MRC Epidemiology Unit

 

Association of insulin resistance with the accumulation of saturated intramyocellular lipid: A comparison with other fat stores.

Azhar M, Watson LPE, De Lucia Rolfe E, Ferraro M, Carr K, Worsley J, Boesch C, Hodson L, Chatterjee KK, Kemp GJ, Savage DB, Sleigh A

NMR in biomedicine. Feb 2024

(DOI : 10.1002/nbm.5117)

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Newborn body composition and child cardiovascular risk markers: a prospective multi-ethnic Asian cohort study.

Ong YY, Tint MT, Aris IM, Yuan WL, Chen LW, Fortier MV, Choo J, Ling LH, Shek L, Tan KH, Gluckman PD, Yap F, Chong YS, Godfrey KM, Chong MF, Chan SY, Eriksson JG, Wlodek ME, De Lucia Rolfe E, Ong KK, Michael N, Lee YS

International Journal of Epidemiology. Jul 2022

(DOI : 10.1093/ije/dyac154)

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Anthropometry-based prediction of body composition in early infancy compared to air-displacement plethysmography.

Olga L, van Beijsterveldt IALP, Hughes IA, Dunger DB, Ong KK, Hokken-Koelega ACS, De Lucia Rolfe E

Pediatric Obesity. Apr 2021

(DOI : 10.1111/ijpo.12818)

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Joint associations between objectively measured physical activity volume and intensity with body fatness: the Fenland study.

Lindsay T, Wijndaele K, Westgate K, Dempsey P, Strain T, De Lucia Rolfe E, Forouhi NG, Griffin S, Wareham NJ, Brage S

International Journal of Obesity. Mar 2021

(DOI : 10.1038/s41366-021-00970-8)

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Antenatal Determinants of Childhood Obesity in High-Risk Offspring: Protocol for the DiGest Follow-Up Study.

Jones D, De Lucia Rolfe E, Rennie KL, Griep LMO, Kusinski LC, Hughes DJ, Brage S, Ong KK, Beardsall K, Meek CL

Nutrients. Jan 2021

(DOI : 10.3390/nu13041156)

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Reference Values for DXA-Derived Visceral Adipose Tissue in Adults 40 Years and Older from a European Population: The Tromsø Study 2015-2016.

Lundblad MW, Jacobsen BK, Johansson J, De Lucia Rolfe E, Grimsgaard S, Hopstock LA

Journal of Obesity. Oct 2020

(DOI : 10.1155/2021/6634536)

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Dietary Intervention in Pregnant Women with Gestational Diabetes; Protocol for the DiGest Randomised Controlled Trial.

Kusinski LC, Murphy HR, De Lucia Rolfe E, Rennie KL, Oude Griep LM, Hughes D, Taylor R, Meek CL

Nutrients. Mar 2020

(DOI : 10.3390/nu12041165)

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Circulating PCSK9 is associated with liver biomarkers and hepatic steatosis.

Paquette M, Gauthier D, Chamberland A, Prat A, De Lucia Rolfe E, Rasmussen JJ, Kaduka L, Seidah NG, Bernard S, Christensen DL, Baass A

Clinical biochemistry. Aug 2019

(DOI : 10.1016/j.clinbiochem.2020.01.003)

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Associations of types of dairy consumption with adiposity: cross-sectional findings from over 12,000 adults in the Fenland Study, UK.

Trichia E, Imamura F, Brage S, De Lucia Rolfe E, Griffin SJ, Wareham NJ, Forouhi NG

The British journal of nutrition. Jul 2019

(DOI : 10.1017/S0007114519001776)

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Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.

Lotta LA, Wittemans LBL, Zuber V, Stewart ID, Sharp SJ, Luan J, Day FR, Li C, Bowker N, Cai L, De Lucia Rolfe E, Khaw KT, Perry JRB, O'Rahilly S, Scott RA, Savage DB, Burgess S, Wareham NJ, Langenberg C

JAMA. Dec 2018

(DOI : 10.1001/jama.2018.19329)

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Associations of physical activity and sedentary time with body composition in Brazilian young adults.

Silva BGCD, Silva ICMD, Ekelund U, Brage S, Ong KK, De Lucia Rolfe E, Lima NP, Silva SGD, França GVA, Horta BL

Scientific reports. Sep 2018

(DOI : 10.1038/s41598-019-41935-2)

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The association between adherence to the Mediterranean diet and hepatic steatosis: cross-sectional analysis of two independent studies, the UK Fenland Study and the Swiss CoLaus Study.

Imamura F, Brage S, De Lucia Rolfe E, Griffin SJ, Wareham NJ, Marques-Vidal P, Forouhi NG

BMC medicine. Aug 2018

(DOI : 10.1186/s12916-019-1251-7)

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Adolescent parenthood associated with adverse socio-economic outcomes at age 30 years in women and men of the Pelotas, Brazil: 1982 Birth Cohort Study.

Gigante DP, de França G, De Lucia Rolfe E, Lima NP, Dos Santos Motta JV, Gonçalves H, Horta BL, Barros FC, Ong KK

BJOG : an international journal of obstetrics and gynaecology. Jul 2018

(DOI : 10.1111/1471-0528.15428)

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Validity of ultrasonography to assess hepatic steatosis compared to magnetic resonance spectroscopy as a criterion method in older adults.

De Lucia Rolfe E, Brage S, Sleigh A, Finucane F, Griffin SJ, Wareham NJ, Ong KK, Forouhi NG

PLoS ONE. Apr 2018

(DOI : 10.1371/journal.pone.0207923)

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The associations between adult body composition and abdominal adiposity outcomes, and relative weight gain and linear growth from birth to age 22 in the Birth to Twenty Plus cohort, South Africa.

Prioreschi A, Munthali RJ, Kagura J, Said-Mohamed R, De Lucia Rolfe E, Micklesfield LK, Norris SA

PLoS ONE. Oct 2017

(DOI : 10.1371/journal.pone.0190483)

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Associations of stunting in early childhood with cardiometabolic risk factors in adulthood.

De Lucia Rolfe E, de França GVA, Vianna CA, Gigante DP, Miranda JJ, Yudkin JS, Horta BL, Ong KK

PLoS ONE. Aug 2017

(DOI : 10.1371/journal.pone.0192196)

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Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort.

de Oliveira PD, Wehrmeister FC, Horta BL, Pérez-Padilla R, de França GVA, Gigante DP, Barros FC, Ong KK, De Lucia Rolfe E, Menezes AMB

BMC pulmonary medicine. Aug 2017

(DOI : 10.1186/s12890-017-0510-7)

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Genomic ancestry and education level independently influence abdominal fat distributions in a Brazilian admixed population.

França GVA, De Lucia Rolfe E, Horta BL, Gigante DP, Yudkin JS, Ong KK, Victora CG

PLoS ONE. Jan 2017

(DOI : 10.1371/journal.pone.0179085)

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Impact of Early Infant Growth, Duration of Breastfeeding and Maternal Factors on Total Body Fat Mass and Visceral Fat at 3 and 6 Months of Age.

Breij LM, Abrahamse-Berkeveld M, Acton D, De Lucia Rolfe E, Ong KK, Hokken-Koelega ACS

Annals of nutrition & metabolism. Nov 2016

(DOI : 10.1159/000481539)

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Associations between body mass index-related genetic variants and adult body composition: The Fenland cohort study.

Clifton EA, Day FR, De Lucia Rolfe E, Forouhi NG, Brage S, Griffin SJ, Wareham NJ, Ong KK

International Journal of Obesity. Sep 2016

(DOI : 10.1038/ijo.2017.11)

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Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.

Lotta LA, Gulati P, Day FR, Payne F, Ongen H, van de Bunt M, Gaulton KJ, Eicher JD, Sharp SJ, Luan J, De Lucia Rolfe E, Stewart ID, Wheeler E, Willems SM, Adams C, Yaghootkar H, EPIC-InterAct Consortium, Cambridge FPLD1 Consortium, Forouhi NG, Khaw KT, Johnson AD, Semple RK, Frayling T, Perry JR, Dermitzakis E, McCarthy MI, Barroso I, Wareham NJ, Savage DB, Langenberg C, O'Rahilly S, Scott RA

Nature genetics. Apr 2016

(DOI : 10.1038/ng.3714)

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Validity of visceral adiposity estimates from DXA against MRI in Kuwaiti men and women.

Mohammad A, De Lucia Rolfe E, Sleigh A, Kivisild T, Behbehani K, Wareham NJ, Brage S, Mohammad T

Nutrition & diabetes. Jan 2016

(DOI : 10.1038/nutd.2016.38)

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Longitudinal fat mass and visceral fat during the first 6 months after birth in healthy infants: support for a critical window for adiposity in early life.

Breij LM, Kerkhof GF, De Lucia Rolfe E, Ong KK, Abrahamse-Berkeveld M, Acton D, Hokken-Koelega ACS

Pediatric Obesity. Sep 2015

(DOI : 10.1111/ijpo.12139)

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Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults.

De Lucia Rolfe E, Ong KK, Sleigh A, Dunger DB, Norris SA

BMC Public Health. Jun 2015

(DOI : 10.1186/s12889-015-2147-x)

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Associations of birth weight, linear growth and relative weight gain throughout life with abdominal fat depots in adulthood: the 1982 Pelotas (Brazil) birth cohort study.

Araújo de França GV, De Lucia Rolfe E, Horta BL, Gigante DP, Yudkin JS, Ong KK, Victora CG

International Journal of Obesity. Nov 2014

(DOI : 10.1038/ijo.2015.192)

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Liver fat accumulation is associated with reduced hepatic insulin extraction and beta cell dysfunction in healthy older individuals.

Finucane FM, Sharp SJ, Hatunic M, Sleigh A, De Lucia Rolfe E, Aihie Sayer A, Cooper C, Griffin SJ, Wareham NJ

Diabetology & metabolic syndrome. Jul 2013

(DOI : 10.1186/1758-5996-6-43)

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Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Older Individuals.

Finucane FM, Sharp SJ, Hatunic M, Sleigh A, De Lucia Rolfe E, Sayer AA, Cooper C, Griffin SJ, Savage DB, Wareham NJ

International journal of endocrinology. Jan 2013

(DOI : 10.1155/2013/870487)

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Ultrasound estimates of visceral and subcutaneous-abdominal adipose tissues in infancy.

De Lucia Rolfe E, Modi N, Uthaya S, Hughes IA, Dunger DB, Acerini C, Stolk RP, Ong KK

Journal of Obesity. Dec 2012

(DOI : 10.1155/2013/951954)

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Validation of ultrasound estimates of visceral fat in black South African adolescents.

De Lucia Rolfe E, Norris SA, Sleigh A, Brage S, Dunger DB, Stolk RP, Ong KK

Obesity (Silver Spring, Md.). Jul 2011

(DOI : 10.1038/oby.2011.213)

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Computed tomography-based validation of abdominal adiposity measurements from ultrasonography, dual-energy X-ray absorptiometry and anthropometry.

Gradmark AM, Rydh A, Renstrom F, De Lucia Rolfe E, Sleigh A, Nordström P, Brage S, Franks PW

The British journal of nutrition. Apr 2010

(DOI : 10.1017/S0007114510000796)

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Ultrasound measurements of visceral and subcutaneous abdominal thickness to predict abdominal adiposity among older men and women.

De Lucia Rolfe E, Sleigh A, Finucane FM, Brage S, Stolk RP, Cooper C, Sharp SJ, Wareham NJ, Ong KK

Obesity (Silver Spring, Md.). Sep 2009

(DOI : 10.1038/oby.2009.309)

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The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial.

Finucane FM, Sharp SJ, Purslow LR, Horton K, Horton J, Savage DB, Brage S, Besson H, De Lucia Rolfe E, Sleigh A, Martin HJ, Aihie Sayer A, Cooper C, Ekelund U, Griffin SJ, Wareham NJ

Diabetologia. Aug 2009

(DOI : 10.1007/s00125-009-1641-z)

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Measuring abdominal adiposity in 6 to 7-year-old children.

Liem ET, De Lucia Rolfe E, L'Abée C, Sauer PJ, Ong KK, Stolk RP

European Journal of Clinical Nutrition. Jan 2009

(DOI : 10.1038/ejcn.2008.57)

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