MRC Epidemiology Unit

 

Lower mental health related quality of life precedes dementia diagnosis: findings from the EPIC-Norfolk prospective population-based study.

Chintapalli R, Myint PK, Brayne C, Hayat S, Keevil VL

European Journal of Epidemiology. Oct 2023

(DOI : 10.1007/s10654-023-01064-7)

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Association Between Retinal Nerve Fiber Layer Thickness and Incident Dementia in the European Prospective Investigation into Cancer in Norfolk Cohort.

Yin GS, van der Heide F, Littlejohns TJ, Kuźma E, Hayat S, Brayne C, Foster PJ, Luben R, Khawaja AP

Journal of Alzheimer's disease : JAD. Aug 2023

(DOI : 10.3233/JAD-230073)

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Evaluation of routinely collected records for dementia outcomes in UK: a prospective cohort study.

Hayat S, Luben R, Khaw KT, Wareham N, Brayne C

BMJ Open. Jun 2022

(DOI : 10.1136/bmjopen-2022-060931)

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Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke.

Rudnicka AR, Welikala R, Barman S, Foster PJ, Luben R, Hayat S, Khaw KT, Whincup P, Strachan D, Owen CG

The British journal of ophthalmology. May 2022

(DOI : 10.1136/bjo-2022-321842)

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Visual Impairment and Risk of Dementia in 2 Population-Based Prospective Cohorts: UK Biobank and EPIC-Norfolk.

Littlejohns TJ, Hayat S, Luben R, Brayne C, Conroy M, Foster PJ, Khawaja AP, Kuźma E

The journals of gerontology. Series A, Biological sciences and medical sciences. Jul 2021

(DOI : 10.1093/gerona/glab325)

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Alcohol Consumption and Incident Cataract Surgery in Two Large UK Cohorts.

Chua SYL, Luben RN, Hayat S, Broadway DC, Khaw KT, Warwick A, Britten A, Day AC, Strouthidis N, Patel PJ, Khaw PT, Foster PJ, Khawaja AP, UK Biobank Eye and Vision Consortium UK Biobank Eye and Vision Consortium

Ophthalmology. Nov 2020

(DOI : 10.1016/j.ophtha.2021.02.007)

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Risk factors for previously undiagnosed primary open-angle glaucoma: the EPIC-Norfolk Eye Study.

Chan MPY, Khawaja AP, Broadway DC, Yip J, Luben R, Hayat S, Peto T, Khaw KT, Foster PJ

The British journal of ophthalmology. Oct 2020

(DOI : 10.1136/bjophthalmol-2020-317718)

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Sociodemographic and lifestyle predictors of incident hospital admissions with multimorbidity in a general population, 1999-2019: the EPIC-Norfolk cohort.

Luben R, Hayat S, Wareham N, Pharoah PP, Khaw KT

BMJ Open. Sep 2020

(DOI : 10.1136/bmjopen-2020-042115)

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Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study.

Khawaja AP, Rojas Lopez KE, Hardcastle AJ, Hammond CJ, Liskova P, Davidson AE, Gore DM, Hafford Tear NJ, Pontikos N, Hayat S, Wareham NJ, Khaw KT, Tuft SJ, Foster PJ, Hysi PG

JAMA ophthalmology. Jun 2020

(DOI : 10.1001/jamaophthalmol.2019.2058)

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Residential area deprivation and risk of subsequent hospital admission in a British population: the EPIC-Norfolk cohort.

Luben R, Hayat S, Khawaja A, Wareham NJ, Pharoah PP, Khaw KT

BMJ Open. Dec 2019

(DOI : 10.1136/bmjopen-2019-031251)

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Usual physical activity and subsequent hospital usage over 20 years in a general population: the EPIC-Norfolk cohort.

Luben R, Hayat S, Wareham N, Pharoah P, Khaw KT

BMC geriatrics. Dec 2019

(DOI : 10.1186/s12877-020-01573-0)

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Is there a dose-response relationship between musical instrument playing and later-life cognition? A cohort study using EPIC-Norfolk data.

Walsh S, Luben R, Hayat S, Brayne C

Age and ageing. Dec 2019

(DOI : 10.1093/ageing/afaa242)

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Cardiovascular risk factors associated with polymyalgia rheumatica and giant cell arteritis in a prospective cohort: EPIC-Norfolk Study.

Yates M, Luben R, Hayat S, Mackie SL, Watts RA, Khaw KT, Wareham NJ, MacGregor AJ

Rheumatology (Oxford, England). Apr 2019

(DOI : 10.1093/rheumatology/kez289)

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Mediterranean diet adherence and cognitive function in older UK adults: the European Prospective Investigation into Cancer and Nutrition-Norfolk (EPIC-Norfolk) Study.

Shannon OM, Stephan BCM, Granic A, Lentjes M, Hayat S, Mulligan A, Brayne C, Khaw KT, Bundy R, Aldred S, Hornberger M, Paddick SM, Muniz-Tererra G, Minihane AM, Mathers JC, Siervo M

The American Journal of Clinical Nutrition. Feb 2019

(DOI : 10.1093/ajcn/nqz114)

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A Common Glaucoma-risk Variant of SIX6 Alters Retinal Nerve Fiber Layer and Optic Disc Measures in a European Population: The EPIC-Norfolk Eye Study.

Khawaja AP, Chan MPY, Yip JLY, Broadway DC, Garway-Heath DF, Viswanathan AC, Luben R, Hayat S, Hauser MA, Wareham NJ, Khaw KT, Fortune B, Allingham RR, Foster PJ

Journal of glaucoma. Jul 2018

(DOI : 10.1097/IJG.0000000000001026)

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Alcohol consumption and future hospital usage: The EPIC-Norfolk prospective population study.

Luben R, Hayat S, Mulligan A, Lentjes M, Wareham N, Pharoah P, Khaw KT

PLoS ONE. Jan 2018

(DOI : 10.1371/journal.pone.0200747)

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Glaucoma and intraocular pressure in EPIC-Norfolk Eye Study: cross sectional study.

Chan MPY, Broadway DC, Khawaja AP, Yip JLY, Garway-Heath DF, Burr JM, Luben R, Hayat S, Dalzell N, Khaw KT, Foster PJ

BMJ (Clinical research ed.). Sep 2017

(DOI : 10.1136/bmj.j3889)

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Prediction of acute myeloid leukaemia risk in healthy individuals.

Abelson S, Collord G, Ng SWK, Weissbrod O, Mendelson Cohen N, Niemeyer E, Barda N, Zuzarte PC, Heisler L, Sundaravadanam Y, Luben R, Hayat S, Wang TT, Zhao Z, Cirlan I, Pugh TJ, Soave D, Ng K, Latimer C, Hardy C, Raine K, Jones D, Hoult D, Britten A, McPherson JD, Johansson M, Mbabaali F, Eagles J, Miller JK, Pasternack D, Timms L, Krzyzanowski P, Awadalla P, Costa R, Segal E, Bratman SV, Beer P, Behjati S, Martincorena I, Wang JCY, Bowles KM, Quirós JR, Karakatsani A, La Vecchia C, Trichopoulou A, Salamanca-Fernández E, Huerta JM, Barricarte A, Travis RC, Tumino R, Masala G, Boeing H, Panico S, Kaaks R, Krämer A, Sieri S, Riboli E, Vineis P, Foll M, McKay J, Polidoro S, Sala N, Khaw KT, Vermeulen R, Campbell PJ, Papaemmanuil E, Minden MD, Tanay A, Balicer RD, Wareham NJ, Gerstung M, Dick JE, Brennan P, Vassiliou GS, Shlush LI

Nature. Jul 2017

(DOI : 10.1038/s41586-018-0317-6)

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Physical capability predicts mortality in late mid-life as well as in old age: Findings from a large British cohort study.

Keevil VL, Luben R, Hayat S, Sayer AA, Wareham NJ, Khaw KT

Archives of gerontology and geriatrics. Sep 2016

(DOI : 10.1016/j.archger.2017.10.001)

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Topical Beta-Blockers and Cardiovascular Mortality: Systematic Review and Meta-Analysis with Data from the EPIC-Norfolk Cohort Study.

Pinnock C, Yip JL, Khawaja AP, Luben R, Hayat S, Broadway DC, Foster PJ, Khaw KT, Wareham N

Ophthalmic epidemiology. Aug 2016

(DOI : 10.1080/09286586.2016.1213301)

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Retinal Nerve Fiber Layer Measures and Cognitive Function in the EPIC-Norfolk Cohort Study.

Khawaja AP, Chan MP, Yip JL, Broadway DC, Garway-Heath DF, Luben R, Hayat S, Matthews FE, Brayne C, Khaw KT, Foster PJ

Investigative ophthalmology & visual science. Apr 2016

(DOI : 10.1167/iovs.16-19067)

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Daytime napping and increased risk of incident respiratory diseases: symptom, marker, or risk factor?

Leng Y, Wainwright NW, Cappuccio FP, Surtees PG, Hayat S, Luben R, Brayne C, Khaw KT

Sleep medicine. Mar 2016

(DOI : 10.1016/j.sleep.2016.06.012)

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Predicting admissions and time spent in hospital over a decade in a population-based record linkage study: the EPIC-Norfolk cohort.

Luben R, Hayat S, Wareham N, Khaw KT

BMJ Open. Jan 2016

(DOI : 10.1136/bmjopen-2015-009461)

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Cross Sectional and Longitudinal Associations between Cardiovascular Risk Factors and Age Related Macular Degeneration in the EPIC-Norfolk Eye Study.

Yip JL, Khawaja AP, Chan MP, Broadway DC, Peto T, Luben R, Hayat S, Bhaniani A, Wareham NJ, Khaw KT, Foster PJ

PLoS ONE. Feb 2015

(DOI : 10.1371/journal.pone.0132565)

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Cross Sectional and Longitudinal Associations between Cardiovascular Risk Factors and Age Related Macular Degeneration in the EPIC-Norfolk Eye Study.

Yip JL, Khawaja AP, Chan MP, Broadway DC, Peto T, Tufail A, Luben R, Hayat S, Bhaniani A, Wareham NJ, Khaw KT, Foster PJ

PLoS ONE. Feb 2015

(DOI : 10.1371/journal.pone.0132565)

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Cross-sectional associations between different measures of obesity and muscle strength in men and women in a British cohort study.

Keevil VL, Luben R, Dalzell N, Hayat S, Sayer AA, Wareham NJ, Khaw KT

The journal of nutrition, health & aging. Jan 2015

(DOI : 10.1007/s12603-014-0492-6)

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Area deprivation and age related macular degeneration in the EPIC-Norfolk Eye Study.

Luben R, Hayat S, Wareham NJ, Khaw KT

Public Health. May 2014

(DOI : 10.1016/j.puhe.2014.10.012)

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Area deprivation and age related macular degeneration in the EPIC-Norfolk Eye Study.

Yip JL, Khawaja AP, Chan MP, Broadway DC, Peto T, Luben R, Hayat S, Bhaniani A, Wareham NJ, Foster PJ, Khaw KT

Public Health. May 2014

(DOI : 10.1016/j.puhe.2014.10.012)

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Crowdsourcing as a screening tool to detect clinical features of glaucomatous optic neuropathy from digital photography.

Mitry D, Peto T, Hayat S, Blows P, Morgan J, Khaw KT, Foster PJ

PLoS ONE. Apr 2014

(DOI : 10.1371/journal.pone.0117401)

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Daytime napping and the risk of all-cause and cause-specific mortality: a 13-year follow-up of a British population.

Leng Y, Wainwright NW, Cappuccio FP, Surtees PG, Hayat S, Luben R, Brayne C, Khaw KT

American Journal of Epidemiology. Apr 2014

(DOI : 10.1093/aje/kwu036)

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Corneal biomechanical properties and glaucoma-related quantitative traits in the EPIC-Norfolk Eye Study.

Khawaja AP, Chan MP, Broadway DC, Garway-Heath DF, Luben R, Yip JL, Hayat S, Khaw KT, Foster PJ

Investigative ophthalmology & visual science. Dec 2013

(DOI : 10.1167/iovs.13-13290)

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Visual acuity, self-reported vision and falls in the EPIC-Norfolk Eye study.

Yip JL, Khawaja AP, Broadway D, Luben R, Hayat S, Dalzell N, Bhaniani A, Wareham N, Khaw KT, Foster PJ

The British journal of ophthalmology. Dec 2013

(DOI : 10.1136/bjophthalmol-2013-304179)

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Area deprivation, individual socioeconomic status and low vision in the EPIC-Norfolk Eye Study.

Yip JL, Luben R, Hayat S, Khawaja AP, Broadway DC, Wareham N, Khaw KT, Foster PJ

Journal of Epidemiology and Community Health. Nov 2013

(DOI : 10.1136/jech-2013-203265)

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Systemic medication and intraocular pressure in a British population: the EPIC-Norfolk Eye Study.

Khawaja AP, Chan MP, Broadway DC, Garway-Heath DF, Luben R, Yip JL, Hayat S, Wareham NJ, Khaw KT, Foster PJ

Ophthalmology. Oct 2013

(DOI : 10.1016/j.ophtha.2014.02.009)

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Laser scanning tomography in the EPIC-Norfolk Eye Study: principal components and associations.

Khawaja AP, Chan MP, Broadway DC, Garway-Heath DF, Luben R, Yip JL, Hayat S, Khaw KT, Foster PJ

Investigative ophthalmology & visual science. Sep 2013

(DOI : 10.1167/iovs.13-12490)

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The small eye phenotype in the EPIC-Norfolk eye study: prevalence and visual impairment in microphthalmos and nanophthalmos.

Day AC, Khawaja AP, Peto T, Hayat S, Luben R, Broadway DC, Khaw KT, Foster PJ

BMJ Open. Jul 2013

(DOI : 10.1136/bmjopen-2013-003280)

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Associations with retinal nerve fiber layer measures in the EPIC-Norfolk Eye Study.

Khawaja AP, Chan MP, Garway-Heath DF, Broadway DC, Luben R, Sherwin JC, Hayat S, Khaw KT, Foster PJ

Investigative ophthalmology & visual science. Jul 2013

(DOI : 10.1167/iovs.13-11971)

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Crowdsourcing as a novel technique for retinal fundus photography classification: analysis of images in the EPIC Norfolk cohort on behalf of the UK Biobank Eye and Vision Consortium.

Mitry D, Peto T, Hayat S, Morgan JE, Khaw KT, Foster PJ

PLoS ONE. Jun 2013

(DOI : 10.1371/journal.pone.0071154)

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The physical capability of community-based men and women from a British cohort: the European Prospective Investigation into Cancer (EPIC)-Norfolk study.

Keevil VL, Hayat S, Dalzell N, Moore S, Bhaniani A, Luben R, Wareham NJ, Khaw KT

BMC geriatrics. May 2013

(DOI : 10.1186/1471-2318-13-93)

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The EPIC-Norfolk Eye Study: rationale, methods and a cross-sectional analysis of visual impairment in a population-based cohort.

Khawaja AP, Chan MP, Hayat S, Broadway DC, Luben R, Garway-Heath DF, Sherwin JC, Yip JL, Dalzell N, Wareham NJ, Khaw KT, Foster PJ

BMJ Open. Mar 2013

(DOI : 10.1136/bmjopen-2013-002684)

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Genotype-phenotype analysis of SNPs associated with primary angle closure glaucoma (rs1015213, rs3753841 and rs11024102) and ocular biometry in the EPIC-Norfolk Eye Study.

Day AC, Luben R, Khawaja AP, Low S, Hayat S, Dalzell N, Wareham NJ, Khaw KT, Foster PJ

The British journal of ophthalmology. Mar 2013

(DOI : 10.1136/bjophthalmol-2012-302969)

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Spectral domain optical coherence tomography imaging of the aqueous outflow structures in normal participants of the EPIC-Norfolk Eye Study.

Day AC, Garway-Heath DF, Broadway DC, Jiang Y, Hayat S, Dalzell N, Khaw KT, Foster PJ

The British journal of ophthalmology. Dec 2012

(DOI : 10.1136/bjophthalmol-2012-302147)

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The association between social stress and global cognitive function in a population-based study: the European Prospective Investigation into Cancer (EPIC)-Norfolk study.

Leng Y, Wainwright NW, Hayat S, Stephan BC, Matthews FE, Luben R, Surtees PG, Khaw KT, Brayne C

Psychological medicine. Jun 2012

(DOI : 10.1017/S0033291712001316)

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Uncorrected refractive error in older British adults: the EPIC-Norfolk Eye Study.

Sherwin JC, Khawaja AP, Broadway D, Luben R, Hayat S, Dalzell N, Wareham NJ, Khaw KT, Foster PJ

The British journal of ophthalmology. Apr 2012

(DOI : 10.1136/bjophthalmol-2011-301430)

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Intraocular pressure and corneal biomechanics in an adult British population: the EPIC-Norfolk eye study.

Foster PJ, Broadway DC, Garway-Heath DF, Yip JL, Luben R, Hayat S, Dalzell N, Wareham NJ, Khaw KT

Investigative ophthalmology & visual science. Sep 2011

(DOI : 10.1167/iovs.11-7853)

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Physical activity and ocular perfusion pressure: the EPIC-Norfolk eye study.

Yip JL, Broadway DC, Luben R, Garway-Heath DF, Hayat S, Dalzell N, Lee PS, Bhaniani A, Wareham NJ, Khaw KT, Foster PJ

Investigative ophthalmology & visual science. Sep 2011

(DOI : 10.1167/iovs.11-8267)

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Refractive error, axial length and anterior chamber depth of the eye in British adults: the EPIC-Norfolk Eye Study.

Foster PJ, Broadway DC, Hayat S, Luben R, Dalzell N, Bingham S, Wareham NJ, Khaw KT

The British journal of ophthalmology. Jul 2010

(DOI : 10.1136/bjo.2009.163899)

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Full-scale scores of the Mini Mental State Examination can be generated from an abbreviated version.

Matthews FE, Stephan BC, Khaw KT, Hayat S, Luben R, Bhaniani A, Moore S, Brayne C

Journal of clinical epidemiology. Dec 2009

(DOI : 10.1016/j.jclinepi.2010.11.014)

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