MRC Epidemiology Unit - Publications Database

Protein-truncating and rare missense variants in and and associations with cancer in UK Biobank whole-exome sequence data.

Mukhtar TK, Wilcox N, Dennis J, Yang X, Naven M, Mavaddat N, Perry JRB, Gardner E, Easton DF

Journal of medical genetics. Aug 2024

(DOI : 10.1136/jmg-2024-110127)

External Validation of Risk Prediction Models Incorporating Common Genetic Variants for Incident Colorectal Cancer Using UK Biobank.

Saunders CL, Kilian B, Thompson DJ, McGeoch LJ, Griffin SJ, Antoniou AC, Emery JD, Walter FM, Dennis J, Yang X, Usher-Smith JA

Cancer prevention research (Philadelphia, Pa.). Nov 2019

(DOI : 10.1158/1940-6207.CAPR-19-0521)

Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study.

van Capelleveen JC, Bernelot Moens SJ, Yang X, Kastelein JJP, Wareham NJ, Zwinderman AH, Stroes ESG, Witztum JL, Hovingh GK, Khaw KT, Boekholdt SM, Tsimikas S

Arteriosclerosis, thrombosis, and vascular biology. Jan 2017

(DOI : 10.1161/ATVBAHA.117.309007)

Fatigue is associated with excess mortality in the general population: results from the EPIC-Norfolk study.

Basu N, Yang X, Luben RN, Whibley D, Macfarlane GJ, Wareham NJ, Khaw KT, Myint PK

BMC medicine. May 2016

(DOI : 10.1186/s12916-016-0662-y)

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.

Dimas AS, Lagou V, Barker A, Knowles JW, Mägi R, Hivert MF, Benazzo A, Rybin D, Jackson AU, Stringham HM, Song C, Fischer-Rosinsky A, Boesgaard TW, Grarup N, Abbasi FA, Assimes TL, Hao K, Yang X, Lecoeur C, Barroso I, Bonnycastle LL, Böttcher Y, Bumpstead S, Chines PS, Erdos MR, Graessler J, Kovacs P, Morken MA, Narisu N, Payne F, Stančáková A, Swift AJ, Tönjes A, Bornstein SR, Cauchi S, Froguel P, Meyre D, Schwarz PE, Häring HU, Smith U, Boehnke M, Bergman RN, Collins FS, Mohlke KL, Tuomilehto J, Quertemous T, Lind L, Hansen T, Pedersen O, Walker M, Pfeiffer AF, Spranger J, Stumvoll M, Meigs JB, Wareham NJ, Kuusisto J, Laakso M, Langenberg C, Dupuis J, Watanabe RM, Florez JC, Ingelsson E, McCarthy MI, Prokopenko I

Diabetes. Dec 2013

(DOI : 10.2337/db13-0949)