MRC Epidemiology Unit

 

High-resolution functional mapping of RAD51C by saturation genome editing.

Olvera-León R, Zhang F, Offord V, Zhao Y, Tan HK, Gupta P, Pal T, Robles-Espinoza CD, Arriaga-González FG, Matsuyama LSAS, Delage E, Dicks E, Ezquina S, Rowlands CF, Turnbull C, Pharoah P, Perry JRB, Jasin M, Waters AJ, Adams DJ

Cell. Sep 2024

(DOI : 10.1016/j.cell.2024.08.039)

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Saturation genome editing of DDX3X clarifies pathogenicity of germline and somatic variation.

Radford EJ, Tan HK, Andersson MHL, Stephenson JD, Gardner EJ, Ironfield H, Waters AJ, Gitterman D, Lindsay S, Abascal F, Martincorena I, Kolesnik-Taylor A, Ng-Cordell E, Firth HV, Baker K, Perry JRB, Adams DJ, Gerety SS, Hurles ME

Nature communications. Dec 2023

(DOI : 10.1038/s41467-023-43041-4)

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