MRC Epidemiology Unit

 

Effectiveness of Minimal Contact Interventions: An RCT.

Hajna S, Sharp SJ, Cooper AJM, Williams KM, van Sluijs EMF, Brage S, Griffin SJ, Sutton S

American Journal of Preventive Medicine. Dec 2019

(DOI : 10.1016/j.amepre.2020.10.010)

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Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.

Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Khawaja AP, Cheng CY, Höhn R, Yamashiro K, Haller T, Metspalu A, Wedenoja J, Jonas JB, Wang YX, Mitchell P, Foster PJ, Klein R, Paterson AD, Hosseini SM, Williams C, Teo YY, Tham YC, Gupta P, Zhao W, Tai ES, Huffman JE, Polasek O, Hayward C, Rudan I, Wilson JF, Joshi PK, Zeller T, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtimäki T, Raitakari OT, Biino G, Concas MP, Schwantes-An TH, Igo RP, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Rahi JS, Delcourt C, Bellenguez C, Ried JS, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, Pärssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Young TL, Saw SM, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ

Nature genetics. May 2017

(DOI : 10.1038/s41588-018-0127-7)

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Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium.

Fan Q, Guo X, Tideman JW, Williams KM, Yazar S, Hosseini SM, Howe LD, Pourcain BS, Evans DM, Timpson NJ, McMahon G, Hysi PG, Krapohl E, Wang YX, Jonas JB, Baird PN, Wang JJ, Cheng CY, Teo YY, Wong TY, Ding X, Wojciechowski R, Young TL, Pärssinen O, Oexle K, Pfeiffer N, Bailey-Wilson JE, Paterson AD, Klaver CC, Plomin R, Hammond CJ, Mackey DA, He M, Saw SM, Williams C, Guggenheim JA, CREAM Consortium

Scientific reports. Feb 2016

(DOI : 10.1038/srep25853)

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Associations with intraocular pressure across Europe: The European Eye Epidemiology (E) Consortium.

Khawaja AP, Springelkamp H, Creuzot-Garcher C, Delcourt C, Hofman A, Höhn R, Iglesias AI, Wolfs RC, Korobelnik JF, Silva R, Topouzis F, Williams KM, Bron AM, Buitendijk GH, Cachulo MD, Cougnard-Gregoire A, Dartigues JF, Hammond CJ, Pfeiffer N, Salonikiou A, van Duijn CM, Vingerling JR, Luben RN, Mirshahi A, Lamparter J, Klaver CC, Jansonius NM, Foster PJ, European Eye Epidemiology (E³) Consortium

European Journal of Epidemiology. Jan 2016

(DOI : 10.1007/s10654-016-0191-1)

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Protocol for Get Moving: a randomised controlled trial to assess the effectiveness of three minimal contact interventions to promote fitness and physical activity in working adults.

Cooper AJ, Dearnley K, Williams KM, Sharp SJ, Van Sluijs EM, Brage S, Sutton S, Griffin SJ

BMC Public Health. Mar 2015

(DOI : 10.1186/s12889-015-1654-0)

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Long-term effect of population screening for diabetes on cardiovascular morbidity, self-rated health, and health behavior.

Echouffo-Tcheugui JB, Simmons RK, Prevost AT, Williams KM, Kinmonth AL, Wareham NJ, Griffin SJ

Annals of family medicine. Mar 2015

(DOI : 10.1370/afm.1737)

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Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.

Fan Q, Verhoeven VJ, Wojciechowski R, Barathi VA, Hysi PG, Guggenheim JA, Höhn R, Vitart V, Khawaja AP, Yamashiro K, Hosseini SM, Lehtimäki T, Lu Y, Haller T, Xie J, Delcourt C, Pirastu M, Wedenoja J, Gharahkhani P, Venturini C, Miyake M, Hewitt AW, Guo X, Mazur J, Huffman JE, Williams KM, Polasek O, Campbell H, Rudan I, Vatavuk Z, Wilson JF, Joshi PK, McMahon G, St Pourcain B, Evans DM, Simpson CL, Schwantes-An TH, Igo RP, Mirshahi A, Cougnard-Gregoire A, Bellenguez C, Blettner M, Raitakari O, Kähönen M, Seppala I, Zeller T, Meitinger T, Consortium for Refractive Error and Myopia, Ried JS, Gieger C, Portas L, van Leeuwen EM, Amin N, Uitterlinden AG, Rivadeneira F, Hofman A, Vingerling JR, Wang YX, Wang X, Tai-Hui Boh E, Ikram MK, Sabanayagam C, Gupta P, Tan V, Zhou L, Ho CE, Lim W, Beuerman RW, Siantar R, Tai ES, Vithana E, Mihailov E, Khor CC, Hayward C, Luben RN, Foster PJ, Klein BE, Klein R, Wong HS, Mitchell P, Metspalu A, Aung T, Young TL, He M, Pärssinen O, van Duijn CM, Jin Wang J, Williams C, Jonas JB, Teo YY, Mackey DA, Oexle K, Yoshimura N, Paterson AD, Pfeiffer N, Wong TY, Baird PN, Stambolian D, Wilson JE, Cheng CY, Hammond CJ, Klaver CC, Saw SM, Rahi JS, Korobelnik JF, Kemp JP, Timpson NJ, Smith GD, Craig JE, Burdon KP, Fogarty RD, Iyengar SK, Chew E, Janmahasatian S, Martin NG, MacGregor S, Xu L, Schache M, Nangia V, Panda-Jonas S, Wright AF, Fondran JR, Lass JH, Feng S, Zhao JH, Khaw KT, Wareham NJ, Rantanen T, Kaprio J, Pang CP, Chen LJ, Tam PO, Jhanji V, Young AL, Döring A, Raffel LJ, Cotch MF, Li X, Yip SP, Yap MK, Biino G, Vaccargiu S, Fossarello M, Fleck B, Yazar S, Tideman JW, Tedja M, Deangelis MM, Morrison M, Farrer L, Zhou X, Chen W, Mizuki N, Meguro A, Mäkelä KM

Nature communications. Feb 2015

(DOI : 10.1038/ncomms11008)

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Prevalence of refractive error in Europe: the European Eye Epidemiology (E(3)) Consortium.

Williams KM, Verhoeven VJ, Cumberland P, Bertelsen G, Wolfram C, Buitendijk GH, Hofman A, van Duijn CM, Vingerling JR, Kuijpers RW, Höhn R, Mirshahi A, Khawaja AP, Luben RN, Erke MG, von Hanno T, Mahroo O, Hogg R, Gieger C, Cougnard-Gregoire A, Anastasopoulos E, Bron A, Dartigues JF, Korobelnik JF, Creuzot-Garcher C, Topouzis F, Delcourt C, Rahi J, Meitinger T, Fletcher A, Foster PJ, Pfeiffer N, Klaver CC, Hammond CJ

European Journal of Epidemiology. Aug 2014

(DOI : 10.1007/s10654-015-0010-0)

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Multiple behaviour change intervention and outcomes in recently diagnosed type 2 diabetes: the ADDITION-Plus randomised controlled trial.

Griffin SJ, Simmons RK, Prevost AT, Williams KM, Hardeman W, Sutton S, Brage S, Ekelund U, Parker RA, Wareham NJ, Kinmonth AL

Diabetologia. Dec 2013

(DOI : 10.1007/s00125-014-3236-6)

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Changes in diet, cardiovascular risk factors and modelled cardiovascular risk following diagnosis of diabetes: 1-year results from the ADDITION-Cambridge trial cohort.

Savory LA, Griffin SJ, Williams KM, Prevost AT, Kinmonth AL, Wareham NJ, Simmons RK

Diabetic medicine : a journal of the British Diabetic Association. Feb 2013

(DOI : 10.1111/dme.12316)

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Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial.

Simmons RK, Echouffo-Tcheugui JB, Sharp SJ, Sargeant LA, Williams KM, Prevost AT, Kinmonth AL, Wareham NJ, Griffin SJ

Lancet (London, England). Oct 2012

(DOI : 10.1016/S0140-6736(12)61422-6)

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Changes in physical activity and modelled cardiovascular risk following diagnosis of diabetes: 1-year results from the ADDITION-Cambridge trial cohort.

Barakat A, Williams KM, Prevost AT, Kinmonth AL, Wareham NJ, Griffin SJ, Simmons RK

Diabetic medicine : a journal of the British Diabetic Association. Aug 2012

(DOI : 10.1111/j.1464-5491.2012.03765.x)

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Cardiovascular risk reduction following diagnosis of diabetes by screening: 1-year results from the ADDITION-Cambridge trial cohort.

Charles M, Simmons RK, Williams KM, Roglic G, Sharp SJ, Kinmonth AL, Wareham NJ, Griffin SJ

The British journal of general practice : the journal of the Royal College of General Practitioners. Jun 2012

(DOI : 10.3399/bjgp12X649070)

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Protocol for the ADDITION-Plus study: a randomised controlled trial of an individually-tailored behaviour change intervention among people with recently diagnosed type 2 diabetes under intensive UK general practice care.

Griffin SJ, Simmons RK, Williams KM, Prevost AT, Hardeman W, Grant J, Whittle F, Boase S, Hobbis I, Brage S, Westgate K, Fanshawe T, Sutton S, Wareham NJ, Kinmonth AL

BMC Public Health. Mar 2011

(DOI : 10.1186/1471-2458-11-211)

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Who attends a UK diabetes screening programme? Findings from the ADDITION-Cambridge study.

Sargeant LA, Simmons RK, Barling RS, Butler R, Williams KM, Prevost AT, Kinmonth AL, Wareham NJ, Griffin SJ

Diabetic medicine : a journal of the British Diabetic Association. Aug 2010

(DOI : 10.1111/j.1464-5491.2010.03056.x)

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The ADDITION-Cambridge trial protocol: a cluster -- randomised controlled trial of screening for type 2 diabetes and intensive treatment for screen-detected patients.

Echouffo-Tcheugui JB, Simmons RK, Williams KM, Barling RS, Prevost AT, Kinmonth AL, Wareham NJ, Griffin SJ

BMC Public Health. Mar 2009

(DOI : 10.1186/1471-2458-9-136)

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How much might cardiovascular disease risk be reduced by intensive therapy in people with screen-detected diabetes?

Echouffo-Tcheugui JB, Sargeant LA, Prevost AT, Williams KM, Barling RS, Butler R, Fanshawe T, Kinmonth AL, Wareham NJ, Griffin SJ

Diabetic medicine : a journal of the British Diabetic Association. Dec 2008

(DOI : 10.1111/j.1464-5491.2008.02600.x)

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Efficacy of a theory-based behavioural intervention to increase physical activity in an at-risk group in primary care (ProActive UK): a randomised trial.

Kinmonth AL, Wareham NJ, Hardeman W, Sutton S, Prevost AT, Fanshawe T, Williams KM, Ekelund U, Spiegelhalter D, Griffin SJ

Lancet (London, England). Jan 2008

(DOI : 10.1016/S0140-6736(08)60070-7)

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