MRC Epidemiology Unit

 

Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.

Keaton JM, Kamali Z, Xie T, Vaez A, Williams A, Goleva SB, Ani A, Evangelou E, Hellwege JN, Yengo L, Young WJ, Traylor M, Giri A, Zheng Z, Zeng J, Chasman DI, Morris AP, Caulfield MJ, Hwang SJ, Kooner JS, Conen D, Attia JR, Morrison AC, Loos RJF, Kristiansson K, Schmidt R, Hicks AA, Pramstaller PP, Nelson CP, Samani NJ, Risch L, Gyllensten U, Melander O, Riese H, Wilson JF, Campbell H, Rich SS, Psaty BM, Lu Y, Rotter JI, Guo X, Rice KM, Vollenweider P, Sundström J, Langenberg C, Tobin MD, Giedraitis V, Luan J, Tuomilehto J, Kutalik Z, Ripatti S, Salomaa V, Girotto G, Trompet S, Jukema JW, van der Harst P, Ridker PM, Giulianini F, Vitart V, Goel A, Watkins H, Harris SE, Deary IJ, van der Most PJ, Oldehinkel AJ, Keavney BD, Hayward C, Campbell A, Boehnke M, Scott LJ, Boutin T, Mamasoula C, Järvelin MR, Peters A, Gieger C, Lakatta EG, Cucca F, Hui J, Knekt P, Enroth S, de Borst MH, Polasek O, Concas MP, Catamo E, Cocca M, Li-Gao R, Hofer E, Schmidt H, Spedicati B, Waldenberger M, Strachan DP, Laan M, Teumer A, Dörr M, Gudnason V, Cook JP, Ruggiero D, Kolcic I, Boerwinkle E, Traglia M, Lehtimäki T, Raitakari OT, Johnson AD, Newton-Cheh C, Brown MJ, Dominiczak AF, Sever PJ, Poulter N, Chambers JC, Elosua R, Siscovick D, Esko T, Metspalu A, Strawbridge RJ, Laakso M, Hamsten A, Hottenga JJ, de Geus E, Morris AD, Palmer CNA, Nolte IM, Milaneschi Y, Marten J, Wright A, Zeggini E, Howson JMM, O'Donnell CJ, Spector T, Nalls MA, Simonsick EM, Liu Y, van Duijn CM, Butterworth AS, Danesh JN, Menni C, Wareham NJ, Khaw KT, Sun YV, Wilson PWF, Cho K, Visscher PM, Denny JC, Million Veteran Program Million Veteran Program, Lifelines Cohort Study Lifelines Cohort Study, CHARGE consortium CHARGE consortium, ICBP Consortium ICBP Consortium, Levy D, Edwards TL, Munroe PB, Snieder H, Warren HR

Nature genetics. Apr 2024

(DOI : 10.1038/s41588-024-01714-w)

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Ethnic differences in cross-sectional associations between impaired glucose regulation, identified by oral glucose tolerance test or HbA1c values, and cardiovascular disease in a cohort of European and South Asian origin.

Eastwood SV, Tillin T, Mayet J, Shibata DK, Wright A, Heasman J, Beauchamp N, Forouhi NG, Hughes AD, Chaturvedi N

Diabetic medicine : a journal of the British Diabetic Association. Aug 2015

(DOI : 10.1111/dme.12895)

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Estimation of Free-Living Energy Expenditure by Heart Rate and Movement Sensing: A Doubly-Labelled Water Study.

Brage S, Westgate K, Franks PW, Stegle O, Wright A, Ekelund U, Wareham NJ

PLoS ONE. Jan 2015

(DOI : 10.1371/journal.pone.0137206)

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Ethnic differences in associations between fat deposition and incident diabetes and underlying mechanisms: the SABRE study.

Eastwood SV, Tillin T, Dehbi HM, Wright A, Forouhi NG, Godsland I, Whincup P, Sattar N, Hughes AD, Chaturvedi N

Obesity (Silver Spring, Md.). Sep 2014

(DOI : 10.1002/oby.20997)

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Thigh fat and muscle each contribute to excess cardiometabolic risk in South Asians, independent of visceral adipose tissue.

Eastwood SV, Tillin T, Wright A, Mayet J, Godsland I, Forouhi NG, Whincup P, Hughes AD, Chaturvedi N

Obesity (Silver Spring, Md.). Oct 2013

(DOI : 10.1002/oby.20796)

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Estimation of CT-derived abdominal visceral and subcutaneous adipose tissue depots from anthropometry in Europeans, South Asians and African Caribbeans.

Eastwood SV, Tillin T, Wright A, Heasman J, Willis J, Godsland IF, Forouhi N, Whincup P, Hughes AD, Chaturvedi N

PLoS ONE. May 2013

(DOI : 10.1371/journal.pone.0075085)

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Estimation of daily energy expenditure in pregnant and non-pregnant women using a wrist-worn tri-axial accelerometer.

van Hees VT, Renstrom F, Wright A, Gradmark A, Catt M, Chen KY, Löf M, Bluck L, Pomeroy J, Wareham NJ, Ekelund U, Brage S, Franks PW

PLoS ONE. Feb 2011

(DOI : 10.1371/journal.pone.0022922)

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Accuracy and validity of a combined heart rate and motion sensor for the measurement of free-living physical activity energy expenditure in adults in Cameroon.

Assah FK, Ekelund U, Brage S, Wright A, Mbanya JC, Wareham NJ

International Journal of Epidemiology. Jun 2010

(DOI : 10.1093/ije/dyq098)

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Physical activity energy expenditure of adolescents in India.

Corder KL, Brage S, Wright A, Ramachandran A, Snehalatha C, Yamuna A, Wareham NJ, Ekelund U

Obesity (Silver Spring, Md.). Feb 2010

(DOI : 10.1038/oby.2010.4)

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Predicting physical activity energy expenditure using accelerometry in adults from sub-Sahara Africa.

Assah FK, Ekelund U, Brage S, Corder KL, Wright A, Mbanya JC, Wareham NJ

Obesity (Silver Spring, Md.). Feb 2009

(DOI : 10.1038/oby.2009.39)

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Is it possible to assess free-living physical activity and energy expenditure in young people by self-report?

Corder KL, Van Sluijs EM, Wright A, Whincup P, Wareham NJ, Ekelund U

The American Journal of Clinical Nutrition. Jan 2009

(DOI : 10.3945/ajcn.2008.26739)

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The 'Walking for Wellbeing in the West' randomised controlled trial of a pedometer-based walking programme in combination with physical activity consultation with 12 month follow-up: rationale and study design.

Fitzsimons CF, Baker G, Wright A, Nimmo MA, Ward Thompson C, Lowry R, Millington C, Shaw R, Fenwick E, Ogilvie D, Inchley J, Foster CE, Mutrie N

BMC Public Health. Apr 2008

(DOI : 10.1186/1471-2458-8-259)

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