MRC Epidemiology Unit

 

Type 2 diabetes-associated variants of the MT melatonin receptor affect distinct modes of signaling.

Karamitri A, Plouffe B, Bonnefond A, Chen M, Gallion J, Guillaume JL, Hegron A, Boissel M, Canouil M, Langenberg C, Wareham NJ, Le Gouill C, Lukasheva V, Lichtarge O, Froguel P, Bouvier M, Jockers R

Science signaling. Aug 2018

(DOI : 10.1126/scisignal.aan6622)

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Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes.

Bonnefond A, Clément N, Fawcett K, Yengo L, Vaillant E, Guillaume JL, Dechaume A, Payne F, Roussel R, Czernichow S, Hercberg S, Hadjadj S, Balkau B, Marre M, Lantieri O, Langenberg C, Bouatia-Naji N, Charpentier G, Vaxillaire M, Rocheleau G, Wareham NJ, Sladek R, McCarthy MI, Dina C, Barroso I, Jockers R, Froguel P

Nature genetics. Sep 2011

(DOI : 10.1038/ng.1053)

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