MRC Epidemiology Unit
Mapping biological influences on the human plasma proteome beyond the genome.
Carrasco-Zanini J, Wheeler E, Uluvar B, Kerrison N, Koprulu M, Wareham NJ, Pietzner M, Langenberg C
Nature metabolism. Sep 2024
(DOI : 10.1038/s42255-024-01133-5)
Alwan H, Luan J, Williamson A, Carrasco-Zanini J, Stewart ID, Wareham NJ, Langenberg C, Pietzner M
EBioMedicine. Aug 2024
(DOI : 10.1016/j.ebiom.2024.105306)
Proteomic signatures improve risk prediction for common and rare diseases.
Carrasco-Zanini J, Pietzner M, Davitte J, Surendran P, Croteau-Chonka DC, Robins C, Torralbo A, Tomlinson C, Grünschläger F, Fitzpatrick N, Ytsma C, Kanno T, Gade S, Freitag D, Ziebell F, Haas S, Denaxas S, Betts JC, Wareham NJ, Hemingway H, Scott RA, Langenberg C
Nature medicine. Jul 2024
(DOI : 10.1038/s41591-024-03142-z)
Carrasco-Zanini J, Pietzner M, Koprulu M, Wheeler E, Kerrison ND, Wareham NJ, Langenberg C
The Lancet. Digital health. Jun 2024
(DOI : 10.1016/S2589-7500(24)00087-6)
Multi-omic prediction of incident type 2 diabetes.
Carrasco-Zanini J, Pietzner M, Wheeler E, Kerrison ND, Langenberg C, Wareham NJ
Diabetologia. Oct 2023
(DOI : 10.1007/s00125-023-06027-x)
Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases.
Carland C, Png G, Malarstig A, Kho PF, Gustafsson S, Michaëlsson K, Lind L, Tsafantakis E, Karaleftheri M, Dedoussis G, Ramisch A, MacDonald-Dunlop E, Klaric L, Joshi PK, Chen Y, Björck HM, Eriksson P, Carrasco-Zanini J, Wheeler E, Suhre K, Gilly A, Zeggini E, Viñuela A, Dermitzakis ET, Wilson JF, Langenberg C, Thareja G, Halama A, Schmidt F, SCALLOP Consortium SCALLOP Consortium, Zanetti D, Assimes T
Clinical proteomics. Aug 2023
(DOI : 10.1186/s12014-023-09421-0)
Circulating proteins to predict COVID-19 severity.
Su CY, Zhou S, Gonzalez-Kozlova E, Butler-Laporte G, Brunet-Ratnasingham E, Nakanishi T, Jeon W, Morrison DR, Laurent L, Afilalo J, Afilalo M, Henry D, Chen Y, Carrasco-Zanini J, Farjoun Y, Pietzner M, Kimchi N, Afrasiabi Z, Rezk N, Bouab M, Petitjean L, Guzman C, Xue X, Tselios C, Vulesevic B, Adeleye O, Abdullah T, Almamlouk N, Moussa Y, DeLuca C, Duggan N, Schurr E, Brassard N, Durand M, Del Valle DM, Thompson R, Cedillo MA, Schadt E, Nie K, Simons NW, Mouskas K, Zaki N, Patel M, Xie H, Harris J, Marvin R, Cheng E, Tuballes K, Argueta K, Scott I, Mount Sinai COVID-19 Biobank Team Mount Sinai COVID-19 Biobank Team, Greenwood CMT, Paterson C, Hinterberg MA, Langenberg C, Forgetta V, Pineau J, Mooser V, Marron T, Beckmann ND, Kim-Schulze S, Charney AW, Gnjatic S, Kaufmann DE, Merad M, Richards JB
Scientific reports. Apr 2023
(DOI : 10.1038/s41598-023-31850-y)
Proteogenomic links to human metabolic diseases.
Koprulu M, Carrasco-Zanini J, Wheeler E, Lockhart S, Kerrison ND, Wareham NJ, Pietzner M, Langenberg C
Nature metabolism. Feb 2023
(DOI : 10.1038/s42255-023-00753-7)
Proteomic signatures for identification of impaired glucose tolerance.
Carrasco-Zanini J, Pietzner M, Lindbohm JV, Wheeler E, Oerton E, Kerrison N, Simpson M, Westacott M, Drolet D, Kivimaki M, Ostroff R, Williams SA, Wareham NJ, Langenberg C
Nature medicine. Nov 2022
(DOI : 10.1038/s41591-022-02055-z)
Butler-Laporte G, Gonzalez-Kozlova E, Su CY, Zhou S, Nakanishi T, Brunet-Ratnasingham E, Morrison D, Laurent L, Afilalo J, Afilalo M, Henry D, Chen Y, Carrasco-Zanini J, Farjoun Y, Pietzner M, Kimchi N, Afrasiabi Z, Rezk N, Bouab M, Petitjean L, Guzman C, Xue X, Tselios C, Vulesevic B, Adeleye O, Abdullah T, Almamlouk N, Moussa Y, DeLuca C, Duggan N, Schurr E, Brassard N, Durand M, Del Valle DM, Thompson R, Cedillo MA, Schadt E, Nie K, Simons NW, Mouskas K, Zaki N, Patel M, Xie H, Harris J, Marvin R, Cheng E, Tuballes K, Argueta K, Scott I, Mount Sinai COVID-19 Biobank Team Mount Sinai COVID-19 Biobank Team, Greenwood CMT, Paterson C, Hinterberg M, Langenberg C, Forgetta V, Mooser V, Marron T, Beckmann N, Kenigsberg E, Charney AW, Kim-Schulze S, Merad M, Kaufmann DE, Gnjatic S, Richards JB
Clinical proteomics. Sep 2022
(DOI : 10.1186/s12014-022-09371-z)
Mapping the proteo-genomic convergence of human diseases.
Pietzner M, Wheeler E, Carrasco-Zanini J, Cortes A, Koprulu M, Wörheide MA, Oerton E, Cook J, Stewart ID, Kerrison ND, Luan J, Raffler J, Arnold M, Arlt W, O'Rahilly S, Kastenmüller G, Gamazon ER, Hingorani AD, Scott RA, Wareham NJ, Langenberg C
Science (New York, N.Y.). Oct 2021
(DOI : 10.1126/science.abj1541)
Synergistic insights into human health from aptamer- and antibody-based proteomic profiling.
Pietzner M, Wheeler E, Carrasco-Zanini J, Kerrison ND, Oerton E, Koprulu M, Luan J, Hingorani AD, Williams SA, Wareham NJ, Langenberg C
Nature communications. Jul 2021
(DOI : 10.1038/s41467-021-27164-0)
Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Pietzner M, Wheeler E, Carrasco-Zanini J, Raffler J, Kerrison ND, Oerton E, Auyeung VPW, Luan J, Finan C, Casas JP, Ostroff R, Williams SA, Kastenmüller G, Ralser M, Gamazon ER, Wareham NJ, Hingorani AD, Langenberg C
Nature communications. Jun 2020
(DOI : 10.1038/s41467-020-19996-z)
