MRC Epidemiology Unit

 

Different Intensities of Physical Activity Substituted for Sedentary Time and Risk of Type 2 Diabetes: Integration of Genetics and Wearable Data.

Shi Q, Jang H, Collings PJ, Wang M, Chen Z, Luo S, Au Yeung SL, Wan YFE, Griffin SJ, Sharp SJ, Day F, Ong KK, Brage S, Kim Y

Mayo Clinic proceedings. Oct 2025

(DOI : 10.1016/j.mayocp.2025.04.033)

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Physical Fitness, Biological Aging, and Healthy Longevity.

Chen Z, Collings PJ, Wang M, Shi Q, Luo S, Au Yeung SL, Brage S, Gonzales T, Kim Y

Journal of the American Medical Directors Association. Aug 2025

(DOI : 10.1016/j.jamda.2025.105792)

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Genetic Susceptibility to Type 2 Diabetes, Television Viewing, and Atherosclerotic Cardiovascular Disease Risk.

Wang M, Collings PJ, Day FR, Ong KK, Brage S, Sharp SJ, Jang H, Suh S, Luo S, Au Yeung SL, Kim Y

Journal of the American Heart Association. Mar 2025

(DOI : 10.1161/JAHA.124.036811)

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Prospective associations of genetic susceptibility to high blood pressure and muscle strength with incident cardiovascular disease outcomes.

Wang M, Collings PJ, Jang H, Chen Z, Luo S, Au Yeung SL, Sharp SJ, Brage S, Kim Y

Journal of hypertension. Oct 2024

(DOI : 10.1097/HJH.0000000000003900)

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Development, testing and comparison of novel lifestyle-based prediction models for risk of coronary heart disease.

Shi Q, Jang H, Wang M, Au Yeung SL, Luo S, Wan EYF, Sharp SJ, Brage S, Wareham N, Kim Y

Scientific reports. Jun 2024

(DOI : 10.1038/s41598-025-99536-1)

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Adherence to a healthy lifestyle, genetic susceptibility to abdominal obesity, cardiometabolic risk markers, and risk of coronary heart disease.

Wang M, Au Yeung SL, Luo S, Jang H, Ho HS, Sharp SJ, Wijndaele K, Brage S, Wareham NJ, Kim Y

The American Journal of Clinical Nutrition. Nov 2023

(DOI : 10.1016/j.ajcnut.2023.08.002)

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Replacing device-measured sedentary time with physical activity is associated with lower risk of coronary heart disease regardless of genetic risk.

Kim Y, Jang H, Wang M, Shi Q, Strain T, Sharp SJ, Yeung SLA, Luo S, Griffin S, Wareham NJ, Wijndaele K, Brage S

Journal of internal medicine. Aug 2023

(DOI : 10.1111/joim.13715)

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Mode of transport, genetic susceptibility, and incidence of coronary heart disease.

Jiesisibieke ZL, Panter J, Wang M, Au Yeung SL, Luo S, Jang H, Wan EYF, Brage S, Kim Y

The international journal of behavioral nutrition and physical activity. Jul 2023

(DOI : 10.1186/s12966-023-01484-4)

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Incidence of Dementia and Alzheimer's Disease, Genetic Susceptibility, and Grip Strength Among Older Adults.

Kim Y, Wang M, Sharp SJ, Au Yeung SL, Luo S, Jang H, Jiesisibieke ZL, Shi Q, Chen Z, Brage S, Sharp S

The journals of gerontology. Series A, Biological sciences and medical sciences. Dec 2022

(DOI : 10.1093/gerona/glad224)

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Genetic susceptibility, screen-based sedentary activities and incidence of coronary heart disease.

Kim Y, Yeung SLA, Sharp SJ, Wang M, Jang H, Luo S, Brage S, Wijndaele K

BMC medicine. May 2022

(DOI : 10.1186/s12916-022-02380-7)

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Associations of Genetic Susceptibility and Healthy Lifestyle with Incidence of Coronary Heart Disease and Stroke in Individuals with Hypertension.

Wang M, Brage S, Sharp SJ, Luo S, Au Yeung SL, Kim Y

European Journal of Preventive Cardiology. Mar 2022

(DOI : 10.1093/eurjpc/zwac135)

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Genetic Risk, Muscle Strength, and Incident Stroke: Findings From the UK Biobank Study.

Kim Y, Hwang S, Sharp SJ, Luo S, Au Yeung SL, Teerlink CC

Mayo Clinic proceedings. Oct 2020

(DOI : 10.1016/j.mayocp.2021.01.034)

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