimani N, Sluijs I, Spijkerman A, Teucher B, Tjønneland A, Tumino R, van der A D, Vergnaud AC, Wennberg P, Sharp SJ, Langenberg C, Riboli E, Vineis P, Wareham NJ

International Journal of Epidemiology. Jun 2012

(DOI : 10.1093/ije/dys091)

A behavioral intervention in a cohort of Japanese-Brazilians at high cardiometabolic risk.

Almeida-Pititto Bd, Griffin SJ, Sharp SJ, Hirai AT, Gimeno SG, Ferreira SR

Revista de saude publica. Jun 2012

(DOI : 10.1590/s0034-89102012005000045)

The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study.

Scott RA, Langenberg C, Sharp SJ, Franks PW, Rolandsson O, Drogan D, van der Schouw YT, Ekelund U, Kerrison ND, Ardanaz E, Arriola L, Balkau B, Barricarte A, Barroso I, Bendinelli B, Beulens JW, Boeing H, de Lauzon-Guillain B, Deloukas P, Fagherazzi G, Gonzalez C, Griffin SJ, Groop LC, Halkjaer J, Huerta JM, Kaaks R, Khaw KT, Krogh V, Nilsson PM, Norat T, Overvad K, Panico S, Rodriguez-Suarez L, Romaguera D, Romieu I, Sacerdote C, Sánchez MJ, Spijkerman AM, Teucher B, Tjonneland A, Tumino R, van der A DL, Wark PA, McCarthy MI, Riboli E, Wareham NJ

Diabetologia. Jun 2012

(DOI : 10.1007/s00125-012-2715-x)

Cardiovascular risk reduction following diagnosis of diabetes by screening: 1-year results from the ADDITION-Cambridge trial cohort.

Charles M, Simmons RK, Williams KM, Roglic G, Sharp SJ, Kinmonth AL, Wareham NJ, Griffin SJ

The British journal of general practice : the journal of the Royal College of General Practitioners. Jun 2012

(DOI : 10.3399/bjgp12X649070)

Effect of communicating genetic and phenotypic risk for type 2 diabetes in combination with lifestyle advice on objectively measured physical activity: protocol of a randomised controlled trial.

Godino JG, Van Sluijs EM, Marteau TM, Sutton S, Sharp SJ, Griffin SJ

BMC Public Health. May 2012

(DOI : 10.1186/1471-2458-12-444)

The prospective association between total and type of fish intake and type 2 diabetes in 8 European countries: EPIC-InterAct Study.

Patel PS, Forouhi NG, Kuijsten A, Schulze MB, van Woudenbergh GJ, Ardanaz E, Amiano P, Arriola L, Balkau B, Barricarte A, Beulens JW, Boeing H, Buijsse B, Crowe FL, de Lauzon-Guillan B, Fagherazzi G, Franks PW, Gonzalez C, Grioni S, Halkjaer J, Huerta JM, Key TJ, Kühn T, Masala G, Nilsson P, Overvad K, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sánchez MJ, Schmidt EB, Slimani N, Spijkerman AM, Teucher B, Tjonneland A, Tormo MJ, Tumino R, van der A DL, van der Schouw YT, Sharp SJ, Langenberg C, Feskens EJ, Riboli E, Wareham NJ

The American Journal of Clinical Nutrition. May 2012

(DOI : 10.3945/ajcn.111.029314)

Association between dietary meat consumption and incident type 2 diabetes: the EPIC-InterAct study.

Bendinelli B, Palli D, Masala G, Sharp SJ, Schulze MB, Guevara M, van der AD, Sera F, Amiano P, Balkau B, Barricarte A, Boeing H, Crowe FL, Dahm CC, Dalmeijer G, de Lauzon-Guillain B, Egeberg R, Fagherazzi G, Franks PW, Krogh V, Huerta JM, Jakszyn P, Khaw KT, Li K, Mattiello A, Nilsson PM, Overvad K, Ricceri F, Rolandsson O, Sánchez MJ, Slimani N, Sluijs I, Spijkerman AM, Teucher B, Tjonneland A, Tumino R, van den Berg SW, Forouhi NG, Langenberg C, Feskens EJ, Riboli E, Wareham NJ

Diabetologia. May 2012

(DOI : 10.1007/s00125-012-2718-7)

A prospective study of the association between quantity and variety of fruit and vegetable intake and incident type 2 diabetes.

Cooper AJ, Sharp SJ, Lentjes MA, Luben RN, Khaw KT, Wareham NJ, Forouhi NG

Diabetes care. Apr 2012

(DOI : 10.2337/dc11-2388)

Alcohol consumption and risk of type 2 diabetes in European men and women: influence of beverage type and body size The EPIC-InterAct study.

Beulens JW, van der Schouw YT, Bergmann MM, Rohrmann S, Schulze MB, Buijsse B, Grobbee DE, Arriola L, Cauchi S, Tormo MJ, Allen NE, van der A DL, Balkau B, Boeing H, Clavel-Chapelon F, de Lauzon-Guillan B, Franks P, Froguel P, Gonzales C, Halkjaer J, Huerta JM, Kaaks R, Key TJ, Khaw KT, Krogh V, Molina-Montes E, Nilsson P, Overvad K, Palli D, Panico S, Ramón Quirós J, Rolandsson O, Ronaldsson O, Romieu I, Romaguera D, Sacerdote C, Sánchez MJ, Spijkerman AM, Teucher B, Tjonneland A, Tumino R, Sharp SJ, Forouhi NG, Langenberg C, Feskens EJ, Riboli E, Wareham NJ

Journal of internal medicine. Feb 2012

(DOI : 10.1111/j.1365-2796.2012.02532.x)

Prediction of measured weight from self-reported weight was not improved after stratification by body mass index.

May AM, Barnes DR, Forouhi NG, Luben R, Khaw KT, Wareham NJ, Peeters PH, Sharp SJ

Obesity (Silver Spring, Md.). Jan 2012

(DOI : 10.1002/oby.20141)

Differential white blood cell count and incident heart failure in men and women in the EPIC-Norfolk study.

Pfister R, Sharp SJ, Luben R, Wareham NJ, Khaw KT

European heart journal. Dec 2011

(DOI : 10.1093/eurheartj/ehr457)

Prediction of childhood obesity by infancy weight gain: an individual-level meta-analysis.

Druet C, Stettler N, Sharp SJ, Simmons RK, Cooper C, Smith GD, Ekelund U, Lévy-Marchal C, Järvelin MR, Kuh D, Ong KK

Paediatric and perinatal epidemiology. Dec 2011

(DOI : 10.1111/j.1365-3016.2011.01213.x)

Physical activity reduces the risk of incident type 2 diabetes in general and in abdominally lean and obese men and women: the EPIC-InterAct Study.

Ekelund U, Palla L, Brage S, Franks PW, Peters T, Balkau B, Diaz MJ, Huerta JM, Agnoli C, Arriola L, Ardanaz E, Boeing H, Clavel-Chapelon F, Crowe F, Fagherazzi G, Groop L, Føns Johnsen N, Kaaks R, Khaw KT, Key TJ, de Lauzon-Guillain B, May A, Monninkhof E, Navarro C, Nilsson P, Nautrup Østergaard J, Norat T, Overvad K, Palli D, Panico S, Redondo ML, Ricceri F, Rolandsson O, Romaguera D, Romieu I, Sánchez Pérez MJ, Slimani N, Spijkerman A, Teucher B, Tjonneland A, Travier N, Tumino R, Vos W, Vigl M, Sharp SJ, Langenberg C, Forouhi N, Riboli E, Feskens E, Wareham NJ

Diabetologia. Nov 2011

(DOI : 10.1007/s00125-012-2532-2)

Tea consumption and incidence of type 2 diabetes in Europe: the EPIC-InterAct case-cohort study.

van Woudenbergh GJ, Kuijsten A, Drogan D, van der A DL, Romaguera D, Ardanaz E, Amiano P, Barricarte A, Beulens JW, Boeing H, Bueno-de-Mesquita HB, Dahm CC, Chirlaque MD, Clavel F, Crowe FL, Eomois PP, Fagherazzi G, Franks PW, Halkjaer J, Khaw KT, Masala G, Mattiello A, Nilsson P, Overvad K, Ramón Quirós J, Rolandsson O, Romieu I, Sacerdote C, Sánchez MJ, Schulze MB, Slimani N, Sluijs I, Spijkerman AM, Tagliabue G, Tjønneland A, Tumino R, Forouhi NG, Sharp SJ, Langenberg C, Feskens EJ, Riboli E, Wareham NJ

PLoS ONE. Oct 2011

(DOI : 10.1371/journal.pone.0036910)

Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study.

Langenberg C, Sharp SJ, Schulze MB, Rolandsson O, Overvad K, Forouhi NG, Spranger J, Drogan D, Huerta JM, Arriola L, de Lauzon-Guillan B, Tormo MJ, Ardanaz E, Balkau B, Beulens JW, Boeing H, Bueno-de-Mesquita HB, Clavel-Chapelon F, Crowe FL, Franks PW, González CA, Grioni S, Halkjaer J, Hallmans G, Kaaks R, Kerrison ND, Key TJ, Khaw KT, Mattiello A, Nilsson P, Norat T, Palla L, Palli D, Panico S, Quirós JR, Romaguera D, Romieu I, Sacerdote C, Sánchez MJ, Slimani N, Sluijs I, Spijkerman AM, Teucher B, Tjonneland A, Tumino R, van der A DL, van der Schouw YT, Feskens EJ, Riboli E, Wareham NJ

PLoS Medicine. Oct 2011

(DOI : 10.1371/journal.pmed.1001230)

Variability in the heritability of body mass index: a systematic review and meta-regression.

Elks CE, den Hoed M, Zhao JH, Sharp SJ, Wareham NJ, Loos RJ, Ong KK

Frontiers in endocrinology. Oct 2011

(DOI : 10.3389/fendo.2012.00029)

The association between prior infection with five serotypes of Coxsackievirus B and incident type 2 diabetes mellitus in the EPIC-Norfolk study.

Gkrania-Klotsas E, Langenberg C, Tauriainen S, Sharp SJ, Luben R, Forouhi NG, Khaw KT, Hyöty H, Wareham NJ

Diabetologia. Oct 2011

(DOI : 10.1007/s00125-011-2443-7)

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems S, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin SJ, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, Van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hillman DR, Hingorani AD, Hui J, Hung J, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sigurðsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Serrano-Rios M, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pramstaller PP, Wright AF, Stumvoll M, Hamsten A, Buchanan TA, Valle TT, Rotter JI, Penninx BW, Boomsma DI, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Järvelin MR, Peltonen L, Mooser V, Sladek R, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Chasman DI, Johansen CT, Fouchier SW, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Feitosa MF, Orho-Melander M, Melander O, Li X, Li M, Cho YS, Go MJ, Kim YJ, Lee JY, Park T, Kim K, Sim X, Ong RT, Croteau-Chonka DC, Lange LA, Smith JD, Ziegler A, Zhang W, Zee RY, Whitfield JB, Thompson JR, Surakka I, Spector TD, Smit JH, Sinisalo J, Scott J, Saharinen J, Sabatti C, Rose LM, Roberts R, Rieder M, Parker AN, Pare G, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, McArdle W, Masson D, Martin NG, Marroni F, Lucas G, Luben R, Lokki ML, Lettre G, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, König IR, Khaw KT, Kaplan LM, Johansson Å, Janssens AC, Igl W, Hovingh GK, Hengstenberg C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Groop LC, Gonzalez E, Freimer NB, Erdmann J, Ejebe KG, Döring A, Dominiczak AF, Demissie S, Deloukas P, de Faire U, Crawford G, Chen YD, Caulfield MJ, Boekholdt SM, Assimes TL, Quertermous T, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Taylor HA, Gabriel SB, Holm H, Gudnason V, Krauss RM, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Strachan DP, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, Kathiresan S

PLoS genetics. Sep 2011

(DOI : 10.1371/journal.pgen.1002607)

A genome-wide association search for type 2 diabetes genes in African Americans.

Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, Lu L, Ziegler JT, Sale MM, Divers J, Shriner D, Adeyemo A, Rotimi CN, Ng MC, Langefeld CD, Freedman BI, Bowden DW, Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin SJ, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, Van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Johnson T, Elliott P, Rybin D, Henneman P, Dehghan A, Hottenga JJ, Song K, Goel A, Egan JM, Lajunen T, Doney A, Kanoni S, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hicks AA, Hillman DR, Hingorani AD, Hui J, Hung J, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Oostra BA, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Rios M, Lind L, Palmer LJ, Franks PW, Ebrahim S, Marmot M, Kao WH, Pramstaller PP, Wright AF, Stumvoll M, Hamsten A, Buchanan TA, Valle TT, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Ferrucci L, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Järvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Sladek R

PLoS ONE. Aug 2011

(DOI : 10.1371/journal.pone.0029202)

Validity of a short questionnaire to assess physical activity in 10 European countries.

Peters T, Brage S, Westgate K, Franks PW, Gradmark A, Tormo Diaz MJ, Huerta JM, Bendinelli B, Vigl M, Boeing H, Wendel-Vos W, Spijkerman A, Benjaminsen-Borch K, Valanou E, de Lauzon Guillain B, Clavel-Chapelon F, Sharp SJ, Kerrison N, Langenberg C, Arriola L, Barricarte A, Gonzales C, Grioni S, Kaaks R, Key T, Khaw KT, May A, Nilsson P, Norat T, Overvad K, Palli D, Panico S, Ramón Quirós J, Ricceri F, Sánchez MJ, Slimani N, Tjonneland A, Tumino R, Feskins E, Riboli E, Ekelund U, Wareham NJ

European Journal of Epidemiology. Aug 2011

(DOI : 10.1007/s10654-011-9625-y)

Effect of early intensive multifactorial therapy on 5-year cardiovascular outcomes in individuals with type 2 diabetes detected by screening (ADDITION-Europe): a cluster-randomised trial.

Griffin SJ, Borch-Johnsen K, Davies MJ, Khunti K, Rutten GE, Sandbæk A, Sharp SJ, Simmons RK, van den Donk M, Wareham NJ, Lauritzen T

Lancet (London, England). Jun 2011

(DOI : 10.1016/S0140-6736(11)60698-3)

The aetiology of symptomatic gallstones quantification of the effects of obesity, alcohol and serum lipids on risk. Epidemiological and biomarker data from a UK prospective cohort study (EPIC-Norfolk).

Banim PJ, Luben RN, Bulluck H, Sharp SJ, Wareham NJ, Khaw KT, Hart AR

European journal of gastroenterology & hepatology. May 2011

(DOI : 10.1097/MEG.0b013e3283477cc9)

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children.

Barker A, Sharp SJ, Timpson NJ, Bouatia-Naji N, Warrington NM, Kanoni S, Beilin LJ, Brage S, Deloukas P, Evans DM, Grontved A, Hassanali N, Lawlor DA, Lecoeur C, Loos RJ, Lye SJ, McCarthy MI, Mori TA, Ndiaye NC, Newnham JP, Ntalla I, Pennell CE, St Pourcain B, Prokopenko I, Ring SM, Sattar N, Visvikis-Siest S, Dedoussis GV, Palmer LJ, Froguel P, Smith GD, Ekelund U, Wareham NJ, Langenberg C

Diabetes. Apr 2011

(DOI : 10.2337/db10-1575)

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.

Kilpeläinen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, Ahmad T, Mora S, Kaakinen M, Sandholt CH, Holzapfel C, Autenrieth CS, Hyppönen E, Cauchi S, He M, Kutalik Z, Kumari M, Stančáková A, Meidtner K, Balkau B, Tan JT, Mangino M, Timpson NJ, Song Y, Zillikens MC, Jablonski KA, Garcia ME, Johansson S, Bragg-Gresham JL, Wu Y, Van Vliet-Ostaptchouk JV, Onland-Moret NC, Zimmermann E, Rivera NV, Tanaka T, Stringham HM, Silbernagel G, Kanoni S, Feitosa MF, Snitker S, Ruiz JR, Metter J, Larrad MT, Atalay M, Hakanen M, Amin N, Cavalcanti-Proença C, Grøntved A, Hallmans G, Jansson JO, Kuusisto J, Kähönen M, Lutsey PL, Nolan JJ, Palla L, Pedersen O, Pérusse L, Renstrom F, Scott RA, Shungin D, Sovio U, Tammelin TH, Rönnemaa T, Lakka TA, Uusitupa M, Rios MS, Ferrucci L, Bouchard C, Meirhaeghe A, Fu M, Walker M, Borecki IB, Dedoussis GV, Fritsche A, Ohlsson C, Boehnke M, Bandinelli S, van Duijn CM, Ebrahim S, Lawlor DA, Gudnason V, Harris TB, Sørensen TI, Mohlke KL, Hofman A, Uitterlinden AG, Tuomilehto J, Lehtimäki T, Raitakari O, Isomaa B, Njølstad PR, Florez JC, Liu S, Ness A, Spector TD, Tai ES, Froguel P, Boeing H, Laakso M, Marmot M, Bergmann S, Power C, Khaw KT, Chasman D, Ridker P, Hansen T, Monda KL, Illig T, Järvelin MR, Wareham NJ, Hu FB, Groop LC, Orho-Melander M, Ekelund U, Franks PW, Loos RJ

PLoS Medicine. Apr 2011

(DOI : 10.1371/journal.pmed.1001116)

Physical activity and gain in abdominal adiposity and body weight: prospective cohort study in 288,498 men and women.

Ekelund U, Besson H, Luan J, May AM, Sharp SJ, Brage S, Travier N, Agudo A, Slimani N, Rinaldi S, Jenab M, Norat T, Mouw T, Rohrmann S, Kaaks R, Bergmann MM, Boeing H, Clavel-Chapelon F, Boutron-Ruault MC, Overvad K, Jakobsen MU, Johnsen NF, Halkjaer J, González CA, Rodriguez L, Sánchez MJ, Arriola L, Barricarte A, Navarro C, Key TJ, Spencer EA, Orfanos P, Naska A, Trichopoulou A, Manjer J, Lund E, Palli D, Pala V, Vineis P, Mattiello A, Tumino R, Bueno-de-Mesquita HB, van den Berg SW, Odysseos AD, Riboli E, Wareham NJ, Peeters PH

The American Journal of Clinical Nutrition. Feb 2011

(DOI : 10.3945/ajcn.110.006593)

Plasma vitamin C predicts incident heart failure in men and women in European Prospective Investigation into Cancer and Nutrition-Norfolk prospective study.

Pfister R, Sharp SJ, Luben R, Wareham NJ, Khaw KT

American heart journal. Feb 2011

(DOI : 10.1016/j.ahj.2011.05.007)

Television viewing and incident cardiovascular disease: prospective associations and mediation analysis in the EPIC Norfolk Study.

Wijndaele K, Brage S, Besson H, Khaw KT, Sharp SJ, Luben R, Bhaniani A, Wareham NJ, Ekelund U

PLoS ONE. Dec 2010

(DOI : 10.1371/journal.pone.0020058)

A proposed method of bias adjustment for meta-analyses of published observational studies.

Thompson S, Ekelund U, Jebb S, Lindroos AK, Mander A, Sharp SJ, Turner R, Wilks D

International Journal of Epidemiology. Dec 2010

(DOI : 10.1093/ije/dyq248)

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study.

Langenberg C, Sharp SJ, Forouhi NG, Franks PW, Schulze MB, Kerrison N, Ekelund U, Barroso I, Panico S, Tormo MJ, Spranger J, Griffin SJ, van der Schouw YT, Amiano P, Ardanaz E, Arriola L, Balkau B, Barricarte A, Beulens JW, Boeing H, Bueno-de-Mesquita HB, Buijsse B, Chirlaque Lopez MD, Clavel-Chapelon F, Crowe FL, de Lauzon-Guillan B, Deloukas P, Dorronsoro M, Drogan D, Froguel P, Gonzalez C, Grioni S, Groop L, Groves C, Hainaut P, Halkjaer J, Hallmans G, Hansen T, Huerta Castaño JM, Kaaks R, Key TJ, Khaw KT, Koulman A, Mattiello A, Navarro C, Nilsson P, Norat T, Overvad K, Palla L, Palli D, Pedersen O, Peeters PH, Quirós JR, Ramachandran A, Rodriguez-Suarez L, Rolandsson O, Romaguera D, Romieu I, Sacerdote C, Sánchez MJ, Sandbaek A, Slimani N, Sluijs I, Spijkerman AM, Teucher B, Tjonneland A, Tumino R, van der A DL, Verschuren WM, Tuomilehto J, Feskens E, McCarthy M, Riboli E, Wareham NJ

Diabetologia. Dec 2010

(DOI : 10.1007/s00125-011-2182-9)

Mendelian Randomisation Study of Childhood BMI and Early Menarche.

Mumby HS, Elks CE, Li S, Sharp SJ, Khaw KT, Luben RN, Wareham NJ, Loos RJ, Ong KK

Journal of Obesity. Dec 2010

(DOI : 10.1155/2011/180729)

No evidence of an increased mortality risk associated with low levels of glycated haemoglobin in a non-diabetic UK population.

Pfister R, Sharp SJ, Luben R, Khaw KT, Wareham NJ

Diabetologia. Oct 2010

(DOI : 10.1007/s00125-011-2162-0)

Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: a pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort.

Patel PS, Sharp SJ, Jansen E, Luben RN, Khaw KT, Wareham NJ, Forouhi NG

The American Journal of Clinical Nutrition. Sep 2010

(DOI : 10.3945/ajcn.2010.29182)

School-level correlates of physical activity intensity in 10-year-old children.

Van Sluijs EM, Jones NR, Jones AP, Sharp SJ, Harrison F, Griffin SJ

International journal of pediatric obesity : IJPO : an official journal of the International Association for the Study of Obesity. Sep 2010

(DOI : 10.3109/17477166.2010.518239)

School-level correlates of physical activity intensity in 10-year old children

Griffin SJ, Jones AP, Van Sluijs EM, Harrison F, Jones N, Sharp SJ

International Journal of Pediatric Obesity. Sep 2010

(DOI : 10.3109/17477166.2010.518239)

A simple risk score using routine data for predicting cardiovascular disease in primary care.

Chamnan P, Simmons RK, Hori H, Sharp SJ, Khaw KT, Wareham NJ, Griffin SJ

The British journal of general practice : the journal of the Royal College of General Practitioners. Sep 2010

(DOI : 10.3399/bjgp10X515098)

The contribution of prenatal environment and genetic factors to the association between birth weight and adult grip strength.

Ridgway CL, Sharp SJ, Derom C, Beunen G, Fagard R, Vlietinck R, Ekelund U, Loos RJ

PLoS ONE. Sep 2010

(DOI : 10.1371/journal.pone.0017955)

Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.

den Hoed M, Ekelund U, Brage S, Grontved A, Zhao JH, Sharp SJ, Ong KK, Wareham NJ, Loos RJ

Diabetes. Aug 2010

(DOI : 10.2337/db10-0370)

Objectively measured physical activity and fat mass in children: a bias-adjusted meta-analysis of prospective studies.

Wilks DC, Sharp SJ, Ekelund U, Thompson SG, Mander AP, Turner RM, Jebb SA, Lindroos AK

PLoS ONE. Aug 2010

(DOI : 10.1371/journal.pone.0017205)

Does birth weight influence physical activity in youth? A combined analysis of four studies using objectively measured physical activity.

Ridgway CL, Brage S, Sharp SJ, Corder K, Westgate K, Van Sluijs EM, Goodyer IM, Hallal PC, Anderssen SA, Sardinha LB, Andersen LB, Ekelund U

PLoS ONE. Aug 2010

(DOI : 10.1371/journal.pone.0016125)

An investigation of patterns of children's sedentary and vigorous physical activity throughout the week.

Steele RM, Van Sluijs EM, Sharp SJ, Landsbaugh JR, Ekelund U, Griffin SJ

The international journal of behavioral nutrition and physical activity. Jul 2010

(DOI : 10.1186/1479-5868-7-88)

Television viewing time independently predicts all-cause and cardiovascular mortality: the EPIC Norfolk study.

Wijndaele K, Brage S, Besson H, Khaw KT, Sharp SJ, Luben R, Wareham NJ, Ekelund U

International Journal of Epidemiology. Jun 2010

(DOI : 10.1093/ije/dyq105)

Differential white blood cell count and type 2 diabetes: systematic review and meta-analysis of cross-sectional and prospective studies.

Gkrania-Klotsas E, Ye Zheng, Cooper AJ, Sharp SJ, Luben R, Biggs ML, Chen LK, Gokulakrishnan K, Hanefeld M, Ingelsson E, Lai WA, Lin SY, Lind L, Lohsoonthorn V, Mohan V, Muscari A, Nilsson G, Ohrvik J, Chao Qiang J, Jenny NS, Tamakoshi K, Temelkova-Kurktschiev T, Wang YY, Yajnik CS, Zoli M, Khaw KT, Forouhi NG, Wareham NJ, Langenberg C

PLoS ONE. Jun 2010

(DOI : 10.1371/journal.pone.0013405)

Challenges in the use of literature-based meta-analysis to examine gene-environment interactions.

Palla L, Higgins JP, Wareham NJ, Sharp SJ

American Journal of Epidemiology. Apr 2010

(DOI : 10.1093/aje/kwq051)

A novel school-based intervention to improve nutrition knowledge in children: cluster randomised controlled trial

Forouhi NG, Lakshman R, Ong KK, Sharp SJ

BMC Public Health. Mar 2010

(DOI : 10.1186/1471-2458-10-123)

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.

Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp SJ, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, Bergmann A, Berne C, Boehnke M, Bonnycastle LL, Bornstein SR, Buchanan TA, Bumpstead SJ, Böttcher Y, Chines P, Collins FS, Cooper CC, Dennison EM, Erdos MR, Ferrannini E, Fox CS, Graessler J, Hao K, Isomaa B, Jameson KA, Kovacs P, Kuusisto J, Laakso M, Ladenvall C, Mohlke KL, Morken MA, Narisu N, Nathan DM, Pascoe L, Payne F, Petrie JR, Sayer AA, Schwarz PE, Scott LJ, Stringham HM, Stumvoll M, Swift AJ, Syvänen AC, Tuomi T, Tuomilehto J, Tönjes A, Valle TT, Williams GH, Lind L, Barroso I, Quertermous T, Walker M, Wareham NJ, Meigs JB, McCarthy MI, Groop L, Watanabe RM, Florez JC

Diabetes. Feb 2010

(DOI : 10.2337/db09-1568)

Physical activity reduces the risk of symptomatic gallstones: a prospective cohort study.

Banim PJ, Luben RN, Wareham NJ, Sharp SJ, Khaw KT, Hart AR

European journal of gastroenterology & hepatology. Feb 2010

(DOI : 10.1097/MEG.0b013e32833732c3)

A multilevel linear mixed model of the association between candidate genes and weight and body mass index using the Framingham longitudinal family data.

Luan J, Kerner B, Zhao JH, Loos RJ, Sharp SJ, Muthén BO, Wareham NJ

BMC proceedings. Dec 2009

(DOI : 10.1186/1753-6561-3-s7-s115)

Early age at menarche associated with cardiovascular disease and mortality.

Lakshman R, Forouhi NG, Sharp SJ, Luben R, Bingham SA, Khaw KT, Wareham NJ, Ong KK

The Journal of clinical endocrinology and metabolism. Nov 2009

(DOI : 10.1210/jc.2009-1789)

Analysis of TBC1D4 in patients with severe insulin resistance.

Dash S, Langenberg C, Fawcett KA, Semple RK, Romeo S, Sharp SJ, Sano H, Lienhard GE, Rochford JJ, Howlett T, Massoud AF, Hindmarsh P, Howell SJ, Wilkinson RJ, Lyssenko V, Groop L, Baroni MG, Barroso I, Wareham NJ, O'Rahilly S, Savage DB

Diabetologia. Oct 2009

(DOI : 10.1007/s00125-010-1724-x)

Dietary fat intake and subsequent weight change in adults: results from the European Prospective Investigation into Cancer and Nutrition cohorts.

Forouhi NG, Sharp SJ, Du H, van der A DL, Halkjaer J, Schulze MB, Tjønneland A, Overvad K, Jakobsen MU, Boeing H, Buijsse B, Palli D, Masala G, Feskens EJ, Sørensen TI, Wareham NJ

The American Journal of Clinical Nutrition. Oct 2009

(DOI : 10.3945/ajcn.2009.27828)

Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.

Elks CE, Loos RJ, Sharp SJ, Langenberg C, Ring SM, Timpson NJ, Ness AR, Davey Smith G, Dunger DB, Wareham NJ, Ong KK

PLoS Medicine. Oct 2009

(DOI : 10.1371/journal.pmed.1000284)

Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women.

De Lucia Rolfe E, Sleigh A, Finucane FM, Brage S, Stolk RP, Cooper C, Sharp SJ, Wareham NJ, Ong KK

Obesity (Silver Spring, Md.). Sep 2009

(DOI : 10.1038/oby.2009.309)

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, Perry JR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day IN, de Geus EJ, Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han X, Hartikainen AL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hillman DR, Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PR, Jørgensen T, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McCulloch LJ, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S, Naitza S, Narisu N, Neville MJ, Oostra BA, Orrù M, Pakyz R, Palmer CN, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rathmann W, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Roden M, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sigurethsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Thorand B, Tichet J, Tönjes A, Tuomi T, Uitterlinden AG, van Dijk KW, van Hoek M, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Walters GB, Ward KL, Watkins H, Weedon MN, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zeggini E, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Rios M, Morris AD, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pankow JS, Sampson MJ, Kuusisto J, Laakso M, Hansen T, Pedersen O, Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright AF, Stumvoll M, Campbell H, Wilson JF, Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, Altshuler D, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Järvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ, Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI, Florez JC, Barroso I

Nature genetics. Aug 2009

(DOI : 10.1038/ng.520)

The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial.

Finucane FM, Sharp SJ, Purslow LR, Horton K, Horton J, Savage DB, Brage S, Besson H, De Lucia Rolfe E, Sleigh A, Martin HJ, Aihie Sayer A, Cooper C, Ekelund U, Griffin SJ, Wareham NJ

Diabetologia. Aug 2009

(DOI : 10.1007/s00125-009-1641-z)

Association between type of dietary fish and seafood intake and the risk of incident type 2 diabetes: the European prospective investigation of cancer (EPIC)-Norfolk cohort study.

Patel PS, Sharp SJ, Luben RN, Khaw KT, Bingham SA, Wareham NJ, Forouhi NG

Diabetes care. Jul 2009

(DOI : 10.2337/dc09-0116)

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P, Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL, Manning AK, Luan J, Stringham HM, Prokopenko I, Johnson T, Grarup N, Boesgaard TW, Lecoeur C, Shrader P, O'Connell J, Ingelsson E, Couper DJ, Rice K, Song K, Andreasen CH, Dina C, Köttgen A, Le Bacquer O, Pattou F, Taneera J, Steinthorsdottir V, Rybin D, Ardlie K, Sampson M, Qi L, van Hoek M, Weedon MN, Aulchenko YS, Voight BF, Grallert H, Balkau B, Bergman RN, Bielinski SJ, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Buchanan TA, Bumpstead SJ, Cavalcanti-Proença C, Charpentier G, Chen YD, Chines PS, Collins FS, Cornelis M, J Crawford G, Delplanque J, Doney A, Egan JM, Erdos MR, Firmann M, Forouhi NG, Fox CS, Goodarzi MO, Graessler J, Hingorani A, Isomaa B, Jørgensen T, Kivimaki M, Kovacs P, Krohn K, Kumari M, Lauritzen T, Lévy-Marchal C, Mayor V, McAteer JB, Meyre D, Mitchell BD, Mohlke KL, Morken MA, Narisu N, Palmer CN, Pakyz R, Pascoe L, Payne F, Pearson D, Rathmann W, Sandbaek A, Sayer AA, Scott LJ, Sharp SJ, Sijbrands E, Singleton A, Siscovick DS, Smith NL, Sparsø T, Swift AJ, Syddall H, Thorleifsson G, Tönjes A, Tuomi T, Tuomilehto J, Valle TT, Waeber G, Walley A, Waterworth DM, Zeggini E, Zhao JH, Illig T, Wichmann HE, Wilson JF, van Duijn C, Hu FB, Morris AD, Frayling TM, Hattersley AT, Thorsteinsdottir U, Stefansson K, Nilsson P, Syvänen AC, Shuldiner AR, Walker M, Bornstein SR, Schwarz P, Williams GH, Nathan DM, Kuusisto J, Laakso M, Cooper C, Marmot M, Ferrucci L, Mooser V, Stumvoll M, Loos RJ, Altshuler D, Psaty BM, Rotter JI, Boerwinkle E, Hansen T, Pedersen O, Florez JC, McCarthy MI, Boehnke M, Barroso I, Sladek R, Froguel P, Meigs JB, Groop L, Wareham NJ, Watanabe RM

Nature genetics. Jul 2009

(DOI : 10.1038/ng.521)

Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals.

Finucane FM, Luan J, Wareham NJ, Sharp SJ, O'Rahilly S, Balkau B, Flyvbjerg A, Walker M, Højlund K, Nolan JJ, Savage DB

Diabetologia. Jun 2009

(DOI : 10.1007/s00125-009-1508-3)

Birth size, infant weight gain, and motor development influence adult physical performance.

Ridgway CL, Ong KK, Tammelin T, Sharp SJ, Ekelund U, Järvelin MR

Medicine and Science in Sports and Exercise. May 2009

(DOI : 10.1249/MSS.0b013e31819794ab)

Fruit and vegetable intakes and subsequent changes in body weight in European populations: results from the project on Diet, Obesity, and Genes (DiOGenes).

Buijsse B, Feskens EJ, Schulze MB, Forouhi NG, Wareham NJ, Sharp SJ, Palli D, Tognon G, Halkjaer J, Tjønneland A, Jakobsen MU, Overvad K, van der A DL, Du H, Sørensen TI, Boeing H

The American Journal of Clinical Nutrition. May 2009

(DOI : 10.3945/ajcn.2008.27394)

Infant motor development predicts sports participation at age 14 years: northern Finland birth cohort of 1966.

Ridgway CL, Ong KK, Tammelin TH, Sharp SJ, Ekelund U, Järvelin MR

PLoS ONE. May 2009

(DOI : 10.1371/journal.pone.0006837)

Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial.

Finucane FM, Horton J, Purslow LR, Savage DB, Brage S, Besson H, Horton K, Rolfe Ede L, Sleigh A, Sharp SJ, Martin HJ, Sayer AA, Cooper C, Ekelund U, Griffin SJ, Wareham NJ

BMC endocrine disorders. Mar 2009

(DOI : 10.1186/1472-6823-9-15)

A cross-sectional analysis of physical activity and obesity indicators in European participants of the EPIC-PANACEA study.

Besson H, Ekelund U, Luan J, May AM, Sharp SJ, Travier N, Agudo A, Slimani N, Rinaldi S, Jenab M, Norat T, Mouw T, Rohrmann S, Kaaks R, Bergmann M, Boeing H, Clavel-Chapelon F, Boutron-Ruault MC, Overvad K, Andreasen EL, Johnsen NF, Halkjaer J, Gonzalez C, Rodriguez L, Sánchez MJ, Arriola L, Barricarte A, Navarro C, Key TJ, Spencer EA, Orfanos P, Naska A, Trichopoulou A, Manjer J, Wirfält E, Lund E, Palli D, Agnoli C, Vineis P, Panico S, Tumino R, Bueno-de-Mesquita HB, van den Berg SW, Odysseos AD, Riboli E, Wareham NJ, Peeters PH

International Journal of Obesity. Feb 2009

(DOI : 10.1038/ijo.2009.25)

A novel school-based intervention to improve nutrition knowledge in children: cluster randomised controlled trial.

Lakshman R, Sharp SJ, Ong KK, Forouhi NG

BMC Public Health. Feb 2009

(DOI : 10.1186/1471-2458-10-123)

Cardiovascular risk assessment scores for people with diabetes: a systematic review.

Chamnan P, Simmons RK, Sharp SJ, Griffin SJ, Wareham NJ

Diabetologia. Feb 2009

(DOI : 10.1007/s00125-009-1454-0)

Television viewing time and weight gain in colorectal cancer survivors: a prospective population-based study.

Wijndaele K, Lynch BM, Owen N, Dunstan DW, Sharp SJ, Aitken JF

Cancer causes & control : CCC. Jan 2009

(DOI : 10.1007/s10552-009-9356-5)

Association of C-reactive protein with type 2 diabetes: prospective analysis and meta-analysis.

Lee CC, Adler AI, Sandhu MS, Sharp SJ, Forouhi NG, Erqou S, Luben R, Bingham S, Khaw KT, Wareham NJ

Diabetologia. Nov 2008

(DOI : 10.1007/s00125-009-1338-3)

Time spent being sedentary and weight gain in healthy adults: reverse or bidirectional causality?

Ekelund U, Brage S, Besson H, Sharp SJ, Wareham NJ

The American Journal of Clinical Nutrition. Sep 2008

(DOI : 10.1093/ajcn/88.3.612)

Evaluation of the Framingham risk score in the European Prospective Investigation of Cancer-Norfolk cohort: does adding glycated hemoglobin improve the prediction of coronary heart disease events?

Simmons RK, Sharp SJ, Boekholdt SM, Sargeant LA, Khaw KT, Wareham NJ, Griffin SJ

Archives of internal medicine. Jun 2008

(DOI : 10.1001/archinte.168.11.1209)

Variants in MTNR1B influence fasting glucose levels.

Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp SJ, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Järvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR

Nature genetics. Jun 2008

(DOI : 10.1038/ng.290)

Increase in physical activity energy expenditure is associated with reduced metabolic risk independent of change in fatness and fitness.

Ekelund U, Franks PW, Sharp SJ, Brage S, Wareham NJ

Diabetes care. May 2007

(DOI : 10.2337/dc07-0719)

Study at Cambridge

About the University

Research at Cambridge